Characterization of C57BL/6 plasmacytomas lacking a c-myc translocation.

abstract：:Renal-cell carcinomas (RCC) are clinically, histologically and cytogenetically very heterogeneous. The present histological WHO classification shows no clear correlation between histologic subtypes and specific chromosomal abnormalities. In 1986, a new classification was proposed by Thoenes and Störkel based on the ce...

journal_title：International journal of cancer

authors： van den Berg E,van der Hout AH,Oosterhuis JW,Störkel S,Dijkhuizen T,Dam A,Zweers HM,Mensink HJ,Buys CH,de Jong B

更新日期：1993-09-09 00:00:00

abstract：:In Japan, cervical cancer incidence has increased since the late 1990s especially among young women, despite a decreasing trend in most developed countries. Here, we examined age, period and birth cohort trends in cervical cancer incidence rates from 1985 to 2012. Incidence rates were ascertained using three populatio...

journal_title：International journal of cancer

authors： Utada M,Chernyavskiy P,Lee WJ,Franceschi S,Sauvaget C,de Gonzalez AB,Withrow DR

更新日期：2019-05-01 00:00:00

abstract：:Freshly isolated human peripheral blood monocytes from healthy volunteers are not cytotoxic to allogeneic A375 melanoma cells, but they were rendered tumoricidal by incubation in vitro with either liposomes containing 5 micrograms/mumol phospholipid of muramyl tripeptide phosphatidylethanolamine (liposome-MTP-PE; opti...

journal_title：International journal of cancer

authors： Sone S,Tandon P,Utsugi T,Ogawara M,Shimizu E,Nii A,Ogura T

更新日期：1986-10-15 00:00:00

abstract：:Colibactin-producing E. coli (CoPEC) are frequently detected in colorectal cancer (CRC) and exhibit procarcinogenic properties. Because increasing evidence show the role of immune environment and especially of antitumor T-cells in CRC development, we investigated the impact of CoPEC on these cells in human CRC and in ...

journal_title：International journal of cancer

authors： Lopès A,Billard E,Casse AH,Villéger R,Veziant J,Roche G,Carrier G,Sauvanet P,Briat A,Pagès F,Naimi S,Pezet D,Barnich N,Dumas B,Bonnet M

更新日期：2020-06-01 00:00:00

abstract：:Tumour cell anaerobic metabolism has been reported to be a prognostic factor in colorectal cancer. The present study investigated the association between monocarboxylate transporter (MCT) 1, MCT 2, lactate dehydrogenase (LDH) 1 and LDH 5, the tumour microenvironment, and outcome in patients with colorectal cancer. A c...

journal_title：International journal of cancer

authors： Roseweir AK,Clark J,McSorley ST,vanWyk HC,Quinn JA,Horgan PG,McMillan DC,Park JH,Edwards J

更新日期：2019-05-01 00:00:00

abstract：:The CpG island methylator phenotype (CIMP) with widespread promoter CpG island methylation is a phenotype in colorectal cancer, associated with microsatellite instability (MSI) and BRAF mutation. Genome-wide hypomethylation may also play an important role in genomic instability. However, the relation between global DN...

journal_title：International journal of cancer

authors： Ogino S,Kawasaki T,Nosho K,Ohnishi M,Suemoto Y,Kirkner GJ,Fuchs CS

更新日期：2008-06-15 00:00:00

abstract：:Immunotherapy targeting programmed cell death-1 (PD-1) has become a standard pharmacological therapy. Although tumor mutation burden level was reported to depend on the tumor location in nonsmall cell lung cancer (NSCLC), predictive impact of the tumor location on the response to anti-PD-1 therapy is unknown. Two hund...

journal_title：International journal of cancer

authors： Takamori S,Takada K,Shimokawa M,Matsubara T,Haratake N,Miura N,Toyozawa R,Yamaguchi M,Takenoyama M,Yoneshima Y,Tanaka K,Okamoto I,Tagawa T,Mori M

更新日期：2020-10-15 00:00:00

abstract：:Epidemiological studies of in situ breast cancer are sparse, and the role of reproductive history, an established risk modifier for invasive breast cancer, remains incompletely investigated. To examine possible associations with parity and age at first birth, we undertook a case-control study nested in a nationwide co...

journal_title：International journal of cancer

authors： Lambe M,Hsieh CC,Tsaih SW,Ekbom A,Trichopoulos D,Adami HO

更新日期：1998-07-29 00:00:00

abstract：:Non-neoplastic mesenchymal cells, along with 33 benign and 87 malignant soft-tissue tumors (STT) were examined for expression of HLA-A,B,C, beta 2-microglobulin (beta 2m), HLA-DR, -DP, and -DQ molecules and the HLA-D associated invariant chain (Ii). Serial frozen sections were immunostained using monoclonal antibodies...

journal_title：International journal of cancer

authors： Mechtersheimer G,Staudter M,Majdic O,Dörken B,Moldenhauer G,Möller P

更新日期：1990-11-15 00:00:00

abstract：:We have established 3 new EBV-negative cell lines, designated Sc-1, Ri-1 and Ci-1, from patients with B-cell lymphoma/leukemia. We characterized them by cytogenetics and by study of surface membrane antigens with a panel of monoclonal antibodies (MAbs), surface and cytoplasmic immunoglobulin (Ig) expression and Ig hea...

journal_title：International journal of cancer

authors： Th'ng KH,Garewal G,Kearney L,Rassool F,Melo JV,White H,Catovsky D,Foroni L,Luzzatto L,Goldman JM

更新日期：1987-01-15 00:00:00

abstract：:The development of reliable gene expression profiling technology is having an increasing impact on our understanding of lung cancer biology. Our study aimed to determine any correlation between the phenotypic heterogeneity and genetic diversity of lung cancer. Microarray analysis was performed on a set of 46 tumor sam...

journal_title：International journal of cancer

authors： Sanchez-Palencia A,Gomez-Morales M,Gomez-Capilla JA,Pedraza V,Boyero L,Rosell R,Fárez-Vidal ME

更新日期：2011-07-15 00:00:00

abstract：:A deficit in colorectal cancer survival in Denmark and in the UK compared to Sweden, Norway and Finland was found in the EUROCARE studies. We set out to explore if these differences still exist. Patients diagnosed with colorectal cancer as their first invasive cancer at age 15-89 in the period 1994-2000 were identifie...

journal_title：International journal of cancer

authors： Engholm G,Kejs AM,Brewster DH,Gaard M,Holmberg L,Hartley R,Iddenden R,Møller H,Sankila R,Thomson CS,Storm HH

更新日期：2007-09-01 00:00:00

abstract：:We previously demonstrated that leptin, an adipose-derived hormone, induces cell proliferation in a model of preneoplastic (IMCE (Apc(Min/+)), but not normal (YAMC (Apc(+/+)), colon epithelial cells by inducing autocrine IL-6 production and trans-IL-6 signaling. Low serum adiponectin is associated with colon, prostate...

journal_title：International journal of cancer

authors： Fenton JI,Birmingham JM,Hursting SD,Hord NG

更新日期：2008-06-01 00:00:00

abstract：:The Japanese have a much lower incidence of nonmelanoma skin cancers (NMSCs) than Caucasians, presumably due in part to their skin type conferring relative protection from ultraviolet light radiation (UVR). To examine the contribution of environmental or endogenous mutagens other than UVR, which are expected to be rel...

journal_title：International journal of cancer

authors： Takata M,Rehman I,Rees JL

更新日期：1997-05-02 00:00:00

abstract：:Replacement of normal urothelium by pre-cancerous epithelium may explain the high recurrence rate of human bladder cancer. An in vitro model was designed in order to study the mechanisms of expansion of transformed urothelial cells at the expense of normal urothelium. For this purpose, mouse bladder explants were allo...

journal_title：International journal of cancer

authors： Rebel JM,de Boer WI,Thijssen CD,Vermey M,Zwarthoff EC,van der Kwast TH

更新日期：1993-07-09 00:00:00

abstract：:We report a population based case-control study of exposure to pesticides as risk factor for non-Hodgkin lymphoma (NHL). Male and female subjects aged 18-74 years living in Sweden were included during December 1, 1999, to April 30, 2002. Controls were selected from the national population registry. Exposure to differe...

journal_title：International journal of cancer

authors： Eriksson M,Hardell L,Carlberg M,Akerman M

更新日期：2008-10-01 00:00:00

abstract：:People living with lymphohematopoietic neoplasms (LHNs) are known to have increased risks of second cancer; however, the incidence of second cancers after LHNs has not been studied extensively in Australia. The Australian Cancer Database was used to analyze site-specific risk of second primary cancer after LHNs in 127...

journal_title：International journal of cancer

authors： Royle JS,Baade P,Joske D,Fritschi L

更新日期：2011-08-15 00:00:00

abstract：:Two large-scale randomized screening trials, the Prostate, Lung, Colorectal and Ovary (PLCO) cancer trial in the USA and the European Randomized Screening for Prostate Cancer (ERSPC) trial in Europe are currently under way, aimed at assessing whether screening reduces prostate cancer mortality. Up to the end of 1998, ...

journal_title：International journal of cancer

authors： de Koning HJ,Auvinen A,Berenguer Sanchez A,Calais da Silva F,Ciatto S,Denis L,Gohagan JK,Hakama M,Hugosson J,Kranse R,Nelen V,Prorok PC,Schröder FH,European Randomized Screening for Prostate Cancer (ERSPC) Trial.,Internationa

更新日期：2002-01-10 00:00:00

abstract：:Squamous cell carcinoma of the esophagus has an uneven geographic distribution, with a high incidence in the Transkei region of Eastern Cape Province, South Africa. The precise molecular events associated with tumorigenesis of esophageal cancer in this region have not been characterized. DNA from human esophageal squa...

journal_title：International journal of cancer

authors： Gamieldien W,Victor TC,Mugwanya D,Stepien A,Gelderblom WC,Marasas WF,Geiger DH,van Helden PD

更新日期：1998-11-23 00:00:00

abstract：:Etiological risk factors for proximal (right-sided) colon cancers may be different to those of distal colon and rectal (left-sided) cancers if these tumors develop along distinct pathways. The CpG Island Methylator Phenotype (CIMP+) occurs in approximately 15% of colorectal cancers (CRC) and predominantly in the proxi...

journal_title：International journal of cancer

authors： Iacopetta B,Heyworth J,Girschik J,Grieu F,Clayforth C,Fritschi L

更新日期：2009-07-01 00:00:00

abstract：:We examined the geospatial dimension of delays to diagnosis of breast cancer in a prospective study of 1541 women newly diagnosed in the African Breast Cancer - Disparities in Outcomes (ABC-DO) Study. Women were recruited at cancer treatment facilities in Namibia, Nigeria, Uganda, and Zambia. The baseline interview in...

journal_title：International journal of cancer

authors： Togawa K,Anderson BO,Foerster M,Galukande M,Zietsman A,Pontac J,Anele A,Adisa C,Parham G,Pinder LF,McKenzie F,Schüz J,Dos-Santos-Silva I,McCormack V

更新日期：2020-11-16 00:00:00

abstract：:Oncogene-transformed fibroblasts which expressed IL-1, spontaneously or after activation with conditioned medium (CM) and lipopolysaccharide (LPS), regressed in the syngeneic host. Since regression was significantly influenced by the immune competence of the host (see companion report), we speculated that regression w...

journal_title：International journal of cancer

authors： Zöller M,Douvdevani A,Segal S,Apte RN

更新日期：1992-02-01 00:00:00

abstract：:The effects of DL-alpha-difluoromethylornithine (DFMO), a specific irreversible inhibitor of ornithine decarboxylase, on the growth of experimental mouse B16-F10 melanoma cells were investigated. DFMO (3%) in drinking water was administered to B16-F10 melanoma-bearing mice. At 24 days, B16-F10 melanomas in DFMO-fed mi...

journal_title：International journal of cancer

authors： Kubota S,Ohsawa N,Takaku F

更新日期：1987-02-15 00:00:00

abstract：:HER2 represents an important signaling pathway in breast and other cancers. Herceptin has demonstrated clinical activity, but resistance is common. Thus, new therapeutic approaches to the HER2 pathway are needed. Grb2 is an adaptor protein involved in Ras-dependent signaling induced by HER2 receptors. A specific Grb2-...

journal_title：International journal of cancer

authors： Gril B,Vidal M,Assayag F,Poupon MF,Liu WQ,Garbay C

更新日期：2007-07-15 00:00:00

abstract：:The role of different types of alcoholic beverage on cancer of the upper digestive tract was investigated in a case-control study conducted in the northern part of Italy on 305 male cases of cancer of the oral cavity and pharynx, 288 of oesophageal cancer and 1621 controls admitted to hospital for acute, non-neoplasti...

journal_title：International journal of cancer

authors： Barra S,Franceschi S,Negri E,Talamini R,La Vecchia C

更新日期：1990-12-15 00:00:00

abstract：:We evaluated the impact of a family history of breast/ovarian cancer on the risk of secondary leukemia following breast cancer. At the Geneva cancer registry, we identified 4,397 patients diagnosed with invasive breast cancer between 1990 and 2004. Patients were followed up for leukemia until the end of 2005. Family h...

journal_title：International journal of cancer

authors： Verkooijen HM,Fioretta G,Rapiti E,Vlastos G,Neyroud-Caspar I,Chappuis PO,Bouchardy C

更新日期：2008-03-01 00:00:00

abstract：:The expression patterns of glycolipids of human renal-cell carcinoma were studied in primary tumors from 23 cases and 5 metastatic lesions from 4 cases using HPTLC (high-performance thin-layer chromatography). The expression pattern of glycolipids in primary tumors was characteristic of the histological cell type. In ...

journal_title：International journal of cancer

authors： Saito S,Orikasa S,Ohyama C,Satoh M,Fukushi Y

更新日期：1991-09-30 00:00:00

abstract：:Eight squirrel monkeys (Saimiri sciureus) challenged with EBV or EBV-transformed SLCL were naturally or experimentally infected with Plasmodium knowlesi or Pl. brasilianum. Most of the animals had been splenectomized and unilaterally nephrectomized. Three of these monkeys received one dose of 6 to 12 X 10(8) autologou...

journal_title：International journal of cancer

authors： Leibold W,Huldt G,Flanagan TD,Andersson M,Dalens M,Wright DH,Voller A,Klein G

更新日期：1976-04-15 00:00:00

abstract：:Fibrin deposition in the microenvironment of tumor cells may be critical to tumor growth and metastasis formation. Procoagulant activities of tumor cells themselves, or of infiltrating macrophages, activated by the host's immune system to the tumor, may both contribute to coagulopathies associated with metastases. Lym...

journal_title：International journal of cancer

authors： Geczy CL,Ryan J,Walsh J,Goldstein D

更新日期：1986-05-15 00:00:00

abstract：:Lysyl oxidase (LOX), a copper-dependent amine oxidase, has been implicated in tumor suppression and cell growth regulation. The chromosomal locus of LOX, 5q23, is affected by loss of heterozygosity (LOH) in colon cancer, suggesting that the LOX gene could be affected by LOH and consequently, loss or reduction of LOX f...

journal_title：International journal of cancer

authors： Csiszar K,Fong SF,Ujfalusi A,Krawetz SA,Salvati EP,Mackenzie JW,Boyd CD

更新日期：2002-02-10 00:00:00