Charting of type II glucocorticoid receptor-like immunoreactivity in the rat central nervous system.

abstract：:Repeated induction of a temporary threshold shift (TTS) may result in a permanent threshold shift (PTS) and is thought to be associated with early onset of age-related hearing loss (ARHL). The possibility that a PTS might be induced by administration of repeated TTS-inducing noise exposures (NEs) over a short period d...

journal_title：Neuroscience

authors： Luo Y,Qu T,Song Q,Qi Y,Yu S,Gong S,Liu K,Jiang X

更新日期：2020-03-01 00:00:00

abstract：:The tachykinin NK3 receptor (NK3R) is a G-protein coupled receptor that is activated, internalized, and trafficked to the nuclei of magnocellular neurons in the paraventricular nucleus of the hypothalamus (PVN) in response to acute hyperosmolarity. The lack of information on the nuclear import pathway raises concerns ...

journal_title：Neuroscience

authors： Jensen DD,Sundstrom K,Flynn FW

更新日期：2010-11-10 00:00:00

abstract：:Following a Pavlovian pairing procedure, alcohol-paired cues come to elicit behavioral responses that lead to alcohol consumption. Here we used an optogenetic approach to activate basolateral amygdala (BLA) axonal terminals targeting the shell of nucleus accumbens (AcbSh) and investigated a possible influence over cue...

journal_title：Neuroscience

authors： Millan EZ,Kim HA,Janak PH

更新日期：2017-09-30 00:00:00

abstract：:Migration of postmitotic neurons in the developing cortex along radial glial fiber is essential for the formation of cortical layers. Several neurological diseases are caused by defects in neuronal migration, underlining the importance of this process for brain function. Multiple molecules are involved in this process...

journal_title：Neuroscience

authors： Wang JT,Song LZ,Li LL,Zhang W,Chai XJ,An L,Chen SL,Frotscher M,Zhao ST

更新日期：2015-04-30 00:00:00

abstract：:Huntington's disease (HD) is a severe genetically inherited neurodegenerative disorder. Patients present with three principal phenotypes of motor symptoms: choreatic, hypokinetic-rigid and mixed. The Q175 mouse model of disease offers an opportunity to investigate the cellular basis of the hypokinetic-rigid form of HD...

journal_title：Neuroscience

authors： Rothe T,Deliano M,Wójtowicz AM,Dvorzhak A,Harnack D,Paul S,Vagner T,Melnick I,Stark H,Grantyn R

更新日期：2015-12-17 00:00:00

abstract：:Age-related functional alterations in a variety of neurotransmitter systems result in modulation of interneuronal communications which has some relevance in neurological deficits observed in the aging process. The synergistic interactions between protein kinase and inositol 1,4,5-trisphosphate (insP3)/Ca2+ pathways un...

journal_title：Neuroscience

authors： Igwe OJ,Filla MB

更新日期：1995-12-01 00:00:00

abstract：:X-linked forms of non-specific mental retardation are complex disorders, for which mutations in several genes have recently been identified. These include OPHN1, GDI1, PAK3, IL1RAPL, TM4SF2, FMR2 and RSK2. To investigate the mechanisms through which alterations of these gene products could result in cognitive impairme...

journal_title：Neuroscience

authors： Boda B,Mas C,Muller D

更新日期：2002-01-01 00:00:00

abstract：:The effects of two benzodiazepines, diazepam and triazolam, on long-term potentiation were tested in slices of hippocampus and piriform cortex. The drugs had little influence on baseline synaptic responses but both were very effective in blocking LTP elicited by theta pattern stimulation. The effects were fully revers...

journal_title：Neuroscience

authors： del Cerro S,Jung M,Lynch G

更新日期：1992-07-01 00:00:00

abstract：:The distribution of CA3 hippocampal axonal terminal fields undergo a period of widespread connectivity-based changes in the early postnatal stages of life. The purpose of the current study was to examine the effect of acute phthalate exposure during this period of hippocampal development (postnatal days 16-22 (p16-p22...

journal_title：Neuroscience

authors： Smith CA,Macdonald A,Holahan MR

更新日期：2011-10-13 00:00:00

abstract：:The nucleus retroambiguus in the cat has been shown to receive strong projections from the periaqueductal gray and to send fibres to distinct motoneuronal cell groups in brainstem and spinal cord. The nucleus retroambiguus plays a role in the production of vocalization and possibly copulatory (lordosis and mounting) b...

journal_title：Neuroscience

authors： Holstege G,Kerstens L,Moes MC,Vanderhorst VG

更新日期：1997-09-01 00:00:00

abstract：:The identification of leptin and a range of novel anorectic and orexigenic peptides has focussed attention on the neural circuitry involved in the genesis of food intake and the reflex control of thermogenesis. Here, the neurotropic virus pseudorabies has been utilised in conjunction with the immunocytochemical locali...

journal_title：Neuroscience

authors： Oldfield BJ,Giles ME,Watson A,Anderson C,Colvill LM,McKinley MJ

更新日期：2002-01-01 00:00:00

abstract：:Electrophysiological and anatomical studies were carried out in parallel to investigate the ability of lateral geniculate body neurons to regenerate axons damaged by the removal of the primary visual cortex and to innervate graft neurons functionally after transplantation of fetal neocortical tissue to a lesion cavity...

journal_title：Neuroscience

authors： Girman SV

更新日期：1994-06-01 00:00:00

abstract：:Alzheimer's disease (AD) is a progressive neurodegenerative disorder, with no effective method for its treatment so far. The pathogenesis of AD has been reported, but the endogenous metabolic profile and disease-related biomarkers are still not clear. To better understand AD, an AD model induced by injecting β-amyloid...

journal_title：Neuroscience

authors： Liu Y,Wei M,Yue K,Hu M,Li S,Men L,Pi Z,Liu Z,Liu Z

更新日期：2018-12-01 00:00:00

abstract：:Free radicals have been implicated in a number of pathological conditions. To evaluate the neurophysiological consequences of free radical exposure, slices of hippocampus isolated from guinea-pigs were exposed to hydrogen peroxide which reacts with tissue iron to generate hydroxyl free radicals. Long-term potentiation...

journal_title：Neuroscience

authors： Pellmar TC,Hollinden GE,Sarvey JM

更新日期：1991-01-01 00:00:00

abstract：:In the dog cerebral cortex and spinal cord, [3H]bremazocine and [3H]U69593 both bound with high affinity to an apparent single population of binding sites under kappa-selective conditions. In the cortex similar Bmax values for both radioligands in the saturation studies and the high affinity of the kappa-selective age...

journal_title：Neuroscience

authors： Hunter JC,Birchmore B,Woodruff R,Hughes J

更新日期：1989-01-01 00:00:00

abstract：:Cytochrome oxidase is the terminal enzyme in the mitochondrial respiratory chain engaged in oxidative metabolism and energy production. In mammals, the holoenzyme is composed of 13 subunits encoded by both nuclear and mitochondrial genomes. The goal of the present study was to compare the effect of afferent impulse bl...

journal_title：Neuroscience

authors： Liu S,Wong-Riley M

更新日期：1995-07-01 00:00:00

abstract：:The acute behavioural and metabolic consequences of functional changes following unilateral intracaudate kainic acid at the level of the feline caudate nucleus, the substantia nigra pars reticulata and the deeper layers of the colliculus superior were investigated. The present study became possible since it was previo...

journal_title：Neuroscience

authors： Jaspers RM,Berkelbach van der Sprenkel JW,Cools AR

更新日期：1989-01-01 00:00:00

abstract：:Stress affects brain activity and promotes long-term changes in multiple neural systems. Exposure to stressors causes substantial effects on the perception and response to pain. In several animal models, chronic stress produces lasting hyperalgesia. The insular (IC) and anterior cingulate cortices (ACC) are the region...

journal_title：Neuroscience

authors： Imbe H,Kimura A,Donishi T,Kaneoke Y

更新日期：2014-02-14 00:00:00

abstract：:Long-term changes in synaptic transmission between neurons in the brain are considered the cellular basis of learning and memory. Over the last few decades, many studies have revealed that the precise order and timing of activity between pre- and post-synaptic cells ("spike-timing-dependent plasticity; STDP") is cruci...

journal_title：Neuroscience

authors： Fuenzalida M,Chiu CQ,Chávez AE

更新日期：2020-08-20 00:00:00

abstract：:The pattern of expression of p75, the low affinity nerve growth factor receptor, in the adult rat cerebellum and its fate after a traumatic lesion were analysed using immunohistochemical localization of this receptor. A subset of Purkinje cells was immunoreactive for low affinity nerve growth factor receptor in the in...

journal_title：Neuroscience

authors： Dusart I,Morel MP,Sotelo C

更新日期：1994-11-01 00:00:00

abstract：:Mesopontine cholinergic neurons have been implicated in the initiation and maintenance of rapid eye movement sleep via their efferent connections to the thalamus and the medial pontine reticular formation. As a first step toward understanding how these modulatory neurons integrate synaptic input, we have investigated ...

journal_title：Neuroscience

authors： Surkis A,Taylor B,Peskin CS,Leonard CS

更新日期：1996-09-01 00:00:00

abstract：:Although extensively investigated in socio-cognitive neuroscience, empathy is difficult to study. The first difficulty originates in its multifaceted nature. According to the multidimensional model, empathy combines emotional, automatic (simulation), cognitive (mentalizing) and regulatory (executive functions) process...

journal_title：Neuroscience

authors： Thirioux B,Mercier MR,Blanke O,Berthoz A

更新日期：2014-05-16 00:00:00

abstract：:The radioligands [3H]SCH 23390 and [3H]spiroperidol were used to label dopamine D1 and D2 receptors, respectively, in rat brain slices. Striatal sections were incubated in one of various concentrations of radioligand in the presence or absence of (+)-butaclamol and the resulting labeling was determined by liquid scint...

journal_title：Neuroscience

authors： Bardo MT,Hammer RP Jr

更新日期：1991-01-01 00:00:00

abstract：:Peripheral neuropathy represents an important complication of diabetes involving a spectrum of structural, functional and biochemical alterations in peripheral nerves. Recent observations obtained in our laboratory have shown that the levels of neuroactive steroids present in the sciatic nerve of rat raised diabetic b...

journal_title：Neuroscience

authors： Giatti S,Pesaresi M,Cavaletti G,Bianchi R,Carozzi V,Lombardi R,Maschi O,Lauria G,Garcia-Segura LM,Caruso D,Melcangi RC

更新日期：2009-12-01 00:00:00

abstract：:Field recordings of responses to activation of corticostriatal afferents were made in coronally sectioned rat brain slices. Each recording site was categorized according to its medial to lateral and rostral to caudal position to investigate anatomical differences in synaptic plasticity. Individual responses were highl...

journal_title：Neuroscience

authors： Smith R,Musleh W,Akopian G,Buckwalter G,Walsh JP

更新日期：2001-01-01 00:00:00

abstract：:Leptin is well known to be involved in the control of feeding, reproduction and neuroendocrine functions through its action on the hypothalamus. However, leptin receptors are found in brain regions other than the hypothalamus (including the hippocampus and cerebral cortex) suggesting extrahypothalamic functions. We in...

journal_title：Neuroscience

authors： Li XL,Aou S,Oomura Y,Hori N,Fukunaga K,Hori T

更新日期：2002-01-01 00:00:00

abstract：:Adrenergic modulation of glutamatergic spontaneous miniature excitatory postsynaptic currents (mEPSCs) was investigated in mechanically dissociated rat ventromedial hypothalamic (VMH) neurons using a conventional whole-cell patch clamp technique. Noradrenaline (NA) reversibly increased mEPSC frequency without affectin...

journal_title：Neuroscience

authors： Lee JG,Choi IS,Park EJ,Cho JH,Lee MG,Choi BJ,Jang IS

更新日期：2007-02-23 00:00:00

abstract：:In order to develop another selective marker for cholinergic cell bodies and fibres, we have raised a highly specific polyclonal antibody against a peptide derived from the C-terminus of a recently cloned putative vesicular acetylcholine transporter. This antibody recognizes the vesicular acetylcholine transporter pro...

journal_title：Neuroscience

authors： Roghani A,Shirzadi A,Butcher LL,Edwards RH

更新日期：1998-02-01 00:00:00

abstract：:Since the early 90s, the subthalamic nucleus (STN) has started to be the subject of an increasing interest not only in the community of the basal ganglia scientists but also for neurosurgeons and neurologists, thanks to the development of the surgical treatment for Parkinson's disease. The involvement of the STN in co...

journal_title：Neuroscience

authors： Baunez C,Yelnik J,Mallet L

更新日期：2011-12-15 00:00:00

abstract：:Subcutaneous or intracerebroventricular injection of either arginine8-vasopressin or desglycinamide9-arginine8-vasopressin has been shown to facilitate memory, reduce or reverse the effects of amnesic drugs, and maintain tolerance to some effects of ethanol. These actions of vasopressin (and, by inference, of desglyci...

journal_title：Neuroscience

authors： Lança AJ,Wu PH,Jung B,Liu JF,Ng V,Kalant H

更新日期：1999-01-01 00:00:00