Activity-dependent regulation of genes implicated in X-linked non-specific mental retardation.

abstract：:Rapid eye movement sleep decreases between 10 and 30 days postnatally in the rat. The pedunculopontine nucleus is known to modulate waking and rapid eye movement sleep, and pedunculopontine nucleus neurons are thought to be hyperpolarized by noradrenergic input from the locus coeruleus. The goal of the study was to in...

journal_title：Neuroscience

authors： Bay KD,Mamiya K,Good CH,Skinner RD,Garcia-Rill E

更新日期：2006-08-25 00:00:00

abstract：OBJECTIVES:The aim of this study was to investigate whether an objective measure of freezing of gait (FOG) using a validated alternating stepping in place (SIP) task, is related to executive and/or visuospatial cognitive impairment in Parkinson's disease (PD). METHODS:We studied prospectively 30 PD subjects with the U...

journal_title：Neuroscience

authors： Nantel J,McDonald JC,Tan S,Bronte-Stewart H

更新日期：2012-09-27 00:00:00

abstract：:When adult dorsal root ganglion cells are dissociated and maintained in vitro, both the small dark and the large light neurons show increases in the growth-associated protein GAP-43, a membrane phosphoprotein associated with neuronal development and plasticity. Immunoreactivity for GAP-43 appears in the cytoplasm of t...

journal_title：Neuroscience

authors： Woolf CJ,Reynolds ML,Molander C,O'Brien C,Lindsay RM,Benowitz LI

更新日期：1990-01-01 00:00:00

abstract：:There appear to be different relationships between mu-opioid receptor densities and the acute and neuroadaptive mu-opioid agonist-induced responses of the multiple opioid neuronal systems, including important pons/medulla circuits. The recent success in creating mu-opioid receptor knockout mice allows studies of mu-op...

journal_title：Neuroscience

authors： Mizoguchi H,Narita M,Oji DE,Suganuma C,Nagase H,Sora I,Uhl GR,Cheng EY,Tseng LF

更新日期：1999-01-01 00:00:00

abstract：:To better understand the function of the Wnt pathway in the developing telencephalon, we analyzed neocortical development in low density lipoprotein receptor-related protein (LRP) 6 mutants. LRP6 mutant mice are hypomorphic for the canonical Wnt signaling pathway and have hypoplasia of the developing neocortex. While ...

journal_title：Neuroscience

authors： Zhou CJ,Borello U,Rubenstein JL,Pleasure SJ

更新日期：2006-11-03 00:00:00

abstract：:Ovarian hormones regulate pyramidal cell synapse formation and excitability and interneuronal GABAergic tone in the CA1 region of the adult female rat hippocampus. The role of 17beta-estradiol in these effects is complex and appears to involve a subset of hippocampal interneurons, which express different calcium-bindi...

journal_title：Neuroscience

authors： Nakamura NH,McEwen BS

更新日期：2005-01-01 00:00:00

abstract：:Both long-term depression and long-term potentiation have been described at corticostriatal synapses. These long-lasting changes in synaptic strength were classically induced by high-frequency (100 Hz) electrical stimulations of cortical afferents. The purpose of the present study was to test the ability of corticostr...

journal_title：Neuroscience

authors： Charpier S,Mahon S,Deniau JM

更新日期：1999-01-01 00:00:00

abstract：:Synthesis of phosphatidylcholine, the most abundant brain membrane phosphatide, requires three circulating precursors: choline; a pyrimidine (e.g. uridine); and a polyunsaturated fatty acid. Supplementing a choline-containing diet with the uridine source uridine-5'-monophosphate (UMP) or, especially, with UMP plus the...

journal_title：Neuroscience

authors： Cansev M,Wurtman RJ

更新日期：2007-08-24 00:00:00

abstract：:Neurons expressing immunoreactivity to antisera against somatostatin 14 and other somatostatin-related peptides were identified in the striatum of cats and nonhuman primates. In each species, immunoreactive neurons were distributed singly and in small groups in the caudate nucleus, putamen and ventral striatum. A deta...

journal_title：Neuroscience

authors： Chesselet MF,Graybiel AM

更新日期：1986-03-01 00:00:00

abstract：:Acute osmolar loading of cerebrospinal fluid within one lateral ventricle of dogs was examined as a cause of water extraction from the bloodstream and an increase in intracranial pressure. We have shown that a certain amount of (3)H₂O from the bloodstream enters osmotically loaded cerebrospinal fluid significantly fas...

journal_title：Neuroscience

authors： Klarica M,Miše B,Vladić A,Radoš M,Orešković D

更新日期：2013-09-17 00:00:00

abstract：:Sigma-1 receptor (S1R) is a unique pluripotent modulator of living systems and has been reported to be associated with a number of neurological diseases including pathological pain. Intrathecal administration of S1R antagonists attenuates the pain behavior of rodents in both inflammatory and neuropathic pain models. H...

journal_title：Neuroscience

authors： Mavlyutov TA,Duellman T,Kim HT,Epstein ML,Leese C,Davletov BA,Yang J

更新日期：2016-09-07 00:00:00

abstract：:Microtubule-associated protein 1B is a major constituent of the neuronal cytoskeleton during the early stages of development. This protein and its phosphorylated isoform, microtubule-associated protein 1B-P, defined by the monoclonal antibody 1B-P [Boyne L. J. et al. (1995) J. Neurosci. Res. 40, 439-450], are present ...

journal_title：Neuroscience

authors： Ma D,Connors T,Nothias F,Fischer I

更新日期：2000-01-01 00:00:00

abstract：:Free intracellular calcium concentration ([Ca2+]in) was recorded at 22 degrees C by means of Indo-1 or Fura-2 single-cell microfluorometry in cultured dorsal root ganglion neurons obtained from neonatal rats. The resting [Ca2+]in in dorsal root ganglion neurons was 73 +/- 21 nM (mean +/- S.D., n = 94). Fast applicatio...

journal_title：Neuroscience

authors： Usachev Y,Shmigol A,Pronchuk N,Kostyuk P,Verkhratsky A

更新日期：1993-12-01 00:00:00

abstract：:The mechanism of action of conventional antidepressants (e.g. imipramine) has been linked to modulation of central monoamine systems. Substance P (NK1) receptor antagonists may have antidepressant and anxiolytic effects in patients with major depressive disorder and high anxiety but, unlike conventional antidepressant...

journal_title：Neuroscience

authors： Maubach KA,Martin K,Chicchi G,Harrison T,Wheeldon A,Swain CJ,Cumberbatch MJ,Rupniak NM,Seabrook GR

更新日期：2002-01-01 00:00:00

abstract：:The senses of hearing and balance in vertebrates are transduced by hair cells in the inner ear. Hair cells from a wide variety of organisms have been described electrophysiologically but this is the first report of the application of these techniques to the genetically tractable zebrafish model system. Auditory and ve...

journal_title：Neuroscience

authors： Haden M,Einarsson R,Yazejian B

更新日期：2013-09-17 00:00:00

abstract：:In a natural acoustic environment, sound stimuli often occur in a contextual acoustic stream. The aim of the present study was to determine how the frequency tuning of auditory cortical neurons is affected by an acoustic context. A forward masking paradigm was used to determine the frequency receptive fields of rat au...

journal_title：Neuroscience

authors： Peng Y,Sun X,Zhang J

更新日期：2010-09-01 00:00:00

abstract：:Reversal learning is a domain that involves cognitive flexibility and is defined as the ability to rapidly alter established patterns of behavior when confronted with changing circumstances. This function depends critically on the orbitofrontal cortex (OFC) in the prefrontal cortical (PFC) structure, which is among th...

journal_title：Neuroscience

authors： Mizoguchi K,Shoji H,Tanaka Y,Tabira T

更新日期：2010-11-10 00:00:00

abstract：:The dual effect of capsaicin on primary afferent neurons, excitation and stimulation of transmitter release, its dependence on extracellular calcium and its modulation by Ruthenium Red have been investigated in the rabbit ear. Injection of capsaicin into the central artery of the isolated perfused ear with intact neur...

journal_title：Neuroscience

authors： Amann R,Donnerer J,Lembeck F

更新日期：1989-01-01 00:00:00

abstract：:A significant number of postmenopausal women report increased anxiety and vulnerability to stress, which has been linked to decreased secretion of ovarian steroids. Communication between the serotonin system and the corticotropin releasing factor (CRF) system determines stress sensitivity or resilience. This study exa...

journal_title：Neuroscience

authors： Sanchez RL,Reddy AP,Bethea CL

更新日期：2010-12-15 00:00:00

abstract：:Recurring patterns of neural activity, a potential substrate of both information transfer and transformation in cortical networks, have been observed in the intact brain and in brain slices. Do these patterns require the inherent cortical microcircuitry of such preparations or are they a general property of self-organ...

journal_title：Neuroscience

authors： Rolston JD,Wagenaar DA,Potter SM

更新日期：2007-08-10 00:00:00

abstract：:Many behaviorally relevant sounds, including language, are composed of brief, rapid, repetitive acoustic features. Recent studies suggest that abnormalities in producing and understanding spoken language are correlated with abnormal neural responsiveness to such auditory stimuli at higher auditory levels [Tallal et al...

journal_title：Neuroscience

authors： Bartlett EL,Smith PH

更新日期：2002-01-01 00:00:00

abstract：:Astrocytes in the somatosensory ventrobasal (VB) thalamus of rats respond to glutamatergic synaptic input with metabotropic glutamate receptor (mGluR) mediated intracellular calcium ([Ca²⁺](i)) elevations. Astrocytes in the VB thalamus also release the gliotransmitter (GT) glutamate in a Ca²⁺-dependent manner. The tri...

journal_title：Neuroscience

authors： Pirttimaki TM,Parri HR

更新日期：2012-03-15 00:00:00

abstract：:Microglia, the innate immune cells of the brain, regulate brain development through many processes such as synaptic pruning, supporting cell genesis and phagocytosing living and dying cells. There are sex differences in these same developmental processes throughout the brain, thus microglia may contribute to brain sex...

journal_title：Neuroscience

authors： Nelson LH,Peketi P,Lenz KM

更新日期：2021-01-15 00:00:00

abstract：:According to the simulation theory, the internal simulation of a movement (imagined movement, IM) and its execution (actual movement, AM) are based on the same motor representations. The brain uses these representations for controlling action. The specific objective of this study was to investigate the updating proces...

journal_title：Neuroscience

authors： Chabeauti PY,Assaiante C,Vaugoyeau M

更新日期：2012-10-11 00:00:00

abstract：:Cognitive aging affects episodic memory and executive functions, and these vulnerable domains are postulated to be modulated by endogenous and exogenous estrogen exposures. In midlife and late-life women without dementia, estrogen effects on cognition can be examined through associations with concentrations of serum e...

journal_title：Neuroscience

authors： Henderson VW,Popat RA

更新日期：2011-09-15 00:00:00

abstract：:S100A1 and S100B are members of a multigenic family of Ca(2+)-binding proteins of the EF-hand type highly abundant in astrocyte and striated muscle cells that have been implicated in the Ca(2+)-dependent regulation of several intracellular activities including the assembly and disassembly of microtubules and type III ...

journal_title：Neuroscience

authors： Sorci G,Agneletti AL,Donato R

更新日期：2000-01-01 00:00:00

abstract：:The viral transneuronal labeling method was used to examine whether the suprachiasmatic nucleus (SCN) is linked by multisynaptic connections to the medial prefrontal cortex of the rat. In separate experiments, pseudorabies virus (PRV) was injected into one of the three different cytoarchitectonic regions that comprise...

journal_title：Neuroscience

authors： Sylvester CM,Krout KE,Loewy AD

更新日期：2002-01-01 00:00:00

abstract：:Central oxytocin plays an important role in regulating emotionality. The amygdala expresses gonadal steroid-sensitive oxytocin binding sites in both the central and medial sub-nuclei, although the densities markedly differ between these nuclei. These studies examined the in vitro electrophysiological effects of oxytoc...

journal_title：Neuroscience

authors： Terenzi MG,Ingram CD

更新日期：2005-01-01 00:00:00

abstract：:An in vitro slice preparation of combined hippocampus and entorhinal cortex from adult rats was used to study the modalities of generation and propagation, as well as the pharmacological properties of the epileptiform activity induced by the muscarinic agonist pilocarpine (10 microM). Simultaneous field potentials rec...

journal_title：Neuroscience

authors： Nagao T,Alonso A,Avoli M

更新日期：1996-05-01 00:00:00

abstract：:The distribution of different metabotropic glutamate receptors (mGluRs 1a, 1b, 1c, 2/3, 4 and 5) has been compared in the superior colliculus of the rat, cat and ferret using immunohistochemical techniques and light microscopy. We found that although there are differences in labelling patterns between the species, the...

journal_title：Neuroscience

authors： Cirone J,Sharp C,Jeffery G,Salt TE

更新日期：2002-01-01 00:00:00