A newly designed automatic pH-cycling system to simulate daily pH fluctuations.

Abstract:

:The aim of this study was to develop and evaluate an automatic pH-cycling system, which was intended for performing time-lapse analyses of dental caries. Two single-section specimens prepared from each of the five extracted human incisors were studied under a condition of 3- or 9-cycles/day for seven weeks. Increase of mineral loss (delta delta Z) and increase of Ld (delta Ld) were examined and compared at the end of every week during the study. In the 3-cycles/day condition, delta delta Z and delta Ld significantly increased only at Week 7. In the 9-cycles/day condition, delta deltaZ increased significantly from Week 5. delta Ld increased from Week 2, and then there were no further increases for the subsequent five weeks. Based on the results of this study, progression pattern was found to be significantly different between the two conditions. We therefore concluded that the automatic pH-cycling system which we have developed qualified as a model system that simulated the human oral cavity. As such, it could be beneficially employed to clarify the roles of many factors that cause or prevent caries development in human teeth.

journal_name

Dent Mater J

journal_title

Dental materials journal

authors

Matsuda Y,Komatsu H,Murata Y,Tanaka T,Sano H

doi

10.4012/dmj.25.280

subject

Has Abstract

pub_date

2006-06-01 00:00:00

pages

280-5

issue

2

eissn

0287-4547

issn

1881-1361

journal_volume

25

pub_type

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