Genetic potential of interfacial guided osteogenesis in implant devices.

Abstract:

:The purpose of this review is to summarise recent advances in the design and composition of bioactive surface layers of implantabile biomaterials, and thus the genetic potential of osteoprogenitor cells to recognize and respond to these diverse implanted biomaterials. Changes applied to a biomaterial's surface, in general, could improve its biocompatibility, osseointegration and durability properties, which are required for long-term implantation in the living body. In this review, the implant-bone interface was evaluated and interpreted on the basis of osteoblast cell cultures, i.e., on the genetic potential of osteoblasts to express different phenotype markers depending on the type of biomaterials used. The interface formed by in vitro-grown osteoblasts may be used to identify components of the in vivo implant-bone interface. Over the years, a large number of implant systems consisting of many different biomaterials have been introduced in dentistry and orthopaedics. This paper discusses the performance of currently used metals and other biomaterials, by focusing on the events which occur immediately after implantation and on their impact on the bone-implant interface. The review demonstrates that continuous improvements in composition, surface modality and design of implants may benefit osseointegration and clinical longevity of such implants. No load-bearing conditions or clinical status are discussed. Titanium (Ti) and calcium phosphate ceramics are regarded as the most biocompatible synthetic substances known to be used in hard tissue implantation. These biomaterials are osteoconductive, and do not induce ectopic bone formation. Nonetheless, they provide a physical matrix which is suitable for the deposition of new bone and may guide both the growth and extension of the bone. Comparative investigation evaluated that Ti implant systems appear to be apposed by more bone than ceramic systems, although alternatives concerning the type of Ti alloy and bioactive surface layer engineering, generate extremely diverse osseointegration results. Manufacturers have created an extensive range of inorganic or ceramic coatings on Ti implants in order to achieve better bone healing and osteoconduction. Biologically active molecules, added to the implant surface, represent breakthroughs in guided interfacial osteogenesis. This methodology offers an enormous potential of genetic controlling and promoting osteogenesis. The bone growth factors are not fully understood, but most researchers agree that the contact between the bioactive surface layer of the implant and bone is not static but dynamic and that the above factors may maximise the implant osseointegration.

journal_name

Dent Mater J

journal_title

Dental materials journal

authors

Letić-Gavrilović A,Scandurra R,Abe K

doi

10.4012/dmj.19.99

keywords:

subject

Has Abstract

pub_date

2000-06-01 00:00:00

pages

99-132

issue

2

eissn

0287-4547

issn

1881-1361

journal_volume

19

pub_type

杂志文章,评审
  • Relation between attractive force and keeper surface characteristics of iron-neodymium-boron magnetic attachment systems.

    abstract::The purpose of this study was to evaluate the influence of heating, cast bonding, and subsequent polishing procedures on attractive force of magnetic attachments. Two magnetic attachment systems with keepers of different chemical compositions (Hicorexslim 3013, 447J1; Magfit EX400, AUM20) were employed. Keepers examin...

    journal_title:Dental materials journal

    pub_type: 杂志文章

    doi:10.4012/dmj.26.393

    authors: Ohashi N,Koizumi H,Ishikawa Y,Furuchi M,Matsumura H,Tanoue N

    更新日期:2007-05-01 00:00:00

  • Hardness and Young's modulus of transparent dentin associated with aging and carious disease.

    abstract::This study investigated the changes in hardness and Young's modulus of the transparent layer of dentin associated with aging and the carious process. Eighteen extracted human molars with or without coronal caries were used in this study. The normal teeth were divided into two groups by age, and the carious teeth were ...

    journal_title:Dental materials journal

    pub_type: 杂志文章

    doi:10.4012/dmj.24.648

    authors: Zheng L,Nakajima M,Higashi T,Foxton RM,Tagami J

    更新日期:2005-12-01 00:00:00

  • Effect of sodium hypochlorite contamination on microhardness of dental core build-up materials.

    abstract::This study aimed to determine the influence of sodium hypochlorite (NaOCl) contamination on the microhardness of build-up composites. Fifty-two samples, from each of three build-up materials (LuxaCore Dual, MultiCore flow and Rebilda DC) were prepared. Half of the samples from each material were stored in physiologic ...

    journal_title:Dental materials journal

    pub_type: 杂志文章

    doi:10.4012/dmj.2010-007

    authors: Wegehaupt FJ,Betschart J,Attin T

    更新日期:2010-08-01 00:00:00

  • Predicting in vivo failure of rotary nickel-titanium endodontic instruments under cyclic fatigue.

    abstract::The aim of this study was to examine the lifespan or number of cycles to failure of tapered rotary nickel-titanium (Ni-Ti) endodontic instruments. Simulated root canals with different curvatures were used to determine a relation between canal curvature and instrument lifespan. Using a novel mathematical model for the ...

    journal_title:Dental materials journal

    pub_type: 杂志文章

    doi:10.4012/dmj.2011-254

    authors: Stojanac I,Drobac M,Petrovic L,Atanackovic T

    更新日期:2012-01-01 00:00:00

  • Swelling/deswelling mechanism of calcium alginate gel in aqueous solutions.

    abstract::To elucidate the mechanism of dimensional changes in alginate impression in solutions, the relationship between the ion concentrations in three types of solutions (nonelectrolyte and monovalent and divalent metallic salts) and change in gel volume was examined. The gel in the monovalent metallic salt solution expanded...

    journal_title:Dental materials journal

    pub_type: 杂志文章

    doi:10.4012/dmj.19.396

    authors: Saitoh S,Araki Y,Kon R,Katsura H,Taira M

    更新日期:2000-12-01 00:00:00

  • An ultrastructural analysis of the prototype single-step adhesive applied on enamel and dentin surfaces.

    abstract::A new type of self-etching agent, the single-step adhesive, was developed. The purpose of this study was to investigate the difference in the ultrastructural features of enamel and dentin surfaces following application of the prototype single-step adhesive (EXM618, 3M, MN, USA). Extracted caries-free human premolars w...

    journal_title:Dental materials journal

    pub_type: 杂志文章

    doi:10.4012/dmj.23.321

    authors: Han L,Cruz E,Fukushima M,Okamoto A,Okiji T

    更新日期:2004-09-01 00:00:00

  • Influence of three specimen fixation modes on the micro-tensile bond strength of adhesives to dentin.

    abstract::The aim of this study was to investigate in how far the way the specimen is fixed to the testing device influences the micro-tensile bond strength of adhesives to dentin. Compared to a flat jig, a notched jig enables the specimen to be aligned easier and more accurately perpendicular to the interface, thereby concentr...

    journal_title:Dental materials journal

    pub_type: 杂志文章

    doi:10.4012/dmj.26.694

    authors: Poitevin A,De Munck J,Van Landuyt K,Coutinho E,Peumans M,Lambrechts P,Van Meerbeek B

    更新日期:2007-09-01 00:00:00

  • Fracture force for veneered materials on restorations measured by torsion testing.

    abstract::The torsional fracture strength at the interface between a base plate and veneering material was evaluated for three kinds of veneered restoration: porcelain fused to zirconia (PFZ), porcelain fused to metal (PFM), and composite resin veneered metal (CRVM). The metal and zirconia base plate (30×4×0.4 mm) were prepared...

    journal_title:Dental materials journal

    pub_type: 杂志文章

    doi:10.4012/dmj.2016-432

    authors: Watanabe F,Seto M,Ueda K,Ozawa M

    更新日期:2018-07-29 00:00:00

  • Effect of surface preparation on the bond strength of heat-polymerized denture base resin to commercially pure titanium and cobalt-chromium alloy.

    abstract::The aim of this study was to investigate the bond durability of heat-polymerized denture base resin to cast CP Ti and Co-Cr alloy. The alloy specimens were divided into five groups: 1) airborne-particle abraded with 50 µm alumina (SAND), 2) Rocatec tribochemical silica coating system (RO), 3) air-abraded followed by a...

    journal_title:Dental materials journal

    pub_type: 杂志文章,随机对照试验

    doi:10.4012/dmj.2010-089

    authors: Kawaguchi T,Shimizu H,Lassila LV,Vallittu PK,Takahashi Y

    更新日期:2011-01-01 00:00:00

  • Degradation of dental ZrO2-based materials after hydrothermal fatigue. Part I: XRD, XRF, and FESEM analyses.

    abstract::The aim was to investigate the effect of simulated low-temperature degradation (s-LTD) and hydrothermal fatigue on the degradation of three ZrO(2)-based dental materials. Lava, IPS, and NanoZr discs were randomly assigned to (1) Control-Storage in distilled water at 37°C; (2) Aging at 134°C for 5 h (s-LTD); (3) Thermo...

    journal_title:Dental materials journal

    pub_type: 杂志文章

    doi:10.4012/dmj.2011-216

    authors: Perdigão J,Pinto AM,Monteiro RC,Braz Fernandes FM,Laranjeira P,Veiga JP

    更新日期:2012-01-01 00:00:00

  • A review of our development of dental adhesives--effects of radical polymerization initiators and adhesive monomers on adhesion.

    abstract::This paper reviews the development of dental adhesives by collating information of related studies from original scientific papers, reviews, and patent literatures. Through our development, novel radical polymerization initiators, adhesive monomers, and microcapsules were synthesized, and their effects on adhesion wer...

    journal_title:Dental materials journal

    pub_type: 杂志文章,评审

    doi:10.4012/dmj.2009-057

    authors: Ikemura K,Endo T

    更新日期:2010-03-01 00:00:00

  • Microtensile bond strength of a newly developed resin cement to dentin.

    abstract::The purpose of this study was to evaluate the microtensile bond strength (µTBS) of a newly developed resin cement, ECD-89 (ECD, Tokuyama Dental, Tokyo, Japan) to dentin and to observe the interfacial micromorphology by comparing with two commercial resin cements, Multilink Automix (MA, Ivoclar Vivadent AG, Schaan, Lie...

    journal_title:Dental materials journal

    pub_type: 杂志文章

    doi:10.4012/dmj.2014-122

    authors: Kawano S,Fu J,Saikaew P,Chowdhury AA,Fukuzawa N,Kadowaki Y,Kakuda S,Hoshika S,Nakaoki Y,Ikeda T,Tanaka T,Sano H

    更新日期:2015-01-01 00:00:00

  • Influence of a propolis-based irrigant solution on gap formation and bond strength of posts bonded to root canal dentin using different resin cements.

    abstract::This study evaluated the influence of an aqueous propolis-based solution (PROP) on gap formation and bond strength of posts bonded to root canal dentin using resin cements. Endodontically-treated bovine incisors received different irrigation protocols: 1) 2.5% sodium hypochlorite (NaOCl)/17% EDTA/NaOCl; 2) saline solu...

    journal_title:Dental materials journal

    pub_type: 杂志文章

    doi:10.4012/dmj.2019-111

    authors: Matochek MHM,Tomaz PLS,Oliveira TS,Polassi MR,Alonso RCB,Scremin FM,Sauro S,Marcucci MC,D'Alpino PHP

    更新日期:2020-06-05 00:00:00

  • Zirconia ceramics, their contrast ratio and grain size depending on sintering parameters.

    abstract::This study investigated the contrast ratio and grain size depending on sintering parameters of twelve different zirconia materials and compared with glass-ceramic (N=156, n=12 per group). Contrast ratio of all ceramics was measured using a spectrophotometer according to ISO 2471: 2008. Grain sizes of zirconia were det...

    journal_title:Dental materials journal

    pub_type: 杂志文章

    doi:10.4012/dmj.2014-056

    authors: Stawarczyk B,Emslander A,Roos M,Sener B,Noack F,Keul C

    更新日期:2014-01-01 00:00:00

  • Comparative analysis of bovine serum albumin adsorption onto octacalcium phosphate crystals prepared using different methods.

    abstract::This study compared bovine serum albumin (BSA) adsorption onto octacalcium phosphate (OCP) materials prepared from two wet preparations in the absence (w-OCP) and presence (c-OCP) of gelatin. Raman spectroscopy was used to analyze the BSA adsorption onto OCPs in a 150 mM Tris-HCl buffer containing 0.5 mM calcium and i...

    journal_title:Dental materials journal

    pub_type: 杂志文章

    doi:10.4012/dmj.2019-250

    authors: Tsuchiya K,Hamai R,Sakai S,Suzuki O

    更新日期:2020-09-29 00:00:00

  • Anti-demineralization characteristics of surface pre-reacted glass-ionomer (S-PRG) filler-containing varnishes.

    abstract::This study investigated the anti-demineralization effects of surface pre-reacted glass-ionomer (S-PRG) filler-containing varnishes. Thirty-five bovine root specimens were divided into five treatment groups, with seven specimens each coated with 1) MI varnish (MIV), 2) F varnish (FV), 3) PRG varnish I (PV), 4) PRG varn...

    journal_title:Dental materials journal

    pub_type: 杂志文章

    doi:10.4012/dmj.2019-396

    authors: Shiiya T,Kataoka A,Tomiyama K,Fujino F,Mukai Y

    更新日期:2020-11-11 00:00:00

  • Kinetic polymerization behavior of fluorinated monomers for dental use.

    abstract::The kinetic polymerization behavior of 2,2,2-trifluoroethyl methacrylate (TFEMA), 1,1,1,3,3,3-hexafluoroisopropyl methacrylate (HFIPMA), 2,2,2-trifluoroethyl acrylate (TFEA) and 1,1,1,3,3,3-hexafluoroisopropyl acrylate (HFIPA) was determined by isothermal differential scanning calorimetry (DSC) and high-performance li...

    journal_title:Dental materials journal

    pub_type: 杂志文章

    doi:10.4012/dmj.2010-054

    authors: Kadoma Y

    更新日期:2010-10-01 00:00:00

  • Initial attachment of human oral keratinocytes cultured on zirconia or titanium.

    abstract::Initial attachment of human oral keratinocytes (HOKs) cultured on mirror-surfaced commercially pure titanium (Ti) or yttria-stabilized tetragonal zirconia polycrystals (TZP) was investigated. Numbers of viable attached HOKs, their mRNAs and proteins expression of laminin γ2 and integrin β4 were evaluated using the WST...

    journal_title:Dental materials journal

    pub_type: 杂志文章

    doi:10.4012/dmj.2011-189

    authors: Kimura Y,Matsuzaka K,Yoshinari M,Inoue T

    更新日期:2012-01-01 00:00:00

  • Surface effects after a combination of dental bleaching and enamel microabrasion: An in vitro and in situ study.

    abstract::This study evaluated the effects of combining enamel microabrasion and dental bleaching on the physical properties of enamel, using in vitro and in situ conditions and evaluating surface roughness, enamel microhardness and scanning electron microscopy images. One hundred sound bovine teeth were sectioned and cut into ...

    journal_title:Dental materials journal

    pub_type: 杂志文章

    doi:10.4012/dmj.2014-334

    authors: Franco LM,Machado LS,Salomão FM,Dos Santos PH,Briso AL,Sundfeld RH

    更新日期:2016-01-01 00:00:00

  • Analysis of abutment tooth movement utilizing mandibular kinesiography (MKG). Part 2. Effects of clasp design in unilateral free-end denture.

    abstract::The three-dimensional dynamic movement of the abutment tooth was successfully analyzed on a simulation model utilizing the mandibular kinesiography. When the unilateral free-end denture retained by the RPA, RPI or Aker's clasp was subjected to various directions of loads, the abutment tooth was inclined mainly by the ...

    journal_title:Dental materials journal

    pub_type: 杂志文章

    doi:10.4012/dmj.8.56

    authors: Morikawa M,Masumi S,Kido H,Toyoda S,Kozono Y

    更新日期:1989-06-01 00:00:00

  • Shear bond strength of tooth-colored indirect restorations bonded to mid-coronal and cervical dentin.

    abstract::To investigate the bonding of tooth-colored indirect restorations to cervical dentin, shear bond strengths of bonded resin inlays to cervical dentin and mid-coronal dentin were investigated and compared. Indirectly fabricated composite inlays (Estenia) were cemented with a dual-cured resin cement (Panavia Fluoro Cemen...

    journal_title:Dental materials journal

    pub_type: 杂志文章

    doi:10.4012/dmj.25.7

    authors: Shimada Y,Sattabanasuk V,Sadr A,Yuan Y,He Z,Tagami J

    更新日期:2006-03-01 00:00:00

  • The extent of polymerization of Class II light-cured composite resin restorations; effects of incremental placement technique, exposure time and heating for resin inlays.

    abstract::The extent of polymerization of light-cured composite resins cured in relatively large class II cavities was estimated by measuring Knoop hardness on sectioned surfaces of resin restorations. The influences of the incremental placement technique, exposure time, and post-curing of resin inlay on the extent of polymeriz...

    journal_title:Dental materials journal

    pub_type: 杂志文章

    doi:10.4012/dmj.12.159

    authors: Hirabayashi S,Hood JA,Hirasawa T

    更新日期:1993-12-01 00:00:00

  • Surface properties and biocompatibility of acid-etched titanium.

    abstract::The purpose of this study was to evaluate the effects of acid-etched titanium on the biological responses of osteoblast-like MC3T3-E1 cells. Four types of treatments (polishing, sandblasting, concentrated H2SO4 etching, and concentrated H2SO4 etching with vacuum firing) were carried out on the surfaces of commercially...

    journal_title:Dental materials journal

    pub_type: 杂志文章

    doi:10.4012/dmj.27.415

    authors: Iwaya Y,Machigashira M,Kanbara K,Miyamoto M,Noguchi K,Izumi Y,Ban S

    更新日期:2008-05-01 00:00:00

  • Antimicrobial and antibiofilm activities of MTA supplemented with bismuth lipophilic nanoparticles.

    abstract::The objective of this work was to determine the antimicrobial and antibiofilm properties of mineral trioxide aggregate (MTA) supplemented with bismuth lipophilic nanoparticles (BisBAL NPs). The antimicrobial activity of the composite MTA-BisBAL NPs was determined by the disk diffusion assay, while antibiofilm activity...

    journal_title:Dental materials journal

    pub_type: 杂志文章

    doi:10.4012/dmj.2016-259

    authors: Hernandez-Delgadillo R,Del Angel-Mosqueda C,Solís-Soto JM,Munguia-Moreno S,Pineda-Aguilar N,Sánchez-Nájera RI,Chellam S,Cabral-Romero C

    更新日期:2017-07-26 00:00:00

  • Effects of attrition, prior acid-etching, and cyclic loading on the bond strength of a self-etching adhesive system to dentin.

    abstract::The purpose of this study was to evaluate the effects of dentin attrition, phosphoric acid etching, and cyclic loading on the microtensile bond strength (microTBS) of a self-etching adhesive system to dentin. Flat dentin surfaces of human molars were assigned to eight experimental groups based on those with or without...

    journal_title:Dental materials journal

    pub_type: 杂志文章,随机对照试验

    doi:10.4012/dmj.28.197

    authors: Shinkai K,Ebihara T,Shirono M,Seki H,Wakaki S,Suzuki M,Suzuki S,Katoh Y

    更新日期:2009-03-01 00:00:00

  • Antibacterial activity of composite resin with glass-ionomer filler particles.

    abstract::The purpose of this study was to examine the antibacterial activity of composite resin with glass-ionomer filler particles versus that of contemporary commercial composite resins. Three composite resins were used: Beautifil II (containing S-PRG filler), Clearfil AP-X, and Filtek Z250. Resin blocks were bonded to maxil...

    journal_title:Dental materials journal

    pub_type: 杂志文章,随机对照试验

    doi:10.4012/dmj.2009-050

    authors: Saku S,Kotake H,Scougall-Vilchis RJ,Ohashi S,Hotta M,Horiuchi S,Hamada K,Asaoka K,Tanaka E,Yamamoto K

    更新日期:2010-03-01 00:00:00

  • Ceramic bonding strength of Au-1.6 wt% Ti alloy.

    abstract::The aim of this investigation was to evaluate the metal-ceramic bonding of Au-1.6 wt% Ti alloy. Therefore, the coefficient of thermal expansion, modulus of elasticity, ceramic bonding strength, and hardness of Au-1.6 wt% Ti alloy were measured. The metal-ceramic interface was observed by EPMA to investigate its bondin...

    journal_title:Dental materials journal

    pub_type: 杂志文章

    doi:10.4012/dmj.24.268

    authors: Ito M,Kikuchi M,Okuno O,Kimura K

    更新日期:2005-06-01 00:00:00

  • Possible segregation caused by centrifugal titanium casting.

    abstract::The possibility of the segregation under solidification process using a centrifugal casting machine was investigated using an electron probe microanalyzer with elemental distribution map, line analysis and quantitative analysis. When a very small quantity of platinum was added to local molten titanium during the casti...

    journal_title:Dental materials journal

    pub_type: 杂志文章

    doi:10.4012/dmj.15.212

    authors: Watanabe K,Okawa S,Kanatani M,Nakano S,Miyakawa O,Kobayashi M

    更新日期:1996-12-01 00:00:00

  • Effect of monomer structure on the mechanical properties of light-cured composite resins.

    abstract::The effects of monomer structure on the mechanical properties of visible light-cured composite resins based on the seven types of aromatic dimethacrylates were investigated. The results of this study suggested that the mechanical properties of the composite resins were dependent upon the chemical structure of the dime...

    journal_title:Dental materials journal

    pub_type: 杂志文章

    doi:10.4012/dmj.8.40

    authors: Kawaguchi M,Fukushima T,Horibe T

    更新日期:1989-06-01 00:00:00

  • Micro-shear bond strength of adhesive resins to enamel at different relative humidity conditions.

    abstract::This study tested whether exhaled humid conditions would affect the adhesion of etch-and-rinse, two-step and one-step self-etch adhesive resins to enamel. Enamel surfaces of human maxillary anterior teeth (N=240, n=20) were exposed to four humid conditions (H1: 63-68%, H2: 73-78%, H3: 93-98%, H4: 36-45% RH) during bon...

    journal_title:Dental materials journal

    pub_type: 杂志文章

    doi:10.4012/dmj.2012-200

    authors: Bavbek AB,Demir E,Goktas B,Ozcopur B,Behram B,Eskitascioglu G,Ozcan M

    更新日期:2013-01-01 00:00:00