Phosphorylation of non-histone proteins in the regulation of chromosome structure and function.

abstract：:Human population is facing a revolutionary change in the demographic structure with an increasing number of elderly people requiring an unmet need to ensure a smooth aging process and dental care is certainly an important aspect that has to be considered. To date, dentistry has been conservative and the need of transf...

journal_title：Journal of cellular physiology

authors： Monti M,Graziano A,Rizzo S,Perotti C,Del Fante C,d'Aquino R,Redi CA,Rodriguez Y Baena R

更新日期：2017-03-01 00:00:00

abstract：:Neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), and Huntington's disease (HD), are incurable diseases characterized by progressive loss of cognitive or motor function, which construct a serious threat to the life quality of aging populations and their life spans. Apelin is an ...

journal_title：Journal of cellular physiology

authors： Luo H,Han L,Xu J

更新日期：2020-02-01 00:00:00

abstract：:Chemotherapy resistance is the major issue of choriocarcinoma. Apoptosis always is the ultimate outcome of chemotherapeutic drugs, which considered one of the reasons of resistance. We investigated the role of STAT3/NFIL3 signaling-inhibited apoptosis in chemotherapy resistance and whether Raddeanin A (RA) could be a ...

journal_title：Journal of cellular physiology

authors： Peng Z,Zhang C,Zhou W,Wu C,Zhang Y

更新日期：2018-07-01 00:00:00

abstract：:Protein sorting through vesicular compartments is highly regulated to maintain the integrity and signaling of intracellular organelles in eukaryotic cells. Sorting Nexin-2 (SNX2) is involved in protein sorting in the trans-Golgi network, endosome, and/or lysosome compartments, with loss of function leading to defect i...

journal_title：Journal of cellular physiology

authors： Abdul-Ghani M,Hartman KL,Ngsee JK

更新日期：2005-07-01 00:00:00

abstract：:It has been established that syndecan-1 is an important modulator of events relevant to acute tissue repair and chronic injury responses. The current studies were designed to examine syndecan-1 expression during atherosclerotic lesion formation and whether angiotensin II influences syndecan-1 expression in macrophages...

journal_title：Journal of cellular physiology

authors： Wang W,Haller CA,Wen J,Wang P,Chaikof EL

更新日期：2008-03-01 00:00:00

abstract：:Although glucocorticoids strongly affect numerous biological processes including cell growth, development, and homeostasis, their effects on migration of human mesenchymal stem cells (hMSCs) are unclear. Therefore, we investigated the role of dexamethasone (DEX) and its related signaling pathways on migration of hMSCs...

journal_title：Journal of cellular physiology

authors： Yun SP,Ryu JM,Han HJ

更新日期：2011-03-01 00:00:00

abstract：:Transforming growth factor beta type 1 (TGF-beta 1) was reacted with NHS-biotin to yield a derivative of TGF-beta 1 which was biotinylated on lysine residues. The biotinylated form of TGF-beta 1 was separated from the unreacted material by reverse phase chromatography. In three separate bioassays, the derivatized pept...

journal_title：Journal of cellular physiology

authors： Newman W,Beall LD,Bertolini DR,Cone JL

更新日期：1989-10-01 00:00:00

abstract：:We present evidence that extends our earlier preliminary report on the stimulatory effect of saline washes on confluent cells in culture (Lacey et al., '77). That work suggested that an inhibitory substance was being removed by the washes. The present work suggests that the inhibitor is in the 10,000-30,000 MW range, ...

journal_title：Journal of cellular physiology

authors： Strobel-Stevens JD,Lacey JC Jr

更新日期：1981-02-01 00:00:00

abstract：:Inflammatory bowel disease (IBD), as a chronic and recurrent inflammatory disorder, is caused by a dysregulated and aberrant immune response to exposed environmental factors in genetically susceptible individuals. Despite huge efforts in determining the molecular pathogenesis of IBD, an increasing worldwide incidence ...

journal_title：Journal of cellular physiology

authors： Moein S,Vaghari-Tabari M,Qujeq D,Majidinia M,Nabavi SM,Yousefi B

更新日期：2019-04-01 00:00:00

abstract：:The INI1 gene, which encodes a functionally uncharacterized protein component of the hSWI/SNF chromatin remodeling complex, is often mutated or deleted in malignant rhabdoid tumor (MRT). Two isoforms of INI1, that differ by the variable inclusion of nine amino acids, potentially are produced by differential RNA splici...

journal_title：Journal of cellular physiology

authors： Reincke BS,Rosson GB,Oswald BW,Wright CF

更新日期：2003-03-01 00:00:00

abstract：:The development of resistance accounts for therapy failure in the majority of advanced cases of neuroblastoma in children. A new transplantable murine C-1300 neuroblastoma cell line was developed in vitro, by repeated exposure of a sensitive cell line to increasing, but sublethal, doses of Homoharringtonine (HHT). The...

journal_title：Journal of cellular physiology

authors： Tebbi CK,Chervinsky D,Baker RM

更新日期：1991-09-01 00:00:00

abstract：:Pancreatic cancer is a common malignant digestive disease. Epidemiological and clinical studies have demonstrated that pancreatic cancer is closely related to diabetes mellitus. Diabetic patients are more likely to develop pancreatic cancer, which is linked with poor outcomes. Pancreatic cancer is complicated with abn...

journal_title：Journal of cellular physiology

authors： Ma X,Cui Z,Du Z,Lin H

更新日期：2020-09-01 00:00:00

abstract：:Tumor progression is characterized by loss of cell adhesion and increase of invasion and metastasis. The cell adhesion molecule E-cadherin is frequently down-regulated or mutated in tumors. In addition to down-regulation of cell adhesion, degradation of the extracellular matrix by matrix metalloproteinases is necessar...

journal_title：Journal of cellular physiology

authors： Fuchs M,Hermannstädter C,Specht K,Knyazev P,Ullrich A,Rosivatz E,Busch R,Hutzler P,Höfler H,Luber B

更新日期：2005-03-01 00:00:00

abstract：:Glutathione S-transferases (GSTs) are enzymes that are involved in the detoxification of harmful electrophilic endogenous and exogenous compounds by conjugating with glutathione (GSH). The liver fluke GSTs have multifunctional roles in the host-parasite interaction, such as general detoxification and bile acid sequest...

journal_title：Journal of cellular physiology

authors： Kalita J,Shukla R,Tripathi T

更新日期：2019-04-01 00:00:00

abstract：:Thrombin is known to evoke numerous inflammatory and proliferative responses in a wide variety of its target cells. Recent studies have demonstrated morphoregulatory and mitogenic effects of thrombin on astroglial cells (astrocytes). The present study deals with thrombin-induced activation of mitogen-activated protein...

journal_title：Journal of cellular physiology

authors： Bhat NR,Zhang P,Hogan EL

更新日期：1995-11-01 00:00:00

abstract：:Keratin intermediate filaments play an important role in maintaining the integrity of the skin structure. Understanding the importance of this subject is possible with the investigation of keratin defects in epidermolysis bullosa simplex (EBS). Nowadays, in addition to clinical criteria, new molecular diagnostic metho...

journal_title：Journal of cellular physiology

authors： Khani P,Ghazi F,Zekri A,Nasri F,Behrangi E,Aghdam AM,Mirzaei H

更新日期：2018-01-01 00:00:00

abstract：:Shear stress secondary to increased pulmonary blood flow (PBF) is elevated in some children born with congenital cardiac abnormalities. However, the majority of these patients do not develop pulmonary edema, despite high levels of permeability inducing factors. Previous studies have suggested that laminar fluid shear ...

journal_title：Journal of cellular physiology

authors： Gross CM,Aggarwal S,Kumar S,Tian J,Kasa A,Bogatcheva N,Datar SA,Verin AD,Fineman JR,Black SM

更新日期：2014-11-01 00:00:00

abstract：:An artificial wound in a confluent monolayer of human keratinocyte HaCaT cells or mouse embryo fibroblast Swiss NIH 3T3 cells was used to analyze the effects of the nitric oxide (NO) chemical donor, S-nitroso-N-acetylpenicillamine (SNAP). SNAP exposure promoted an enhanced rate of wound closure and accelerated motilit...

journal_title：Journal of cellular physiology

authors： La Torre C,Cinque B,Lombardi F,Miconi G,Palumbo P,Evtoski Z,Placidi G,Fanini D,Cimini AM,Benedetti E,Giuliani M,Cifone MG

更新日期：2016-10-01 00:00:00

abstract：:Using rapid kinetic techniques, we have determined the kinetics of zero-trans influx and equilibrium exchange of adenosine, and its uptake and in situ phosphorylation at 25 degrees C in human erythrocytes which were pretreated with 2'-deoxycoformycin to inhibit deamination of adenosine. Both the Km and Vmax for adenos...

journal_title：Journal of cellular physiology

authors： Plagemann PG,Wohlhueter RM,Kraupp M

更新日期：1985-11-01 00:00:00

abstract：:Regulation of lipid synthesis from acetate in human diploid fibroblast cultures has been studied at various passage levels and at different stages of cell growth. When cultures were transferred to lipid free medium, a stimulation of [14C]acetate incorporation into lipid occurred within three to six hours after removal...

journal_title：Journal of cellular physiology

authors： Howard BV,Howard WJ,Kefalides NA

更新日期：1976-10-01 00:00:00

abstract：:The polyphenolic compounds curcumin and quercetin increased sensitivity of ovarian cancer cells (CAOV3 and SKOV3) to cisplatin. The effect was obtained when the compounds were added simultaneously with cisplatin, as well as when they were added 24 h before. High serum levels of certain cytokines, for example interleuk...

journal_title：Journal of cellular physiology

authors： Chan MM,Fong D,Soprano KJ,Holmes WF,Heverling H

更新日期：2003-01-01 00:00:00

abstract：:Binge drinking is associated with increased cardiac autophagy, and often triggers heart injury. Given the essential role of autophagy in various cardiac diseases, this study was designed to investigate the role of autophagy in ethanol-induced cardiac injury and the underlying mechanism. Our study showed that ethanol e...

journal_title：Journal of cellular physiology

authors： Zhu Z,Huang Y,Lv L,Tao Y,Shao M,Zhao C,Xue M,Sun J,Niu C,Wang Y,Kim S,Cong W,Mao W,Jin L

更新日期：2018-02-01 00:00:00

abstract：:Biosynthesis of selenium-containing proteins requires insertion of the unusual amino acid selenocysteine by alternative translation of a UGA codon, which ordinarily serves as a stop codon. In eukaryotes, selenoprotein translation depends upon one or more selenocysteine insertion sequence (SECIS) elements located in th...

journal_title：Journal of cellular physiology

authors： Shen Q,Fan L,Newburger PE

更新日期：2006-06-01 00:00:00

abstract：:Baculoviral IAP repeat containing 5 (BIRC5) gene encodes the important protein as survivin, a multifunctional protein, which is involved in cellular and molecular networks, progression of cell cycle, homeostasis, developmental morphogenesis, and apoptosis. The proximal BIRC5 promoter possesses specific binding sites f...

journal_title：Journal of cellular physiology

authors： Pahlavan Y,Kahroba H,Samadi N,Karimi A,Ansarin K,Khabbazi A

更新日期：2019-11-01 00:00:00

abstract：:Expression of plasminogen activator inhibitor type-1 (PAI-1), a member of the SERPIN gene family that functions to regulate the plasmin-based pericellular proteolytic cascade, is growth state-regulated in normal rat kidney (NRK) cells (Ryan and Higgins, 1990, J. Cell. Physiol., 155:376-384; Ryan et al., 1996, Biochem....

journal_title：Journal of cellular physiology

authors： Kutz SM,Nickey SA,White LA,Higgins PJ

更新日期：1997-01-01 00:00:00

abstract：:Human neutrophils labeled with chlortetracycline (CTC), commonly used as a probe of membrane-bound calcium, release lysosomal enzymes and exhibit a rapid decrease in fluorescence when exposed to the chemotactic peptide fMet-Leu-Phe or the lectin Con A. This decrease has been attributed to the release of calcium from a...

journal_title：Journal of cellular physiology

authors： Smolen JE,Noble P,Freed R,Weissmann G

更新日期：1983-12-01 00:00:00

abstract：:Osteoporosis, arthritis, Peget's disease, bone tumor, periprosthetic joint infection, and periprosthetic loosening have a common characteristic of osteolysis, which is characterized by the enhanced osteoclastic bone resorptive function. At present, the treatment target of these diseases is to interfere with osteoclast...

journal_title：Journal of cellular physiology

authors： Fu F,Shao S,Wang Z,Song F,Lin X,Ding J,Li C,Wu Z,Li K,Xiao Y,Su Y,Zhao J,Liu Q,Xu J

更新日期：2019-07-01 00:00:00

abstract：:Epithelial-mesenchymal transition (EMT), via activation of Wnt signaling, is prevailing in embryogenesis, but postnatally it only occurs in pathological processes, such as in tissue fibrosis and tumor metastasis. Our prior studies led us to speculate that EMT might be involved in the loss of limbal epithelial stem cel...

journal_title：Journal of cellular physiology

authors： Kawakita T,Espana EM,Higa K,Kato N,Li W,Tseng SC

更新日期：2013-01-01 00:00:00

abstract：:Nonalcoholic fatty liver disease (NAFLD) is prevalent chronic liver diseases with unknown mechanism and no curative treatment. Hepatokines have demonstrated importance in NAFLD but, role of selenoprotein P (SeP) in NAFLD is unknown. A total of 79 patients with NAFLD and 79 healthy controls were included in this case-c...

journal_title：Journal of cellular physiology

authors： Chen Y,He X,Chen X,Li Y,Ke Y

更新日期：2020-10-22 00:00:00

abstract：:The SV40 transformed murine macrophage cell line, BAC1, proliferates in response to the colony stimulating factor, CSF-1 (Schwarzbaum et al., J. Immunol., 132:1158, 1984). In order to obtain a cell line suitable for biochemical and genetic studies of CSF-1 signal transduction, clones of BAC1 were established. Clones r...

journal_title：Journal of cellular physiology

authors： Morgan C,Pollard JW,Stanley ER

更新日期：1987-03-01 00:00:00