Further evidence for an inhibitor of proliferation elaborated by normal human fibroblasts in culture: partial characterization of the inhibitor.

Abstract:

:We present evidence that extends our earlier preliminary report on the stimulatory effect of saline washes on confluent cells in culture (Lacey et al., '77). That work suggested that an inhibitory substance was being removed by the washes. The present work suggests that the inhibitor is in the 10,000-30,000 MW range, is reversibly bound, is cationic and is also a protease inhibitor. It is heat stable, but is apparently degraded with time in our experimental systems.

journal_name

J Cell Physiol

authors

Strobel-Stevens JD,Lacey JC Jr

doi

10.1002/jcp.1041060205

subject

Has Abstract

pub_date

1981-02-01 00:00:00

pages

201-7

issue

2

eissn

0021-9541

issn

1097-4652

journal_volume

106

pub_type

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