Abstract:
:Aquaporins are involved in the maintenance of ionic and osmotic balance in the central nervous system and in the eye. Whereas the expression of aquaporin-9 immunoreactivity in the brain has been described for catecholaminergic neurons and glial cells, the expression of aquaporin-9 in the neural retina is unclear. We examined the distribution of aquaporin-1 and -9 immunoreactivities in retinas of the rat. Aquaporin-9 immunoreactivity was expressed exclusively by tyrosine hydroxylase (TH) positive amacrine cells, while aquaporin-1 immunoreactivity was expressed by photoreceptor cells and by TH negative amacrine cells. The staining pattern of aquaporin-9 did not change up to 4 weeks after pressure-induced transient retinal ischemia. It is concluded that catecholaminergic, putatively dopaminergic, amacrine cells of the retina express aquaporin-9.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Iandiev I,Biedermann B,Reichenbach A,Wiedemann P,Bringmann Adoi
10.1016/j.neulet.2006.01.010keywords:
subject
Has Abstractpub_date
2006-05-08 00:00:00pages
264-7issue
3eissn
0304-3940issn
1872-7972pii
S0304-3940(06)00022-Xjournal_volume
398pub_type
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