Abstract：
:Continuum-level finite element (FE) models became standard computational tools for the evaluation of bone mechanical behavior from in vivo computed tomography scans. Such scans do not account for the anisotropy of the bone. Instead, local mechanical properties in the continuum-level FE models are assumed isotropic and are derived from bone density, using statistical relationships. Micro-FE models, on the other hand, incorporate the anisotropic structure in detail. This study aimed to quantify the effects of assumed isotropy, by comparing continuum-level voxel models of a healthy and a severely osteoporotic proximal femur with recently analyzed micro-FE models of the same bones. The micro-model element size was coarsened to generate continuum FE models with two different element sizes (0.64 and 3.04 mm) and two different density-modulus relationships found in the literature for wet and ash density. All FE models were subjected to the same boundary conditions that simulated a fall to the side, and the stress and strain distributions, model stiffness and yield load were compared. The results indicated that the stress and strain distributions could be reproduced well with the continuum models. The smallest differences between the continuum-level model and micro-level model predictions of the stiffness and yield load were obtained with the coarsest element size. Better results were obtained for both continuum-element sizes when isotropic moduli were based on ash density rather than wet density.
journal_name
J Biomechjournal_title
Journal of biomechanicsauthors
Verhulp E,van Rietbergen B,Huiskes Rdoi
10.1016/j.jbiomech.2005.10.027keywords:
subject
Has Abstractpub_date
2006-01-01 00:00:00pages
2951-7issue
16eissn
0021-9290issn
1873-2380pii
S0021-9290(05)00486-0journal_volume
39pub_type
杂志文章abstract：:The aim of this study was to investigate the prevalence of abnormal knee biomechanical patterns in 40 patients with a modern TKA prosthesis, compared to 40 matched control participants when ascending and descending stairs. Fewer patients were able to ascend (65%) or descend stairs (53%) unassisted than controls (83%)....
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2014.03.026
更新日期：2014-06-03 00:00:00
abstract：:Previous epidemiological studies indicate that the use of thumb-push mechanical pipettes is associated with musculoskeletal disorders (MSDs) in the hand. The goal of the current study was to analyze the loading in the muscle-tendon units in the thumb during pipetting. The hand is modeled as a multi-body linkage system...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2013.11.015
更新日期：2014-01-22 00:00:00
abstract：:Human responses are critical to understanding injury biomechanics in blunt ballistic impacts, which are defined as 20-200 g projectiles impacting at 20-250 m/s. 13 human cadavers were exposed to three distinct ballistic impacts of the chest to determine force-time, deflection-time and force-deflection responses. Compa...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/s0021-9290(03)00238-0
更新日期：2004-01-01 00:00:00
abstract：:Mechanical environment in callus is determinant for the evolution of bone healing. However, recent mechanobiological computational works have underestimated the effect that growth exerts on the mechanical environment of callus. In the present work, we computationally evaluate the significance of growth-induced stresse...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2011.04.021
更新日期：2011-06-03 00:00:00
abstract：:This study evaluated the feasibility of assessing continuous strain distributions on fracture callus cross-sections with an electronic speckle pattern interferometry (ESPI) system. Mid-sagittal callus cross-sections were harvested from ovine tibiae. One low stiffness (LS) specimen and one high stiffness (HS) specimen ...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2007.10.024
更新日期：2008-01-01 00:00:00
abstract：:Mucosal folding in such biological vessels as esophagus and airway is essential to their physiological functions and can be affected by some diseases, e.g., inflammation, edema, lymphoma, and asthma. A biomechanical model within the framework of finite deformation theory is proposed to address the mucosal folding indu...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2010.09.007
更新日期：2011-01-04 00:00:00
abstract：:Interpatient variability is often overlooked in orthopaedic computational studies due to the substantial challenges involved in sourcing and generating large numbers of bone models. A statistical model of the whole femur incorporating both geometric and material property variation was developed as a potential solution...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2009.05.038
更新日期：2009-09-18 00:00:00
abstract：:Studies of proximal femoral strength usually involve one of two types of loading conditions, loading similar to joint loading during single-limb stance or loading simulating impact from a fall. When interpreting the results of studies involving only one of these load configurations, the question arises as to their app...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/s0021-9290(99)00202-x
更新日期：2000-04-01 00:00:00
abstract：:The present study investigated the feasibility and reliability of continuous relative phase (CRP) and deviation phase (DP) to assess intersegmental hind limb coordination pattern and coordination variability in rats during walking. Twenty-six adult rats walked at 8 m/min, 12 m/min and 16 m/min while two-dimensional ki...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2018.03.045
更新日期：2018-05-17 00:00:00
abstract：:Continuous dynamic multi-segmental studies of lumbar motion have added depth to our understanding of the biomechanics of back pain, but few have attempted to continuously measure the proportions of motion accepted by individual levels. This study attempted to compare the motion contributions of adjacent lumbar levels ...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2020.109603
更新日期：2020-03-26 00:00:00
abstract：:This study investigated spatio-temporal variables, ground reaction forces and sagittal and frontal plane kinematics during the stance phase of nine trained subjects running barefoot and shod at three different velocities (3.5, 4.5, 5.5 m s(-1)). Differences between conditions were detected with the general linear meth...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/s0021-9290(99)00192-x
更新日期：2000-03-01 00:00:00
abstract：:Total disc arthroplasty (TDA) can be used to replace a degenerated intervertebral disc in the spine. There are different designs of prosthetic discs, but one of the most common is a ball-and-socket combination. Contact between the bearing surfaces can result in high frictional torque, which can then result in wear and...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2011.11.045
更新日期：2012-02-02 00:00:00
abstract：:Rigid body attitude and single-joint kinematics are typically expressed using three Cardan angles which represent rotations in anatomical planes. It was recently shown in the Biomechanics literature that Cardan angles inaccurately estimate true mean attitude due to an important mathematical inadequacy: attitude under-...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2020.109976
更新日期：2020-10-09 00:00:00
abstract：:During normal daily activity, muscle motor units (MUs) develop unfused tetanic contractions evoked by trains of motoneuronal firings at variable interpulse intervals (IPIs). The mechanical responses of a MU to successive impulses are not identical. The aim of this study was to develop a mathematical approach for the p...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2010.01.034
更新日期：2010-05-28 00:00:00
abstract：:This communication extends the recently reported cell-specific finite element (FE) method in Slomka and Gefen (2010) in which geometrically realistic FE cell models are created from confocal microscopy scans for large deformation analyses. The cell-specific FE method is extended here in the following aspects: (i) we d...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2010.09.012
更新日期：2011-02-03 00:00:00
abstract：:Understanding the mechanisms of instability can aid in reducing fall risk. As a sensitive measure of fall risk, the distance between the center of pressure (COP) and center of mass (COM) is currently assessed through discrete points assumed to represent physiological important fall mechanisms. However, it is unclear i...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2020.109899
更新日期：2020-07-17 00:00:00
abstract：:An experimental setup was developed for statically measuring seven vertical and three horizontal reaction forces on the foot. In the setup, the leg can be simultaneously loaded (1) by a vertical force, (2) by an externally applied axial moment, and (3) by simulated muscle forces. The foot is free to invert under influ...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/0021-9290(89)90080-8
更新日期：1989-01-01 00:00:00
abstract：:The purpose of this study was to determine if the characteristic banding pattern (D-period) of collagen fibrils from rabbit medial collateral ligaments changes as a function of gross ligament strain and, if so, whether the changes are location dependent (insertion versus midsubstance). Femur-medial collateral ligament...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/s0021-9290(00)00150-0
更新日期：2000-12-01 00:00:00
abstract：:Meaningful testing of stab resistant body armour requires the use of realistic body tissue simulants. A device for the determination of the force-displacement behaviour of materials in high impact loading situations has been developed for the testing of such simulants. Force measurement is achieved with the use of ele...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/s0021-9290(99)00191-8
更新日期：2000-03-01 00:00:00
abstract：:Knee kinetic asymmetries are present during jump-landings in athletes returning to sport following anterior cruciate ligament (ACL) reconstruction, and are associated with an increased risk for sustaining a second ACL injury. The loadsol® is a wireless load sensing insole that can be used in non-laboratory settings. T...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2019.07.037
更新日期：2019-10-11 00:00:00
abstract：:Identification of the localized mechanical response of the plantar soft tissue pads underneath the metatarsal heads (i.e., sub-MTH pad) to external loading is key to understand and predict how it functions in a gait cycle. The mechanical response depends on various parameters, such as the external load (direction and ...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2011.03.031
更新日期：2011-06-03 00:00:00
abstract：:There are many diseases which cause detrimental changes in the trabecular structure of cancellous bone, leading to mechanical failure of the tissue. One approach to understanding the mechanisms of these diseases is to create idealized models that recreate the morphology of the tissue. This paper presents a partial dev...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/0021-9290(93)90057-l
更新日期：1993-08-01 00:00:00
abstract：:The use of cadavers for orthopaedic biomechanics research is well established, but presents difficulties to researchers in terms of cost, biosafety, availability, and ease of use. High fidelity composite models of human bone have been developed for use in biomechanical studies. While several studies have utilized comp...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2015.12.050
更新日期：2016-02-29 00:00:00
abstract：:The paper defines the term coordination interval (CI), suggesting that it should replace the term electromechanical delay (EMD), if this parameter is determined in vivo for a muscle functioning in a biomechanical system with considerable mobility, but not in a kinematic pair with one degree of rotational freedom (DOF)...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/0021-9290(94)90211-9
更新日期：1994-02-01 00:00:00
abstract：:Exposure following pelvic organ prolapse repair has been observationally associated with wrinkling of the implanted mesh. The purpose of this study was to quantify the impact of variable boundary conditions on the out-of-plane deformations of mesh subjected to tensile loading. Using photogrammetry and surface curvatur...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2015.02.061
更新日期：2015-06-25 00:00:00
abstract：:In this work we propose a method to estimate the elastic properties of the extracellular matrix of articular cartilage, once the elastic properties of the chondrocytes and the whole tissue are known. The influence of the elastic properties of the tissue and the cell concentration on the estimated elastic properties of...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/s0021-9290(03)00280-x
更新日期：2004-03-01 00:00:00
abstract：:An arterial graft with a corrugated cylindrical cross-section has been proposed as a partial solution to the problem of elastic stiffness mismatch between conventional grafts and arterial tissue (Trescony et al., 1994, US Patent 5,282, 847 (granted February 1 1994)). A two-dimensional ring theory model and a finite el...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/s0021-9290(98)00084-0
更新日期：1998-08-01 00:00:00
abstract：:Computation of muscle excitation patterns that produce coordinated movements of muscle-actuated dynamic models is an important and challenging problem. Using dynamic optimization to compute excitation patterns comes at a large computational cost, which has limited the use of muscle-actuated simulations. This paper int...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/s0021-9290(02)00432-3
更新日期：2003-03-01 00:00:00
abstract：:Development of biologically inspired exoskeletons to assist soldiers in carrying load is a rapidly expanding field. Understanding how the body modulates stiffness in response to changing loads may inform the development of these exoskeletons and is the purpose of the present study. Seventeen subjects walked on a tread...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2014.12.046
更新日期：2015-04-13 00:00:00
abstract：:Baropodometry and multi-segmental foot kinematics are frequently employed to obtain insight into the mechanics of the foot-ground interaction in both basic research and clinical settings. However, nothing hitherto has been reported on the full integration of kinematics with baropodometric parameters, and only a few st...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2014.05.014
更新日期：2014-08-22 00:00:00
