Collagen fibril D-period may change as a function of strain and location in ligament.

Abstract:

:The purpose of this study was to determine if the characteristic banding pattern (D-period) of collagen fibrils from rabbit medial collateral ligaments changes as a function of gross ligament strain and, if so, whether the changes are location dependent (insertion versus midsubstance). Femur-medial collateral ligament-tibia complexes were strained to 0, 8, or 12% and immediately chemically fixed in situ. Samples were taken from the medial collateral ligament midsubstance and bony insertions, and prepared for and observed under a transmission electron microscope. D-period length was measured and found to increase (albeit not significantly so, p=0. 1) as a function of gross strain for samples obtained from the insertion sites but not for samples obtained from the ligament midsubstance. Results suggested that ligament strains are inhomogeneous at the ultrastructural level.

journal_name

J Biomech

journal_title

Journal of biomechanics

authors

Kukreti U,Belkoff SM

doi

10.1016/s0021-9290(00)00150-0

keywords:

subject

Has Abstract

pub_date

2000-12-01 00:00:00

pages

1569-74

issue

12

eissn

0021-9290

issn

1873-2380

pii

S0021-9290(00)00150-0

journal_volume

33

pub_type

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