Immunological characterization of novel secreted antigens of Mycobacterium tuberculosis.

abstract：:This study investigated the expression of the neonatal Fc receptor (FcRn) in maternal blood, cord blood and placental cells and determined IgG levels in maternal blood and cord blood from diabetic mothers. Peripheral blood, cord blood and placenta samples were collected from 26 mothers with normoglycaemia (non-diabeti...

journal_title：Scandinavian journal of immunology

authors： de Souza EG,Hara CC,Fagundes DL,de Queiroz AA,Morceli G,Calderon IM,França EL,Honorio-França AC

更新日期：2016-10-01 00:00:00

abstract：:Two monoclonal antibodies (MoAbs), F10.2 and F10.3, were selected for their ability to interfere in homotypic adhesion of human B cells. Precipitation studies and binding to intercellular adhesion molecule 1 (ICAM-1, CD54) cDNA transfected COS cells revealed that both MoAbs are directed against ICAM-1. The binding of ...

journal_title：Scandinavian journal of immunology

authors： Bloemen P,Moldenhauer G,van Dijk M,Schuurman HJ,Bloem AC

更新日期：1992-05-01 00:00:00

abstract：:The major rheumatoid factor cross-reactive idiotype, which was defined by prototypic monoclonal IgM rheumatoid factors from Waldenstrom's macroglobulinaemia patient Wa, is present on 60% of all monoclonal IgM RF paraproteins. One-third of patients with juvenile rheumatoid arthritis (JRA), who are seronegative for clas...

journal_title：Scandinavian journal of immunology

authors： Ilowite NT,Wedgwood JF,Moore TL,Ramakrishnan T,Bonagura VR

更新日期：1991-10-01 00:00:00

abstract：:The objective of this study was to evaluate whether major abdominal surgery leads to complement activation and interleukin response and whether the kind of anaesthesia influence complement activation and the release of inflammatory interleukins. The study design was prospective and randomised. Fifty patients undergoin...

journal_title：Scandinavian journal of immunology

authors： Kvarnström AL,Sarbinowski RT,Bengtson JP,Jacobsson LM,Bengtsson AL

更新日期：2012-05-01 00:00:00

abstract：:Autoimmune regulator's (AIRE) best characterized role is in the generation immunological tolerance, but it is also involved in many other processes such as spermatogenesis. Loss-of-function mutations in AIRE cause a disease called autoimmune polyendocrinopathy, candidiasis and ectodermal dystrophy (APECED; also called...

journal_title：Scandinavian journal of immunology

authors： Kekäläinen E,Pöntynen N,Meri S,Arstila TP,Jarva H

更新日期：2015-05-01 00:00:00

abstract：:Normal mouse spleen cells were cultured in different conditioned media (CM). Mixed lymphocyte culture supernatant (MLC SN) was shown to promote the proliferation of cytotoxic, Thy-1+, Lyt-1+, Lyt-2+, asialo-GM-1+, weakly adherent cells with numerous vacuoles and lysosome-like cytoplasmic granules. In contrast, the Con...

journal_title：Scandinavian journal of immunology

authors： Courtoy R,Schaaf-Lafontaine N,Degiovanni G,Boniver J

更新日期：1983-08-01 00:00:00

abstract：:Prolonged antigenic stimulation results in lymphocyte shedding of CD27, a member of the tumour necrosis factor receptor (TNFR) family, and transformation to a stable phenotype capable of synthesizing interleukin-4 (IL-4). Co-expression of alpha4beta7 identifies those cells with gut-homing potential. We have investigat...

journal_title：Scandinavian journal of immunology

authors： Meenan J,Spaans J,Grool TA,Lammers K,Pals S,Tytgat GN,van Deventer SJ

更新日期：1998-09-01 00:00:00

abstract：:Rabbit Ig against human beta2-microglobulin was found to be mitogenic for human peripheral lymphocytes, tonsil lymphocytes, and appendix and spleen cells. Anti-beta2-m gave increased DNA synthesis, with peak responses on day 3 or 4 and showed a dose-response effect when diluted. The effect was seen in both serum-free ...

journal_title：Scandinavian journal of immunology

authors： Ringeén O,Möller E

更新日期：1975-01-01 00:00:00

abstract：:Granulomatous lymphomatosis is an Epstein-Barr virus (EBV)-driven B cell proliferation associated with an exuberant CD4(+) T cell reaction with usually histopathological pictures of angiocentrism. So far, the characteristics of CD4(+) T cells in granulomatous lymphomatosis and the mechanism leading to their expansion ...

journal_title：Scandinavian journal of immunology

authors： Cervera P,Guihot A,Gorochov G,Lassoued K,Coppo P

更新日期：2015-12-01 00:00:00

abstract：:Approximately 70% of kidney transplant recipients are non-responders to conventional hepatitis B virus (HBV) vaccines. We examined whether Fendrix™, an HBV vaccine containing 3-O-desacyl-4'-monophosphoryl lipid A (MPL) as adjuvant, could induce HBV immunity in these patients and compared their vaccination efficacy wit...

journal_title：Scandinavian journal of immunology

authors： Lindemann M,Zaslavskaya M,Fiedler M,Wilde B,Heinemann FM,Heinold A,Horn PA,Witzke O

更新日期：2017-01-01 00:00:00

abstract：:Human monocytes activated with lymphokines after 3-7 days of in vitro maturation released stable cytostatic factor(s) (CF), as determined by reduction of [methyl-3H]thymidine incorporation and cell counts in target cell cultures. Lipopolysaccharide from Escherichia coli slightly enhanced the release of CF. The CF rele...

journal_title：Scandinavian journal of immunology

authors： Hammestrøm J

更新日期：1982-03-01 00:00:00

abstract：:The production of type 1 (interferon or IFN-gamma) and type 2 (interleukin or IL-4 and IL-10) cytokines by mitogen-stimulated peripheral blood mononuclear cells (PBMCs) obtained from asymptomatic human immunodeficiency virus-seropositive (HIV+) patients untreated with any antiviral, antibacterial or antimycotic drugs,...

journal_title：Scandinavian journal of immunology

authors： Canaris AD,Caruso A,Licenziati S,Cantalamessa A,De Francesco MA,Fallacara F,Fiorentini S,Dima F,Martinelli F,Manca N,Balsari A,Turano A

更新日期：1998-02-01 00:00:00

abstract：:Monoclonal anti-HLA-DR antibodies inhibited the production of interleukin-2 (IL-2) when added from the initiation of autologous (AMLR) and allogeneic (MLR) mixed lymphocyte reactions, but not 60 h later. The inhibitory activity of the anti-DR sera became apparent 8 h after initiation of the cultures and was maintained...

journal_title：Scandinavian journal of immunology

authors： Palacios R

更新日期：1981-09-01 00:00:00

abstract：:Mitogen-induced cell-mediated cytotoxicity (MICC) of human peripheral blood granulocytes (PMN) and lymphocytes (PBL) was studied by using chicken erythrocytes as targets. The possible mechanisms were elicited bidirectionally by means of the MICC inhibition test and by functional analysis of lectin. In our preliminary ...

journal_title：Scandinavian journal of immunology

authors： Yue CL,Tanimoto K,Horiuchi Y

更新日期：1981-10-01 00:00:00

abstract：:Myasthenia gravis (MG) and its animal model experimental autoimmune MG (EAMG), are T-cell dependent, antibody-mediated autoimmune disorders. A dual altered peptide ligand (APL) composed of the tandemly arranged two single amino acids analogs of two myasthenogenic peptides, p195-212 and p259-271, was demonstrated to do...

journal_title：Scandinavian journal of immunology

authors： Ben-David H,Venkata Aruna B,Sela M,Mozes E

更新日期：2007-06-01 00:00:00

abstract：:Atrial fibrillation is highly prevalent, and affected patients are at an increased risk of a number of complications, including heart failure and thrombo-embolism. Over the past years, there has been increasing interest in the role of inflammatory processes in atrial fibrillation, from the first occurrence of the arrh...

journal_title：Scandinavian journal of immunology

authors： Lappegård KT,Hovland A,Pop GA,Mollnes TE

更新日期：2013-08-01 00:00:00

abstract：:Using rocket immunoelectrophoresis and indirect haemagglutination tests, antibodies to nicotinic acetylcholine receptor (n-AChR) from Torpedo marmorata were detected in sera from rabbits with experimental myasthenia but not in sera from patients with myasthenia gravis or in rabbit antisera to a partly purified skeleta...

journal_title：Scandinavian journal of immunology

authors： Aarli JA,Mattsson C,Heilbronn E

更新日期：1975-01-01 00:00:00

abstract：:The humoral response against the bacterial polysaccharide antigen alpha(1-->3) dextran (Dex) is controlled by J558 idiotype-(Id) specific T cells. These T cells of which the cell clone 178-4 Ts is a representative by all relevant criteria, recognize J558 Id-bearing B cells in an I-Ed-restricted manner. Costimulation v...

journal_title：Scandinavian journal of immunology

authors： Rademaekers A,Specht C,Kölsch E

更新日期：2001-03-01 00:00:00

abstract：:Immunoglobulin-secreting cells (ISC) in the peripheral blood of healthy individuals and in the bone marrow, peripheral blood, or plasmacytomas of patients with multiple myeloma were enumerated by a protein-A plaque-forming cell assay after treatment with anti-Ia antibody and complement. Rabbit anti-human B-cell antise...

journal_title：Scandinavian journal of immunology

authors： Nagai K,Nagai T,Takatsuki K,Uchino H

更新日期：1982-06-01 00:00:00

abstract：:It has not been considered so far that antigen-presenting cells (APC) may phagocytose immunogenic material from autologous cancer cells. Assuming the presence of cancer-immunogenic material in APC, we developed a novel autologous priming method that does not require tumour cells or identified peptides. Cancer-immunoge...

journal_title：Scandinavian journal of immunology

authors： Laumbacher B,Gu S,Wank R

更新日期：2012-03-01 00:00:00

abstract：:Modulation of cytotoxic responses by viral immunoevasins plays an important role in the establishment of latent and persistent viral infections. Together with MHC class-I-restricted CD8T-lymphocytes, non-MHC-restricted natural killer (NK) and lymphokine-activated killer (LAK) cells participate in this anti-viral contr...

journal_title：Scandinavian journal of immunology

authors： Cartier A,Masucci MG

更新日期：2004-12-01 00:00:00

abstract：:The enhancement of the lytic capacity of mouse splenic 'natural killer' (NK) cells by interferon has been studied in vitro as a model for NK cell differentiation from inactive immediate precursors. We show that the increased cytotoxicity is a function of interferon concentration, and that two stages in the NK cell dif...

journal_title：Scandinavian journal of immunology

authors： Senik A,Kolb JP,Orn A,Gidlund M

更新日期：1980-01-01 00:00:00

abstract：:The detection of mRNA in the murine model of tuberculosis for key cytokines involved in protective immunity in the lung tissues revealed a much faster emergence of the interferon (IFN)-gamma response in the intravenous route than in the aerosol route of inoculation. This slower response in the lungs was associated wit...

journal_title：Scandinavian journal of immunology

authors： Cardona PJ,Cooper A,Luquín M,Ariza A,Filipo F,Orme IM,Ausina V

更新日期：1999-04-01 00:00:00

abstract：:Conditions for the cloning of alloactivated human lymphocytes by limiting dilution in the presence of interleukin 2 (IL 2) and filler cells have been investigated. Cloning efficiencies were extremely high (at least 40%) when IL 2 derived from pooled peripheral blood mononuclear cells (PBM), stimulated with phytohaemag...

journal_title：Scandinavian journal of immunology

authors： Kahle P,Wernet P,Rehbein A,Kumbier I,Pawelec G

更新日期：1981-11-01 00:00:00

abstract：:The immune response of adult BALB/c mice against the bacterial antigen dextran B1355S (Dex) is well characterized as thymus independent (TI type 2) and Igha linked. The antisera consist of mainly IgM/lambda antibodies directed against the alpha(1-->3) glucosidic linkage. This study describes the immune response agains...

journal_title：Scandinavian journal of immunology

authors： Willers J,Weiler E,Kolb C

更新日期：1995-09-01 00:00:00

abstract：:When the immunoglobulin secretion of 172 normal healthy individuals was investigated with the protein-A plaque assay, 12 persons (7%) did not develop any plaque-forming cells (PFC) in cultures of pokeweed mitogen (PWM)-activated unfractionated peripheral blood lymphocytes (PBL), incubated for 6 days. The effect of irr...

journal_title：Scandinavian journal of immunology

authors： Tauris P

更新日期：1983-09-01 00:00:00

abstract：:The activation of complement and the release of TNF-alpha, IL-6 and IL-8 are important pathogenic factors behind organ dysfunction in sepsis. The aim of this study was to determine whether infusion of anti-TNF antibodies alters complement activation and plasma concentrations of pro-inflammatory cytokines at high doses...

journal_title：Scandinavian journal of immunology

authors： Bengtsson A,Redl H,Schlag G,Högåsen K,Götze O,Mollnes TE

更新日期：1998-11-01 00:00:00

abstract：:The aim of this study was to examine whether the unresponsiveness of MHC class I-negative subclones of the EL4 thymoma to CD3 cross-linking can be restored by transfection of class I genes into the H-2-negative cells. Cell activation experiments with selected MHC class I-negative subclones and H-2b- and H-2Ld-positive...

journal_title：Scandinavian journal of immunology

authors： Claesson MH,Dissing S,Plesner T,Sturmhöfel K,Brams P

更新日期：1990-07-01 00:00:00

abstract：:HLA class II determinants were analysed for their role in monocyte-T-cell interactions in the proliferative response to purified protein derivative (PPD). Allogeneic cell combinations of monocytes and T cells were tested with a range of suboptimal PPD concentrations. For each cell combination tested, a summary measure...

journal_title：Scandinavian journal of immunology

authors： van Eden W,Elferink BG,Hermans J,de Vries RR,van Rood JJ

更新日期：1984-12-01 00:00:00

abstract：:Rheumatoid factor (RF), i.e. a family of autoantibodies against the Fc part of IgG, is an important seromarker of rheumatoid arthritis (RA). Traditional particle agglutination without disclosing the antibody isotype remains the predominating diagnostic method in clinical routine. Although IgG-RF attracts pathogenic in...

journal_title：Scandinavian journal of immunology

authors： Kanmert D,Kastbom A,Almroth G,Skogh T,Enander K,Wetterö J

更新日期：2012-01-01 00:00:00