Enhancement of the biodegradability of aromatic groundwater contaminants.

Abstract:

:Groundwater (GW) from the Bitterfeld industrial region, Central Germany, is contaminated mainly with monochlorobenzene (MCB). Accordingly, current research addresses the development of feasible in situ groundwater remediation technologies. Although easily degradable under aerobic conditions, MCB persists in the essentially anaerobic Bitterfeld aquifer. Therefore, we focused on primary oxidation of MCB and the subsequent anaerobic biodegradability of MCB oxidation products by the indigenous microbial community. In groundwater microcosms, most efficient MCB removal was observed upon treatment with Fenton's reagent (H2O2 + Fe2+), which produces the highly reactive hydroxyl radical and Fe3+ simultaneously. Phospholipid fatty acid analysis following different treatments suggested respective shifts of the microbial community compositions, and indicated that Fenton's reagent had a rather beneficial than an adverse effect on biomass development. Potential metabolites of hydroxyl radical attack on MCB such as chlorohydroquinone, hydroquinone, catechol, resorcinol, and phenol were anaerobically degraded by the groundwater microbial community under Fe3+ -reducing conditions.

journal_name

Toxicology

journal_title

Toxicology

authors

Bittkau A,Geyer R,Bhatt M,Schlosser D

doi

10.1016/j.tox.2004.06.052

keywords:

subject

Has Abstract

pub_date

2004-12-15 00:00:00

pages

201-10

issue

3

eissn

0300-483X

issn

1879-3185

pii

S0300-483X(04)00382-8

journal_volume

205

pub_type

杂志文章
  • The effect of nitrofen [4-(2,4-dichlorophenoxy)nitrobenzene] on the reproductive performance of male rats.

    abstract::Technical grade nitrofen was fed to 4 groups (25/group) of male Sprague-Dawley rats for 13 weeks at dietary concentrations of 0, 100, 500, or 2500 ppm. Untreated female rats of the same age and strain were mated with treated males and fertility, gestation, and lactation indices were monitored. After mating, males were...

    journal_title:Toxicology

    pub_type: 杂志文章

    doi:10.1016/0300-483x(83)90006-9

    authors: O'Hara GP,Chan PK,Harris JC,Burke SS,Smith JM,Hayes AW

    更新日期:1983-11-01 00:00:00

  • Hematological changes produced in mice by ochratoxin A and citrinin.

    abstract::The effect of 6 weekly injections of ochratoxin A (5 mg/kg) and citrinin (20 mg/kg) on the following hematological indices of mice was studied: erythrocyte sedimentation rate, hematocrit percentage, mean corpuscular values, red cell indices, platelet count, total count of bone marrow cells, differential count of bone ...

    journal_title:Toxicology

    pub_type: 杂志文章

    doi:10.1016/0300-483x(83)90056-2

    authors: Gupta M,Sasmal D,Bandyopadhyay S,Bagchi G,Chatterjee T,Dey S

    更新日期:1983-01-01 00:00:00

  • Detection of autoantibody to aldolase B in sera from patients with troglitazone-induced liver dysfunction.

    abstract::Troglitazone is a thiazolidinedione antidiabetic agent with insulin-sensitizing activities that was withdrawn from the market in 2000 due to its association with idiosyncratic hepatotoxicity. To address the suspected autoantibody production associated with troglitazone, we investigated autoantibodies in sera from pati...

    journal_title:Toxicology

    pub_type: 杂志文章

    doi:10.1016/j.tox.2005.07.012

    authors: Maniratanachote R,Shibata A,Kaneko S,Yamamori I,Wakasugi T,Sawazaki T,Katoh K,Tokudome S,Nakajima M,Yokoi T

    更新日期:2005-12-01 00:00:00

  • Application of support vector machine (SVM) for prediction toxic activity of different data sets.

    abstract::As a new method, support vector machine (SVM) were applied for prediction of toxicity of different data sets compared with other two common methods, multiple linear regression (MLR) and RBFNN. Quantitative structure-activity relationships (QSAR) models based on calculated molecular descriptors have been clearly establ...

    journal_title:Toxicology

    pub_type: 杂志文章

    doi:10.1016/j.tox.2005.08.019

    authors: Zhao CY,Zhang HX,Zhang XY,Liu MC,Hu ZD,Fan BT

    更新日期:2006-01-16 00:00:00

  • Decreased H3K9ac level of StAR mediated testicular dysplasia induced by prenatal dexamethasone exposure in male offspring rats.

    abstract::Prenatal dexamethasone exposure (PDE) could induce testicular developmental toxicity in adults. The present study aims to confirm its intrauterine origination, and to explore its potential intrauterine programming mechanism. The pregnant rats were respectively injected subcutaneously with 0.2 and 0.8 mg/kg d dexametha...

    journal_title:Toxicology

    pub_type: 杂志文章

    doi:10.1016/j.tox.2018.06.005

    authors: Liu M,Chen B,Pei L,Zhang Q,Zou Y,Xiao H,Zhou J,Chen L,Wang H

    更新日期:2018-09-01 00:00:00

  • Does methamphetamine affect bone metabolism?

    abstract::There is a close relationship between the central nervous system activity and bone metabolism. Therefore, methamphetamine (METH), which stimulates the central nervous system, is expected to affect bone turnover. The aim of this study was to investigate the role of METH in bone metabolism. Mice were divided into 3 grou...

    journal_title:Toxicology

    pub_type: 杂志文章

    doi:10.1016/j.tox.2014.01.014

    authors: Tomita M,Katsuyama H,Watanabe Y,Okuyama T,Fushimi S,Ishikawa T,Nata M,Miyamoto O

    更新日期:2014-05-07 00:00:00

  • Psychophysiologic effects of early lead exposure.

    abstract::In several separate experiments neonatal rats were intubated daily with 9, 27 or 81 mg lead acetate/kg of body weight throughout their 3-week postnatal period of development. Based on average body weights, the total daily lead intake was 0.156, 0.454 or 1.384 mg lead per animal, respectively (in addition to normal lea...

    journal_title:Toxicology

    pub_type: 杂志文章

    doi:10.1016/0300-483x(75)90115-8

    authors: Sobotka TJ,Brodie RE,Cook MP

    更新日期:1975-11-01 00:00:00

  • Mechanism of delta-aminolevulinate dehydratase inhibition by phenyl selenoacetylene involves its conversion to diphenyl diselenide.

    abstract::The mechanism of delta-aminolevulinate dehydratase (delta-ALA-D) inhibition by phenyl selenoacetylene in vitro was investigated in this study. Phenyl selenoacetylene (40-400 microM) inhibition of delta-aminolevulinate dehydratase from rat liver (low speed supernatant fraction, S1 fraction) was partially prevented by i...

    journal_title:Toxicology

    pub_type: 杂志文章

    doi:10.1016/j.tox.2004.08.001

    authors: Folmer V,Bolzan RC,Farina M,Zeni G,Nogueira CW,Emanuelli T,Rocha JB

    更新日期:2005-01-31 00:00:00

  • In-vitro toxicity of molybdenum trioxide nanoparticles on human keratinocytes.

    abstract::Molybdenum trioxide (MoO3) nanoparticles (NPs) embedded in polymer films have been proposed as a cheap way of producing antibacterial coatings on external surfaces. Recently, we synthesized MoO3 nanowires in a unique shape and degree of anisotropy, which enables their fast water dissolution and quick antimicrobial rea...

    journal_title:Toxicology

    pub_type: 杂志文章

    doi:10.1016/j.tox.2020.152564

    authors: Božinović K,Nestić D,Centa UG,Ambriović-Ristov A,Dekanić A,de Bisschop L,Remškar M,Majhen D

    更新日期:2020-11-01 00:00:00

  • Chromium(III) complexes inhibit transcription factors binding to DNA and associated gene expression.

    abstract::Role of chromium(III) in biological systems is controversial and no significant conclusions can be arrived with the available data. Chromium(VI) enters in to the cell readily and gets reduced to form stable chromium(III) complexes. Chromium(III) complexes react slowly and were considered non-toxic. Recent studies sugg...

    journal_title:Toxicology

    pub_type: 杂志文章

    doi:10.1016/j.tox.2008.07.052

    authors: Raja NS,Nair BU

    更新日期:2008-09-29 00:00:00

  • Effects of the benomyl metabolite, carbendazim, on the hypothalamic-pituitary reproductive axis in the male rat.

    abstract::Carbendazim (MBC), the bioactive metabolite of the fungicide benomyl, has been reported to induce a number of testicular alterations in male rats. Since it is possible that extragonadal changes contribute to the appearance of such effects, the present study focused on the presence of concurrent endocrine changes in th...

    journal_title:Toxicology

    pub_type: 杂志文章

    doi:10.1016/0300-483x(89)90163-7

    authors: Goldman JM,Rehnberg GL,Cooper RL,Gray LE Jr,Hein JF,McElroy WK

    更新日期:1989-07-17 00:00:00

  • Oxime-assisted reactivation of tabun-inhibited acetylcholinesterase analysed by active site mutations.

    abstract::The antidotal property of oximes is attributed to their ability to reactivate acetylcholinesterase (AChE) inhibited by organophosphorus compounds (OP) such as pesticides and nerve warfare agents. Understanding their interactions within the active site of phosphylated AChE is of great significance for the search for mo...

    journal_title:Toxicology

    pub_type: 杂志文章

    doi:10.1016/j.tox.2018.05.008

    authors: Katalinić M,Šinko G,Maček Hrvat N,Zorbaz T,Bosak A,Kovarik Z

    更新日期:2018-08-01 00:00:00

  • In vitro activation assays with hepatic S9 preparation from wild and laboratory reared woodchucks in the Salmonella mutagenicity test.

    abstract::The Salmonella mutagenicity assay was utilized to compare hepatic S9 fractions derived from wild and laboratory reared woodchucks (Marmota monax). Two promutagens, 7,12-dimethylbenz[a]anthracence (DMBA) and 2-amino-fluorene (AF) were tested at 5 concentrations with the tester strains TA98 and TA100, against 2 levels o...

    journal_title:Toxicology

    pub_type: 杂志文章

    doi:10.1016/0300-483x(88)90058-3

    authors: Rashid KA,Babish JG,Mumma RO

    更新日期:1988-01-01 00:00:00

  • The effects of lanthanum chloride on pregnancy in mice and on preimplantation mouse embryos in vitro.

    abstract::A single intraperitoneal injection of 10(-6.5) mol lanthanum chloride/g body wt (44 mg metal/kg body wt) into pregnant mice reduced the number of successful pregnancies and the average litter size. The most susceptible periods of pregnancy were peri-implantation (days 4 and 6) and near-term period (days 14 and 16). In...

    journal_title:Toxicology

    pub_type: 杂志文章

    doi:10.1016/0300-483x(85)90142-8

    authors: Abramczuk JW

    更新日期:1985-03-29 00:00:00

  • Toxicity of alkyldihydrofurans to metabolically active organs in the mouse.

    abstract::Alkylfurans inflict toxicity in several mammalian species to lung, liver and kidney. Organ specificity of the alkylfurans is a sensitive function of the nature of the alkyl group. To determine if this toxicity requires an aromatic ring in the compound, we synthesized 4-methyl-2,3-dihydrofuran, 4-ethyl-2,3-dihydrofuran...

    journal_title:Toxicology

    pub_type: 杂志文章

    doi:10.1016/0300-483x(90)90006-3

    authors: Zenk P,Brinkman R,Gammal L,Penka V,Bresnahan J,Wiley R,Traiger G

    更新日期:1990-03-30 00:00:00

  • Respiratory allergy: what are the uncertainties?

    abstract::The prevalence of asthma is increasing worldwide. The increase has been found for both sexes, for all races and age groups. The factors responsible are unclear. The short period of increase makes it unlikely that a genetic change is responsible but rather suggests that either air pollutants or a behavioral change may ...

    journal_title:Toxicology

    pub_type: 杂志文章,评审

    doi:10.1016/s0300-483x(02)00298-6

    authors: Karol MH

    更新日期:2002-12-27 00:00:00

  • Decreased uptake and altered subcellular disposition of testicular cadmium as possible mechanisms of resistance to cadmium-induced testicular necrosis in inbred mice.

    abstract::Mechanisms responsible for resistance to Cd-induced testicular necrosis in inbred mice were investigated using strains resistant (A/J) or susceptible (129/J) to Cd-induced testicular damage. Cadmium accumulation was measured in testes of both strains 15 min, 30 min, 1 h, 2 h, 6 h, 12 h and 24 h after intravenous injec...

    journal_title:Toxicology

    pub_type: 杂志文章

    doi:10.1016/0300-483x(84)90126-4

    authors: Chellman GJ,Shaikh ZA,Baggs RB

    更新日期:1984-03-01 00:00:00

  • Nrf2 deficiency exacerbates ochratoxin A-induced toxicity in vitro and in vivo.

    abstract::Several mechanisms are postulated to be responsible for nephrotoxic and nephrocarcinogenic activities of mycotoxin and food contaminant, ochratoxin A (OTA). Although Nrf2 transcription factor was suggested to be involved in OTA-mediated renal injury, comprehensive study evaluating the effect of OTA toxicity in Nrf2 kn...

    journal_title:Toxicology

    pub_type: 杂志文章

    doi:10.1016/j.tox.2017.07.004

    authors: Loboda A,Stachurska A,Sobczak M,Podkalicka P,Mucha O,Jozkowicz A,Dulak J

    更新日期:2017-08-15 00:00:00

  • Effects of drug-metabolizing enzyme inducers on cephaloridine toxicity in Fischer 344 rats.

    abstract::High doses of cephaloridine produce necrosis of renal proximal tubular cells and this nephrotoxicity has been shown to be reduced by piperonyl butoxide (a mixed-function oxidase inhibitor) in rats and rabbits, and potentiated by phenobarbital (a mixed-function oxidase inducer) in rabbits but not rats. Phenobarbital is...

    journal_title:Toxicology

    pub_type: 杂志文章

    doi:10.1016/0300-483x(82)90011-7

    authors: Kuo CH,Hook JB

    更新日期:1982-01-01 00:00:00

  • Distribution of chlordecone to liver plasma membranes and recovery from hepatobiliary dysfunction in rats.

    abstract::Chlordecone (CD) impairs biliary excretion of organic anions (including phenolphthalein glucuronide (PG), imipramine polar metabolites, and taurocholate) without evidence of hepatocellular necrosis in rats. In this study we investigated the hypothesis that CD-induced hepatobiliary dysfunction is dependent on CD concen...

    journal_title:Toxicology

    pub_type: 杂志文章

    doi:10.1016/0300-483x(94)90057-4

    authors: Rochelle LG,Curtis LR

    更新日期:1994-01-26 00:00:00

  • Assessment of the sensitization potential of five metal salts in the murine local lymph node assay.

    abstract::The murine local lymph node assay (LLNA) has been proposed as a predictive test for the identification of sensitizing agents. We used this test to compare the sensitization potential of NiSO4, K2Cr2O7, CoCl2, Na2PtCl6 and BeSO4, salts of metals which have all been associated with allergic contact dermatitis and either...

    journal_title:Toxicology

    pub_type: 杂志文章

    doi:10.1016/s0300-483x(97)03629-9

    authors: Mandervelt C,Clottens FL,Demedts M,Nemery B

    更新日期:1997-06-06 00:00:00

  • Cancer initiating properties of fumonisin B1 in a short-term rat liver carcinogenesis assay.

    abstract::The nature of cancer initiation by fumonisin B(1) (FB(1)) was investigated in rat liver by monitoring the effect of phenobarbital (PB) as cancer promoter and evaluating the involvement of spontaneously initiated cells. A PB promoting regimen (0.05% in the diet) stimulated the outgrowth of FB(1)-induced placental gluta...

    journal_title:Toxicology

    pub_type: 杂志文章

    doi:10.1016/j.tox.2008.06.004

    authors: Gelderblom WC,Marasas WF,Lebepe-Mazur S,Swanevelder S,Abel S

    更新日期:2008-09-04 00:00:00

  • Protective effect of sulforaphane pretreatment against cisplatin-induced liver and mitochondrial oxidant damage in rats.

    abstract::In the present work was analyzed whether sulforaphane (SFN) may protect against cisplatin (CIS)-induced hepatic damage, oxidant stress and mitochondrial dysfunction. Four groups of male Wistar rats were studied: control, CIS, CIS+SFN and SFN. SFN was given i.p. (500 μg/kg/d × 3 days) before CIS administration (single ...

    journal_title:Toxicology

    pub_type: 杂志文章

    doi:10.1016/j.tox.2011.04.014

    authors: Gaona-Gaona L,Molina-Jijón E,Tapia E,Zazueta C,Hernández-Pando R,Calderón-Oliver M,Zarco-Márquez G,Pinzón E,Pedraza-Chaverri J

    更新日期:2011-08-15 00:00:00

  • Effects of low concentrations of cadmium on immunoglobulin E production by human B lymphocytes in vitro.

    abstract::Exposure to cadmium (Cd) can cause a variety of biological effects including alterations of immune responses in animals and humans. Both immunosuppression and immunoenhancement have been reported. The present study was aimed at investigating the consequences of exposure to Cd on the human immunoglobulin (Ig) E synthes...

    journal_title:Toxicology

    pub_type: 杂志文章

    doi:10.1016/s0300-483x(03)00044-1

    authors: Jelovcan S,Gutschi A,Kleinhappl B,Sedlmayr P,Barth S,Marth E

    更新日期:2003-06-03 00:00:00

  • Neurotoxicologic investigations of the pesticide dichlorvos (DDVP). Effects on the central and peripheral nervous system.

    abstract::The neurotoxic effect on the central and peripheral nervous system of dichlorvos (DDVP) was investigated by a computer system in acute and subchronic experiments in CFY male rats. The administered peroral doses were given by gavage; the acute group was given a single 88 mg/kg dose and the 2 subchronic groups were give...

    journal_title:Toxicology

    pub_type: 杂志文章

    doi:10.1016/0300-483x(88)90186-2

    authors: Dési I,Nagymajtényi L

    更新日期:1988-04-01 00:00:00

  • Estrogenic effects in fish in The Netherlands: some preliminary results.

    abstract::Recently, a large-scale field study in The Netherlands has focused on the effects of estrogenic contaminants on feral fish populations. The freshwater bream (Abramis brama) and the estuarine flounder (Platichthys flesus) were sampled at a large number of locations in the spring and autumn of 1999. Concentrations of th...

    journal_title:Toxicology

    pub_type: 杂志文章

    doi:10.1016/s0300-483x(02)00271-8

    authors: Vethaak AD,Lahr J,Kuiper RV,Grinwis GC,Rankouhi TR,Giesy JP,Gerritsen A

    更新日期:2002-12-27 00:00:00

  • Evaluation of lethality estimates for combustion gases in military scenarios.

    abstract::To meet the military objective of determining criteria for incapacitation and lethality from toxic gas exposures, a series of small animal tests and data analyses were conducted. Carbon monoxide (CO), a narcotic gas and nitrogen dioxide (NO2), an irritant gas, along with carbon dioxide (CO2) were tested individually a...

    journal_title:Toxicology

    pub_type: 杂志文章

    doi:10.1016/s0300-483x(96)03504-4

    authors: Smith SM,Stuhmiller JH,Januszkiewicz AJ

    更新日期:1996-12-31 00:00:00

  • In vivo hydroquinone exposure impairs allergic lung inflammation in rats.

    abstract::Hydroquinone (HQ) is naturally found in the diet, drugs, as an environmental contaminant and endogenously generated after benzene exposure. Considering that HQ alters the immune system and its several source of exposures in the environment, we hypothesized that prolonged exposure of HQ could affect the course of an im...

    journal_title:Toxicology

    pub_type: 杂志文章

    doi:10.1016/j.tox.2007.08.085

    authors: Macedo SM,Vaz SC,Lourenço EL,de Sousa Mda G,Ligeiro-Oliveira AP,Ferreira JM Jr,Almeida SR,de Lima WT,Farsky SH

    更新日期:2007-11-20 00:00:00

  • p-Dichlorobenzene-induced hepatotoxicity in mice depleted of glutathione by treatment with buthionine sulfoximine.

    abstract::p-Dichlorobenzene (p-DCB) is widely used as a moth repellent and a space deodorant. In mice pretreated with DL-buthionine sulfoximine (BSO; 2 mmol/kg or higher doses, i.p.), an inhibitor of glutathione (GSH) synthesis, administration of p-DCB (100-400 mg/kg, p.o.) resulted in dose-dependent hepatotoxicity as judged by...

    journal_title:Toxicology

    pub_type: 杂志文章

    doi:10.1016/0300-483x(94)90028-0

    authors: Mizutani T,Nakahori Y,Yamamoto K

    更新日期:1994-11-01 00:00:00

  • Digital toxicology education tools: education, training, case studies, and tutorials.

    abstract::This review presents a brief and non-comprehensive overview of a representative sampling of some of the broad array of toxicology-related learning, tutorial and information resources now becoming widely available to educators, health professionals, students and the general public in digital media and/or via the Intern...

    journal_title:Toxicology

    pub_type: 杂志文章

    doi:10.1016/s0300-483x(00)00344-9

    authors: Sharpe JF,Eaton DL,Marcus CB

    更新日期:2001-01-12 00:00:00