High-density methylation of p14ARF and p16INK4A in Epstein-Barr virus-associated gastric carcinoma.

abstract：:Emerging evidence suggests that diffusion-weighted magnetic resonance imaging (DW MRI) could be useful for tumor detection with N and M staging of lung cancer in place of fluorine 18 fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT). DW MRI at 3.0 T and FDG PET/CT were performed before t...

journal_title：International journal of cancer

authors： Zhang J,Cui LB,Tang X,Ren XL,Shi JR,Yang HN,Zhang Y,Li ZK,Wu CG,Jian W,Zhao F,Ti XY,Yin H

更新日期：2014-02-01 00:00:00

abstract：:Tumor cell motility is one of the rate-limiting steps of invasion, which defines progression toward a more malignant phenotype. Elevated expression of epidermal growth factor receptor (EGFR) in many cancers is associated with progression of superficial to invasive forms of the disease. The naturally occuring type III ...

journal_title：International journal of cancer

authors： Pedersen MW,Tkach V,Pedersen N,Berezin V,Poulsen HS

更新日期：2004-02-20 00:00:00

abstract：:Cells of the human lymphoblastoid non-producer line Raji were cloned in soft agar. Individual colonies were isolated and analyzed for their inducibility of the Epstein-Barr virus-associated early antigen (EA). The induction of EA by the tumor promoter TPA varied among the different cell clones. Clones with very high a...

journal_title：International journal of cancer

authors： Bister K,Yamamoto N,zur Hausen H

更新日期：1979-06-15 00:00:00

abstract：:Although childhood exposure to ionizing radiation is a well-established risk factor for thyroid cancer, the risk associated with adulthood exposure remains unclear. We prospectively examined the association between cumulative, low-to-moderate dose occupational radiation exposure to the thyroid and thyroid cancer incid...

journal_title：International journal of cancer

authors： Kitahara CM,Preston DL,Neta G,Little MP,Doody MM,Simon SL,Sigurdson AJ,Alexander BH,Linet MS

更新日期：2018-11-01 00:00:00

abstract：:A simple and rapid variant of in situ hybridization on tissue sections (histo-blotting) usable for detection of specific RNA distribution among tissues is proposed. Tissue sections prepared with a cryostatic microtome are placed on nitrocellulose and these "histo-blots" are hybridized with labelled DNA or RNA probes u...

journal_title：International journal of cancer

authors： Gudkov AV,Kashkin KN,Zaitsevskaya TE,Troyanovsky SM

更新日期：1989-12-15 00:00:00

abstract：:Faecal occult blood test (FOBT) screening for colorectal cancer (CRC) is implemented in several countries. Approximately half of all screen positive persons have negative colonoscopy, but consensus is lacking on how these persons should be followed up. Health authorities in Denmark and The Netherlands recommend suspen...

journal_title：International journal of cancer

authors： Bjerrum A,Andersen O,Fischer A,Lindebjerg J,Lynge E

更新日期：2017-08-01 00:00:00

abstract：:In order to define technical limitations of conventional external beam irradiation for clinically localized prostate cancer, we evaluated the impact of several reduced-field treatment factors, such as reduced-field (RF) irradiated volume, RF technique, photon energy of treatment, and dose on survival endpoints and loc...

journal_title：International journal of cancer

authors： Gagnon GJ,Harter KW,Berg CD,Lynch JH,Cornell DR,Kuettel MR,Dritschilo A

更新日期：2000-10-20 00:00:00

abstract：:The topic of this review is the role of stromal-epithelial interactions in normal and malignant prostatic growth. Because cell-cell interactions and androgens play such key roles in the prostate, the goal of this review will be to apply endocrinologic and developmental concepts to the understanding of normal and malig...

journal_title：International journal of cancer

authors： Cunha GR,Hayward SW,Wang YZ,Ricke WA

更新日期：2003-10-20 00:00:00

abstract：:In previous studies, the antigen CSH-275 (RTNKEASIC) was found expressed in tissue specimens from colorectal cancer but not in normal colonic mucosa. It was also naturally expressed in the DHD-K12 experimental colorectal cancer in BDIX rats. In this study, we describe the effect of vaccination with the synthetic nonap...

journal_title：International journal of cancer

authors： Sinibaldi Vallebona P,Rasi G,Pierimarchi P,Bernard P,Guarino E,Guadagni F,Garaci E

更新日期：2004-05-20 00:00:00

abstract：:Transcription factor c-Jun serves for cellular proliferation, survival, differentiation and transformation and is recognized as an important factor in cancer development, including hepatocellular carcinoma (HCC). The purpose of present study is to determine the involvement of c-Jun in matrix metalloproteinase-1 (MMP-1...

journal_title：International journal of cancer

authors： Sugioka Y,Watanabe T,Inagaki Y,Kushida M,Niioka M,Endo H,Higashiyama R,Okazaki I

更新日期：2004-05-10 00:00:00

abstract：:Tumor-induced immunosuppression remains a major challenge for immunotherapy of cancer patients. To further elucidate why an allogeneic gene-modified [interleukin-7 (IL-7)/CD80-cotransfected] renal cell cancer (RCC) vaccine failed to induce clinically relevant TH-1-polarized immune responses, peripheral blood mononucle...

journal_title：International journal of cancer

authors： Flörcken A,Grau M,Wolf A,Weilemann A,Kopp J,Dörken B,Blankenstein T,Pezzutto A,Lenz P,Lenz G,Westermann J

更新日期：2015-04-15 00:00:00

abstract：:Intratumoural (i.t.) injection of radio-iododeoxyuridine (IdUrd), a thymidine (dThd) analogue, is envisaged for targeted Auger electron- or beta-radiation therapy of glioblastoma. Here, biodistribution of [(125)I]IdUrd was evaluated 5 hr after i.t. injection in subcutaneous human glioblastoma xenografts LN229 after di...

journal_title：International journal of cancer

authors： Buchegger F,Adamer F,Schaffland AO,Kosinski M,Grannavel C,Dupertuis YM,de Tribolet N,Mach JP,Delaloye AB

更新日期：2004-05-20 00:00:00

abstract：:Cutaneous T-Cell lymphoma (CTCL) is a non-Hodgkin's lymphoma of unknown pathogenesis. Mycosis fungoides (MF) is a clinically determined subset of CTCL with intensive infiltration of lymphoma cells into the epidermis. To determine whether Epstein-Barr virus (EBV) is associated with these lymphoma cells, we performed mR...

journal_title：International journal of cancer

authors： Shimakage M,Sasagawa T,Kawahara K,Yutsudo M,Kusuoka H,Kozuka T

更新日期：2001-04-15 00:00:00

abstract：:Pathological deregulation of the transforming growth factor, beta 1 (TGFB1) pathway has been implicated in the development of several major diseases, including cancers. Regulatory variation in the TGFB1 gene may lead to altered TGFB1 expression and activity, and thus, modulate an individual's susceptibility to disease...

journal_title：International journal of cancer

authors： Healy J,Dionne J,Bélanger H,Larivière M,Beaulieu P,Labuda D,Sinnett D

更新日期：2009-09-15 00:00:00

abstract：:There is little long-term follow-up information about how the number of melanoma deaths and case fatality vary over time according to the measured thickness of melanoma at diagnosis. This population-based longitudinal cohort study examines patterns and trends in case fatality among 44,531 people in Queensland (Austral...

journal_title：International journal of cancer

authors： Baade PD,Whiteman DC,Janda M,Cust AE,Neale RE,Smithers BM,Green AC,Khosrotehrani K,Mar V,Soyer HP,Aitken JF

更新日期：2020-09-01 00:00:00

abstract：:Desmoids represent the most important cause of death, after colorectal cancer, in patients affected with familial adenomatous polyposis (FAP), an inherited disease due to mutations in the APC gene. The aims of our study were to estimate the risk of developing desmoids in FAP patients and to evaluate the association be...

journal_title：International journal of cancer

authors： Bertario L,Russo A,Sala P,Eboli M,Giarola M,D'amico F,Gismondi V,Varesco L,Pierotti MA,Radice P,Hereditary Colorectal Tumours Registry.

更新日期：2001-03-20 00:00:00

abstract：:Serum CA 125 concentrations were raised in 90.4% of 115 southern African black patients with hepatocellular carcinoma. Seventy-four percent of 62 patients with amebic hepatic abscess, 60% of 40 patients with chronic hepatic parenchymal disease (chronic hepatitis or cirrhosis), and 60.9% of 41 patients with acute viral...

journal_title：International journal of cancer

authors： Elias J,Kew MC

更新日期：1990-11-15 00:00:00

abstract：:The relationship between occupation and exposure to several occupational agents and Hodgkin's disease (HD) was investigated in a case-control study of 152 cases and 613 controls with acute diseases admitted to all hospitals in Pordenone province, north-east Italy. Among cases, there was a significant excess of individ...

journal_title：International journal of cancer

authors： Franceschi S,Serraino D,La Vecchia C,Bidoli E,Tirelli U

更新日期：1991-07-30 00:00:00

abstract：:The modulating effect on drug resistance of amiodarone (AM) and its metabolite desethylamiodarone (DEA) was studied in a P-glycoprotein-positive human colon carcinoma cell line COLO 320, and a human small-cell lung carcinoma cell line GLC4 and its adriamycin (Adr)-resistant subline GLC4-Adr (both P-glycoprotein-negati...

journal_title：International journal of cancer

authors： van der Graaf WT,de Vries EG,Uges DR,Nanninga AG,Meijer C,Vellenga E,Mulder PO,Mulder NH

更新日期：1991-06-19 00:00:00

abstract：:The variable domain of functional heavy chain antibodies (VHH) devoid of light chains, found in camels, constitute the smallest intact antigen-binding domain fragment. Two camel single-domain fragments, cAb-Lys2 and cAb-Lys3, recognizing an overlapping epitope of lysozyme with a dissociation constant of 2 nM and 65 nM...

journal_title：International journal of cancer

authors： Cortez-Retamozo V,Lauwereys M,Hassanzadeh Gh G,Gobert M,Conrath K,Muyldermans S,De Baetselier P,Revets H

更新日期：2002-03-20 00:00:00

abstract：:Azathioprine (AZ) was injected into C57 Black mice before or after IM implantation of the syngeneic fibrosarcoma FS6, and observations were made on tumour growth and on the cellular composition of the fibrosarcomas. When multiple injections were given to the tumour-bearing host the tumours regressed. The percentage of...

journal_title：International journal of cancer

authors： Evans R

更新日期：1977-07-15 00:00:00

abstract：:The roles of fibroblast growth factor-2 (FGF-2) in the hepatocellular carcinoma (HCC) development are still controversial. In this study, we investigated the expression of FGF-2 in chronic hepatitis (CH) type C patients with or without HCC and the immunoregulation of FGF-2 in NK sensitivity of HCC cells. The FGF-2 exp...

journal_title：International journal of cancer

authors： Tsunematsu H,Tatsumi T,Kohga K,Yamamoto M,Aketa H,Miyagi T,Hosui A,Hiramatsu N,Kanto T,Hayashi N,Takehara T

更新日期：2012-01-15 00:00:00

abstract：:We describe a new, spontaneously occurring BALB/c-derived murine T-cell leukemia. The leukemic cells, designated LB, grow rapidly and progressively in the syngeneic host with no signs of effective immunological resistance. LB cells expressed the Thy-1+, Lyt-2+, L3T4-, CD3- class-I+, CD25+ (IL-2 receptor, IL-2R), class...

journal_title：International journal of cancer

authors： Lugasi H,Hajos S,Murphy JR,Strom TB,Nichols J,Peñarroja C,Naor D

更新日期：1990-01-15 00:00:00

abstract：:The steady-state level of nucleophosmin/B23 mRNA decreased during berberine-induced (25 microg/ml, 24 to 96 hr) apoptosis of human leukemia HL-60 cells. A decline in telomerase activity was also observed in HL-60 cells treated with berberine. A stable clone of nucleophosmin/B23 overexpressed in HL-60 cells was selecte...

journal_title：International journal of cancer

authors： Wu HL,Hsu CY,Liu WH,Yung BY

更新日期：1999-06-11 00:00:00

abstract：:IL-2 gene was introduced through retroviral vectors into the highly malignant and poorly immunogenic 3LL-D122 clone. Both high and low D122-IL-2 secretors showed elimination of tumorigenicity in syngeneic immune-competent mice; however, in nude mice only the high IL-2 secretor showed reduced tumorigenicity as compared...

journal_title：International journal of cancer

authors： Porgador A,Gansbacher B,Bannerji R,Tzehoval E,Gilboa E,Feldman M,Eisenbach L

更新日期：1993-02-01 00:00:00

abstract：:Paclitaxel is widely used to treat cancer patients through the blocking of mitosis and result in formation of polyploidy giant cancer cells (PGCCs), which are generally believed to be nondividing cells or in mitotic catastrophe. Here, we showed that PGCCs following the treatment of paclitaxel of MCF-7 breast cancer ce...

journal_title：International journal of cancer

authors： Zhang S,Mercado-Uribe I,Liu J

更新日期：2014-02-01 00:00:00

abstract：:Management of oral leukoplakia-a potentially malignant disorder-is currently not evidence-based. Of the few randomized trials that have been reported, most have negative data. Therefore, a multi-centre, randomized, double-blind controlled trial (RCT) was undertaken to evaluate the use of low-dose beta-carotene combine...

journal_title：International journal of cancer

authors： Nagao T,Warnakulasuriya S,Nakamura T,Kato S,Yamamoto K,Fukano H,Suzuki K,Shimozato K,Hashimoto S

更新日期：2015-04-01 00:00:00

abstract：:Expression levels of hTERT mRNA were investigated by RT-PCR in tissue specimens of patients with (Group A) and without (Group B) clinically overt bronchial carcinoma, respectively. Bronchial carcinoma (n = 9) and distant normal (n = 9) specimens were analyzed in Group A. The chance of carcinoma seemed to increase with...

journal_title：International journal of cancer

authors： Snijders PJ,Breuer RH,Sutedja TG,Egging M,Voorhorst FJ,Steenbergen RD,van der Linden HC,Risse EK,Berkhof J,de Vries EG,van der Zee AG,Postmus PE,Meijer CJ,Smit EF

更新日期：2004-04-10 00:00:00

abstract：:The variants within the human melanocortin 1 receptor (MC1R) gene are associated with an increased risk of different skin cancers. In this study, we genotyped by direct sequencing, 529 cases of basal cell carcinoma of the skin (BCC) and 533 healthy controls for polymorphisms in the entire MC1R gene. In addition to 10 ...

journal_title：International journal of cancer

authors： Scherer D,Bermejo JL,Rudnai P,Gurzau E,Koppova K,Hemminki K,Kumar R

更新日期：2008-04-15 00:00:00

abstract：:Ninety-eight cases of transitional-cell carcinoma (TCC) of the renal pelvis and ureter, including dysplastic lesions, were studied for tumor incorporation of human papillomavirus (HPV) type-16 and type-18 DNA by in situ hybridization (ISH) with DNA probes for each HPV viral type. Immunohistochemical analysis of p53 ex...

journal_title：International journal of cancer

authors： Furihata M,Yamasaki I,Ohtsuki Y,Sonobe H,Morioka M,Yamamoto A,Terao N,Kuwahara M,Fujisaki N

更新日期：1995-10-20 00:00:00