Occupation and risk of Hodgkin's disease in north-east Italy.

abstract：:Human blood monocytes are very potent to take up antigens. Like macrophages in tissue, they efficiently degrade exogenous protein and are less efficient than dendritic cells (DCs) at cross-presenting antigens to CD8+ T cells. Although it is generally accepted that DCs take up tissue antigens and then migrate to lymph ...

journal_title：International journal of cancer

authors： Faure F,Jouve M,Lebhar-Peguillet I,Sadaka C,Sepulveda F,Lantz O,Berre S,Gaudin R,Sánchez-Ramón S,Amigorena S

更新日期：2018-01-01 00:00:00

abstract：:Human alpha interferon (IFN-alpha) and beta interferon (IFN-beta) showed antiviral and anticellular effects on human lymphoblastoid Daudi and P3HR-1 cells, but up to 1,000 units/ ml of gamma interferon (IFN-gamma) showed no such effect. Though a fairly high level of dsRNA-dependent 2'-5'-oligoadenylate synthetase (2-5...

journal_title：International journal of cancer

authors： Tomita Y,Cantell K,Kuwata T

更新日期：1982-08-15 00:00:00

abstract：:The present experiments were performed to investigate the possibility of inhibiting tumor growth in vivo with syngeneic lymphocytes sensitized in vitro on monolayers of the tumor under test, and to study the effect of a thymic humoral factor (THF) in this sensitization process. Monolayers of fibrosarcoma cells were us...

journal_title：International journal of cancer

authors： Small M,Trainin N

更新日期：1975-06-15 00:00:00

abstract：:The reported beverage habits of 569 lung cancer patients and 569 control patients admitted to Roswell Park Memorial Institute (RPMI) were studied, 355 male cases and 214 female cases being matched to controls within strata of age and residence. Smoking history and an index of vitamin A from vegetables had significant,...

journal_title：International journal of cancer

authors： Mettlin C

更新日期：1989-04-15 00:00:00

abstract：:Metastasis is one of the most important and complex processes in human neoplastic disease. A large number of both positive and negative events must occur to permit a tumor cell to colonize a distant site successfully. To identify mouse strains that harbor dominant genetic modifiers of this process, a strain survey was...

journal_title：International journal of cancer

authors： Lifsted T,Le Voyer T,Williams M,Muller W,Klein-Szanto A,Buetow KH,Hunter KW

更新日期：1998-08-12 00:00:00

abstract：:Mortality rates for cancer of all sites combined and for 12 selected sites or site groups in Estonia from 1965 to 1989 were studied to assess overall progress in controlling cancer. Between 1965-1969 and 1985-1989, age-standardized mortality (world population) increased by 12.0% among males and decreased by 5.1% among...

journal_title：International journal of cancer

authors： Leinsalu M,Rahu M

更新日期：1993-04-01 00:00:00

abstract：:Although new treatments have been widely studied to improve the survival of patients with metastatic breast cancer (BC), prognosis continues to be poor with an average survival time no longer than 3 years. We carried on a population-based study with the purpose of evaluating the outcome of metastatic breast cancer in ...

journal_title：International journal of cancer

authors： Cortesi L,Toss A,Cirilli C,Marcheselli L,Braghiroli B,Sebastiani F,Federico M

更新日期：2015-09-15 00:00:00

abstract：:Improved biomarkers for prostate cancer (PC) risk stratification are urgently needed. Here, we aimed to develop a novel multimarker model for prediction of biochemical recurrence (BCR) after curatively intended radical prostatectomy (RP), based on minimally invasive sampling of blood and urine. We initially measured t...

journal_title：International journal of cancer

authors： Fredsøe J,Rasmussen AKI,Mouritzen P,Borre M,Ørntoft T,Sørensen KD

更新日期：2019-11-01 00:00:00

abstract：:Changes in the expression of a cell membrane antigen during hepatocarcinogenesis and in the developing liver were analyzed by HAM.4, a monoclonal antibody (MAb) against a membrane glycoprotein of normal rat hepatocyte. Of the precancerous lesions observed during hepatocarcinogenesis induced by diethylnitrosamine, 2-ac...

journal_title：International journal of cancer

authors： Matsumoto M,Tamakoshi K,Kanai K,Kako M,Fukumoto T

更新日期：1988-04-15 00:00:00

abstract：:MicroRNA (miRNA) expression is frequently altered in human cancers. To search for epigenetically silenced miRNAs in non-small-cell lung cancer (NSCLC), we mapped human miRNAs on autosomal chromosomes and selected 55 miRNAs in silico. We treated six NSCLC cell lines with the DNA methylation inhibitor 5-aza-2'-deoxycyti...

journal_title：International journal of cancer

authors： Watanabe K,Emoto N,Hamano E,Sunohara M,Kawakami M,Kage H,Kitano K,Nakajima J,Goto A,Fukayama M,Nagase T,Yatomi Y,Ohishi N,Takai D

更新日期：2012-06-01 00:00:00

abstract：:TK is a pyrimidine metabolic pathway enzyme involved in salvage DNA synthesis. What roles TK may play in epithelial ovarian cancer and the relationships between TK and the other pyrimidine pathway enzymes remain unclear. We examined TK1 gene expression by RT-PCR and related it to gene expression of TS, TP and DPD in 6...

journal_title：International journal of cancer

authors： Fujiwaki R,Hata K,Nakayama K,Moriyama M,Iwanari O,Katabuchi H,Okamura H,Sakai E,Miyazaki K

更新日期：2002-05-20 00:00:00

abstract：:Herein, we show that γδT, CD8(+) αβT lymphocytes and natural killer (NK) cells display a different sensitivity to survival signals delivered via NKG2D surface receptor. All the three effector cell populations activate Akt1/PKBalpha through the engagement of this molecule. Upon binding to leukemic cells expressing NKG2...

journal_title：International journal of cancer

authors： Poggi A,Zancolli M,Boero S,Catellani S,Musso A,Zocchi MR

更新日期：2011-07-15 00:00:00

abstract：:Expression of sialyl Lewis(x) (sLe(x)) and sLe(a) on tumor cells is thought to facilitate metastasis by promoting cell adhesion to selectins on vascular endothelial cells. Experiments supporting this concept usually bypass the early steps of the metastatic process by employing tumor cells that are injected directly in...

journal_title：International journal of cancer

authors： Monzavi-Karbassi B,Whitehead TL,Jousheghany F,Artaud C,Hennings L,Shaaf S,Slaughter A,Korourian S,Kelly T,Blaszczyk-Thurin M,Kieber-Emmons T

更新日期：2005-11-10 00:00:00

abstract：:The annual incidence of non-Hodgkin's lymphomas is increasing by 3 to 4% in different parts of the developed world, while rates for Hodgkin's disease, myelomas and leukemias are more stable. In the case of this group of malignancies, hypothesis generation on risk factors has been limited by the use of the ICD classifi...

journal_title：International journal of cancer

authors： Masala G,Di Lollo S,Picoco C,Crosignani P,Demicheli V,Fontana A,Funtó I,Miligi L,Nanni O,Papucci A,Ramazzotti V,Rodella S,Stagnaro E,Tumino R,Viganó C,Vindigni C,Seniori Costantini A,Vineis P

更新日期：1996-10-09 00:00:00

abstract：:Invasiveness is one of the key features of aggressive prostate cancer; however, our understanding of the precise mechanisms effecting invasion remains limited. The ceramide hydrolyzing enzyme acid ceramidase (AC), overexpressed in most prostate tumors, causes an aggressive and invasive phenotype through downstream eff...

journal_title：International journal of cancer

authors： Beckham TH,Lu P,Cheng JC,Zhao D,Turner LS,Zhang X,Hoffman S,Armeson KE,Liu A,Marrison T,Hannun YA,Liu X

更新日期：2012-11-01 00:00:00

abstract：:Peripheral blood mononuclear cells of most normal adults and patients with breast or lung cancer were found to inhibit [3H] thymidine uptake by lymphoid cell lines in a growth inhibition assay. At effector:target cell ratios between 5:1 and 20:1, lung cancer patients and breast cancer patients, when compared to normal...

journal_title：International journal of cancer

authors： Jerrells TR,Dean JH,Richardson G,Cannon GB,Herberman RB

更新日期：1979-06-15 00:00:00

abstract：:The role of age at menarche and at menopause on epithelial ovarian cancer risk was re-assessed in a combined analysis of 3 hospital-based case-control studies conducted in Italy, the United Kingdom and Greece, which produced a total of 1,140 cases and 2,724 controls. In the overall dataset, there was no evidence of an...

journal_title：International journal of cancer

authors： Franceschi S,La Vecchia C,Booth M,Tzonou A,Negri E,Parazzini F,Trichopoulos D,Beral V

更新日期：1991-08-19 00:00:00

abstract：:It is thought that TIL can be activated in vitro by rIL-2 and acquire specific anti-tumor activity. In this study, we investigated this possibility, using lymphocytes isolated from primary lung cancer tissues. In a first series of experiments, TILs and autologous PBLs from 16 patients were cultured in rIL-2 from 7 to ...

journal_title：International journal of cancer

authors： Yano T,Yasumoto K,Togami M,Ishida T,Kimura G,Sugimachi K,Nomoto K

更新日期：1989-04-15 00:00:00

abstract：:Limited penetration of anticancer drugs through tumour tissue is an important factor that may limit therapeutic effects against solid tumours. Here we report studies of the penetration of radiolabelled methotrexate through multicellular layers (MCL) of murine EMT-6 and human MCF-7 cells grown on semiporous teflon memb...

journal_title：International journal of cancer

authors： Cowan DS,Tannock IF

更新日期：2001-01-01 00:00:00

abstract：:The age-standardized mortality rates for malignant melanoma of the skin in immigrants to New Zealand were compared with those of New Zealand-born non-Maoris. Immigrants from European countries had mortality rates that were generally similar to those prevailing in their countries of origin, although, among immigrants f...

journal_title：International journal of cancer

authors： Cooke KR,Fraser J

更新日期：1985-08-15 00:00:00

abstract：:The results of a survey of a population with a high incidence of oral and oesophageal cancer are presented. The population under study appears to have several epidemiologic characteristics, some of which may be associated with a high incidence of oral and oesophageal cancer. A remarkably high proportion (41%) of the m...

journal_title：International journal of cancer

authors： Zaridze DG,Blettner M,Trapeznikov NN,Kuvshinov JP,Matiakin EG,Poljakov BP,Poddubni BK,Parshikova SM,Rottenberg VI,Chamrakulov FS

更新日期：1985-08-15 00:00:00

abstract：:Examination of the effect of the farnesylprotein transferase (FPTase) inhibitor UCF1-C/manumycin on NIH3T3 cells transfected with a normal N-ras gene and expressing high levels of the corresponding p21-ras protein showed that 10 microm UCF1-C immediately and reversibly inhibited growth in these cells, without modifyin...

journal_title：International journal of cancer

authors： Servais P,Gulbis B,Fokan D,Galand P

更新日期：1998-05-18 00:00:00

abstract：:Data from a hospital-based matched case-control study with 531 male pairs were analyzed for risks of cancer of the lower urinary tract associated with previous employment and particular occupational exposures. Statistically significant odds ratios were obtained for ever-employment as mining workers (2.0), turners (2.3...

journal_title：International journal of cancer

authors： Claude JC,Frentzel-Beyme RR,Kunze E

更新日期：1988-03-15 00:00:00

abstract：:This is a prospective study of lymphoid tissue showing benign reactive hyperplasia (18 lymph nodes and 2 tonsils), using cytogenetic analysis of cells stimulated with T- or B-cell mitogens. The reason for this study was the detection of an abnormal chromosomal population in cells from an enlarged lymph node excised fr...

journal_title：International journal of cancer

authors： Grace J,Hall BE,Lew M,Singh S,Pittman S,Palmer AA,Zbroja R,Wass J,Vincent PC

更新日期：1989-12-15 00:00:00

abstract：:Chemotherapy is a well-established risk factor for acute myeloid leukemia (AML) but little is known about other prescription drugs and AML risk. We report data from a population-based Los Angeles County study in which 299 matched case-control pairs had complete data on prescription drug use and 88% of cases were subty...

journal_title：International journal of cancer

authors： Pogoda JM,Katz J,McKean-Cowdin R,Nichols PW,Ross RK,Preston-Martin S

更新日期：2005-04-20 00:00:00

abstract：:9-cis-Retinoic acid (9cRA) and 1alpha,25-dihydroxyvitamin D3 (1,25D) show promise as potential chemopreventive agents. We examined 9cRA and 1,25D, alone and in combination, for their potential to inhibit carcinogen (NNK)-induced lung carcinogenesis in A/J mice. A/J mice (n=14/group) were treated with 9cRA (7.5, 15, or...

journal_title：International journal of cancer

authors： Mernitz H,Smith DE,Wood RJ,Russell RM,Wang XD

更新日期：2007-04-01 00:00:00

abstract：:We previously reported that ganglioside GD1a, which is highly expressed in poorly metastatic FBJ-S1 cells, inhibits the serum-induced motility of FBJ-LL cells and that the metastatic potential of FBJ-LL cells is completely suppressed by enforced GD1a expression (Hyuga et al., Int J Cancer 1999;83:685-91). We recently ...

journal_title：International journal of cancer

authors： Hyuga S,Kawasaki N,Hyuga M,Ohta M,Shibayama R,Kawanishi T,Yamagata S,Yamagata T,Hayakawa T

更新日期：2001-11-01 00:00:00

abstract：:We have used differential-display PCR (DD-PCR) to compare renal-cell carcinoma (RCC) and normal kidney gene expression with the aim of identifying genes specifically associated with RCC. Using a modified DD-PCR approach, which was non-radioactive, quicker and simpler than the conventional method, 24 cDNA samples were ...

journal_title：International journal of cancer

authors： Rae FK,Stephenson SA,Nicol DL,Clements JA

更新日期：2000-12-01 00:00:00

abstract：:We have previously reported that the negative signaling regulator Similar Expression to FGF (hSef) is downregulated in prostate cancer and its loss is associated with clinical metastasis. Here, we explored the mechanistic basis of this finding. We first confirmed our clinical observation by testing hSef manipulation i...

journal_title：International journal of cancer

authors： Hori S,Wadhwa K,Pisupati V,Zecchini V,Ramos-Montoya A,Warren AY,Neal DE,Gnanapragasam VJ

更新日期：2017-04-15 00:00:00

abstract：:In combination with xenogeneic immune RNA (l-RNA) and tumor antigen (TA), syngeneic spleen cells inhibited the growth of a N-methyl-N-nitrosourethane-induced colon carcinoma (CT-26) in BALB/c mice. The sequential administration of 1 X 10(7) spleen cells, l mg of anti-CT-26 l-RNA and 0.4 mg of CT-26 TA resulted in a 20...

journal_title：International journal of cancer

authors： Fukushima M,Colmerauer ME,Nayak SK,Koziol JA,Pilch YH

更新日期：1982-01-15 00:00:00