Comparative regression analysis of concurrent elimination-phase blood and breath alcohol concentration measurements to determine hourly degradation rates.

Abstract:

:Following the introduction of limit values for blood alcohol and breath alcohol concentrations of 0.5 g/kg and 0.25 mg/L, respectively, as provided under s. 24 a of the German Road Traffic Act the question is whether also breath alcohol concentrations can be back calculated to the time of the traffic offence in cases where it is definite that the person to be examined is in the period of alcohol elimination. To this end, a study was performed in which 56 healthy volunteers consumed 0.5, 0.8 and 1.0 g of ethanol mixed with fruit juice per kilogram of body weight over a period of 10-20 min. Calculations included all 391 pairs of concurrent blood alcohol and breath alcohol concentration values obtained after 2 h following the end of drinking. All volunteers exceeded the peak value of the alcohol curve. The measured values included were above 0.1 g/kg and 0.05 mg/L. For an average intake of alcohol of 0.88 g/kg the following regression lines were calculated for the period starting 2 h after the end of drinking: blood alcohol concentration [g/kg] = 1.318 - 0.172 h and breath alcohol concentration [mg/L] = 0.589 - 0.079 h. Subtracting the simple standard deviation from the mean value yielded hourly degradation rates above 0.1 g/kg and above 0.05 mg/L, respectively. Subtracting two standard deviations, the values fell below this level in both cases. In fact, back calculation of breath alcohol concentrations based on 0.05 mg/h seems to be possible for traffic offences if certain conditions are complied with, such as the use of Evidential 7110, a calibrated breath alcohol analyser approved by the Federal Physical-Technical Laboratory for measuring the breath alcohol concentration.

journal_name

Forensic Sci Int

authors

Jachau K,Sauer S,Krause D,Wittig H

doi

10.1016/j.forsciint.2004.03.023

keywords:

subject

Has Abstract

pub_date

2004-07-16 00:00:00

pages

115-20

issue

2-3

eissn

0379-0738

issn

1872-6283

pii

S037907380400204X

journal_volume

143

pub_type

杂志文章
  • Age estimation standards for a Western Australian population using the coronal pulp cavity index.

    abstract::Age estimation is a vital aspect in creating a biological profile and aids investigators by narrowing down potentially matching identities from the available pool. In addition to routine casework, in the present global political scenario, age estimation in living individuals is required in cases of refugees, asylum se...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2013.04.004

    authors: Karkhanis S,Mack P,Franklin D

    更新日期:2013-09-10 00:00:00

  • Electrochemiluminescent detection of methamphetamine and amphetamine.

    abstract::Direct detection of amphetamine type stimulants (ATSs) including methylamphetamine (MA) in street samples and biological matrices without the need for pretreatment or extraction is a great challenge for forensic drug analysis. Electrochemical techniques, such as electrochemiluminescence (ECL), are promising tools for ...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2016.02.048

    authors: McGeehan J,Dennany L

    更新日期:2016-07-01 00:00:00

  • Challenges in the identification of new thermolabile psychoactive substances: The 25I-NBOH case.

    abstract::The continuous emergence of NPS over the last years poses a series of novel challenges for forensic analysts. Most of those new compounds are synthesized with minimal chemical modifications to the structure of already known chemicals in order to avoid regulations. Some of these new compounds may undergo chemical chang...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2020.110306

    authors: Belchior de Andrade AF,Elie M,Weck C,Jardim Zacca J,de Souza MP,Caldas LNB,Gonzalez-Rodriguez J

    更新日期:2020-07-01 00:00:00

  • Determining vehicle pre-crash speed in frontal barrier crashes using artificial neural network for intermediate car class.

    abstract::This paper introduces a new, innovative approach to pre-crash velocity determination, namely the artificial neural networks. A perceptron based on a database obtained from NHTSA (National Highway Traffic Safety Administration) with numerous data concerning frontal vehicle crash tests: i.e. vehicle mass, deformation zo...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2020.110179

    authors: Mrowicki A,Krukowski M,Turoboś F,Kubiak P

    更新日期:2020-03-01 00:00:00

  • An anatomical and photographic technique for forensic facial identification.

    abstract::The increase in the use of photographs on individual identification credentials such as driving licences, credit cards, security passes and passports has led, for the purpose of criminal activities, to the falsification of genuine documents bearing photographs of the perpetrating criminal. These photographs may be use...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/s0379-0738(00)00290-5

    authors: Porter G,Doran G

    更新日期:2000-11-13 00:00:00

  • A, B and H group specific substances in human vitreous humor.

    abstract::The presence of A, B and H group specific substances in vitreous humor taken from 105 human corpses was determined. Good agreement was obtained between these group substances and the ABO blood group. The relationship with the secretor type is discussed. ...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/0379-0738(89)90242-9

    authors: Rordorf H,Dimo-Simonin N,Brandt-Casadevall C,Gujer HR

    更新日期:1989-04-01 00:00:00

  • Myocardial Cx43 expression in the cases of sudden death due to dilated cardiomyopathy.

    abstract:PURPOSE:Probing into myocardial connexin (Cx) 43 expression in the cases of sudden death due to dilated cardiomyopathy (DCM) and relationship between Cx43 expression and sudden death. METHOD:Myocardial Cx43 was detected with immunohistochemical staining in the cases of 11 sudden death caused by DCM and 14 cases of con...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2006.06.044

    authors: Chen X,Zhang Y

    更新日期:2006-10-16 00:00:00

  • Brephedrone: A new psychoactive substance seized in Brazil.

    abstract::At the beginning of 2015, sixty-two capsules containing red-brown crystals seized in a historical city in Brazil were sent to this forensic laboratory for drug testing analysis. The material was identified as being Brephedrone, a new psychoactive substance and a bromine synthetic cathinone that is related to serotonin...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2017.04.007

    authors: Machado Y,Coelho Neto J,Barbosa PEN,Lordeiro RA,Alves RB

    更新日期:2017-06-01 00:00:00

  • Raman spectroscopy and microspectrophotometry of reactive dyes on cotton fibres: analysis and detection limits.

    abstract::A collaborative study on Raman spectroscopy and microspectrophotometry (MSP) was carried out by members of the ENFSI (European Network of Forensic Science Institutes) European Fibres Group (EFG) on different dyed cotton fabrics. The detection limits of the two methods were tested on two cotton sets with a dye concentr...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2012.05.025

    authors: Massonnet G,Buzzini P,Monard F,Jochem G,Fido L,Bell S,Stauber M,Coyle T,Roux C,Hemmings J,Leijenhorst H,Van Zanten Z,Wiggins K,Smith C,Chabli S,Sauneuf T,Rosengarten A,Meile C,Ketterer S,Blumer A

    更新日期:2012-10-10 00:00:00

  • Toenails as an alternative source material for the extraction of DNA from decomposed human remains.

    abstract::The DNA identification of decomposed human remains for coronial investigations at the Victorian Institute of Forensic Medicine routinely requires the retrieval and processing of a bone sample obtained from the deceased. Bone is a difficult sample type to work with as it requires surgical removal from the deceased, ref...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2015.10.025

    authors: Schlenker A,Grimble K,Azim A,Owen R,Hartman D

    更新日期:2016-01-01 00:00:00

  • Single metal deposition versus physical developer: A comparison between two advanced fingermark detection techniques.

    abstract::Single metal deposition (SMD II) is a fingermark detection technique based on the use of colloidal gold. The technique has been simplified and optimised over the years to become more reliable, sensitive and user-friendly. Physical developer (PD) is a well-established detection method based on silver deposition from a ...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2018.10.032

    authors: Moret S,Lee PLT,de la Hunty M,Spindler X,Lennard C,Roux C

    更新日期:2019-01-01 00:00:00

  • GHB in postmortem toxicology. Discrimination between endogenous production from exposure using multiple specimens.

    abstract::Since gamma-hydroxybutyrate (GHB) is present in both blood and urine of the general population as an endogenous compound, toxicologists must be able to discriminate between these endogenous levels and a concentration resulting from exogenous exposure. The implementation of a cut-off concentration must be done cautious...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2004.02.036

    authors: Kintz P,Villain M,Cirimele V,Ludes B

    更新日期:2004-07-16 00:00:00

  • Transmesenteric hernia due to double-loop formation in the small intestine: a fatal case involving a toddler.

    abstract::We report a unique case of transmesenteric hernia resulting in death, which went undiagnosed during a recent hospital visit. The victim was a 2.5-year-old girl who - with the exception of chronic constipation - had no medical history. One night she complained of abdominal pains and was taken to a pediatric hospital wh...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2011.07.048

    authors: Kakimoto Y,Abiru H,Kotani H,Ozeki M,Tsuruyama T,Tamaki K

    更新日期:2012-01-10 00:00:00

  • Brain-death as an anthropological or as a biological concept.

    abstract::In 1968, when the Harvard Committee defined brain-death to characterize irreversible coma, the question of when a doctor might stop resuscitation remained unresolved: brain-death is a safe, but not a sufficient criterion. Furthermore, the committee defined brain-death to be the death of man without any more than pragm...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/0379-0738(94)90388-3

    authors: Wuermeling HB

    更新日期:1994-12-16 00:00:00

  • Postmortem diagnosis of infectious heart diseases: A mystifying cause of Sudden Infant Death.

    abstract::Sudden infant death (SID) is an unresolved problem of high relevance and previous studies have indicated a role of viral heart infections. The diagnosis remains difficult in clinical practice using routine diagnostic tests and must be substantially improved. A prospective study based on post-mortem samples from SID vi...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2016.03.002

    authors: Gaaloul I,Riabi S,Evans M,Hunter T,Huber S,Aouni M

    更新日期:2016-05-01 00:00:00

  • Methamphetamine-related fatalities in forensic autopsy during 5 years in the southern half of Osaka city and surrounding areas.

    abstract::To outline the recent features of methamphetamine-related fatalities from the medico-legal point of view, a retrospective investigation of forensic autopsy cases involving methamphetamine during a 5-year period (1994-1998) in the southern half of Osaka city and surrounding areas (about 1.57 million population) was und...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/s0379-0738(00)00281-4

    authors: Zhu BL,Oritani S,Shimotouge K,Ishida K,Quan L,Fujita MQ,Ogawa M,Maeda H

    更新日期:2000-09-11 00:00:00

  • Multivariate optimization of the denitration reaction of nitrocelluloses for safer determination of their nitrogen content.

    abstract::The nitrogen content is of paramount importance to predict the explosive or non-explosive character of nitrocellulose (NC), and hence its applications. There are still quite a few really effective analytical methodologies allowing its determination, due to great NC molecular complexity. One of the approaches giving ac...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2015.03.001

    authors: Alinat E,Delaunay N,Archer X,Vial J,Gareil P

    更新日期:2015-05-01 00:00:00

  • The role of the forensic pathologist in the investigation of fatal traffic accidents--the Finnish system.

    abstract::In Finland about one-half of the fatal traffic accidents are investigated by special Boards of Inquiry. The cumulating data serves multidisciplinary sciences, juridical and insurance purposes and legislation. The participating physicians benefit from the systematic work of the Boards in many ways. As an example of the...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/0379-0738(78)90004-x

    authors: Karkola K

    更新日期:1978-11-01 00:00:00

  • An investigation into the suitability of some etching reagents to restoring obliterated stamped numbers on cast iron engine blocks of cars.

    abstract::Most of the automotive companies use cast iron for their engine blocks. Restoration of obliterated number on these iron surfaces by chemical etching is known to be quite difficult. Heating of the obliterated surface using oxyacetylene flame is an alternative recovery treatment suggested in literature and used in pract...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2012.07.020

    authors: Abdul Wahab MF,Mohamad Ghani NI,Kuppuswamy R

    更新日期:2012-11-30 00:00:00

  • Genetic population data of 12 STR loci of the PowerPlex Y system in the state of São Paulo population (Southeast of Brazil).

    abstract::Allele frequency distributions and population data for 12 Y-chromosomal short tandem repeats (STRs) included in the PowerPlex Y Systems (Promega) were obtained for a sample of 200 healthy unrelated males living in São Paulo State (Southeast of Brazil). A total of 192 haplotypes were identified, of which 184 were uniqu...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2006.12.018

    authors: Góis CC,Martins JA,Pereira GA,Freschi A,Paneto GG,Alvarenga VL,Cicarelli RM,Hirata MH,Oliveira RN

    更新日期:2008-01-15 00:00:00

  • The quantitative alteration of the DNA content in strangulation marks is an artefact.

    abstract:UNLABELLED:It is frequently difficult to prove the vitality in cases of fatal hanging. Using impulse cytophotometry, Müller et al. (Krim. Forens. Wiss. 44, 1981) reported on possibly vital alterations of the DNA content in five strangulation marks (hypodiploidy). The objective of the present study was to perform a re-e...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/s0379-0738(97)00069-8

    authors: Grellner W,Benecke M

    更新日期:1997-09-19 00:00:00

  • Determination of gamma-hydroxybutyrate (GHB) and its precursors in blood and urine samples: a salting-out approach.

    abstract::Gamma-hydroxybutyrate (GHB) is an increasingly popular drug of abuse that causes stimulation, euphoria, anxiolysis or hypnosis, depending on the dose used. Low doses of the drug are used recreationally, and also implicated in drug-facilitated sexual assaults. Because of the unusually steep dose-response curves, accide...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2007.06.001

    authors: Kankaanpää A,Liukkonen R,Ariniemi K

    更新日期:2007-08-06 00:00:00

  • Non-equilibrium pH gradient electrophoresis (NEPHGE) on ultrathin polyacrylamide gels containing separators: improved erythrocyte phosphoglucomutase (PGM) and esterase D (EsD) diagnosis in red cell lysates and bloodstains.

    abstract::Two rapid and reliable electrophoretic techniques for PGM1 and EsD typing on ultrathin polyacrylamide gels are described. They have been based on non-equilibrium pH gradient electrophoresis and on the addition of chemical spacers (EPPS for PGM1 and HEPES for EsD) to the gel mixture. ...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/0379-0738(89)90197-7

    authors: Destro-Bisol G,Spinella A

    更新日期:1989-07-01 00:00:00

  • Population data on the 11 STR loci in the Upper Silesia (Poland).

    abstract::Allele frequencies, forensic parameters for the 11 STR loci (TH01, TPOX, CSF1PO, D13S317, D7S820, D16S539, VWA, FESFPS, F13A01, F13B and LPL) were determined in a sample of 140-1262 unrelated adults from the Upper Silesia region (Poland). Comparison of allele frequencies for examined STR loci between the Upper Silesia...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2006.01.011

    authors: Raczek E

    更新日期:2007-05-03 00:00:00

  • The immunohistochemical analysis of fibronectin, collagen type III, laminin, and cytokeratin 5 in putrified skin.

    abstract::Fibronectin, collagen type III, laminin, and cytokeratin 5 were visualized in normal skin and in skin showing early or advanced signs of autolytic decomposition to prove whether the immunohistochemical analysis of these antigens can provide useful information for an age-estimation of skin wounds obtained from putrifie...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/0379-0738(93)90247-8

    authors: Betz P,Nerlich A,Wilske J,Tübel J,Penning R,Eisenmenger W

    更新日期:1993-09-01 00:00:00

  • Vulnerabilities of fingerprint reader to fake fingerprints attacks.

    abstract::The purpose of this research is to assess the vulnerabilities of a high resolution fingerprint sensor when confronted with fake fingerprints. The study has not been focused on the decision outcome of the biometric device, but essentially on the scores obtained following the comparison between a query (genuine or fake)...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2010.05.002

    authors: Espinoza M,Champod C,Margot P

    更新日期:2011-01-30 00:00:00

  • Optimization of a duplex amplification and sequencing strategy for the HVI/HVII regions of human mitochondrial DNA for forensic casework.

    abstract::A duplex primer set for the amplification of mitochondrial DNA HVI and HVII control regions was evaluated for the optimization of a DNA sequencing protocol suitable for forensic casework. HVI and HVII products, with the absence of non-specific products, could be detected by agarose gel electrophoresis when as little a...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2004.09.128

    authors: Chong MD,Calloway CD,Klein SB,Orrego C,Buoncristiani MR

    更新日期:2005-11-25 00:00:00

  • Insect fauna visiting carrion in Southwest Virginia.

    abstract::Successional patterns of insect fauna on pig carcasses were studied in southwest Virginia. The objective was to identify and qualitatively assess the major taxa of forensic importance in this region. Studies were conducted in spring and summer 2001 and 2002, and fall 2002. Over 50 taxa were collected and identified. P...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2004.06.041

    authors: Tabor KL,Fell RD,Brewster CC

    更新日期:2005-05-28 00:00:00

  • Distribution of venlafaxine and O-desmethylvenlafaxine in a fatal case.

    abstract::Venlafaxine is an extensively used antidepressant drug; it is considered to be quite safe and only a few pure cases of fatal poisoning have been reported. Here we describe a fatal case of venlafaxine self-poisoning including detailed tissue distribution of the drug and its metabolite O-desmethylvenlafaxine and the exa...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2014.07.011

    authors: Vignali C,Morini L,Chen Y,Stramesi C,Groppi A

    更新日期:2014-09-01 00:00:00

  • Genetic profile of the Açores Archipelago population using the new PowerPlex 16 system kit.

    abstract::Allele and haplotype frequencies of 16 chromosome STR loci, 15 of them included in the Kit PowerPlex16 System from Promega were determined in a sample of unrelated males from the Açores Archipelago. All subjects were subjected to an interview in order to make sure that their ancestors belonged to the same island at le...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/s0379-0738(02)00203-7

    authors: Velosa RG,Fernandes AT,Brehm A

    更新日期:2002-09-10 00:00:00