Abstract：
:Sudden infant death (SID) is an unresolved problem of high relevance and previous studies have indicated a role of viral heart infections. The diagnosis remains difficult in clinical practice using routine diagnostic tests and must be substantially improved. A prospective study based on post-mortem samples from SID victims whose heart disease was not clinically recognized was conducted for 4 years in a Tunisian University Hospital. Pediatric cases of unnatural death served as controls. Both SID victims and controls were investigated for possible coxsackievirus-B (CV-B) infection in heart tissue. During the study period, 39 cases with a male predominance (77%) were reported. There was no positive family history of coronary artery disease among the victims. In 35 cases (90%), low birth weight and/or critical development period were reported. All SID victims had complained of mild fever and insomnia for a few days preceding death, which required infectious laboratory investigations marked with an elevated white blood cell count (WBC) and C-reactive protein (CRP). The cardiac biomarkers were also elevated. The histopathological investigations of the heart tissue samples revealed signs of myocardial and pericardial inflammation. Enterovirus was detected by immunohistochemistry (IHC) and PCR from myocardial samples from 6 cases (15.3%) having myocarditis and 3 cases (7.7%) having perimyocarditis. The current study is of great interest and is aimed at urging health professionals to adopt systematically long intensive heart care in infants with underlying vulnerability as well as new diagnostic approaches including histopathology complemented with IHC and molecular pathology.
journal_name
Forensic Sci Intjournal_title
Forensic science internationalauthors
Gaaloul I,Riabi S,Evans M,Hunter T,Huber S,Aouni Mdoi
10.1016/j.forsciint.2016.03.002subject
Has Abstractpub_date
2016-05-01 00:00:00pages
166-72eissn
0379-0738issn
1872-6283pii
S0379-0738(16)30086-Xjournal_volume
262pub_type
杂志文章abstract：:One hundred and seventy nine cases of acute poisoning constituting 1.1% of all admissions to the medical unit over 3 years were analysed. Eighty-three per cent of the patients were under 30 years of age and 72% were males. The common agents were: OP insecticides in 51%, kerosene oil in 12%, rat poison in 8% and drugs ...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/0379-0738(88)90221-6
更新日期：1988-01-01 00:00:00
abstract：:An examination of the organ weights associated with victims of drowning, asphyxiation and trauma was undertaken to determine (a) the effects of asphyxiation compared to a trauma group, and in turn, (b) the effects of drowning compared to an asphyxiation group. Included in the study were 217 drowning deaths, 166 pure a...
journal_title：Forensic science international
pub_type： 更正并重新发布的文章,杂志文章
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更新日期：2003-11-26 00:00:00
abstract：:Organic impurities of methamphetamine may show different patterns by synthesis. In the present study, we tried to find the impurities reflecting the conditions of synthesis by comparing impurity patterns of the methamphetamine samples synthesized by different methods. Sixteen methamphetamine samples were synthesized f...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2006.02.054
更新日期：2006-09-12 00:00:00
abstract：:Fibronectin, collagen type III, laminin, and cytokeratin 5 were visualized in normal skin and in skin showing early or advanced signs of autolytic decomposition to prove whether the immunohistochemical analysis of these antigens can provide useful information for an age-estimation of skin wounds obtained from putrifie...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/0379-0738(93)90247-8
更新日期：1993-09-01 00:00:00
abstract：:A collaborative study on Raman spectroscopy and microspectrophotometry (MSP) was carried out by members of the ENFSI (European Network of Forensic Science Institutes) European Fibres Group (EFG) on different dyed cotton fabrics. The detection limits of the two methods were tested on two cotton sets with a dye concentr...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2012.05.025
更新日期：2012-10-10 00:00:00
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journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/0379-0738(88)90185-5
更新日期：1988-05-01 00:00:00
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journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/s0379-0738(02)00096-8
更新日期：2002-06-25 00:00:00
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journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2005.02.016
更新日期：2005-07-16 00:00:00
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journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2009.09.012
更新日期：2009-12-15 00:00:00
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journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2018.08.019
更新日期：2018-10-01 00:00:00
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journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/0379-0738(91)90174-h
更新日期：1991-01-01 00:00:00
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journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/0379-0738(82)90110-4
更新日期：1982-07-01 00:00:00
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journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/s0379-0738(98)00080-2
更新日期：1998-07-06 00:00:00
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journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/s0379-0738(02)00107-x
更新日期：2002-06-25 00:00:00
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journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/s0379-0738(03)00081-1
更新日期：2003-06-24 00:00:00
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journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2012.10.040
更新日期：2013-01-10 00:00:00
abstract：:Leukotriene B4 (LTB4) in skin samples from seven forensic cases was detected by HPLC to distinguish their antemortem or postmortem origin. In total, there were thirteen antemortem and seven postmortem specimens. The results showed that LTB4 was found in all antemortem wound specimens which were either fresh, or refrig...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/0379-0738(96)01938-x
更新日期：1996-07-31 00:00:00
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journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/s0379-0738(01)00490-x
更新日期：2001-11-01 00:00:00
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journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2020.110396
更新日期：2020-09-01 00:00:00
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journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/s0379-0738(02)00086-5
更新日期：2002-05-23 00:00:00
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journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/0379-0738(96)02008-7
更新日期：1996-11-11 00:00:00
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journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2013.04.002
更新日期：2013-06-10 00:00:00
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journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2006.03.037
更新日期：2006-10-16 00:00:00
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journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2007.09.009
更新日期：2008-04-07 00:00:00
abstract：:Tire traces can be observed on several crime scenes as vehicles are often used by criminals. The tread abrasion on the road, while braking or skidding, leads to the production of small rubber particles which can be collected for comparison purposes. This research focused on the statistical comparison of Py-GC/MS profi...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2012.10.013
更新日期：2013-07-10 00:00:00
abstract：:In the early eighties, in response to increasing self-poisoning incidents by pharmaceuticals in Singapore, a comprehensive wide-sweep screen for these drugs in clinical gastric aspirates was devised and implemented by us. The toxicological screen which involved quadruplicate extractions, two in acidic conditions and t...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/0379-0738(92)90158-s
更新日期：1992-05-01 00:00:00
abstract：:Fungi colonizing cadavers are capable of drug metabolism and may thus change the metabolite pattern or concentration of drugs in forensic postmortem samples. The purpose of this study was to check for the presence of such changes by searching fungi-specific metabolites of four model drugs (amitriptyline, metoprolol, m...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2016.03.006
更新日期：2016-05-01 00:00:00
abstract：:Chemical and physicochemical examinations of the fragments of an Egyptian mummy dated between the 3rd and 1st century B.C. were performed. The chemical examinations indicated the presence of resin in the skull and in the fragments of bandages wrapped around the mummy. An analysis of the infrared spectra of the fragmen...
journal_title：Forensic science international
pub_type： 历史文章,杂志文章
doi：10.1016/s0379-0738(98)00192-3
更新日期：1999-01-25 00:00:00
abstract：:Highly efficient multifunctional agarose SERS test stripes has been fabricated by a convenient facile approach. SERS stripes were found to be highly sensitive, robust, and capable to alleviate the two major drawbacks of filter paper based SERS substrate i.e. the weak adhesion of plasmonic nanoparticles and the diffusi...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2014.01.019
更新日期：2014-04-01 00:00:00
abstract：:The detection and identification of volatile compounds is essential to the successful undertaking of numerous forensic analyses. Biological olfactory systems possess the extraordinary ability to not only detect many thousands of distinct volatile compounds (odors) but also to discriminate between them. Whole-organism ...
journal_title：Forensic science international
pub_type： 杂志文章,评审
doi：10.1016/j.forsciint.2013.07.004
更新日期：2013-10-10 00:00:00
