Abstract：
:Direct detection of amphetamine type stimulants (ATSs) including methylamphetamine (MA) in street samples and biological matrices without the need for pretreatment or extraction is a great challenge for forensic drug analysis. Electrochemical techniques, such as electrochemiluminescence (ECL), are promising tools for this area of analysis. This contribution focuses on the electrochemical and photochemical properties of [Ru(bpy)3](2+) Nafion composite films and their subsequent use for the detection of ATS in particular MA. Under optimised conditions, the response linearly increased with the concentration over the concentration range 50pM≤[MA]≤1mM while an equivalent dynamic range was obtained for amphetamine with a correlation coefficient of 0.9903 and 0.9948 respectively. The ECL signal was monitored at ∼620nm, representing the λmax for the [Ru(bpy)3](2+) Nafion composite films. This wavelength is shifted by approximately 15nm compared to the photoexcited λmax for the same system. The modified films were formed by direct interaction with the electrode surface without the need for surface modification or chain linkers. This is a major advantage for the fabrication of any sensor as it reduces the synthesis times resulting in more economically and cheaper production costs. This technique is simple, rapid, selective and sensitive, and shows potential for the high-throughput quantitation of ATS as well as possibilities for adaptation with other techniques such as FIA or LC systems.
journal_name
Forensic Sci Intjournal_title
Forensic science internationalauthors
McGeehan J,Dennany Ldoi
10.1016/j.forsciint.2016.02.048subject
Has Abstractpub_date
2016-07-01 00:00:00pages
1-6eissn
0379-0738issn
1872-6283pii
S0379-0738(16)30070-6journal_volume
264pub_type
杂志文章abstract：:In this paper, we describe an acetylating method for fast synthesis of heroin from morphine in the presence of 4-dimethylaminopyridine (4-DMAP) as a catalyst. In the reaction which led to heroin formation, the morphine base was subjected to a solution made up of 4-DMAP (catalyst), methylene chloride (solvent) and acet...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/s0379-0738(02)00291-8
更新日期：2002-10-09 00:00:00
abstract：:Determination of the synthetic route in methamphetamine profiling relies on the identification of key, route specific marker impurity compounds. Impurity profiling of recent crystalline methamphetamine ('ice'), seized by the Australian Federal Police at the Australian border in 2003-2004, identified route specific mar...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2006.08.016
更新日期：2007-07-04 00:00:00
abstract：:An ingestion of an unknown quantity of U 46 D-Fluid (500 g dichlorophenoxyacetic acid/l) in a suicide is described. Although 2,4-dichlorophenoxyacetic acid (2,4 D) is widely used as a herbicide, intoxications are relatively rare. Quantitation of 2,4-D was performed by diethyl ether extraction from acidified samples (v...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/0379-0738(94)90295-x
更新日期：1994-03-01 00:00:00
abstract：:An arson suspect's contact with an ignitable liquid container can leave small traces of the substance on his hands, but detecting these traces is difficult. This research paper presents a method to obtain clear gasoline detection even 3h after hands have been moistened with 50 μL of gasoline using activated charcoal s...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2010.07.031
更新日期：2011-03-20 00:00:00
abstract：:Hypertension is a growing medical concern in the United States. With the number of Americans suffering from hypertension increasing, the use of antihypertensives such as beta-blockers is increasing as well. In fact, three beta-blockers - atenolol, metoprolol and propranolol - were among the 200 most prescribed medicat...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2005.01.001
更新日期：2006-01-27 00:00:00
abstract：:A highly polymorphic sequence structure is reported in the human beta-actin related pseudogene 2 (ACTBP2) (SE33) locus in members of the Taiwanese Han population. A total of 100 unrelated members of the Taiwanese Han population were used in the study. Alleles that shared the same size but differ in their sequence are ...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/s0379-0738(02)00350-x
更新日期：2002-12-04 00:00:00
abstract：:Bloodstain pattern analysts are sometimes called upon to determine the point of origin of a pattern of bloodstains. A derivation of expressions for the uncertainties deltaX and deltaY in the coordinates of the point of origin P(X, Y) of two bloodstains on a surface has recently been published. These uncertainties were...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2005.10.023
更新日期：2006-08-10 00:00:00
abstract：:A case of ruptured septic myocardial infarct with death from cardiac tamponade in an intravenous drug addict with left-sided infective endocarditis and septic coronary artery embolism is described. To the best of our knowledge, there is no previous report of such a case in the literature. Although uncommon, infective ...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/0379-0738(95)01779-i
更新日期：1995-08-28 00:00:00
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journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/0379-0738(88)90152-1
更新日期：1988-02-01 00:00:00
abstract：:Forensic assessment of skeletal material includes age estimation of unknown individuals. When dealing with extremely fragmented human remains that lack macro-features used in age estimation, histological assessment of the skeletal elements can be employed. Historically, microscopic methods for age assessment used by f...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2020.110335
更新日期：2020-08-01 00:00:00
abstract：:The mathematical modeling of the microbial ethanol production under strict anaerobic experimental conditions for some bacterial species has been proposed by our research group as the first approximation to the quantification of the microbial ethanol production in cases where other alcohols were produced simultaneously...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2013.07.021
更新日期：2013-10-10 00:00:00
abstract：:Air bags have been implicated in saving lives and reducing morbidity associated with motor vehicle crashes since their introduction in the mid-1970s. However, there is increasing evidence showing that air bags can be a source of injury and even death in certain circumstances. As the number of air bag-equipped vehicles...
journal_title：Forensic science international
pub_type： 杂志文章,评审
doi：10.1016/s0379-0738(02)00197-4
更新日期：2002-08-28 00:00:00
abstract：:Over the past ten years, there has been a significant increase in the amount of formulations containing anabolic androgenic steroids apprehended worldwide. A considerable amount of these illicit preparations is falsified imposing a series of challenges for the analytical identification of alleged active ingredients du...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2018.12.022
更新日期：2019-03-01 00:00:00
abstract：:This study was undertaken for the purpose of analysing under the aspect of legal medicine, fatal accidents due to train surfing in the local transport system of Berlin (S-Bahn and underground). The period of investigation was from 1989 through 1995, with 41 train surfing accidents, among them 18 with fatal outcome. Ev...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/s0379-0738(98)00064-4
更新日期：1998-06-08 00:00:00
abstract：:A collaborative exercise was carried out by the European DNA Profiling Group (EDNAP) in order to evaluate the distribution of mitochondrial DNA (mtDNA) heteroplasmy amongst the hairs of an individual who displays point heteroplasmy in blood and buccal cells. A second aim of the exercise was to study reproducibility of...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/S0379-0738(03)00181-6
更新日期：2004-02-10 00:00:00
abstract：:Three novel fluorescent dyes were evaluated for the detection of latent fingermarks on different types and colors of adhesive tapes. Compared with the conventional reagents used to reveal latent fingermarks on these surfaces, these new fluorescent dyes have many advantages. They are highly selective to fingermarks, re...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2016.03.053
更新日期：2016-06-01 00:00:00
abstract：:Modifications of cotton and polyester textiles due to shots fired at short range were analyzed with a variable pressure scanning electron microscope (VP-SEM). Different mechanisms of fiber rupture as a function of fiber type and shooting distance were detected, namely fusing, melting, scorching, and mechanical breakag...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2016.12.033
更新日期：2017-03-01 00:00:00
abstract：:Besides alcohol and drugs of abuse, several popular foods contain potentially toxic substances and cases of intoxication after consumption of these foods attract notice of forensic toxicology. This is also true for the case of a 34-year-old woman who was suspected to have suffered lethal acute intoxication from eating...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2009.12.018
更新日期：2010-04-15 00:00:00
abstract：:The aim of our study was to evaluate differences between males and females based on patterns of costal cartilage ossification and also with respect to ageing. We provided diagnosis of ossifications from two files of radiograms. The first group consisted of 1044 chest and abdominal radiograms of patients (537 men and 5...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2009.06.009
更新日期：2009-10-30 00:00:00
abstract：:Tasmanian opium accounts for 25% of the world's legal supply of opium straw, and in 1998-99 sufficient numbers of flower pods (66,013) to manufacture ca 500 kg of heroin were stolen. Whilst the heroin signature program has been developed to determine the origin of heroin from other key producers, no such signature cur...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2007.07.002
更新日期：2008-03-05 00:00:00
abstract：:The livings have responsibilities for the dead; and in particular, civilized societies recognize the need for identity both during life and at death, particularly in circumstances when an unknown body is summoned for medico-legal autopsy. There are numerous tools for identification of an unknown body which includes vi...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2008.10.018
更新日期：2009-01-10 00:00:00
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journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2017.03.015
更新日期：2017-06-01 00:00:00
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journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2016.04.027
更新日期：2016-07-01 00:00:00
abstract：:Continuing instances of ethical misconduct and recent advances in the practice of forensic science, the latter reflected by increased growth and professionalism, along with heightening public scrutiny, require that the profession be clear, current, and forthright about its core values. A way of expressing these values...
journal_title：Forensic science international
pub_type： 杂志文章,评审
doi：10.1016/s0379-0738(01)00645-4
更新日期：2002-02-18 00:00:00
abstract：:This is the first report of an ongoing study of insect succession on carrion carried out in Medellín, Colombia, using pigs (Sus scrofa) as a model to determine the insect sequence over 207 days. During this period, 2314 insects belonging to the following orders and families were collected: Diptera: Calliphoridae, Musc...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/s0379-0738(01)00422-4
更新日期：2001-08-15 00:00:00
abstract：:In this work, a case of deliberate self-poisoning is presented. A 14-year-old girl suddenly died during one of the several hospitalizations. Abdominal computer tomography showed a large number of metallic particles in the large intestine. Analysis of blood and internal organs for mercury and other toxic metals carried...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2014.02.015
更新日期：2014-04-01 00:00:00
abstract：:Two hundred and sixty UK Caucasian individuals have been typed for the STR locus D12S391. Measurements of absolute band shift, relative to an allelic ladder, allowed fragments differing by one base pair to be consistently distinguished. The intermediate alleles typed from such fragments comprised approximately 5% of t...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/s0379-0738(98)00029-2
更新日期：1998-05-11 00:00:00
abstract：:The exposition to heavy metal-rich airborne due to fire practicing has forced to the development of heavy metal-free environmental ammunition primers all over the world. Here we characterize the GSR elements present in the Brazilian lead-free ammunition produced by Companhia Brasileira de Cartuchos (CBC) and commercia...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2007.07.005
更新日期：2008-05-02 00:00:00
abstract：:Cyanoacrylate fuming, rhodamine 6G staining and 532 nm laser light visualization were used to reveal a thirty-year-old fingermark on a plastic bag discovered at a double homicide scene. ...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2019.04.025
更新日期：2019-07-01 00:00:00
abstract：:This study reports on the relationships between the blood alcohol concentration (BAC) and the cause of death - which is of course common knowledge for forensic scientists! Our special aim was to gain unselected data for generalizing conclusions. The blood of 2465 consecutive cases (86% of all 2852 sudden unexpected an...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/0379-0738(91)90098-4
更新日期：1991-12-01 00:00:00
