Abstract:
:Determination of the synthetic route in methamphetamine profiling relies on the identification of key, route specific marker impurity compounds. Impurity profiling of recent crystalline methamphetamine ('ice'), seized by the Australian Federal Police at the Australian border in 2003-2004, identified route specific marker compounds normally associated with two different synthetic approaches in the same samples. Impurities consistent with the ephedrine route included 1,2-dimethyl-3-phenyl aziridine (I), 1,3-dimethyl-2-phenylnaphthalene (VIII) and 1-benzyl-3-methylnaphthalene (IX), alongside N-formylmethamphetamine (V), N,N-di-(beta-phenylisopropyl)amine (XII) and N,N-di-(beta-phenylisopropyl)methylamine (XIII), N-benzoylamphetamine (XIV) and N,N-di-(beta-phenylisopropyl)formamide (XV) commonly associated with the Leuckart route and/or reductive amination. A non-synthetic process related origin of low-level N-formylmethamphetamine is proposed.
journal_name
Forensic Sci Intjournal_title
Forensic science internationalauthors
Qi Y,Evans I,McCluskey Adoi
10.1016/j.forsciint.2006.08.016subject
Has Abstractpub_date
2007-07-04 00:00:00pages
173-80issue
2-3eissn
0379-0738issn
1872-6283pii
S0379-0738(06)00545-7journal_volume
169pub_type
杂志文章abstract::This study describes an innovative application of a well-established method of age determination. The conventional method of aspartic acid racemization (AAR) is based on estimation of the d-l-aspartic acid ratio in slow turnover tissues, such as tooth tissue, to reflect the age of an individual. This method has been r...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2011.05.015
更新日期:2011-10-10 00:00:00
abstract::One of the most important factors for calculating the accumulated degree days (ADD), which is used to estimate the postmortem interval (PMI) is the accurate estimation of the scene temperature after death. As the estimation method used up to now, they applied to the linear regression analysis using the temperature of ...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2020.110196
更新日期:2020-04-01 00:00:00
abstract::A highly polymorphic sequence structure is reported in the human beta-actin related pseudogene 2 (ACTBP2) (SE33) locus in members of the Taiwanese Han population. A total of 100 unrelated members of the Taiwanese Han population were used in the study. Alleles that shared the same size but differ in their sequence are ...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/s0379-0738(02)00350-x
更新日期:2002-12-04 00:00:00
abstract::Molecular analyses in a post-mortem setting are becoming increasingly common, particularly in cases of sudden unexplained death, with the aim of identifying genetic mutations which may be responsible for causing death. In retrospective investigations, the access to suitable autopsy biological samples may be limited, a...
journal_title:Forensic science international
pub_type: 杂志文章,评审
doi:10.1016/j.forsciint.2017.09.020
更新日期:2017-11-01 00:00:00
abstract::An increasing number of drugs of abuse are sold word wide over the internet. Names like "legal highs", "herbal highs" etc. give the impression that these are safe products, although the risk of fatal reactions might be substantial. Leaves from the plant Mitragyna speciosa, contain active compounds like mitragynine and...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2014.10.025
更新日期:2014-12-01 00:00:00
abstract::In 1968, when the Harvard Committee defined brain-death to characterize irreversible coma, the question of when a doctor might stop resuscitation remained unresolved: brain-death is a safe, but not a sufficient criterion. Furthermore, the committee defined brain-death to be the death of man without any more than pragm...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/0379-0738(94)90388-3
更新日期:1994-12-16 00:00:00
abstract::The stability of four target organic explosives [pentaerythritol tetranitrate (PETN), 2,4,6-trinitrotoluene (TNT), hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) and triacetone triperoxide (TATP)] and two inorganic anions (chlorate and nitrate) on polyester-based alcohol wipes and in 60% (v/v) methanol/water extracts, ...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2013.01.037
更新日期:2013-03-10 00:00:00
abstract::Cannabis cultivation in order to produce drugs is forbidden in Switzerland. Thus, law enforcement authorities regularly ask forensic laboratories to determinate cannabis plant's chemotype from seized material in order to ascertain that the plantation is legal or not. As required by the EU official analysis protocol th...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2010.03.034
更新日期:2010-07-15 00:00:00
abstract::A study was performed to acquire urine, serum and oral fluid samples in cases of suspected driving under the influence of drugs of abuse. Oral fluid was collected using a novel sampling/testing device (Dräger DrugTest System). The aim of the study was to evaluate oral fluid and urine as a predictor of blood samples po...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2004.08.002
更新日期:2005-09-10 00:00:00
abstract::This study reports on the relationships between the blood alcohol concentration (BAC) and the cause of death - which is of course common knowledge for forensic scientists! Our special aim was to gain unselected data for generalizing conclusions. The blood of 2465 consecutive cases (86% of all 2852 sudden unexpected an...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/0379-0738(91)90098-4
更新日期:1991-12-01 00:00:00
abstract::A study of the quantities of cocaine on banknotes in general circulation was conducted to investigate regional variations across England and Wales. No meaningful support was found for the proposition that there is regional variation in the quantities of cocaine in banknotes in general circulation in England and Wales....
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2016.10.017
更新日期:2017-01-01 00:00:00
abstract::Continuing instances of ethical misconduct and recent advances in the practice of forensic science, the latter reflected by increased growth and professionalism, along with heightening public scrutiny, require that the profession be clear, current, and forthright about its core values. A way of expressing these values...
journal_title:Forensic science international
pub_type: 杂志文章,评审
doi:10.1016/s0379-0738(01)00645-4
更新日期:2002-02-18 00:00:00
abstract::A 71-year-old man was found dead in a car into which exhaust fumes had been introduced. His wife who was in the same car recovered consciousness following hospitalization. She claimed that they had both attempted suicide by taking a large number of sleeping pills. Autopsy revealed no significant external injuries or m...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/s0379-0738(97)02110-5
更新日期:1997-04-18 00:00:00
abstract:OBJECTIVES:The aim of this study was to evaluate the accuracy and reliability of three commonly used age estimation methods in Thailand: Greulich-Pyle, Tanner-Whitehouse and Fishman. MATERIALS AND METHODS:Three hundred and sixty-five hand and wrist radiographs of 8-20 years old Thai patients were retrospectively colle...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2018.03.045
更新日期:2018-06-01 00:00:00
abstract::With the increasing prevalence of obesity, the use of counterfeit drugs for weight loss is widespread owing to their easy and rapid availability. Since counterfeit weight-loss drugs are not prepared under the rigorous standard of Good Manufacturing Practice (GMP), they pose a risk to public health and cause significan...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2019.109932
更新日期:2019-10-01 00:00:00
abstract::In this follow-up study the collaboration between two research groups from the USA and the Netherlands was continued to expand the framework of chemical attribution for the homemade explosive erythritol tetranitrate (ETN). Isotope ratio mass spectrometry (IRMS) analysis was performed to predict possible links between ...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2020.110344
更新日期:2020-08-01 00:00:00
abstract::This study focused on the frequency of pathological acid gastroesophageal reflux (AGER) on 50 children considered to be at risk for sudden infant death syndrome: that is to say, 30 near misses and 20 subsequent siblings. Four parameters were studied in a 24-h pH metry: (1) The percentage of time spent at pH less than ...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/0379-0738(88)90152-1
更新日期:1988-02-01 00:00:00
abstract::The growth of five variables of the tibia (diaphyseal length, diaphyseal length plus distal epiphysis, condylo-malleolar length, sagittal diameter of the proximal epiphysis, maximum breadth of the distal epiphysis) were analysed using polynomial regression in order to evaluate their significance and capacity for age a...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2011.07.038
更新日期:2012-01-10 00:00:00
abstract::Successional patterns of insect fauna on pig carcasses were studied in southwest Virginia. The objective was to identify and qualitatively assess the major taxa of forensic importance in this region. Studies were conducted in spring and summer 2001 and 2002, and fall 2002. Over 50 taxa were collected and identified. P...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2004.06.041
更新日期:2005-05-28 00:00:00
abstract::An extraction and determination method of most important amphetamine derivatives in serum has been developed. The procedure comprises liquid-liquid extraction with tert-butyl methyl ether of the sample under basic conditions, centrifugation, formation of hydrochloric salts after the separation of organic phase, vacuum...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2006.03.030
更新日期:2006-09-12 00:00:00
abstract::Many document examiners recognize the importance of an individuals 'state of mind' and its effect on handwriting but historically have steered clear of working closely with psychiatrists, linguists, or psychologists in understanding the interaction of nervous impulses and motor responses on the final handwritten produ...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/0379-0738(82)90150-5
更新日期:1982-01-01 00:00:00
abstract::Species identification is a crucial step in forensic anthropological studies. The aim of this study was to determine elemental profiles in bones from four mammal species, to be used for species discrimination. Human, elephant, dog, and dolphin bones were scanned by X-ray fluorescence (XRF); the differences in elementa...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2016.03.056
更新日期:2016-06-01 00:00:00
abstract::This research presents a new software, "Fragmento", for accurate analyses of fragmentary human skeletal remains and facilitation of three-dimensional (3D) fragmentary matching and full bone reconstruction. The framework utilizes the power of statistical bone atlases to create 3D templates for bone matching and to inte...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2017.03.017
更新日期:2017-06-01 00:00:00
abstract::A challenging step in medical, veterinary and forensic entomology casework is the rapid and accurate identification of insects to estimate the period of insect activity (PIA), which usually approximates the post-mortem interval (PMI). The morphological identification of insect evidence is hampered by species similarit...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2014.07.018
更新日期:2014-09-01 00:00:00
abstract::The response to wounds until healing requires the activity of many cell types coordinate in space and time, so that the types of cells in a wound and their localization may be of help to date lesions with respect to death, which would be useful in forensic pathology. Cells reacting to injury include dendritic cells; t...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2014.08.024
更新日期:2014-11-01 00:00:00
abstract::In Japan, recent trends have seen wild silk preferred over cultivated silk because of its texture. Some cases of fraud have occurred where cultivated silk garments are sold as wild silk. Samples from these cases, morphological observation using light microscope and polarized microscope have been conducted in forensic ...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2013.05.004
更新日期:2013-09-10 00:00:00
abstract::A 66-year-old patient with terminal heart insufficiency (NYHA IV) received maximum medical therapy, but was also in need of an implantable-cardioverter-defibrillator (ICD). The ICD functioned flawlessly for the whole duration of implantation. It reverted several ventricular tachycardias with anti-tachycardial pacing a...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/s0379-0738(01)00633-8
更新日期:2002-02-18 00:00:00
abstract::ABO groups were investigated on skin (and muscle), bone and hair specimens from 14 Egyptian mummies dating from the Roman period. Samples were tested by the AE (absorption-elution), MA (mixed agglutination) and HIF (histo-immunofluorescence) methods, in order to evaluate the reliability of each method. For half of the...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/0379-0738(89)90130-8
更新日期:1989-10-01 00:00:00
abstract::Time-of-flight secondary ion mass spectrometry (TOF-SIMS) was utilized to obtain characteristic mass spectra from three different smokeless powders and six different black powder samples. In these mass spectra, peaks indicative of both the organic and inorganic additive constituents in the gunpowders were observed. TO...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2005.02.036
更新日期:2006-04-20 00:00:00
abstract::Usefulness of portable, handheld breath analysers equipped with electrochemical sensor was assessed. Breath- and blood-alcohol concentrations in drunken drivers were taken from 370 expert opinions elaborated at the Institute of Forensic Research between January 1st 2002 and February 28th 2007. The results of second an...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2008.03.002
更新日期:2008-07-04 00:00:00