Abstract:
:Erdheim-Chester disease (ECD) is a disseminated xanthogranulomatous infiltrative disease of unknown etiology due to infiltration of different organs and bones by foamy histiocytes. A 37-year-old male with cerebral and periorbital lesions was diagnosed with this rare disease and was evaluated with magnetic resonance imaging (MRI) and 2-deoxy-2-[(18)F]fluoro-D-glucose (FDG) with positron emission tomography/computed tomography (PET/CT) imaging at baseline and following therapy. FDG-PET imaging allowed accurate evaluation of the extent of the disease at baseline, as well as assessment of response to therapy.
journal_name
Mol Imaging Bioljournal_title
Molecular imaging and biologyauthors
Pereira Neto CC,Roman C,Johnson M,Jagasia M,Martin WH,Delbeke Ddoi
10.1016/j.mibio.2004.01.023keywords:
subject
Has Abstractpub_date
2004-01-01 00:00:00pages
63-7issue
1eissn
1536-1632issn
1860-2002pii
S1536163204000241journal_volume
6pub_type
杂志文章abstract:PURPOSE:This study aims to determine a lumped constant (LC) value that can be applied to the 2-deoxy-2[18F]fluoro-D-glucose positron emission tomography (FDG-PET) study to yield a physiological value of cerebral metabolic rate of glucose (CMR(glc)) in normal brain. PROCEDURES:We developed a more robust method for dete...
journal_title:Molecular imaging and biology
pub_type: 杂志文章
doi:10.1016/s1536-1632(02)00122-1
更新日期:2003-01-01 00:00:00
abstract:PURPOSE:The aim of this study is to evaluate the impact of different scatter correction strategies on quantification of high-resolution research tomograph (HRRT) data for three tracers covering a wide range in kinetic profiles. PROCEDURES:Healthy subjects received dynamic HRRT scans using either (R)-[(11)C]verapamil (...
journal_title:Molecular imaging and biology
pub_type: 杂志文章
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更新日期:2016-08-01 00:00:00
abstract:PURPOSE:Prostate-specific membrane antigen (PSMA) continues to be the hallmark biomarker for prostate cancer as it is expressed on nearly all prostatic tumors. In addition, increased PSMA expression correlates with castration resistance and progression to the metastatic stage of the disease. Recently, we combined both ...
journal_title:Molecular imaging and biology
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更新日期:2020-04-01 00:00:00
abstract:PURPOSE:Increased expression of the αvβ6 integrin correlates with advanced tumor grade and poor clinical outcome, identifying αvβ6 as a prognostic indicator and an attractive target for molecular imaging. This work investigated the ability of a disulfide-stabilized [64Cu]NOTA-αvβ6 cys-diabody to image αvβ6 expression i...
journal_title:Molecular imaging and biology
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更新日期:2018-02-01 00:00:00
abstract:PURPOSE:High-dose (HD) cytosine arabinoside (ara-C) is a major treatment in acute myeloblastic leukemia (AML) that can lead to cerebellar complications, although electroencephalogram, computed tomography, and magnetic resonance imaging remain normal. We conducted a prospective study to evaluate brain perfusion with sin...
journal_title:Molecular imaging and biology
pub_type: 临床试验,杂志文章
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abstract:PURPOSE:The aim of this study was to investigate the longitudinal positron emission tomography (PET) metabolic changes in the elderly. PROCEDURES:Nineteen nondemented subjects (mean Mini-Mental Status Examination 29.4 +/- 0.7 SD) underwent two detailed neuropsychological evaluations and resting 2-deoxy-2-[F-18]fluoro-...
journal_title:Molecular imaging and biology
pub_type: 临床试验,杂志文章
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更新日期:2010-04-01 00:00:00
abstract:PURPOSE:The purpose of this study was to assess the value of the spatial heterogeneity of somatostatin receptor (SSR) volume, quantified as asphericity (ASP), and to predict response to peptide receptor radionuclide therapy (PRRT) in patients with metastatic gastroenteropancreatic neuroendocrine neoplasms (GEP-NEN). P...
journal_title:Molecular imaging and biology
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更新日期:2017-06-01 00:00:00
abstract:PURPOSE:Sensitivity of contrast-enhanced ultrasound (CEUS) to microvascular flow modifications can be limited by intra-injection variability (injected dose, rate, volume). PROCEDURES:To evaluate the effect of injection variability on microvascular flow evaluation, CEUS was compared between controlled and manual inject...
journal_title:Molecular imaging and biology
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更新日期:2016-10-01 00:00:00
abstract::In vivo imaging of the central nervous system (CNS) neuroreceptors in humans began was used in the early 1980s. Now, some twenty years later, the success of radiopharmaceutical imaging is still often one based on empiricism and serendipity. Nevertheless, a number of factors can be identified based on the robot experie...
journal_title:Molecular imaging and biology
pub_type: 杂志文章,评审
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更新日期:2003-11-01 00:00:00
abstract::Morphological imaging techniques are typically used in the anti-cancer drug efficacy evaluation process. However, these techniques can evaluate the therapeutic efficacy only when the tumor shows anatomic changes-usually at later stages, when the therapeutic effects are poor. In contrast, molecular imaging allows nonin...
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pub_type: 杂志文章,评审
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更新日期:2020-12-01 00:00:00
abstract::The article "Pre-therapy Somatostatin Receptor-Based Heterogeneity Predicts Overall Survival in Pancreatic Neuroendocrine Tumor Patients Undergoing Peptide Receptor Radionuclide Therapy," was originally published electronically on the publisher's internet portal without open access. ...
journal_title:Molecular imaging and biology
pub_type: 杂志文章,已发布勘误
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更新日期:2018-12-01 00:00:00
abstract:PURPOSE:Ga-68-labeled prostate-specific membrane antigen (PSMA) ligands have been used clinically for positron emission tomography (PET) imaging of prostate cancer. However, F-18-labeled compounds offer several advantages, including the potential for delayed imaging, high starting activities enabling multidose preparat...
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更新日期:2015-12-01 00:00:00
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journal_title:Molecular imaging and biology
pub_type: 杂志文章
doi:10.1007/s11307-019-01338-1
更新日期:2019-12-01 00:00:00
abstract:PURPOSE:To explore a representative hypoxic parameter to predict the treatment response and prognosis for [18F]fluoromisonidazole ([18F]FMISO) positron emission tomography (PET)/X-ray computed tomography (CT) in patients with non-small cell lung cancer (NSCLC). PROCEDURES:Twenty-nine patients with NSCLC underwent FMIS...
journal_title:Molecular imaging and biology
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doi:10.1007/s11307-018-1190-2
更新日期:2018-12-01 00:00:00
abstract:PURPOSE:This study aimed to test the hypothesis that lung cancer patient-derived circulating microparticles (LCC-MPs) enhance metastatic lung tumors in a rat model. PROCEDURES:The controls (n = 6) and LCC-MP-treated rats (n = 6) with N1S1-induced pulmonary metastatic hepatocellular carcinoma (HCC) underwent dual-sourc...
journal_title:Molecular imaging and biology
pub_type: 杂志文章
doi:10.1007/s11307-015-0923-8
更新日期:2016-08-01 00:00:00
abstract::Herpes simplex virus (HSV) oncolytic gene therapy is a promising treatment modality against cancer. We have demonstrated that androgen-induced cellular changes enhance oncolytic viral replication and improve efficacy in the treatment of androgen-dependent prostate cancer cell line. Imaging of changes in 2-deoxy-2-[F-1...
journal_title:Molecular imaging and biology
pub_type: 杂志文章
doi:10.1007/s11307-005-0028-x
更新日期:2006-01-01 00:00:00
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pub_type: 杂志文章
doi:10.1007/s11307-014-0719-2
更新日期:2014-08-01 00:00:00
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pub_type: 临床试验,杂志文章
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更新日期:2010-01-01 00:00:00
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更新日期:2019-12-01 00:00:00
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更新日期:2019-08-01 00:00:00
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更新日期:2017-02-01 00:00:00
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更新日期:2016-04-01 00:00:00
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更新日期:2020-06-01 00:00:00
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journal_title:Molecular imaging and biology
pub_type: 杂志文章
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更新日期:2002-03-01 00:00:00
abstract::The blood flow through normal liver parenchyma and a pathologically proven hepatic region of focal nodular hyperplasia (FNH) of the lateral lobe, was measured in a single patient in a quantitative manner using regional dynamic positron emission tomography (PET) imaging with O-15 carbon dioxide (steady state) and O-15 ...
journal_title:Molecular imaging and biology
pub_type: 杂志文章
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更新日期:2002-05-01 00:00:00
abstract:PURPOSE:Recent studies have shown rapid accumulation of nanobodies (NBs) in tumors and fast clearance of the unbound fraction, making NBs exceptional tracers for cancer imaging. In this study, we investigate the combination of in vitro imaging of tumor spheroids, in vivo dual-isotope single-photon emission computed tom...
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更新日期:2019-12-01 00:00:00
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更新日期:2018-06-01 00:00:00
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更新日期:2020-10-27 00:00:00
abstract:PURPOSE:Radioimmunotherapy uses tumor-specific antibodies to deliver therapeutic radionuclides, but hematological toxicity due to the long serum half-life of intact antibodies remains a challenge. We evaluated a smaller antibody fragment, the minibody, with faster kinetics and a potentially improved therapeutic index. ...
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更新日期:2020-10-01 00:00:00
abstract:PURPOSE:To evaluate the clinical significance of differences in 2-deoxy-2-[18F]fluoro-D-glucose positron emission tomography (FDG-PET) lymph node standardized uptake values (SUV) in human immunodeficiency virus (HIV) infection using iterative reconstruction with segmented attenuation correction (IR SAC) compared to fil...
journal_title:Molecular imaging and biology
pub_type: 杂志文章
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更新日期:2002-07-01 00:00:00