In Vivo MR Imaging of Dual MRI Reporter Genes and Deltex-1 Gene-modified Human Mesenchymal Stem Cells in the Treatment of Closed Penile Fracture.

abstract：PURPOSE:The vesicular acetylcholine transporter (VAChT) is a specific biomarker for imaging presynaptic cholinergic neurons. The syntheses and C-11 labeling of two potent enantiopure VAChT inhibitors are reported here. PROCEDURES:Two VAChT inhibitors, (±)-2 and (±)-6, were successfully synthesized. A chiral HPLC colum...

journal_title：Molecular imaging and biology

authors： Padakanti PK,Zhang X,Li J,Parsons SM,Perlmutter JS,Tu Z

更新日期：2014-12-01 00:00:00

abstract：PURPOSE:This study was undertaken to evaluate radiation dosimetry for the prostate-specific membrane antigen targeted [68Ga]Ga-P16-093 radiopharmaceutical, and to initially assess agent performance in positron emission tomography (PET) detection of the site of disease in prostate cancer patients presenting with biochem...

journal_title：Molecular imaging and biology

authors： Green MA,Hutchins GD,Bahler CD,Tann M,Mathias CJ,Territo W,Sims J,Polson H,Alexoff D,Eckelman WC,Kung HF,Fletcher JW

更新日期：2020-06-01 00:00:00

abstract：PURPOSE:To evaluate prognostic value of pretreatment and posttreatment 2-deoxy-2-[18F]fluoro-D-glucose positron emission tomography (FDG-PET) in advanced hypopharyngeal carcinoma treated by chemoradiotherapy. PROCEDURES:Thirty-one patients underwent a baseline FDG-PET and then FDG-PET was repeated 7 weeks after chemor...

journal_title：Molecular imaging and biology

authors： Inohara H,Enomoto K,Tomiyama Y,Higuchi I,Inoue T,Hatazawa J

更新日期：2010-01-01 00:00:00

abstract：PURPOSE:The transplantation of pancreatic islets is a promising cell replacement therapy for type 1 diabetes. Subcutaneous islet transplantation is currently under investigation as a means to circumvent problems associated with standard intra-hepatic islet transplantation. As modifications are being developed to improv...

journal_title：Molecular imaging and biology

authors： Komatsu H,Gonzalez N,Ortiz J,Rawson J,Omori K,Kandeel F,Mullen Y

更新日期：2020-11-02 00:00:00

abstract：PURPOSE:Non-specific extracellular contrast agents have been on the market for more than 15 years. Here, we report on the synthesis of new selective lectin-gadolinium (Gd)-loaded chitosan nanoparticles with a prolonged clearance time and a much higher relaxivity in comparison to other preparations. PROCEDURES:Chitosan...

journal_title：Molecular imaging and biology

authors： Pashkunova-Martic I,Kremser C,Galanski M,Arion V,Debbage P,Jaschke W,Keppler B

更新日期：2011-02-01 00:00:00

abstract：PURPOSE:To demonstrate the efficacy of repeated, non-invasive optical imaging of reporter gene expression in monitoring the ability of bi-specific recombinant molecules (i) to "transductionally untarget" adenovirus from Coxsackie and Adenovirus Receptor (CAR)-dependent infection of normal tissue and (ii) to "transducti...

journal_title：Molecular imaging and biology

authors： Liang Q,Yamamoto M,Curiel DT,Herschman HR

更新日期：2004-11-01 00:00:00

abstract：PURPOSE:To evaluate the clinical significance of differences in 2-deoxy-2-[18F]fluoro-D-glucose positron emission tomography (FDG-PET) lymph node standardized uptake values (SUV) in human immunodeficiency virus (HIV) infection using iterative reconstruction with segmented attenuation correction (IR SAC) compared to fil...

journal_title：Molecular imaging and biology

authors： Chin BB,Lyengar S,Sabundayo BP,Schwartz D

更新日期：2002-07-01 00:00:00

abstract：PURPOSE:As imaging of the cell surface tetraspan protein epithelial membrane protein-2 (EMP2) expression in malignant tumors may provide important prognostic and predictive diagnostic information, the goal of this study is to determine if antibody fragments to EMP2 may be useful for imaging EMP2 positive tumors. PROCE...

journal_title：Molecular imaging and biology

authors： Fu M,Brewer S,Olafsen T,Wu AM,Gordon LK,Said J,Braun J,Wadehra M

更新日期：2013-02-01 00:00:00

abstract：INTRODUCTION:Technetium (Tc) methylene diphosphonate (MDP) has been the standard method for bone scintigraphy for three decades. (18)F sodium fluoride ((18)F NaF) positron emission tomography (PET)/computed tomography (CT) has better resolution and is considered superior. The role of 2-deoxy-2-[(18)F]fluoro-D-glucose (...

journal_title：Molecular imaging and biology

authors： Iagaru A,Mittra E,Dick DW,Gambhir SS

更新日期：2012-04-01 00:00:00

abstract：PURPOSE:Evaluation of [68Ga]NODAGA-duramycin as a positron emission tomography (PET) tracer of cell death for whole-body detection of chemotherapy-induced organ toxicity. PROCEDURES:Tracer specificity of Ga-68 labeled NODAGA-duramycin was determined in vitro using competitive binding experiments. Organ uptake was anal...

journal_title：Molecular imaging and biology

authors： Rix A,Drude NI,Mrugalla A,Baskaya F,Pak KY,Gray B,Kaiser HJ,Tolba RH,Fiegle E,Lederle W,Mottaghy FM,Kiessling F

更新日期：2020-06-01 00:00:00

abstract：:The cyclooxygenase-2 (COX-2) gene plays a role in a wide variety of normal physiologic pathways and is a major target of pharmacologic intervention in a large number of pathophysiologic contexts, including pain, fever, inflammation, and cancer. Expression of the COX-2 gene is induced in a wide range of cells, in respo...

journal_title：Molecular imaging and biology

authors： Nguyen JT,Machado H,Herschman HR

更新日期：2003-07-01 00:00:00

abstract：PURPOSE:Previous studies has demonstrated the utility of human epidermal growth factor receptor type 2 (HER2) as an attractive target for cancer molecular imaging and therapy. An affibody protein with strong binding affinity for HER2, ZHER2:342, has been reported. Various methods of chelator conjugation for radiolabeli...

journal_title：Molecular imaging and biology

authors： Qi S,Hoppmann S,Xu Y,Cheng Z

更新日期：2019-10-01 00:00:00

abstract：PURPOSE:The purpose of the study was to examine the feasibility of an antibody-carrying targeted-bubble preparation using clinically available phosphatidylserine (PS)-containing perfluorobutane-filled microbubbles for molecular ultrasound imaging. PROCEDURES:Firstly, we examined whether PS on the surface of perfluorob...

journal_title：Molecular imaging and biology

authors： Otani K,Yamahara K

更新日期：2011-04-01 00:00:00

abstract：PURPOSE:Although current therapies for many inflammatory/autoimmune diseases are effective, a significant number of patients still exhibit only partial or negligible responses to therapeutic intervention. Since prolonged use of an inadequate therapy can result in both progressive tissue damage and unnecessary expense, ...

journal_title：Molecular imaging and biology

authors： Kelderhouse LE,Mahalingam S,Low PS

更新日期：2016-04-01 00:00:00

abstract：:This article is about head and neck tumor MR imaging and is not within the scope of two National Institutes of Health grants (R0ICA166171, ROICA228188) erroneously listed. Thus, the authors would like to remove the reference to the NIH grants R01CA166171 and R01CA228188 in this article. ...

journal_title：Molecular imaging and biology

authors： Yu L,Li C,Luo X,Zhou J,Zhang C,Zhang Y,Chen M

更新日期：2020-02-01 00:00:00

abstract：PURPOSE:The aim of this study was to investigate the longitudinal positron emission tomography (PET) metabolic changes in the elderly. PROCEDURES:Nineteen nondemented subjects (mean Mini-Mental Status Examination 29.4 +/- 0.7 SD) underwent two detailed neuropsychological evaluations and resting 2-deoxy-2-[F-18]fluoro-...

journal_title：Molecular imaging and biology

authors： Apostolova LG,Thompson PM,Rogers SA,Dinov ID,Zoumalan C,Steiner CA,Siu E,Green AE,Small GW,Toga AW,Cummings JL,Phelps ME,Silverman DH

更新日期：2010-04-01 00:00:00

abstract：PURPOSE:The purpose of this study was to compare C-13 imaging parameters with hyperpolarized [1-13C]pyruvate with conventional gadolinium (Gd)-based perfusion weighted imaging using an orthotopic xenograft model of human glioblastoma multiforme (GBM). PROCEDURES:C-13 3D magnetic resonance spectroscopic imaging (MRSI) ...

journal_title：Molecular imaging and biology

authors： Park I,Lupo JM,Nelson SJ

更新日期：2019-08-01 00:00:00

abstract：PURPOSE:Non-invasive in vivo positron emission tomography (PET) provides high detection sensitivity in the nano- to picomolar range and in addition to other advantages, the possibility to absolutely quantify the acquired data. The present study focuses on the comparison of transmission data acquired with an X-ray compu...

journal_title：Molecular imaging and biology

authors： Mannheim JG,Schmid AM,Pichler BJ

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVES:Accurate staging of patients with melanoma is vital to guide appropriate treatment. 2-Deoxy-2-[F-18]fluoro-D-glucose (FDG)-positron emission tomography (PET) has been reported to be a sensitive and specific technique for the staging of advanced melanoma, however, few studies provide information regarding its...

journal_title：Molecular imaging and biology

authors： Harris MT,Berlangieri SU,Cebon JS,Davis ID,Scott AM

更新日期：2005-07-01 00:00:00

abstract：PURPOSE:Recent researches have demonstrated the value of using 2-deoxy-2-[18F]fluoro-D-glucose ([18F]FDG) positron emission tomography (PET) imaging to reveal the hypothyroidism-related damages in local brain regions. However, the influence of hypothyroidism on the entire brain network is barely studied. This study foc...

journal_title：Molecular imaging and biology

authors： Wang H,Tan Z,Zheng Q,Yu J

更新日期：2018-10-01 00:00:00

abstract：:Fluorescence molecular imaging (MI) is an important concept in preclinical research that focuses on the visualization of cellular and biological function in a non-invasive fashion to better understand in vivo disease processes and treatment effects. MI differs fundamentally from traditional preclinical imaging strateg...

journal_title：Molecular imaging and biology

authors： Peterson JD

更新日期：2019-08-01 00:00:00

abstract：PURPOSE:This study aims to explore whether 4-(2S,4R)-[18F]fluoroglutamine (4-[18F]FGln) positron emission tomography (PET) imaging is helpful in identifying and monitoring MYCN-amplified neuroblastoma by enhanced glutamine metabolism. PROCEDURES:Cell uptake studies and dynamic small-animal PET studies of 4-[18F]FGln a...

journal_title：Molecular imaging and biology

authors： Li C,Huang S,Guo J,Wang C,Huang Z,Huang R,Liu L,Liang S,Wang H

更新日期：2019-12-01 00:00:00

abstract：PURPOSE:The goal of this study was to determine the specificity of ⁶⁴Cu-CB-TE2A-c(RGDyK) (⁶⁴Cu-RGD) for osteoclast-related diseases, such as Paget's disease or rheumatoid arthritis. PROCEDURES:C57BL/6 mice were treated systemically with osteoprotegerin (OPG) for 15 days or RANKL for 11 days to suppress and stimulate o...

journal_title：Molecular imaging and biology

authors： Zheleznyak A,Wadas TJ,Sherman CD,Wilson JM,Kostenuik PJ,Weilbaecher KN,Anderson CJ

更新日期：2012-08-01 00:00:00

abstract：PURPOSE:The dimeric transmembrane integrin, α(v)β(3), is a well-investigated target by different imaging modalities through suitably labeled arginine-glycine-aspartic acid (RGD) containing peptides. In this study, we labeled four cyclic RGD peptides with or without PEG functional groups: c(RGDfK) (denoted as FK), PEG(3...

journal_title：Molecular imaging and biology

authors： Jacobson O,Zhu L,Niu G,Weiss ID,Szajek LP,Ma Y,Sun X,Yan Y,Kiesewetter DO,Liu S,Chen X

更新日期：2011-12-01 00:00:00

abstract：:This paper demonstrates the application of mutual information based coregistration of radionuclide and magnetic resonance imaging (MRI) in an effort to use multimodality imaging for noninvasive localization of stem cells grafted in the infarcted myocardium in rats. Radionuclide imaging such as single photon emission c...

journal_title：Molecular imaging and biology

authors： Shen D,Liu D,Cao Z,Acton PD,Zhou R

更新日期：2007-01-01 00:00:00

abstract：:In vivo imaging of the central nervous system (CNS) neuroreceptors in humans began was used in the early 1980s. Now, some twenty years later, the success of radiopharmaceutical imaging is still often one based on empiricism and serendipity. Nevertheless, a number of factors can be identified based on the robot experie...

journal_title：Molecular imaging and biology

authors： Wong DF,Pomper MG

更新日期：2003-11-01 00:00:00

abstract：PURPOSE:Many neurological diseases affect small structures in the brain and, as such, reliable visual evaluation and accurate quantification are required. Recent technological developments made the clinical use of hybrid positron emission tomography/magnetic resonance (PET/MR) systems possible, providing both functiona...

journal_title：Molecular imaging and biology

authors： Leemans EL,Kotasidis F,Wissmeyer M,Garibotto V,Zaidi H

更新日期：2015-10-01 00:00:00

abstract：PURPOSE:We quantified the performance of time-domain imaging (TDI) and spectral imaging (SI) for fluorescence imaging of quantum dots (QDs) in three distinct imaging instruments: eXplore Optix (TDI, Advanced Research Technologies Inc.), Maestro (SI, CRi Inc.), and IVIS-Spectrum (SI, Caliper Life Sciences Inc.). PROCED...

journal_title：Molecular imaging and biology

authors： de la Zerda A,Bodapati S,Teed R,Schipper ML,Keren S,Smith BR,Ng JS,Gambhir SS

更新日期：2010-10-01 00:00:00

abstract：PURPOSE:The aim of this study is to generate a four-class magnetic resonance imaging (MRI)-based attenuation map (μ-map) for attenuation correction of positron emission tomography (PET) data of the head area using a novel combination of short echo time (STE)/Dixon-MRI and a dedicated image segmentation method. PROCEDU...

journal_title：Molecular imaging and biology

authors： Khateri P,Saligheh Rad H,Jafari AH,Fathi Kazerooni A,Akbarzadeh A,Shojae Moghadam M,Aryan A,Ghafarian P,Ay MR

更新日期：2015-12-01 00:00:00

abstract：PURPOSE:We examine the feasibility of fluorescent imaging system for sentinel lymph node detection by using functionalized silica nanoparticles. MATERIALS AND METHODS:We developed a functionalized RITC-SiO(2) nanoparticles containing fluorescent dye, C(28)H(31)N(2)O(3)Cl (rhodamine B isothiocyanate) inside, and subseq...

journal_title：Molecular imaging and biology

authors： Jeon YH,Kim YH,Choi K,Piao JY,Quan B,Lee YS,Jeong JM,Chung JK,Lee DS,Lee MC,Lee J,Chung DS,Kang KW

更新日期：2010-04-01 00:00:00