当前位置： SCI文献检索 > EXPERIMENTAL CELL RESEARCH期刊下所有文献 > Growth and differentiation potential of main- and side-population cells derived from murine skeletal muscle.

Growth and differentiation potential of main- and side-population cells derived from murine skeletal muscle.

Abstract：

:Skeletal muscle-derived CD34+/45- (Sk-34) cells were identified as a new candidate for stem cells. However, the relationship between Sk-34 cells and side-population (SP) cells is unknown. Here, we demonstrate that Sk-34 cells prepared from murine skeletal muscles consist wholly of main-population (MP) cells. The Sk-34 cells included only a few SP cells (1:1000, SP:MP). Colony-forming units of Sk-34 cells of both SP and MP possessed the same potential to differentiate into adipocytes, endothelial, and myogenic cells and showed the same colony-forming activity (1.6%). In addition, the colony-forming units of the CD34-/45- (double negative: DN) population were found to begin CD34 expression and to possess the potential to differentiate into myogenic and endothelial cells. We also found that expression of CD34 antigen precedes MyoD expression during the myogenic process of DN cells. Furthermore, both Sk-34 and DN cell populations were mostly negative for CD73 (93-95%), whereas the CD45+ cell population was >25% positive for CD73, and this trend was also seen in bone marrow-derived CD45+ cells. These results indicate that the MP cell population is about 99.9% responsible for the reported in vitro myogenic-endothelial responses of skeletal muscle-derived cells.

journal_name

Exp Cell Res

journal_title

Experimental cell research

authors

Tamaki T,Akatsuka A,Okada Y,Matsuzaki Y,Okano H,Kimura M

doi

10.1016/s0014-4827(03)00376-8

keywords:

subject

Has Abstract

pub_date

2003-11-15 00:00:00

pages

83-90

issue

1

eissn

0014-4827

issn

1090-2422

pii

S0014482703003768

journal_volume

291

pub_type

杂志文章

相关文献

EXPERIMENTAL CELL RESEARCH文献大全
  • Absence of the Shb gene in mixed-lineage leukemia MLL-AF9 cells increases latency in mice despite higher proliferation rates in vitro.

    abstract：:Mixed lineage leukemia (MLL) arises from several KMT2A-gene chromosomal translocations. Shb gene deficiency has been found to exhibit pleiotropic effects in different models of leukemia, and consequently, this study aimed to investigate MLL-AF9-induced leukemia in Shb deficiency. Bone marrow cells from wild type and S...

    journal_title：Experimental cell research

    pub_type： 杂志文章

    doi：10.1016/j.yexcr.2020.112368

    authors： Jamalpour M,Bergquist E,Welsh M

    更新日期：2020-12-15 00:00:00

  • Establishment of a germ-line competent C57BL/6 embryonic stem cell line.

    abstract：:Embryonic stem (ES) cell lines have been derived from blastocysts of the inbred mouse strain C57BL/6. The highest frequencies of ES cell colonies were observed when blastocysts were explanted directly onto growth-arrested feeder layers of 5637 human bladder carcinoma cells in the presence of conditioned medium. One of...

    journal_title：Experimental cell research

    pub_type： 杂志文章

    doi：10.1016/0014-4827(91)90430-3

    authors： Ledermann B,Bürki K

    更新日期：1991-12-01 00:00:00

  • Investigation of the role of G1/S cell cycle mediators in cellular senescence.

    abstract：:Cellular senescence is a state of irreversible cell cycle arrest in which normal cells at the end of their lifespan fail to enter into DNA synthesis upon serum or growth factor stimulation. We examined whether proteins required for G1/S cell cycle progression were irreversibly down-regulated in senescent human fibrobl...

    journal_title：Experimental cell research

    pub_type： 杂志文章

    doi：10.1006/excr.1993.1306

    authors： Afshari CA,Vojta PJ,Annab LA,Futreal PA,Willard TB,Barrett JC

    更新日期：1993-12-01 00:00:00

  • The structural analysis of adhesions mediated by Ep-CAM.

    abstract：:The epithelial cell adhesion molecule Ep-CAM is capable of mediating Ca2+-independent homotypic cell-cell adhesion when introduced into cells lacking their own means of cell-cell interactions. We used (confocal) immunofluorescent and (immuno-) electron microscopy to investigate the structural organization of Ep-CAM-me...

    journal_title：Experimental cell research

    pub_type： 杂志文章

    doi：10.1006/excr.1998.4263

    authors： Balzar M,Prins FA,Bakker HA,Fleuren GJ,Warnaar SO,Litvinov SV

    更新日期：1999-01-10 00:00:00

  • Variation and frequency of cytokeratin polypeptide patterns in human squamous non-keratinizing epithelium.

    abstract：:The squamous non-keratinizing epithelium of the human upper digestive tract was analyzed for keratin-like cytoskeletal proteins (cytokeratins) by both high resolution one- and two-dimensional gel electrophoresis. The Triton/high salt-insoluble portion of pure epithelial homogenates contains a number of SDS- and urea-e...

    journal_title：Experimental cell research

    pub_type： 杂志文章

    doi：10.1016/0014-4827(86)90430-1

    authors： Wild GA,Mischke D

    更新日期：1986-01-01 00:00:00

  • An essential role for Src kinase in ErbB receptor signaling through the MAPK pathway.

    abstract：:ErbB receptor tyrosine kinases are activated by multiple ligands such as epidermal growth factor (EGF) and neuregulins (NRGs), leading to stimulation of intracellular signaling pathways, including the mitogen-activated protein kinase (MAPK) cascade. We show here that Src kinase is essential for rapid EGF- and NRG-indu...

    journal_title：Experimental cell research

    pub_type： 杂志文章

    doi：10.1006/excr.2001.5242

    authors： Olayioye MA,Badache A,Daly JM,Hynes NE

    更新日期：2001-07-01 00:00:00

  • Isolation of cell lines from differentiating embryonal carcinoma cultures.

    abstract：:We report the isolation of six cell lines (designated EB cell lines) from cultures of the hypoxanthine guanine phosphoribosyl transferase-deficient (HGPRT-) feeder-dependent embryonal carcinoma cell line PSA4TG12 which have undergone in vitro differentiation, and of clonal derivatives of these lines. Whereas some line...

    journal_title：Experimental cell research

    pub_type： 杂志文章

    doi：10.1016/0014-4827(83)90167-2

    authors： Morgan RH,Henry JA,Hooper ML

    更新日期：1983-10-15 00:00:00

  • Characterization and response of newly developed high-grade glioma cultures to the tyrosine kinase inhibitors, erlotinib, gefitinib and imatinib.

    abstract：:High-grade gliomas (HGG), are the most common aggressive brain tumours in adults. Inhibitors targeting growth factor signalling pathways in glioma have shown a low clinical response rate. To accurately evaluate response to targeted therapies further in vitro studies are necessary. Growth factor pathway expression usin...

    journal_title：Experimental cell research

    pub_type： 杂志文章

    doi：10.1016/j.yexcr.2012.01.014

    authors： Kinsella P,Howley R,Doolan P,Clarke C,Madden SF,Clynes M,Farrell M,Amberger-Murphy V

    更新日期：2012-03-10 00:00:00

  • Control of apoptosis and growth of malignant T lymphoma cells by lymph node stromal cells.

    abstract：:We have previously established the malignant T lymphoma CS-21 cell line from a spontaneous lymphoma in a BALB/c mouse. CS-21 lymphoma cells grew continuously when they were cocultured with stromal CA-12 cells prepared from lymph nodes. CS-21 lymphoma cells, however, could not proliferate by themselves, and they underw...

    journal_title：Experimental cell research

    pub_type： 杂志文章

    doi：10.1006/excr.1993.1193

    authors： Kataoka S,Naito M,Fujita N,Ishii H,Ishii S,Yamori T,Nakajima M,Tsuruo T

    更新日期：1993-08-01 00:00:00

  • Insulin binds to type V collagen with retention of mitogenic activity.

    abstract：:The abilities of eight extracellular matrix proteins, fibronectin, vitronectin, laminin, and collagen types I, II, III, IV, and V to bind insulin were examined by binding studies with insulin conjugated with peroxidase. At a physiological pH and ionic strength, type V collagen bound to insulin most strongly. The other...

    journal_title：Experimental cell research

    pub_type： 杂志文章

    doi：10.1016/0014-4827(91)90351-t

    authors： Yaoi Y,Hashimoto K,Takahara K,Kato I

    更新日期：1991-06-01 00:00:00

  • p107 and p130: versatile proteins with interesting pockets.

    abstract：:p107 and p130 were originally identified as targets of the transforming domains of viral oncoproteins encoded by small DNA tumor viruses. Together with pRB, the protein product of the retinoblastoma gene (Rb), p107 and p130 represent a family of closely related proteins that play critical roles in the regulation of ce...

    journal_title：Experimental cell research

    pub_type： 杂志文章,评审

    doi：10.1006/excr.2000.5135

    authors： Classon M,Dyson N

    更新日期：2001-03-10 00:00:00

  • Novel approach to abuse the hyperactive K-Ras pathway for adenoviral gene therapy of colorectal cancer.

    abstract：BACKGROUND:Functional activation of oncogenic K-Ras signaling pathway plays an important role in the early events of colorectal carcinogenesis (CRC). K-Ras proto-oncogene is involved in 35-40% of CRC cases. Mutations in the Ras gene trigger the transduction of proliferative and anti-apoptotic signals, even in the absen...

    journal_title：Experimental cell research

    pub_type： 杂志文章

    doi：10.1016/j.yexcr.2011.09.015

    authors： Naumov I,Kazanov D,Lisiansky V,Starr A,Aroch I,Shapira S,Kraus S,Arber N

    更新日期：2012-01-15 00:00:00

  • p120 serine and threonine phosphorylation is controlled by multiple ligand-receptor pathways but not cadherin ligation.

    abstract：:p120-catenin (p120) regulates cadherin turnover and is required for cadherin stability. Extensive and dynamic phosphorylation on tyrosine, serine and threonine residues in the N-terminal regulatory domain has been postulated to regulate p120 function, possibly through modulation of the efficiency of p120/cadherin inte...

    journal_title：Experimental cell research

    pub_type： 杂志文章

    doi：10.1016/j.yexcr.2006.07.007

    authors： Xia X,Carnahan RH,Vaughan MH,Wildenberg GA,Reynolds AB

    更新日期：2006-10-15 00:00:00

  • Recent progress in protocadherin research.

    abstract：:Protocadherins constitute a large family belonging to the cadherin superfamily and function in different tissues of a wide variety of multicellular organisms. Protocadherins have unique features that are not found in classic cadherins. Expression of protocadherins is spatiotemporally regulated and they are localized a...

    journal_title：Experimental cell research

    pub_type： 杂志文章,评审

    doi：10.1006/excr.2000.5039

    authors： Suzuki ST

    更新日期：2000-11-25 00:00:00

  • Zebrafish and Xenopus tadpoles: small animal models to study angiogenesis and lymphangiogenesis.

    abstract：:Small vertebrate organisms have emerged as key players in the post-genomic era for the functional characterization of novel genes on a high-throughput scale. In this context, the zebrafish embryos and Xenopus tadpoles represent attractive and valuable models to rapidly identify and characterize novel genes involved in...

    journal_title：Experimental cell research

    pub_type： 杂志文章,评审

    doi：10.1016/j.yexcr.2005.10.018

    authors： Ny A,Autiero M,Carmeliet P

    更新日期：2006-03-10 00:00:00

  • Sendai virus and herpes virus type 1 induce apoptosis in human peripheral blood mononuclear cells.

    abstract：:Recent reports suggest that several viruses, besides human immunodeficiency virus, induce apoptosis in infected cells. We report here that Sendai virus or Herpes simplex virus type 1 (HSV-1), two potent inducers of interferon-alpha, caused cell death in a consistent number of human peripheral blood mononuclear cells. ...

    journal_title：Experimental cell research

    pub_type： 杂志文章

    doi：10.1006/excr.1995.1131

    authors： Tropea F,Troiano L,Monti D,Lovato E,Malorni W,Rainaldi G,Mattana P,Viscomi G,Ingletti MC,Portolani M

    更新日期：1995-05-01 00:00:00

  • S100P/RAGE signaling regulates microRNA-155 expression via AP-1 activation in colon cancer.

    abstract：:Accumulating evidence indicates that elevated S100P promotes the pathogenesis of cancers, including colon cancer. S100P exerts its effects by binding to and activating the Receptor for Advance Glycation End-products (RAGE). The effects of up-regulated S100P/RAGE signaling on cell functions are well documented. Despite...

    journal_title：Experimental cell research

    pub_type： 杂志文章

    doi：10.1016/j.yexcr.2013.05.009

    authors： Onyeagucha BC,Mercado-Pimentel ME,Hutchison J,Flemington EK,Nelson MA

    更新日期：2013-08-01 00:00:00

  • Cytostatic factor (CSF) activity in cytosols extracted from Xenopus laevis eggs.

    abstract：:Cytostatic factor (CSF), found in the cytoplasm of unfertilized eggs of amphibians, causes metaphase arrest when microinjected into cleaving blastomeres. Although CSF from Rana pipiens eggs has been extracted and characterized, little is known about CSF extracted from eggs of other species. We investigated the conditi...

    journal_title：Experimental cell research

    pub_type： 杂志文章

    doi：10.1016/0014-4827(90)90211-r

    authors： Moses RM,Masui Y

    更新日期：1990-01-01 00:00:00

  • Gene expression profiling in response to the histone deacetylase inhibitor BL1521 in neuroblastoma.

    abstract：:Neuroblastoma is a childhood tumor with a poor survival in advanced stage disease despite intensive chemotherapeutic regimes. The new histone deacetylase (HDAC) inhibitor BL1521 has shown promising results in neuroblastoma. Inhibition of HDAC resulted in a decrease in proliferation and metabolic activity, induction of...

    journal_title：Experimental cell research

    pub_type： 杂志文章

    doi：10.1016/j.yexcr.2005.06.024

    authors： de Ruijter AJ,Meinsma RJ,Bosma P,Kemp S,Caron HN,van Kuilenburg AB

    更新日期：2005-10-01 00:00:00

  • Collective cell migration of primary zebrafish keratocytes.

    abstract：:Fish keratocytes are an established model in single cell motility but little is known about their collective migration. Initially, sheets migrate from the scale at ~145 μm/h but over the course of 24h the rate of leading edge advance decreases to ~23 μm/h. During this period, leader cells retain their ability to migra...

    journal_title：Experimental cell research

    pub_type： 杂志文章

    doi：10.1016/j.yexcr.2014.06.011

    authors： Rapanan JL,Cooper KE,Leyva KJ,Hull EE

    更新日期：2014-08-01 00:00:00

  • Calpain translocation during muscle fiber necrosis and regeneration in dystrophin-deficient mice.

    abstract：:Previous studies have shown that calpains are autolytically cleaved during the disease process of mdx dystrophy, a mouse model for Duchenne muscular dystrophy, indicating that calpains may be activated and play a role in proteolysis that occurs in muscular dystrophy (J. Biol. Chem. 270(18), 10909-10914, 1995). In the ...

    journal_title：Experimental cell research

    pub_type： 杂志文章

    doi：10.1006/excr.1996.0227

    authors： Spencer MJ,Tidball JG

    更新日期：1996-08-01 00:00:00

  • Trichostatin A affects the secretion pathways of beta and intestinal endocrine cells.

    abstract：:Histone deacetylase inhibitors (HDACi) were recently identified as having significant clinical potential in reversing β-cell functional inhibition caused by inflammation, a shared precursor of Type 1 and Type 2 diabetes. However, HDACi are highly complex and little is known of their direct effect on important cell sec...

    journal_title：Experimental cell research

    pub_type： 杂志文章

    doi：10.1016/j.yexcr.2014.09.031

    authors： Tiernan AR,Champion JA,Sambanis A

    更新日期：2015-01-01 00:00:00

  • The recycling of a secretory granule membrane protein.

    abstract：:We have used N-hydroxysuccinimido-d-biotin as a reagent for labeling proteins exposed at the surface of cultured bovine adrenal chromaffin cells during Ba2+-stimulated secretion. A specific secretory granule membrane constituent, dopamine-beta-hydroxylase (DBH), has been investigated using immunoprecipitation followed...

    journal_title：Experimental cell research

    pub_type： 杂志文章

    doi：10.1016/0014-4827(89)90249-8

    authors： Hunter A,Phillips JH

    更新日期：1989-06-01 00:00:00

  • Overexpression of cyclin D1 blocks proliferation of normal diploid fibroblasts.

    abstract：:Human cyclin D1 forms complexes with several Cdks, with proliferating cell nuclear antigen, and with a recently discovered 21-kDa inhibitor of Cdk activity. Substrates for cyclin D1/Cdks have not been identified in vivo, but it has been proposed that the D class of cyclins might play a role in regulating the activity ...

    journal_title：Experimental cell research

    pub_type： 杂志文章

    doi：10.1006/excr.1995.1080

    authors： Atadja P,Wong H,Veillete C,Riabowol K

    更新日期：1995-04-01 00:00:00

  • Liver 'organ on a chip'.

    abstract：:The liver plays critical roles in both homeostasis and pathology. It is the major site of drug metabolism in the body and, as such, a common target for drug-induced toxicity and is susceptible to a wide range of diseases. In contrast to other solid organs, the liver possesses the unique ability to regenerate. The phys...

    journal_title：Experimental cell research

    pub_type： 杂志文章,评审

    doi：10.1016/j.yexcr.2017.12.023

    authors： Beckwitt CH,Clark AM,Wheeler S,Taylor DL,Stolz DB,Griffith L,Wells A

    更新日期：2018-02-01 00:00:00

  • Large macromolecules can be introduced into cultured mammalian cells using erythrocyte membrane vesicles.

    abstract：:Plasmid 6.4 kbp DNA, 14 kbp DNA, lambda phage particles, all of which contained herpes simplex virus type 1 (HSV-1) thymidine kinase (TK) gene, or IgM molecules, were mixed with erythrocyte membranes and treated with neutral detergent. The transparent mixture was diluted with phosphate-buffered saline (PBS), followed ...

    journal_title：Experimental cell research

    pub_type： 杂志文章

    doi：10.1016/s0014-4827(85)80014-8

    authors： Sugawa H,Uchida T,Yoneda Y,Ishiura M,Okada Y

    更新日期：1985-08-01 00:00:00

  • Induction of hyper-adhesion attenuates autoimmune-induced keratinocyte cell-cell detachment and processing of adhesion molecules via mechanisms that involve PKC.

    abstract：:In confluent keratinocyte monolayers, desmosomal adhesion gradually becomes calcium-independent and this is associated with an increase in the strength of intercellular adhesion (hyper-adhesion). In this study, we investigated the functional and molecular significance of hyper-adhesion in a system challenged by autoim...

    journal_title：Experimental cell research

    pub_type： 杂志文章

    doi：10.1016/j.yexcr.2009.10.005

    authors： Cirillo N,Lanza A,Prime SS

    更新日期：2010-02-15 00:00:00

  • Dissecting the sequence specific functions of alternative N-terminal isoforms of mouse bullous pemphigoid antigen 1.

    abstract：:Bullous pemphigoid antigen 1 (BPAG1) is a member of the plakin family of proteins that is involved in cross-linking the cytoskeletal elements and attaching them to cell junctions. BPAG1 null mice develop severe degeneration of sensory neurons that was attributed in part due to the absence of a splice variant called BP...

    journal_title：Experimental cell research

    pub_type： 杂志文章

    doi：10.1016/j.yexcr.2006.04.025

    authors： Jefferson JJ,Leung CL,Liem RK

    更新日期：2006-09-10 00:00:00

  • Involvement of LPA signaling via LPA receptor-2 in the promotion of malignant properties in osteosarcoma cells.

    abstract：:Lysophosphatidic acid (LPA) signaling via G protein-coupled LPA receptors mediates various biological effects in cancer cells. This study aimed to investigate the roles of LPA receptors in the regulation of cellular functions during tumor progression in osteosarcoma cells. Long-term cisplatin (CDDP)-treated MG63-C and...

    journal_title：Experimental cell research

    pub_type： 杂志文章

    doi：10.1016/j.yexcr.2018.05.037

    authors： Takahashi K,Fukushima K,Tanaka K,Minami K,Ishimoto K,Otagaki S,Fukushima N,Honoki K,Tsujiuchi T

    更新日期：2018-08-15 00:00:00

  • The functional domains for Bax∆2 aggregate-mediated caspase 8-dependent cell death.

    abstract：:Bax∆2 is a functional pro-apoptotic Bax isoform having alterations in its N-terminus, but sharing the rest of its sequence with Baxα. Bax∆2 is unable to target mitochondria due to the loss of helix α1. Instead, it forms cytosolic aggregates and activates caspase 8. However, the functional domain(s) responsible for Bax...

    journal_title：Experimental cell research

    pub_type： 杂志文章

    doi：10.1016/j.yexcr.2017.08.016

    authors： Mañas A,Wang S,Nelson A,Li J,Zhao Y,Zhang H,Davis A,Xie B,Maltsev N,Xiang J

    更新日期：2017-10-15 00:00:00