Abstract:
:Scarce published data on the long-term excretion of tritiated water from the human body have been re-evaluated in order to develop a biokinetic model describing the retention in the human body of 3H from tritiated water (HTO) that could be used for both prospective and retrospective radiation protection. A three-component exponential function is proposed to describe the elimination of 3H from HTO with biological half-times of 10 d (99.00%), 40 d (0.98%) and 350 d (0.02%) respectively. The model predicts a committed effective dose of 1.7 x 10(-11) Sv Bq(-1), comparable with that of the current ICRP Publication 56 and 72 models, and estimates the retention of 3H to within a factor of about 2 of the measured values up to 40 d after intake and about 5 at times longer than 100 d. The derivation of the model and the uncertainties associated with the various parameters are discussed.
journal_name
Radiat Prot Dosimetryjournal_title
Radiation protection dosimetryauthors
Taylor DMdoi
10.1093/oxfordjournals.rpd.a006227keywords:
subject
Has Abstractpub_date
2003-01-01 00:00:00pages
225-8issue
1-4eissn
0144-8420issn
1742-3406journal_volume
105pub_type
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