Abstract:
:This study aimed to reveal the effect of X-irradiation on mitochondrial function in terms of mitochondrial membrane potential (ΔΨm) and ATP productivity. At the cellular level, ΔΨm was quantified using JC-1, a mitochondrial probe that emits red or green fluorescence at high or low ΔΨm sites, respectively. The fluorescence area was quantified for both colors together relative to the whole-cell area of the same cell. The fluorescence areas versus whole-cell areas varied widely among the irradiated cells depending on the X-ray doses received (6 and 10 Gy) and incubation time, although the relative red area to total mitochondrial area was rather constant. Average ATP concentrations temporarily increased and showed a maximum at 48 h after irradiation for largely G1-arrested cells. These results indicate that an increase of mitochondrial volume per cell, not simply an increase in their active sites, is induced by irradiation, resulting in enhanced ATP production.
journal_name
Radiat Prot Dosimetryjournal_title
Radiation protection dosimetryauthors
Hamada R,Kaminaga K,Suzuki K,Yokoya Adoi
10.1093/rpd/ncy254subject
Has Abstractpub_date
2019-05-01 00:00:00pages
98-101issue
1-2eissn
0144-8420issn
1742-3406pii
5244128journal_volume
183pub_type
杂志文章abstract::The electrochemical etching (ECE) method enlarges charged particle tracks to enhance its applications in particular in health physics and radiation dosimetry. The ECE method is usually based on using a high frequency-high voltage (HF-HV) generator with 250-µm-thick polycarbonate track detectors (PCTDs). The authors' r...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncu303
更新日期:2015-04-01 00:00:00
abstract::The material for this study comprised control protocols from 248 mammography screening facilities, prepared by physicists employed at 16 Regional Coordinating Centres and the results from the clinical evaluation of mammographic images in 248 facilities in Poland. All mammograms were evaluated independently by three ex...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章,多中心研究
doi:10.1093/rpd/ncr321
更新日期:2011-09-01 00:00:00
abstract::Methodological problems arise on the way of radiation carcinogenesis modelling with the incorporation of radiobiological and cancer biology mechanistic data. The results of biophysical modelling of different endpoints [DNA DSB induction, repair, chromosome aberrations (CA) and cell proliferation] are presented and app...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncl463
更新日期:2006-01-01 00:00:00
abstract::The National Institute of Standards and Technology developed a new set of test sources for testing of portal monitors against the ANSI standard N42.35-2004. The design and source specifications are provided in this work. ...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/nch422
更新日期:2005-01-01 00:00:00
abstract::The objective of this article is to present initial occupational dose values using digital active personal dosimeters for medical staff during adult interventional cardiology procedures in a public hospital in Chile. Personal dose equivalent Hp(10) over the lead apron of physician, nurse and radiographer were measured...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncy057
更新日期:2018-12-01 00:00:00
abstract::Radon ((222)Rn) measurements were undertaken in 16 samples of well water representing different depths and different types of aquifers found at the city centre of Konya, Central Turkey. The radon activity concentrations of the well water samples collected in the spring and summer seasons of 2012 were measured by using...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/nct099
更新日期:2013-10-01 00:00:00
abstract::Following a radiological or nuclear emergency, first responders and the public may become internally contaminated with radioactive materials, as demonstrated during the Goiânia, Chernobyl and Fukushima accidents. Timely monitoring of the affected populations for potential internal contamination, assessment of radiatio...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncw199
更新日期:2016-09-01 00:00:00
abstract::Activity concentrations of dissolved (222)Rn and (226)Ra were measured in several underground aquifers, which are candidates for repositories or for the study of analogue natural escapes of CO2. The concentration of both radionuclides in water was determined using liquid scintillation counting. The values obtained for...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncv232
更新日期:2015-11-01 00:00:00
abstract::Radiation protection (RP) in the use of medical cyclotrons involves many aspects both in the routine use and for the decommissioning of a site. Guidelines for site planning and installation, as well as for RP assessment, are given in international documents; however, the latter typically offer analytic methods of calc...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncw302
更新日期:2017-04-01 00:00:00
abstract::A module for proton track structure simulation in liquid water was implemented in the biophysical model PARTRAC. Simulated tracks of energy deposition events from the radiation under investigation were superimposed on a higher-order DNA target model describing the whole genome inside a human cell. The parameters contr...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/oxfordjournals.rpd.a006848
更新日期:2002-01-01 00:00:00
abstract::In an effort to understand the basic mechanism of the action of charged particles in solid radiation dosimeters, we extend our Monte-Carlo code (MC4) to condensed media (liquids/solids) and present new track-structure calculations for electrons and protons. Modeling the energy dissipation process is based on a model d...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/nci671
更新日期:2006-01-01 00:00:00
abstract::A Japanese adult male voxel (volume pixel) phantom (hereinafter referred to as the JM phantom) was constructed on the basis of CT images of a healthy Japanese adult male volunteer. Body characteristics of the JM phantom were compared with those of a voxelised MIRD5 type phantom and a Japanese adult male voxel phantom ...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncl101
更新日期:2007-01-01 00:00:00
abstract::Evaluation of LiF:Mg,Ti thermoluminescence dosemeters (TLDs) according to the high-temperature ratio (HTR) method enables the determination of the dose-average linear energy transfer (LET), the mean quality factor and the dose equivalent in mixed radiation fields of unknown composition. The neutron contribution is ass...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/nch209
更新日期:2004-01-01 00:00:00
abstract::From August 2016 to June 2017, the Public Health England-Centre for Radiation Chemical and Environmental Hazards (PHE-CRCE), collaborating centre of the WHO, through its Radiation Hazards and Emergencies Department Emergency Response Group has successfully supported five WHO Joint External Evaluation (JEE) missions in...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncy142
更新日期:2018-12-01 00:00:00
abstract::The frequencies and effective doses for the most common X-ray diagnostic examinations in Ukraine were assessed in the frame of the European Commission (EC) Study on European Population Doses from Medical Exposure (Dose Datamed 2). The average effective doses for all radiographic procedures were estimated using the ODS...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncv121
更新日期:2015-07-01 00:00:00
abstract::A multipurpose anthropomorphic neck phantom was designed and fabricated for use in medical applications. The designed neck phantom is composed of seven elliptic cylindrical slices with a semi-major axis of 14 cm and a semi-minor axis of 12.5 cm, each having the thickness of 2 cm. The thyroid gland, bony part of the ne...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncv359
更新日期:2016-03-01 00:00:00
abstract::In the framework of collaboration among the ENEA Radiation Protection Institute (Bologna), the ENEA Fusion Department (Frascati) and the INFN-LNF-Radiation Protection Group (Frascati), an experimental campaign was organised on the usage of thermoluminescence dosemeters (TLDs) for the dosimetric and spectrometric chara...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/nci577
更新日期:2006-01-01 00:00:00
abstract::A newly developed thermoluminescence dosemeter system is presented that is suitable for application in fields where personal monitoring of a large number of users is required. The system presented here is intended to be used as the upcoming main dosemeter for whole body dosimetry at the dosimetry service of the MPA NR...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncv478
更新日期:2016-09-01 00:00:00
abstract::The model and development is described of a new generation of Monte Carlo track structure codes. The code LEPHIST simulates full slowing down of low-energy proton history tracks in the range 1 keV-1 MeV and the code LEAHIST simulates low-energy alpha particle history tracks in the range 1 keV-8 MeV in water. All prima...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/oxfordjournals.rpd.a006838
更新日期:2002-01-01 00:00:00
abstract::Deposition of tritiated water vapour in the atmosphere to a water surface was studied in an outdoor field, where elevated concentrations of tritiated water vapour existed in the atmosphere over twelve days. Exchange velocities of tritiated water vapour between air and water were evaluated from tritium concentrations i...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/oxfordjournals.rpd.a006425
更新日期:2001-01-01 00:00:00
abstract::The US has far-reaching and extensive experience in the long-term management of areas contaminated with radioactive materials. This experience base includes the Department of Energy's continued follow-up with Hiroshima and Nagasaki from the 1940s at the Radiological Effects Research Foundation in Hiroshima, Japan, the...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章,评审
doi:10.1093/rpd/nch255
更新日期:2004-01-01 00:00:00
abstract::Optically stimulated luminescence (OSL) 'dot' dosemeters (manufactured by Landauer®) are reported to have a high degree of environmental stability, high level of sensitivity and provide wide range of dose measuring capabilities from 0.05 mGy to 100 Gy. The optical read out method is fast and relatively simple and perm...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncq289
更新日期:2011-01-01 00:00:00
abstract::Based on the non-intersection model of cylindrical capillaries, the mean radius of the pores of some soils and building materials are estimated. In size, the above-mentioned radii are usually of the order of the free path of gas molecules at atmospheric pressure. A review of pore size distribution data also reveals th...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/oxfordjournals.rpd.a006360
更新日期:2003-01-01 00:00:00
abstract::Since December 2006, approximately 3800 clinical chest tomosynthesis examinations have been performed at our department at Sahlgrenska University Hospital. A subset of the examinations has been included in studies of the detectability of pulmonary nodules, using computed tomography (CT) as the gold standard. Visibilit...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncq059
更新日期:2010-04-01 00:00:00
abstract::Estimation of the surface dose is very important for patients undergoing radiation therapy. The purpose of this study is to investigate the dose at the surface of a water phantom at a depth of 0.007 cm as recommended by the International Commission on Radiological Protection and International Commission on Radiation U...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/nct315
更新日期:2014-12-01 00:00:00
abstract::(238)U, (232)Th, (222)Rn and (220)Rn concentrations were measured inside various Moroccan black soap samples widely used by the Moroccan population in traditional baths (Hammans) by using both CR-39 and LR-115 type II solid state nuclear track detectors. The measured (238)U, (232)Th, (222)Rn and (220)Rn concentrations...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncq275
更新日期:2010-12-01 00:00:00
abstract::Radon exposure in schools is different from that in dwellings because the residence pattern is very different each other. So, when effective dose is calculated in schools, different approach should be considered from in dwellings. The aim of this study was to estimate actual effective dose due to inhaled radon conside...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncx216
更新日期:2018-04-01 00:00:00
abstract::A follow-up study was taken up in a mineralised zone situated in Hamirpur district, Himachal Pradesh, India, to investigate high values of radon concentrations reported in past studies as well to update the old radon data based on bare SSNTD technique. In the present investigation, the concentrations of indoor radon, ...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncv367
更新日期:2016-03-01 00:00:00
abstract::Experimental data on DNA double strand break (DSB) induction in human fibroblasts (AG1522), following irradiation with several radiation qualities, namely gamma rays, 0.84 MeV protons, 58.9 MeV u(-1) carbon ions, iron ions of 115 MeV u(-1), 414 MeV u(-1), 1 GeV u(-1), and 5 GeV u(-1), are presented. DSB yields were me...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncl389
更新日期:2006-01-01 00:00:00
abstract::AVIDOS is a computer code used for the dose assessment of aircraft crew exposed to cosmic radiation. The code employs a multiparameter model built upon simulations of cosmic radiation exposure done using the FLUKA Monte Carlo code. AVIDOS calculates both ambient dose equivalent H*(10) and effective dose E for flight r...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncp126
更新日期:2009-10-01 00:00:00