Abstract:
:Methodological problems arise on the way of radiation carcinogenesis modelling with the incorporation of radiobiological and cancer biology mechanistic data. The results of biophysical modelling of different endpoints [DNA DSB induction, repair, chromosome aberrations (CA) and cell proliferation] are presented and applied to the analysis of RBE-LET relationships for radiation-induced neoplastic transformation (RINT) of C3H/10T1/2 cells in culture. Predicted values for some endpoints correlate well with the data. It is concluded that slowly repaired DSB clusters, as well as some kind of CA, may be initiating events for RINT. As an alternative interpretation, it is possible that DNA damage can induce RINT indirectly via epigenetic process. A hypothetical epigenetic pathway for RINT is discussed.
journal_name
Radiat Prot Dosimetryjournal_title
Radiation protection dosimetryauthors
Andreev SG,Eidelman YA,Salnikov IV,Khvostunov IKdoi
10.1093/rpd/ncl463subject
Has Abstractpub_date
2006-01-01 00:00:00pages
335-9issue
1-4eissn
0144-8420issn
1742-3406pii
ncl463journal_volume
122pub_type
杂志文章abstract::During medical X-ray examinations of patients, humans as well as animals, voluntarily assisting persons are frequently needed in order to calm down the patient or animal. Typical exposure situations have been identified and measurements were performed in the fields of scattered X-rays. The personal dose equivalent H(p...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncq351
更新日期:2011-03-01 00:00:00
abstract::Radon gas concentrations in eight basements, four living rooms and four caves from different locations in Kabul and Panjsher, Afghanistan, were measured by using eight active radon exposure meters recently developed by the Helmholtz Center in Munich, Germany. The two-phase measurements lasted from a week to a year. In...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncx086
更新日期:2018-01-01 00:00:00
abstract::Dose response effects of diodes due to the high atomic number of silicon relative to water are investigated. While quality chances in the primary component of a megavoltage beam with depth are minimal. Compton scattered photons are shown to have a substantial effect on the quality leading to their enhanced absorption ...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/oxfordjournals.rpd.a006014
更新日期:2002-01-01 00:00:00
abstract::Craniospinal irradiation (CSI) is the standard treatment of primary intracranial tumour with risk of leptomeningeal dissemination. However, supine setup field-in-field technique does not need inter-fractional junction shift. Recently, the studies of CSI with tomotherapy showed excellent target coverage and tolerable n...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncr190
更新日期:2011-07-01 00:00:00
abstract::Crystalline rocks can produce dangerous radiation levels on the basis of their content in radioisotopes. Here, we report radiological data from 10 metamorphic and igneous rock samples collected from the crystalline basement of the Peloritani Mountains (southern Italy). In order to evaluate the radiological properties ...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncaa178
更新日期:2020-11-18 00:00:00
abstract::Adequate dose management during computed tomography is important. In the present study, the dosimetric application software ImPACT was added to a functional calculator of the size-specific dose estimate and was part of the scan settings for the auto exposure control (AEC) technique. This study aimed to assess the prac...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncw241
更新日期:2017-05-01 00:00:00
abstract::Radioactive liquid wastes of low-medium activity level are generated in radio immune assay (RIA) laboratories, which are also potentially infectious because of the pathogens from patient blood. The most common way of managing these wastes consists of a temporal storage, for partial radioactivity decay, followed by man...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/nci076
更新日期:2005-01-01 00:00:00
abstract::An investigation of the simultaneous unfolding of data from neutron spectrometers using the UMG codes MAXED and GRAVEL has been performed. This approach involves combining the data from the spectrometers before unfolding, thereby performing a single combined unfolding of all the data to yield a final combined spectrum...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncm082
更新日期:2007-01-01 00:00:00
abstract::An intercomparison exercise (IC) on whole body dosemeters to determine the quantity personal dose equivalent Hp (10) in photon radiation fields was jointly organised and conducted by the International Atomic Energy Agency (IAEA) and the Australian Radiation Protection and Nuclear Safety Agency (ARPANSA) for individual...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncz182
更新日期:2019-12-31 00:00:00
abstract::Thermoluminescene (TL) and mechanoluminescence (ML) properties of gamma-irradiated Dy activated potassium and magnesium mixed sulphate have been studied. (K2Mg2:Dy) (SO4)3 samples having different concentrations of Dy were prepared by solid-state diffusion method. Two distinct peaks, the first approximately 130 degree...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/nci607
更新日期:2006-01-01 00:00:00
abstract::In this study a set of structures has been simulated to represent a range of clinically relevant breast cancer mammographic lesions including solid tumours and microcalcifications. All structures have been created using simple random-based mathematical functions and have been inserted into a subset of digital mammogra...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/nch552
更新日期:2005-01-01 00:00:00
abstract::The three general principles of the International Commission on Radiological Protection (ICRP) are: justification, optimisation (ALARA) and dose limitation. The principle application of optimisation (ALARA) for occupational exposures of workers or the public to external radiation is reliant on low doses being assessed...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/nch094
更新日期:2004-01-01 00:00:00
abstract::In IR procedures, in order to evaluate the effective dose, the importance of the double dosemeter has been recognised, one worn above and one under the apron. Over the last few decades several algorithms have been developed to combine the readings of the dosemeters, however currently there is no international consensu...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncz136
更新日期:2019-12-31 00:00:00
abstract::Concentrations of beryllium-7 ((7)Be), lead-210 ((210)Pb) and caesium-137 ((137)Cs) were measured at two sites in the city of Belgrade (Serbia). One monitoring site was located in the central city area with heavy traffic and the other within the Institute of Nuclear Sciences Vinca, in the suburbs. Presented data cover...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncq211
更新日期:2010-12-01 00:00:00
abstract::From August 2016 to June 2017, the Public Health England-Centre for Radiation Chemical and Environmental Hazards (PHE-CRCE), collaborating centre of the WHO, through its Radiation Hazards and Emergencies Department Emergency Response Group has successfully supported five WHO Joint External Evaluation (JEE) missions in...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncy142
更新日期:2018-12-01 00:00:00
abstract::The connection between recorded volumetric CT dose index (CTDI vol) and determined mean fetal dose (Df) was examined from metal-oxide-semiconductor field-effect transistor dose measurements on an anthropomorphic female phantom in four stages of pregnancy in a 64-slice CT scanner. Automated tube current modulation kept...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncv097
更新日期:2015-07-01 00:00:00
abstract::The new RAMARN system for radon volume activity measurement was developed in 2003 and has been in use since then. RAMARN system consists of a plastic chamber that is conically cylindrical in shape and about 0.5 l in volume; a bare Kodak LR 115 is located on the bottom of this diffusion chamber. The size was chosen to ...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncn118
更新日期:2008-01-01 00:00:00
abstract::Hydrogen-filled proportional counters perform well as neutron spectrometers in the energy region from a few tens of keV up to ∼1.5 MeV. Unfortunately, gamma rays also generate signals in these detectors. It is possible in principle to distinguish the two types of event via the rise time of their respective signal puls...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/nct262
更新日期:2014-10-01 00:00:00
abstract::Costs related to the decommissioning of nuclear power plants create a significant financial burden for nuclear power plant operators. This article discusses the various methodologies employed by selected European countries for financing of the liabilities related to the nuclear power plant decommissioning. The article...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncv333
更新日期:2015-06-01 00:00:00
abstract::Radiation exposure during childhood is estimated to have a lifetime risk up to seven times greater than exposures at adult age. Therefore, paediatric patient dose monitoring is a major concern in radiology. The aim of this study is to evaluate the validity of a dose index, displayed at the digital imaging and communic...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncr313
更新日期:2012-05-01 00:00:00
abstract::Radon exposure in schools is different from that in dwellings because the residence pattern is very different each other. So, when effective dose is calculated in schools, different approach should be considered from in dwellings. The aim of this study was to estimate actual effective dose due to inhaled radon conside...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncx216
更新日期:2018-04-01 00:00:00
abstract::This paper describes the design and construction of a new performance testing programme that was implemented in Canada in 2008. The Canadian Regulator (Canadian Nuclear Safety Commission) had determined that their licensees, in addition to participating in the existing in vivo and in vitro performance tests, needed to...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncp088
更新日期:2009-06-01 00:00:00
abstract::Soil 222Rn concentration, CO2 and CH4 flux measurements were conducted around the Jwalamukhi area of North-West Himalayas, India. During this study, around 37 soil gas points and flux measurements were taken with the aim to assure the suitability of this method in the study of fault zones. For this purpose, RAD 7 (Dur...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncw071
更新日期:2016-10-01 00:00:00
abstract::In this work, the electromagnetic interference on hearing aids was evaluated. Electromagnetic (EM) immunity tests on different types of hearing aids were carried out, using signals of intensity and modulation comparable to those present in the environment. The purpose of this work is to characterise the interference, ...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/nch052
更新日期:2004-01-01 00:00:00
abstract::The results of measurements, which were performed at angiography departments, are presented. The aim of this work was not only to assess patient exposure but also to perform a survey of the occupational exposures of physicians during common angiography examinations of the skull, chest, abdomen and limbs. Patient data,...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/oxfordjournals.rpd.a006456
更新日期:2001-01-01 00:00:00
abstract::There is a preoccupation with linearity and absorbed dose as the basic quantifiers of radiation hazard. An alternative is the fluence approach, whereby radiation hazard may be evaluated, at least in principle, via an appropriate action cross section. In order to compare these approaches, it may be useful to discuss th...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/oxfordjournals.rpd.a006828
更新日期:2002-01-01 00:00:00
abstract::For the purpose of radiation protection, the reference neutron field for calibration of neutron monitors was constructed using radioactive neutron sources-bare-(252)Cf, D(2)O-moderated (252)Cf and (241)Am-Be(alpha,n)-at Korea Research Institute of Standards and Science (KRISS). The well-specified neutron source with i...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncm034
更新日期:2007-01-01 00:00:00
abstract::The paper presents the first results of an investigation on optical absorption (OA), thermally and infrared stimulated luminescence (TL and IRSL) of the Pinacate plagioclase (labradorite). The OA spectra reveal two bands with maxima at 1.0 and 3.2 eV connected with absorption of the Fe3+ and Fe2+ and IR absorption at ...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/nci643
更新日期:2006-01-01 00:00:00
abstract::The novel DIS-1 dosemeter developed by RADOS is based on ionisation chambers with so-called Direct Ion Storage (DIS). The dosemeter can measure Hp(10) and Hp(0.07) of photon and Hp(0.07) of beta irradiation. The characteristics of the commercially available DIS-1 dosemeter were studied at the Paul Scherrer Institute, ...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/oxfordjournals.rpd.a005984
更新日期:2002-01-01 00:00:00
abstract::The Smith-Etherington extrathoracic (ET) clearance model has been developed to describe clearance from the human nasal passage as observed for 1.5, 3 and 6 microm monodisperse particles inhaled by participants while sitting or at light exercise. Model parameter values have been determined for 22 sets of nasal clearanc...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/oxfordjournals.rpd.a006205
更新日期:2003-01-01 00:00:00