Radiation Protection Studies for Medical Particle Accelerators using Fluka Monte Carlo Code.

Abstract:

:Radiation protection (RP) in the use of medical cyclotrons involves many aspects both in the routine use and for the decommissioning of a site. Guidelines for site planning and installation, as well as for RP assessment, are given in international documents; however, the latter typically offer analytic methods of calculation of shielding and materials activation, in approximate or idealised geometry set-ups. The availability of Monte Carlo (MC) codes with accurate up-to-date libraries for transport and interaction of neutrons and charged particles at energies below 250 MeV, together with the continuously increasing power of modern computers, makes the systematic use of simulations with realistic geometries possible, yielding equipment and site-specific evaluation of the source terms, shielding requirements and all quantities relevant to RP at the same time. In this work, the well-known FLUKA MC code was used to simulate different aspects of RP in the use of biomedical accelerators, particularly for the production of medical radioisotopes. In the context of the Young Professionals Award, held at the IRPA 14 conference, only a part of the complete work is presented. In particular, the simulation of the GE PETtrace cyclotron (16.5 MeV) installed at S. Orsola-Malpighi University Hospital evaluated the effective dose distribution around the equipment; the effective number of neutrons produced per incident proton and their spectral distribution; the activation of the structure of the cyclotron and the vault walls; the activation of the ambient air, in particular the production of 41Ar. The simulations were validated, in terms of physical and transport parameters to be used at the energy range of interest, through an extensive measurement campaign of the neutron environmental dose equivalent using a rem-counter and TLD dosemeters. The validated model was then used in the design and the licensing request of a new Positron Emission Tomography facility.

journal_name

Radiat Prot Dosimetry

authors

Infantino A,Cicoria G,Lucconi G,Pancaldi D,Vichi S,Zagni F,Mostacci D,Marengo M

doi

10.1093/rpd/ncw302

subject

Has Abstract

pub_date

2017-04-01 00:00:00

pages

185-191

issue

1-3

eissn

0144-8420

issn

1742-3406

pii

ncw302

journal_volume

173

pub_type

杂志文章
  • VISUALIZATION OF THE DNA REPAIR PROCESS IN MAMMALIAN CELLS TRANSFECTED WITH EGFP-EXPRESSING PLASMID DNA AFTER EXPOSURE TO X-RAYS IN VITRO.

    abstract::To investigate the repair process of DNA damage induced by ionizing radiation in isolation from various types of cytoplasmic damage, we transfected X-irradiated enhanced green fluorescent protein (EGFP)-expressing plasmid DNA into non-irradiated mammalian cells using lipofectamine. The repair kinetics of the irradiate...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章

    doi:10.1093/rpd/ncy241

    authors: Nakaue H,Obata Y,Kaminaga K,Akimitsu N,Yokoya A

    更新日期:2019-05-01 00:00:00

  • Review of the correlation between results of cytogenetic dosimetry from blood lymphocytes and EPR dosimetry from tooth enamel for victims of radiation accidents.

    abstract::The goal of this study was to compare dose estimates from electron paramagnetic resonance (EPR) dosimetry with teeth and cytogenetic dosimetry with blood lymphocytes for 30 victims of radiation accidents. The whole-body exposures estimated by tooth enamel EPR dosimetry were ranging from 0.01 to 9.3 Gy. Study group com...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章

    doi:10.1093/rpd/ncu203

    authors: Khvostunov IK,Ivannikov AI,Skvortsov VG,Nugis VY,Golub EV

    更新日期:2015-03-01 00:00:00

  • Assessment of occupational exposure to uranium by indirect methods needs information on natural background variations.

    abstract::Urine monitoring is the preferred method to determine exposure to soluble compounds of uranium in workplaces. The interpretation of uranium contents in workers bioassay samples requires knowledge on uranium excretion and its dependence on intake by diet. Exceptionally high concentrations of natural uranium in private ...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章

    doi:10.1093/rpd/ncm155

    authors: Muikku M,Heikkinen T,Puhakainen M,Rahola T,Salonen L

    更新日期:2007-01-01 00:00:00

  • Development of a nanotechnology based low-LET multi-microbeam array single cell irradiation system.

    abstract::A novel single cell irradiation system using carbon nanotube (CNT) based field emission technology is proposed. The system can produce electron microbeam at a large range of pulsation frequencies and dose rates with energy between 20 and 60 keV. Different from any existing single beam microbeam device, the CNT-based s...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章

    doi:10.1093/rpd/ncl508

    authors: Chang S,Zhang J,Bordelon D,Schreiber E,Cox A,Zhou O

    更新日期:2006-01-01 00:00:00

  • General guidelines for the assessment of internal dose from monitoring data: progress of the IDEAS project.

    abstract::In recent major international intercomparison exercises on intake and internal dose assessments from monitoring data, the results calculated by different participants varied significantly. Based on this experience the need for harmonisation of the procedures has been formulated within an EU 5th Framework Programme res...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章

    doi:10.1093/rpd/ncl132

    authors: Doerfel H,Andrasi A,Bailey M,Blanchardon E,Cruz-Suarez R,Berkovski V,Castellani CM,Hurtgen C,LeGuen B,Malatova I,Marsh J,Stather J,Zeger J

    更新日期:2007-01-01 00:00:00

  • A comparative study of dielectric response function models for liquid water.

    abstract::Various methodologies that aim at an analytic representation of the dielectric response function (DRF) of liquid water with emphasis on the Bethe ridge region are compared. The use of optical data is a common feature to all models presented providing an empirical ground for modelling the valence energy losses where ma...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章

    doi:10.1093/rpd/ncl414

    authors: Emfietzoglou D,Nikjoo H,Pathak A

    更新日期:2006-01-01 00:00:00

  • FLEXIBLE, WIRELESS, INDUCTIVELY COUPLED SURFACE COIL RESONATOR FOR EPR TOOTH DOSIMETRY.

    abstract::Managing radiation injuries following a catastrophic event where large numbers of people may have been exposed to life-threatening doses of ionizing radiation relies on the availability of biodosimetry to assess whether individuals need to be triaged for care. Electron Paramagnetic Resonance (EPR) tooth dosimetry is a...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章

    doi:10.1093/rpd/ncw153

    authors: Schreiber W,Petryakov SV,Kmiec MM,Feldman MA,Meaney PM,Wood VA,Boyle HK,Flood AB,Williams BB,Swartz HM

    更新日期:2016-12-01 00:00:00

  • Investigation of combined unfolding of neutron spectra using the UMG unfolding codes.

    abstract::An investigation of the simultaneous unfolding of data from neutron spectrometers using the UMG codes MAXED and GRAVEL has been performed. This approach involves combining the data from the spectrometers before unfolding, thereby performing a single combined unfolding of all the data to yield a final combined spectrum...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章

    doi:10.1093/rpd/ncm082

    authors: Roberts NJ

    更新日期:2007-01-01 00:00:00

  • TWO NEW SINGLE-EXPOSURE, MULTI-DETECTOR NEUTRON SPECTROMETERS FOR RADIATION PROTECTION APPLICATIONS IN WORKPLACE MONITORING.

    abstract::This communication describes two new instruments, based on multiple active thermal neutron detectors arranged within a single moderator, that permit to unfold the neutron spectrum (from thermal to hundreds of MeV) and to determine the corresponding integral quantities with only one exposure. This makes them especially...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章

    doi:10.1093/rpd/ncw349

    authors: Gómez-Ros JM,Bedogni R,Bortot D,Domingo C,Esposito A,Introini MV,Lorenzoli M,Mazzitelli G,Moraleda M,Pola A,Sacco D

    更新日期:2017-04-01 00:00:00

  • Recent results of irradiations of DIS-1 dosemeters with an XR200 X-ray flash unit.

    abstract::Earlier measurements have revealed that active electronic dosemeters have deficiencies in pulsed fields of ionising radiation due to the counting technique used. The DIS-1 dosemeter uses a promising technology, which should be basically suitable for measurements in pulsed fields. In this paper, first measurements with...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章

    doi:10.1093/rpd/ncs265

    authors: Zutz H,Hupe O

    更新日期:2013-05-01 00:00:00

  • Blood tritium level as an estimate of soft tissue dose.

    abstract::To test the blood tritium level as an estimate of free water tritium (FWT) and organically bound tritium (OBT) in human soft tissues, a tritiated amino acid mixture (TAA) and tritiated water (HTO) were injected or orally administered to mice. Relatively high tritium retention in the blood was found after TAA injection...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.rpd.a006272

    authors: Saito M

    更新日期:2003-01-01 00:00:00

  • Early faecal excretion of inhaled plutonium.

    abstract::Special individual monitoring has been performed for suspected cases of inhalation of plutonium at the Tokai Works of the Japan Nuclear Cycle Development Institute (JNC). Some experimental data obtained from this special individual monitoring during the past 20 years are presented and discussed in this paper. Our expe...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.rpd.a006082

    authors: Kurihara O,Momose T,Tasaki T,Hayashi N,Shinohara K

    更新日期:2002-01-01 00:00:00

  • The TRADE experiment: shielding calculations for the building hosting the subcritical system.

    abstract::The TRADE project (TRiga Accelerator Driven Experiment), to be performed at the existing TRIGA reactor at ENEA Casaccia, has been proposed as a validation of the accelerator-driven system (ADS) concept. TRADE will be the first experiment in which the three main components of an ADS--the accelerator, spallation target ...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章

    doi:10.1093/rpd/nci219

    authors: Burn KW,Carta M,Casalini L,Kadi Y,Monti S,Nava E,Palomba M,Petrovich C,Picardi L,Rubbia C,Troiani F

    更新日期:2005-01-01 00:00:00

  • Radiation-induced DNA damage responses.

    abstract::The amazing feature of ionising radiation (IR) as a DNA damaging agent is the range of lesions it induces. Such lesions include base damage, single strand breaks (SSBs), double strand breaks (DSBs) of varying complexity and DNA cross links. A range of DNA damage response mechanisms operate to help maintain genomic sta...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章,评审

    doi:10.1093/rpd/ncl495

    authors: Jeggo P,Löbrich M

    更新日期:2006-01-01 00:00:00

  • Measurement of natural radioactivity in building materials used in Urumqi, China.

    abstract::Building materials contain natural radionuclides (226)Ra, (232)Th and (40)K, which cause direct radiation exposure of the public. The concentrations of (226)Ra, (232)Th and (40)K in commonly used building materials of Urumqi, China have been analysed using gamma-ray spectrometry. The concentrations of (226)Ra, (40)K a...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章

    doi:10.1093/rpd/nct002

    authors: Ding X,Lu X,Zhao C,Yang G,Li N

    更新日期:2013-07-01 00:00:00

  • VALIDATION OF A BEAMNRC MONTE CARLO SIMULATION OF A BROAD BEAM DIAGNOSTIC X-RAY UNIT.

    abstract::A BEAMnrc Monte Carlo simulation of a diagnostic X-ray unit in a broad beam geometry intended for the derivation of effective linear attenuation coefficients was validated against measurements made on the X-ray unit on which the simulation was based. The validation process assessed the size of the beam, the first and ...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章

    doi:10.1093/rpd/ncz032

    authors: Worrall M,Sutton DG

    更新日期:2019-12-31 00:00:00

  • Activity concentrations and mean annual effective dose from gamma-emitting radionuclides in the Lebanese diet.

    abstract::Since the primary factor contributing to the internal effective dose in the human organism is contaminated food, the control of radionuclides in food represents the most important means of protection. This study was conducted to determine the levels of the dietary exposure of the Lebanese population to gamma-emitting ...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章

    doi:10.1093/rpd/ncn160

    authors: Nasreddine L,El Samad O,Hwalla N,Baydoun R,Hamzé M,Parent-Massin D

    更新日期:2008-01-01 00:00:00

  • Methodology for Simple Spot Measurement of Equilibrium Equivalent Radon Concentration.

    abstract::Estimation of the effective inhalation dose of short half-life radon progeny requires the quantification of radon equilibrium equivalent activity concentrations (EEC, Ceq). The aim of the present study is to develop new methodology that focuses on spot measurements to determine EEC from single gross alpha counts and d...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章

    doi:10.1093/rpd/ncaa176

    authors: Sakoda A,Ishimori Y,Kanzaki N,Tanaka H

    更新日期:2020-11-13 00:00:00

  • Determination of radon concentration levels in well water in Konya, Turkey.

    abstract::Radon ((222)Rn) measurements were undertaken in 16 samples of well water representing different depths and different types of aquifers found at the city centre of Konya, Central Turkey. The radon activity concentrations of the well water samples collected in the spring and summer seasons of 2012 were measured by using...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章

    doi:10.1093/rpd/nct099

    authors: Erdogan M,Eren N,Demirel S,Zedef V

    更新日期:2013-10-01 00:00:00

  • Dose assessment from activated sodium within a body in criticality accidents.

    abstract::Some data were derived using recent sophisticated methods to rapidly convert specific activity of induced 24Na to average dose over a whole body in criticality accidents. Monte Carlo calculations using the MCNP-4B code were performed to study energy spectra of neutrons and gamma rays for some criticality systems with ...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.rpd.a006350

    authors: Takahashi F,Endo A,Yamaguchi Y

    更新日期:2003-01-01 00:00:00

  • Characterisation of non-constant background in counting measurements.

    abstract::A 'moving-target' method for characterising background in a counting measurement in which the instantaneous background count rate is a function of time, rather than being fixed, is proposed. This model treats the average Poisson mean in observation period P as coming from a gamma distribution with parameters αP and βP...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章

    doi:10.1093/rpd/ncu297

    authors: Klumpp J,Miller G,Brandl A

    更新日期:2015-04-01 00:00:00

  • Indoor radon measurements in Turkey dwellings.

    abstract::In this work, indoor radon radioactivity concentration levels have been measured in dwellings of Turkey within the frame of the National Radon Monitoring Programme. The (222)Rn concentrations were measured with time-integrating passive nuclear etched track detectors in 7293 dwellings in 153 residential units of 81 pro...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章

    doi:10.1093/rpd/ncu329

    authors: Celebi N,Ataksor B,Taskın H,Bingoldag NA

    更新日期:2015-12-01 00:00:00

  • 226Ra, 222Rn AND PERMEABILITY OF BELGIAN SOILS IN RELATION WITH INDOOR RADON RISK.

    abstract::Knowing the concentration of 226Ra in soil and of 222Rn in soil gas is important for the analysis of indoor radon data and the prediction of radon-prone areas. Except for soil Rn in Ardenne, the data concerning these two radionuclides in Belgian soils are very scarce. In the context of Master theses and international ...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章

    doi:10.1093/rpd/ncx163

    authors: Licour C,Tondeur F,Gerardy I,Alaoui NM,Dubois N,Perreaux R,Gerardy N,Christiaens D

    更新日期:2017-11-01 00:00:00

  • Monte Carlo calculations applied to the parametrical studies in a whole body counter.

    abstract::The use of a Monte Carlo code for the analysis and interpretation of whole body counting measurements is described. The sources of error are analysed and commented to show how a counting geometry can be improved by improving accuracy and precision in a measurement. The effects of body size, contamination distribution ...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章

    doi:10.1093/rpd/ncm242

    authors: Genicot JL,Koukouliou V,Carinou E

    更新日期:2008-01-01 00:00:00

  • Patient dose in neonatal units.

    abstract::Lung disease represents one of the most life-threatening conditions in prematurely born children. In the evaluation of the neonatal chest, the primary and most important diagnostic study is therefore the chest radiograph. Since prematurely born children are very sensitive to radiation, those radiographs may lead to a ...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章

    doi:10.1093/rpd/ncn237

    authors: Smans K,Struelens L,Smet M,Bosmans H,Vanhavere F

    更新日期:2008-01-01 00:00:00

  • Radon progeny in hydrometeors at the earth's surface.

    abstract::During atmospheric thermal inversions, dew and hoarfrost concentrate gamma emitting radionuclides of the short-lived (222)Rn progeny ((214)Pb and (214)Bi), causing an increase in the total natural gamma background from the ground. To highlight this phenomenon, a volcanic zone of high (222)Rn flux was studied during th...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章

    doi:10.1093/rpd/ncr402

    authors: Voltaggio M

    更新日期:2012-07-01 00:00:00

  • Performance of CVD diamond as an optically and thermally stimulated luminescence dosemeter.

    abstract::Diamond is a material with extreme physical properties. Its radiation hardness, chemical inertness and tissue equivalence qualify it as an ideal material for radiation dosimetry. In the present work, the optically stimulated luminescence (OSL) and thermoluminescence (TL) characteristics of a 10 microm thick CVD diamon...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章

    doi:10.1093/rpd/nci667

    authors: Preciado-Flores S,Schreck M,Meléndrez R,Chernov V,Bernal R,Cruz-Vázquez C,Cruz-Zaragoza E,Barboza-Flores M

    更新日期:2006-01-01 00:00:00

  • Monte Carlo calculations for efficiency calibration of a whole-body monitor using BOMAB phantoms of different sizes.

    abstract::Internal contamination due to high-energy photon (HEP) emitters is assessed using a scanning bed whole-body monitor housed in a steel room at the Bhabha Atomic Research Centre (BARC). The monitor consists of a (203 mm diameter × 102 mm thickness) NaI(Tl) detector and is calibrated using a Reference BOMAB phantom repre...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章

    doi:10.1093/rpd/ncr203

    authors: Bhati S,Patni HK,Ghare VP,Singh IS,Nadar MY

    更新日期:2012-03-01 00:00:00

  • Absorbed dose rate estimation for protons, leptons and helium observed with AMS01 experiment in low earth orbit during STS-91 mission.

    abstract::The Alpha Magnetic Spectrometer (AMS01), a high-sensitivity particle spectrometer, was successfully flown for 10 d in June 1998 (STS91) in the orbit of the International Space Station (51.7 degrees, -380 km). A high-statistics dataset of galactic cosmic rays were measured as a function of geomagnetic latitude, includi...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章

    doi:10.1093/rpd/nci071

    authors: Ionica M,Alpat B,Ambrosi G,Battiston R,Bertucci B,Burger WJ,Caraffini D,Cecchi C,Dinu N,Esposito G,Fiandrini E,Ionica R,Menichelli M,Pauluzzi M,Zuccon P

    更新日期:2005-01-01 00:00:00

  • Survey of patient dose in computed tomography in Syria 2009.

    abstract::The radiation doses to patient in computed tomography (CT) in Syria have been investigated and compared with similar studies in different countries. This work surveyed 30 CT scanners from six different manufacturers distributed all over Syria. Some of the results in this paper were part of a project launched by the In...

    journal_title:Radiation protection dosimetry

    pub_type: 杂志文章

    doi:10.1093/rpd/ncq155

    authors: Kharita MH,Khazzam S

    更新日期:2010-09-01 00:00:00