Recovery of vestibular function following hair cell destruction by streptomycin.

abstract：:Despite advances in technology, the ability to perceive music remains limited for many cochlear implant users. This paper reviews the technological, biological, and acoustical constraints that make music an especially challenging stimulus for cochlear implant users, while highlighting recent research efforts to overco...

journal_title：Hearing research

authors： Limb CJ,Roy AT

更新日期：2014-02-01 00:00:00

abstract：:In common inbred mouse strains, hearing loss is a highly prevalent quantitative trait, which is mainly controlled by the Cdh23(753A) variant and alleles at numerous other strain-specific loci. Here, we investigated the genetic basis of hearing loss in non-inbred strains. Mice of Swiss Webster, CF-1, NIH Swiss, ICR, an...

journal_title：Hearing research

authors： Drayton M,Noben-Trauth K

更新日期：2006-02-01 00:00:00

abstract：:Spongiform lesions of the gerbil cochlear nucleus are reduced in number and extent by rearing in acoustic isolation compared with rearing while exposed to normal colony low-frequency background noise. This study tested whether rearing under exposure to noise bands of moderate intensity would increase the number and ex...

journal_title：Hearing research

authors： McGinn MD,Faddis BT

更新日期：1994-12-01 00:00:00

abstract：:Endocochlear potentials (EPs) were investigated in healthy guinea pigs and in those exposed to white noise of 125 dB SPL for 20-80 min. EPs were measured during and after temporary anoxia (3.5 min, denoted as reversible anoxia) and then during continuous anoxia to evaluate noise-induced changes in EP properties. Succi...

journal_title：Hearing research

authors： Wang JA,Dong WJ,Chen JS

更新日期：1990-03-01 00:00:00

abstract：:Sustained vocalizations of vowels [a], [i], and syllable [mə] were collected in twenty normal-hearing individuals. On vocalizations, five conditions of different audio-vocal feedback were introduced separately to the speakers including no masking, wearing supra-aural headphones only, speech-noise masking, high-pass no...

journal_title：Hearing research

authors： Lee SH,Hsiao TY,Lee GS

更新日期：2015-06-01 00:00:00

abstract：:Estrogen signaling in auditory and vestibular sensory epithelia is a newly emerging focus propelled by the role of estrogen signaling in many other proliferative systems. Understanding the pathways with which estrogen interacts can provide a means to identify how estrogen may modulate proliferative signaling in inner ...

journal_title：Hearing research

authors： McCullar JS,Oesterle EC

更新日期：2009-06-01 00:00:00

abstract：:Using morphological criteria, death pathways in outer hair cells (OHCs) were determined in chinchilla organs of Corti that had been exposed to a high- or moderate-level octave band of noise (OBN) centered at either 0.5 or 4-kHz. The specimens were part of our large collection of plastic-embedded flat preparations of c...

journal_title：Hearing research

authors： Bohne BA,Harding GW,Lee SC

更新日期：2007-01-01 00:00:00

abstract：:Left ear noise-induced hearing losses are dominant in the army. The common explanation is the asymmetrical effect of the shooting posture. However, firm evidence to support this possibility is still lacking. In the French army shooters, eye preference rather than hand preference for shooting determines the side of sho...

journal_title：Hearing research

authors： Job A,Grateau P,Picard J

更新日期：1998-08-01 00:00:00

abstract：:Most previous reports of ototoxicity following exposure to several volatile organic solvents have restricted testing to the low- and mid-frequencies (2-20 kHz) of the hearing range in the rat (0.25-80 kHz). We report here that inhalation exposure to styrene, mixed xylene, toluene, and 1,1,2-trichloroethylene resulted ...

journal_title：Hearing research

authors： Crofton KM,Lassiter TL,Rebert CS

更新日期：1994-10-01 00:00:00

abstract：:Voltage-dependent K+ channels in the basolateral membrane of hair cells in guinea-pig cochlea might contribute to the non-linear current-voltage relationships in these hair cells and, thereby, to generation of the extracellular summating potential (SP). To evaluate the role of K+ channels in the generation of the SP t...

journal_title：Hearing research

authors： van Emst MG,Klis SF,Smoorenburg GF

更新日期：1995-08-01 00:00:00

abstract：:Acetylcholine (ACh) is a neuromodulator that is likely to play a role in plasticity as well as other phenomena at many sites in the auditory system. The auditory cortex receives cholinergic innervation from the basal forebrain, whereas the cochlea receives cholinergic innervation from the superior olivary complex. Muc...

journal_title：Hearing research

authors： Schofield BR,Motts SD,Mellott JG

更新日期：2011-09-01 00:00:00

abstract：:A growing body of evidence implies that the dorsal cochlear nucleus (DCN) plays an important role in tinnitus. To test the hypothesis that the rostral output of the DCN is necessary for the experience of chronic tinnitus, the dorsal DCN and the dorsal acoustic stria of rats with psychophysical evidence of tinnitus was...

journal_title：Hearing research

authors： Brozoski TJ,Bauer CA

更新日期：2005-08-01 00:00:00

abstract：:The olivocochlear bundle was sectioned at the floor of the fourth ventricle in a series of cats. From three to thirty weeks post-operatively, recordings were made from single auditory-nerve fibers. Tuning curves, spontaneous discharge rates, and rate-level functions for tones at the characteristic frequency were measu...

journal_title：Hearing research

authors： Liberman MC

更新日期：1990-11-01 00:00:00

abstract：:1. The sound pressure level required to produce a detectable gross action potential (N1) in the guinea pig was measured for a range of frequencies. The resulting electrocochleogram was compared with the click level require to produce a detectable N1. 2. Over most of the auditory range (1-30 kHz) the required click lev...

journal_title：Hearing research

authors： Johnstone JR

更新日期：1981-07-01 00:00:00

abstract：:The avian auditory papilla provides an interesting object on which to study efferent influences, because whereas a significant population of hair cells in birds is not afferently innervated, all hair cells are efferently innervated (Fischer, 1992, 1994a, b). Previous studies in mammals using contralateral sound to sti...

journal_title：Hearing research

authors： Manley GA,Taschenberger G,Oeckinghaus H

更新日期：1999-12-01 00:00:00

abstract：:The radial width of three rows of cuticular plates of outer hair cells (width of the OHC triad), the distribution of inner hair cells along the organ of Corti, and postnatal maturation of the middle ear were examined in rats of the Srague-Dawley and Lewis strains aged 0-24 days and two months. The width of the OHC tri...

journal_title：Hearing research

authors： Burda H

更新日期：1985-03-01 00:00:00

abstract：:The relation between hearing loss and loss of hair cells after prolonged exposure to a simulated industrial noise environment was determined in normotensive albino rats. Hearing loss was assessed behaviorally by a conditioned suppression technique and electrophysiologically by auditory brainstem response to pulses of ...

journal_title：Hearing research

authors： Borg E

更新日期：1987-01-01 00:00:00

abstract：:It has been demonstrated that INS can be utilized to stimulate spiral ganglion cells in the cochlea. Although neural stimulation can be achieved without direct contact of the radiation source and the tissue, the presence of fluids or bone between the target structure and the radiation source may lead to absorption or ...

journal_title：Hearing research

authors： Moreno LE,Rajguru SM,Matic AI,Yerram N,Robinson AM,Hwang M,Stock S,Richter CP

更新日期：2011-12-01 00:00:00

abstract：:The distribution of actin, alpha-actinin, fimbrin, tropomyosin and tubulin in the apical region of inner and outer hair cells was studied by immunofluorescent localization of antibodies to these proteins. The macromolecular distribution of actin and alpha-actinin was studied using post-embedding immunoelectron microsc...

journal_title：Hearing research

authors： Slepecky N,Chamberlain SC

更新日期：1985-01-01 00:00:00

abstract：:Eye color may be an indicator of inner ear melanin content and has been associated with hearing loss. There is controversy as to whether eye color has an effect on acquired causes of sensorineural hearing loss. This review was conducted to analyze the literature evaluating the relationship between eye color and causes...

journal_title：Hearing research

authors： Mujica-Mota MA,Schermbrucker J,Daniel SJ

更新日期：2015-02-01 00:00:00

abstract：:Previous studies indicate the presence of adenosine receptors in the cochlear tissues obtained from different animals. This study was initiated to determine the subtypes of adenosine receptor (AR) present in the chinchilla cochlea and to assess their function. Radioligand binding studies demonstrate the presence of bo...

journal_title：Hearing research

authors： Ford MS,Maggirwar SB,Rybak LP,Whitworth C,Ramkumar V

更新日期：1997-03-01 00:00:00

abstract：:The influence of noise exposure on the endothelial transport system in the cochlea was investigated using cationic polyethyleneimine (PEI), since systemically administered PEI passes through the capillary endothelial cell and attaches to basal lamina (BL) anionic sites in the cochlea. Under general anesthesia, all gui...

journal_title：Hearing research

authors： Suzuki M,Yamasoba T,Ishibashi T,Miller JM,Kaga K

更新日期：2002-02-01 00:00:00

abstract：:Exposure to harsh environment induces stress reactions that increase probability of survival. Stress influences the endocrine, nervous and immune systems and affects the functioning of a variety of organs. Numerous researchers demonstrated that a 24-h exposure to an acoustic rodent repellent provokes stress reaction i...

journal_title：Hearing research

authors： Mazurek B,Haupt H,Joachim R,Klapp BF,Stöver T,Szczepek AJ

更新日期：2010-01-01 00:00:00

abstract：:Auditory evoked magnetic fields were measured using a stimulation sequence where repetitive identical tone bursts were randomly and infrequently replaced by shorter tones. The deviation in the stimulus duration evoked a specific response, the mismatch field, peaking about 130 ms after the end of the shorter stimulus. ...

journal_title：Hearing research

authors： Kaukoranta E,Sams M,Hari R,Hämäläinen M,Näätänen R

更新日期：1989-08-01 00:00:00

abstract：:Chromogranin A (CgA) belongs to the family of chromogranin peptides which are contained in large dense-core vesicles. The novel CgA fragment catestatin (bovine CgA(344-364); RSMRLSFRARGYGFRGPGLQL) is a potent inhibitor of catecholamine release by acting as a nicotinic cholinergic antagonist. Catestatin is a recently c...

journal_title：Hearing research

authors： Bitsche M,Mahata SK,Marksteiner J,Schrott-Fischer A

更新日期：2003-10-01 00:00:00

abstract：:Inner hair cells (IHCs) were isolated from the 3rd and 4th turn of the guinea-pig cochlea using a new microsurgical technique. Microelectrode impalements in vitro with conventional microelectrodes yielded intracellular potentials of -14 +/- 7 mV (mean +/- SD, N = 43) at 24 degrees C. This suggested depletion of intrac...

journal_title：Hearing research

authors： Gitter AH,Zenner HP

更新日期：1990-04-01 00:00:00

abstract：:The phase angle, alpha, between a tonal signal and a tonal masker was varied from 0 degrees to 135 degrees in simultaneous masking, forward masking, and pulsation-threshold paradigms. In all conditions the frequency of the signal and masker was 500 Hz. For forward masking both diotic (MOSO) and dichotic (MOS pi) liste...

journal_title：Hearing research

authors： Yost WA,Grantham DW,Lutfi RA,Stern RM

更新日期：1982-08-01 00:00:00

abstract：:Owing to the advances in transgenic animal technology and the advent of the next-generation sequencing era, over 120 genes causing hereditary hearing loss have been identified by now. In parallel, the field of human gene therapy continues to make exciting and rapid progress, culminating in the recent approval of sever...

journal_title：Hearing research

authors： Fakhiri J,Landegger LD,Grimm D

更新日期：2020-10-15 00:00:00

abstract：:Inhibition of sodium/potassium pumping by isolated goldfish hair cells led to a rapid gain of sodium and loss of potassium. Half-times for turnover were about 10 min, among the fastest of any cell type examined by electron-probe analysis. Pumping was inhibited by removal of extracellular potassium or by treatment with...

journal_title：Hearing research

authors： Mroz EA,Nissim KR,Lechene C

更新日期：1993-10-01 00:00:00

abstract：:Acetylcholine (ACh) is the dominant transmitter released from inner ear efferent neurons. In frog vestibular organs, these efferent neurons synapse exclusively with type II hair cells. Hair cells isolated from the frog saccule hyperpolarize following the application of 50 microM ACh, thereby demonstrating the presence...

journal_title：Hearing research

authors： Holt JC,Pantoja AM,Athas GB,Guth PS

更新日期：2000-08-01 00:00:00