Abstract:
:The European Commission has decided on harmonized classifications for a large number of individual chemicals according to its own directive for classification and labeling of dangerous substances. We have compared the harmonized classifications for acute oral toxicity to the acute oral toxicity data available in the RTECS database. Of the 992 substances eligible for this comparison, 15% were assigned a too low danger class and 8% a too high danger class according to the RTECS data. Due to insufficient transparency-scientific documentations of the classification decisions are not available-the causes of this discrepancy can only be hypothesized. We propose that the scientific motivations of future classifications be published and that the apparent over- and underclassifications in the present system be either explained or rectified, according to what are the facts in the matter.
journal_name
Toxicol Lettjournal_title
Toxicology lettersauthors
Rudén C,Hansson SOdoi
10.1016/s0378-4274(03)00204-2keywords:
subject
Has Abstractpub_date
2003-09-30 00:00:00pages
159-72issue
2eissn
0378-4274issn
1879-3169pii
S0378427403002042journal_volume
144pub_type
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journal_title:Toxicology letters
pub_type: 杂志文章
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