Abstract：
:Resistance and sensitivity to normal human serum (NHS) of Trypanosoma congolense, a parasite believed to cause disease in animals only, were investigated in vivo as well as in vitro. Our results indicate that like Trypanosoma brucei, T. congolense can be grouped into three different phenotypes according to its resistance to NHS. Some strains are completely resistant to NHS, like Trypanosoma brucei gambiense and the resistant form of Trypanosoma brucei rhodesiense. Other strains show a very low degree of resistance comparable to the sensitive form of T. b. rhodesiense, and some are completely sensitive to NHS. Continuous passaging in mice in the presence or absence of NHS shows that the resistance and sensitivity of T. congolense can be reversed like in T. b. rhodesiense. Our data suggest that T. congolense might be able to infect man in regions where animals may serve as reservoirs for the infection.
journal_name
Exp Parasitoljournal_title
Experimental parasitologyauthors
Xong HV,De Baetselier P,Pays E,Magez Sdoi
10.1016/s0014-4894(03)00032-8keywords:
subject
Has Abstractpub_date
2002-10-01 00:00:00pages
61-5issue
2eissn
0014-4894issn
1090-2449pii
S0014489403000328journal_volume
102pub_type
杂志文章abstract：:Members of a serologically cross-reacting family of proteins including Ag332 and Pf11.1, megadalton proteins of schizont-infected red blood cells, and gametocytes, respectively, and Pf155-RESA, a 155-kDa protein of ring-infected red blood cells, have been reported to share amino acid repeat sequences. These repeats ar...
journal_title：Experimental parasitology
pub_type： 杂志文章
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journal_title：Experimental parasitology
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journal_title：Experimental parasitology
pub_type： 杂志文章,评审
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journal_title：Experimental parasitology
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journal_title：Experimental parasitology
pub_type： 杂志文章
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journal_title：Experimental parasitology
pub_type： 杂志文章
doi：10.1016/j.exppara.2008.11.004
更新日期：2009-03-01 00:00:00
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pub_type： 杂志文章
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更新日期：2014-05-01 00:00:00
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pub_type： 杂志文章
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journal_title：Experimental parasitology
pub_type： 杂志文章
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更新日期：2011-11-01 00:00:00
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journal_title：Experimental parasitology
pub_type： 杂志文章
doi：10.1006/expr.1999.4413
更新日期：1999-07-01 00:00:00
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pub_type： 杂志文章
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更新日期：1986-08-01 00:00:00
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journal_title：Experimental parasitology
pub_type： 杂志文章
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更新日期：1999-10-01 00:00:00
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pub_type： 杂志文章
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更新日期：2009-10-01 00:00:00
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journal_title：Experimental parasitology
pub_type： 杂志文章
doi：10.1016/j.exppara.2017.09.009
更新日期：2017-12-01 00:00:00
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pub_type： 杂志文章
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更新日期：1991-07-01 00:00:00
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pub_type： 杂志文章
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pub_type： 杂志文章
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更新日期：2005-12-01 00:00:00
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pub_type： 杂志文章
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pub_type： 杂志文章
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更新日期：2012-04-01 00:00:00
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pub_type： 杂志文章
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pub_type： 杂志文章
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pub_type： 杂志文章
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更新日期：2013-01-01 00:00:00
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更新日期：2010-04-01 00:00:00
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journal_title：Experimental parasitology
pub_type： 杂志文章
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