Plasmodium falciparum: freeze-fracture of the gametocyte pellicular complex.

Abstract:

:Freeze-fracturing has been used to study the architecture of the pellicular complex of the gametocytes of Plasmodium falciparum. The gametocyte is surrounded by three membranes and a layer of subpellicular microtubules. During freeze-fracturing, each of the three membranes is split along its hydrophobic interior to yield a total of six fracture faces. The most obvious feature of each fracture face is the presence of globular intramembranous particles on their surfaces. The six fracture faces differ from one another in arrangement, size, and density of these intramembranous particles. In gametocytes, unlike in sporozoites, the intramembranous particles are always distributed randomly and lack any definite pattern or orientations. A unique feature of gametocytes revealed by the freeze-fracturing technique is the presence of several transverse sutures on the middle membrane that encircle the gametocyte and give it a segmented appearance.

journal_name

Exp Parasitol

authors

Meszoely CA,Erbe EF,Steere RL,Trosper J,Beaudoin RL

doi

10.1016/0014-4894(87)90040-3

subject

Has Abstract

pub_date

1987-12-01 00:00:00

pages

300-9

issue

3

eissn

0014-4894

issn

1090-2449

journal_volume

64

pub_type

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