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Study on the increment of the production of gastric mucus in rats treated with Opuntia ficus indica (L.) Mill. cladodes.

Abstract：

:Opuntia ficus indica cladodes are used in traditional medicine of many countries for their cicatrisant activity. The major components of cladodes are carbohydrate-containing polymers, which consist of a mixture of mucilage and pectin. In this paper we studied the cytoprotective effects of cladodes on experimental ethanol-induced ulcer in rat. The O. ficus indica cladodes administration gives rise to cytoprotection phenomena by breaking up the epithelial cells and stimulating an increase in mucus production. When O. ficus indica cladodes are administered as a preventive therapy, keep the gastric mucosa under normal condition by preventing mucus dissolution caused by ethanol and favouring mucus production. An increase of mucus production is also observed during the course of the curative treatment. The treatment with O. ficus indica cladodes provokes an increase in the number of secretory cells. Probably, the gastric fibroblasts are involved in the antiulcer activity.

journal_name

J Ethnopharmacol

journal_title

Journal of ethnopharmacology

authors

Galati EM,Pergolizzi S,Miceli N,Monforte MT,Tripodo MM

doi

10.1016/s0378-8741(02)00243-x

keywords:

subject

Has Abstract

pub_date

2002-12-01 00:00:00

pages

229-33

issue

3

eissn

0378-8741

issn

1872-7573

pii

S037887410200243X

journal_volume

83

pub_type

杂志文章

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