Abstract:
:The vasorelaxing activity of the aqueous extracts of Casimiroa edulis seeds F(AECe) on mesenteric arterial bed (MAB) of rats was studied. MAB precontracted with methoxamine was mounted on a tissue bath and exposed to plant extracts (bolus 50, 500, 2500 and 5000 microg). The bolus injections of AECe significantly inhibited, in a concentration-dependent manner, the maximal contractile response induced by methoxamine (30 microm) in MAB. After endothelium removal, the vascular ability of Casimiroa edulis aqueous extract was significantly changed. Treatment with an inhibitor of NO synthase (L-NOA, 10 microM) also modified the AECe effect. The guanilate cyclase inhibitor methylene blue (MB, 100 microM) inhibited the AECe-induced vasodilatation. These results suggest the involvement of NO of endothelial source (or related factors) in this vasodilator effect.
journal_name
J Ethnopharmacoljournal_title
Journal of ethnopharmacologyauthors
Baisch AL,Urban H,Ruiz ANdoi
10.1016/j.jep.2004.06.018keywords:
subject
Has Abstractpub_date
2004-12-01 00:00:00pages
163-7issue
2-3eissn
0378-8741issn
1872-7573pii
S0378-8741(04)00301-0journal_volume
95pub_type
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journal_title:Journal of ethnopharmacology
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abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Pogostemon cablin has been widely used in traditional Chinese medicine for the treatment of many diseases, including skin disorders. In the skin beauty and care prescriptions, Pogostemon cablin is one of the top ten frequently used traditional Chinese medicines. AIM OF THE STUDY:The pres...
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journal_title:Journal of ethnopharmacology
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journal_title:Journal of ethnopharmacology
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journal_title:Journal of ethnopharmacology
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更新日期:1998-07-01 00:00:00
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journal_title:Journal of ethnopharmacology
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更新日期:2008-08-13 00:00:00
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journal_title:Journal of ethnopharmacology
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journal_title:Journal of ethnopharmacology
pub_type: 历史文章,杂志文章
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更新日期:2016-08-02 00:00:00
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journal_title:Journal of ethnopharmacology
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journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
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更新日期:2006-11-24 00:00:00
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journal_title:Journal of ethnopharmacology
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abstract:ETHNOPHARMACOLOGICAL RELEVANCE:The lack of ethnoveterinary surveys in Brazil, especially in the Amazon region, results in losses in the veterinary phytopharmacology field and in scientific documentation of the cultural traditions of plant use in the treatment of animal diseases. AIM OF THE STUDY:To catalog, analyze an...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
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更新日期:2012-11-21 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:The modified-Chungsimyeolda-tang (DG) is an important traditional Korean herbal formula used in traditional oriental medicine for treatment of cerebrovascular disorders, including stroke. The formula is based on the book "Dongui Sasang Shinpyun". AIM OF THE STUDY:In the previous studies,...
journal_title:Journal of ethnopharmacology
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