Pharmacological screening of the anti-ulcerogenic effects of some Jordanian medicinal plants in rats.

Abstract:

:Ethanolic extracts of 18 medicinal plants traditionally used in Jordan for the treatment of gastric ulcers were evaluated for their possible anti-ulcer activity. Among the tested plants, 12 extracts lowered the severity of ethanol-induced gastric damage in rats with curative ratios ranging from 62.9 to 99.5%. The most active extract was that of Quercus coccifera, with a curative ratio of 99.5%.

journal_name

J Ethnopharmacol

authors

Alkofahi A,Atta AH

doi

10.1016/s0378-8741(98)00126-3

keywords:

subject

Has Abstract

pub_date

1999-11-30 00:00:00

pages

341-5

issue

3

eissn

0378-8741

issn

1872-7573

pii

S0378874198001263

journal_volume

67

pub_type

杂志文章
  • Antidiarrhoeal and intestinal modulatory activities of Wei-Chang-An-Wan extract.

    abstract:AIM OF THE STUDY:Wei-Chang-An-Wan (WCAW), a traditional pharmaceutical preparation, has been used for treating various gastrointestinal (GI) diseases for several decades, but it is still poorly understood how it works on those disorders. This study was to investigate the effects of WCAW extract on GI tract. MATERIALS ...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2009.07.027

    authors: Hu J,Gao WY,Ling NS,Liu CX

    更新日期:2009-09-25 00:00:00

  • Exploration of the hepatoprotective chemical base of an orally administered herbal formulation (YCHT) in normal and CCl4-intoxicated liver injury rats. Part 2: Hepatic disposition in vivo and hepatoprotective activity in vitro.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Yin-Chen-Hao Tang (YCHT) has been a very popular, hepatoprotective three-herb formula with an unclear chemical base. AIM OF THIS STUDY:To reveal the hepatoprotective chemical base of oral-dosed YCHT, we bridged the hepatic disposition of six compounds in vivo and their hepatoprotection i...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2019.02.022

    authors: Tian X,Liu H,Qiao S,Yin H,Chen M,Hu P,Wang Y,Peng H,Liu F,Pan G,Huang C

    更新日期:2019-05-23 00:00:00

  • The traditional drug Gongjin-Dan ameliorates chronic fatigue in a forced-stress mouse exercise model.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Gongjin-Dan is a representative traditional Oriental medicine herbal drug that has been used to treat chronic fatigue symptoms for several hundred years. We evaluated the anti-fatigue effects of Gongjin-Dan and the underlying mechanisms in a chronic forced exercise mouse model. METHODS A...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2015.04.001

    authors: Hong SS,Lee JY,Lee JS,Lee HW,Kim HG,Lee SK,Park BK,Son CG

    更新日期:2015-06-20 00:00:00

  • The anti-inflammatory, analgesic and antipyretic activity of Nigella sativa.

    abstract::The aqueous extract of Nigella sativa (N. sativa) was investigated for anti-inflammatory, analgesic and antipyretic activities in animal models. The extract has an anti-inflammatory effect demonstrated by its inhibitory effects on Carrageenan induced paw edema. It also produced significant increase in the hot plate re...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/s0378-8741(01)00216-1

    authors: Al-Ghamdi MS

    更新日期:2001-06-01 00:00:00

  • Botanical remedies of the former Dutch East Indies (Indonesia). Part I: Eumycetes, Pteridophyta, Gymnospermae, Angiospermae (Monocotyledones only).

    abstract::The botanical remedies reported in Heyne's De Nuttige Planten van Nederlandsch-Indië (Volumes 1--IV, 1913--1922) have been screened out of economic botanical context, translated into English and summarized as a table of names, therapeutic indications, plant parts, and available details of preparation and use. ...

    journal_title:Journal of ethnopharmacology

    pub_type: 历史文章,杂志文章

    doi:10.1016/0378-8741(83)90016-8

    authors: Hirschhorn HH

    更新日期:1983-03-01 00:00:00

  • Antidepressant-like effects of Xiaochaihutang in perimenopausal mice.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Xiaochaihutang (XCHT) is a traditional Chinese medicine prescription for thousand years in China. Our previous researches show that XCHT has antidepressant-like effects in several depression models, but effect and mechanism of XCHT in perimenopausal depression are still vague. AIM OF THE...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2019.112318

    authors: Zhang K,Wang Z,Pan X,Yang J,Wu C

    更新日期:2020-02-10 00:00:00

  • Bioassay-guided isolation of active principles from Nigerian medicinal plants identifies new trypanocides with low toxicity and no cross-resistance to diamidines and arsenicals.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Leaves from the plant species studied herein are traditionally used in northern Nigeria against various protozoan infections. However, none of these herbal preparations have been standardized, nor have their toxicity to mammalian cells been investigated. In search of improved and non-toxi...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2017.03.028

    authors: Ebiloma GU,Igoli JO,Katsoulis E,Donachie AM,Eze A,Gray AI,de Koning HP

    更新日期:2017-04-18 00:00:00

  • Evaluation of anti-diarrhoeal and anti-ulcerogenic potential of ethanol extract of Carpolobia lutea leaves in rodents.

    abstract::The effect of ethanol extract of Carpolobia lutea leaves on experimentally induced diarrhoea and ulcers was studied in rodents. The extract (245-735 mg/kg) inhibited small intestinal transit time (15.10-45.03%), castor oil-induced diarrhoea (25.69-43.54%) and fluid accumulation (7.53-34.15%), respectively, as well as ...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2007.01.019

    authors: Nwafor PA,Bassey AI

    更新日期:2007-05-22 00:00:00

  • Traditional Chinese Medicine formula FTZ protects against polycystic ovary syndrome through modulating adiponectin-mediated fat-ovary crosstalk in mice.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:FuFang ZhenZhu TiaoZhi (FTZ) is a hospitalized traditional Chinese medicine herbal formula with documented metabolic benefits. Polycystic ovary syndrome (PCOS) characterized by ovarian dysfunction and insulin resistance represents one of the most common endocrine disorders in close associ...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2020.113587

    authors: Xu Y,Tang J,Guo Q,Xu Y,Yan K,Wu L,Xie K,Zhu A,Rong X,Ye D,Guo J

    更新日期:2021-03-25 00:00:00

  • Cyperus rotundus L.: Traditional uses, phytochemistry, and pharmacological activities.

    abstract:ETHNO-PHARMACOLOGICAL RELEVANCE:Cyperus rotundus L. (Cyperaceae) is a medicinal herb traditionally used to treat various clinical conditions at home such as diarrhea, diabetes, pyresis, inflammation, malaria, and stomach and bowel disorders. Currently, it is one of the most widespread, problematic, and economically dam...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章,评审

    doi:10.1016/j.jep.2015.08.012

    authors: Pirzada AM,Ali HH,Naeem M,Latif M,Bukhari AH,Tanveer A

    更新日期:2015-11-04 00:00:00

  • M3 muscarinic receptor- and Ca2+ influx-mediated muscle contractions induced by croton oil in isolated rabbit jejunum.

    abstract:AIM OF STUDY:Croton oil is the fruit oil of Croton tiglium L., which is well known in folk medicine for the treatment of gastrointestinal (GI) diseases, including constipation, abdominal pain, peptic ulcer, and intestinal inflammation for a long period. This study was to investigate the pharmacological effect of croton...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2010.04.020

    authors: Hu J,Gao WY,Gao Y,Ling NS,Huang LQ,Liu CX

    更新日期:2010-06-16 00:00:00

  • A complex prescription for vitiligo activates mitochondrial ATP synthase-6 expression in B-16 murine melanoma cells.

    abstract::A complex prescription (CP) used traditionally for the treatment of vitiligo was prepared from water extract of eight plant materials. To study the mechanism of this preparation its effect on gene expression of B-16 murine melanoma cells was estimated using differential display method (DDRT-PCR). The results showed th...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2004.03.021

    authors: Li W,Yu W,Dong Q,Wang P,Chen Q

    更新日期:2004-06-01 00:00:00

  • Study of pharmacokinetic profiles and characteristics of active components and their metabolites in rat plasma following oral administration of the water extract of Astragali radix using UPLC-MS/MS.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Astragali radix is one of the well-known traditional Chinese herbal medicine, and possesses various biological functions, such as hepatoprotective and anticancer. In present study, to investigate the metabolism and pharmacokinetics of the major constituents of A. radix, a sensitive ultra-...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2015.04.019

    authors: Shi J,Zheng L,Lin Z,Hou C,Liu W,Yan T,Zhu L,Wang Y,Lu L,Liu Z

    更新日期:2015-07-01 00:00:00

  • Wound healing activity of Calotropis gigantea root bark in rats.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Calotropis gigantea R.Br. (Asclepiadaceae) is a perennial undershrub found chiefly in wastelands throughout India. It has been reported as a traditional folkloric medicine for a variety of alignments. The plant Calotropis gigantea is also used in some parts of India for wound healing in c...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2009.06.007

    authors: Deshmukh PT,Fernandes J,Atul A,Toppo E

    更新日期:2009-08-17 00:00:00

  • Extracts and fractions of Thymus capitatus exhibit antimicrobial activities.

    abstract::Preliminary phytochemical screening of the plant Thymus capitatus exhibited the presence of saponins, resins, flavonoids, essential and fixed oils. Aqueous and ethanolic extracts (10-200 mg/ml) as well as saponin, resin and essential oil of the plant (10-5000 micrograms/ml inhibited the growth of several bacteria and ...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/0378-8741(94)90094-9

    authors: Kandil O,Radwan NM,Hassan AB,Amer AM,el-Banna HA,Amer WM

    更新日期:1994-08-01 00:00:00

  • A standardized extract of Rhynchosia volubilis Lour. exerts a protective effect on benzalkonium chloride-induced mouse dry eye model.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:In contrast to other leguminous plants generally used as food, Rhynchosia volubilis Loureiro, a small soybean with a black seed coat, has been used as a traditional oriental remedy for various human diseases in Eastern Asia. In this study, we demonstrated the protective effect of R. volub...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2017.12.041

    authors: Kang SW,Kim KA,Lee CH,Yang SJ,Kang TK,Jung JH,Kim TJ,Oh SR,Jung SH

    更新日期:2018-04-06 00:00:00

  • Antifertility effects of beta-sitosterol in male albino rats.

    abstract::The effects of beta-sitosterol on fertility, epididymal sperm counts and testicular and accessory reproductive organ weights were evaluated in male albino rats. The effects were studied at two dosages (0.5 and 5 mg/kg per day rat subcutaneously) for 16, 32 and 48 days. The antifertility effect of beta-sitosterol was p...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/0378-8741(91)90066-m

    authors: Malini T,Vanithakumari G

    更新日期:1991-12-01 00:00:00

  • Antiosteoporotic chemical constituents from Er-Xian Decoction, a traditional Chinese herbal formula.

    abstract:AIM OF THE STUDY:Er Xian Decoction (EXD), a traditional Chinese medicine formula, has long been used for the treatment of osteoporosis and menopausal syndrome in China. The present study was designed to investigate the antiosteoporotic constituents of EXD, and evaluate their antiosteoporotic effects in ovariectomized r...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2008.04.009

    authors: Qin L,Han T,Zhang Q,Cao D,Nian H,Rahman K,Zheng H

    更新日期:2008-07-23 00:00:00

  • Protection of mouse brain from paracetamol-induced stress by Centella asiatica methanol extract.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Centella asiatica (CA) is a medicinal herb traditionally used as a brain tonic in Ayurvedic medicine. Various ethnomedical leads revealed the effective use of CA in the treatment of symptoms associated to oxidative stress and inflammation. AIM OF THE STUDY:The aim of this study was to ev...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2019.03.017

    authors: Viswanathan G,Dan VM,Radhakrishnan N,Nair AS,Rajendran Nair AP,Baby S

    更新日期:2019-05-23 00:00:00

  • Effect of Acanthopanax senticosus stem on mast cell-dependent anaphylaxis.

    abstract::We studied the effect of Acanthopanax senticosus stem (ACPS) on mast cell-dependent anaphylaxis. ACPS inhibited compound 48/80-induced systemic anaphylaxis at a dose of 1.0 g/kg by 50%. ACPS also inhibited passive cutaneous anaphylaxis reaction and histamine release from mast cells in a dose-dependent manner, respecti...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/s0378-8741(01)00403-2

    authors: Yi JM,Hong SH,Kim JH,Kim HK,Song HJ,Kim HM

    更新日期:2002-03-01 00:00:00

  • Antimalarial activity of extracts of Malaysian medicinal plants.

    abstract::In vitro and in vivo studies revealed that Malaysian medicinal plants, Piper sarmentosum, Andrographis paniculata and Tinospora crispa produced considerable antimalarial effects. Chloroform extract in vitro did show better effect than the methanol extract. The chloroform extract showed complete parasite growth inhibit...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/s0378-8741(98)00135-4

    authors: Najib Nik A Rahman N,Furuta T,Kojima S,Takane K,Ali Mohd M

    更新日期:1999-03-01 00:00:00

  • Bakera, a herbal steam bath for postnatal care in Minahasa (Indonesia): documentation of the plants used and assessment of the method.

    abstract::Bakera, a steam bath prepared with various plants, is a traditional method used in Minahasa (North Sulawesi, Indonesia) for recuperation after childbirth. Semi-structured interviews were conducted with 14 midwives and 166 mothers in different villages of Minahasa, in order to document the preparation and plants used f...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2007.01.016

    authors: Zumsteg IS,Weckerle CS

    更新日期:2007-05-22 00:00:00

  • Bromelain, the enzyme complex of pineapple (Ananas comosus) and its clinical application. An update.

    abstract::After a short description of the uses of pineapple as folk medicine by the natives of the tropics, the more important new pharmaceutical applications of bromelain, reported between 1975 and 1978, are presented. Although the exact chemical structure of all active components of bromelain is not fully determined, this su...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章,评审

    doi:10.1016/0378-8741(88)90127-4

    authors: Taussig SJ,Batkin S

    更新日期:1988-02-01 00:00:00

  • Phytoestrogenic effect of Inula racemosa Hook f - A cardioprotective root drug in traditional medicine.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Roots of Inula racemosa are used as a cardio protective in Ayurveda in India, being prescribed as a medicine for precordial chest pain, cough and dyspnoea, both singly and as a poly herbal. AIM:Evaluation of Phytoestrogenic activity of the root extracts of Inula racemosa and compounds is...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2017.09.001

    authors: Kalachaveedu M,Raghavan D,Telapolu S,Kuruvilla S,Kedike B

    更新日期:2018-01-10 00:00:00

  • Phytochemical screening of a Warao pharmacopoeia employed to treat gastrointestinal disorders.

    abstract::A three-year medical-ethnobotanical investigation among the Warao of the Orinoco Delta in eastern Venezuela documented a pharmacopoeia of 100 plant species representing 45 families. Warao phytotherapists manipulate these plants in diverse manners to produce 259 remedies of various complexities to treat 52 classes of d...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/0378-8741(91)90183-e

    authors: Wilbert W,Haiek G

    更新日期:1991-08-01 00:00:00

  • Antitubercular activity of Arctium lappa and Tussilago farfara extracts and constituents.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Arctium lappa and Tussilago farfara (Asteraceae) are two plant species used traditionally as antitubercular remedies. The aim of this study was (i) to screen Arctium lappa and Tussilago farfara extracts for activity against Mycobacterium tuberculosis and (ii) to isolate and identify the c...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2014.06.034

    authors: Zhao J,Evangelopoulos D,Bhakta S,Gray AI,Seidel V

    更新日期:2014-08-08 00:00:00

  • An assessment of the Chinese medicinal Dendrobium industry: Supply, demand and sustainability.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:A high proportion of species native to China from the genus Dendrobium (Orchidaceae) have been used as folk medicine for more than 2300 years. The fresh or dried stem of many Dendrobium species are regarded as "superior grade" tonic in Traditional Chinese Medicine (TCM), for their traditi...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章,评审

    doi:10.1016/j.jep.2018.09.001

    authors: Cheng J,Dang PP,Zhao Z,Yuan LC,Zhou ZH,Wolf D,Luo YB

    更新日期:2019-01-30 00:00:00

  • Effects of Curcuma comosa on the expression of atherosclerosis-related cytokine genes in rabbits fed a high-cholesterol diet.

    abstract:AIM OF THE STUDY:Curcuma comosa has been known to have potential use in cardiovascular diseases, but its immunoregulatory role in atherosclerosis development and liver toxicity has not been well studied. We therefore investigated the effects of Curcuma comosa on the expression of atherosclerosis-related cytokine genes ...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2011.01.006

    authors: Charoenwanthanang P,Lawanprasert S,Phivthong-Ngam L,Piyachaturawat P,Sanvarinda Y,Porntadavity S

    更新日期:2011-04-12 00:00:00

  • Antihypertensive and vasorelaxant effects of aqueous extract from Croton schiedeanus Schlecht in rats.

    abstract::Antihypertensive and vasorelaxant effects of treatment with the aqueous extract of Croton schiedeanus Schlecht (AECS) were investigated in anaesthetized spontaneously hypertensive rats (SHR). Intravenous bolus injections of AECS (5-100 mg/kg) elicited dose-dependent decreases in mean arterial pressure (MAP) and heart ...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/s0378-8741(00)00391-3

    authors: Guerrero MF,Carrón R,Martín ML,San Román L,Reguero MT

    更新日期:2001-04-01 00:00:00

  • Inhibition of glucose-induced vascular endothelial growth factor expression by Salvia miltiorrhiza hydrophilic extract in human microvascular endothelial cells: evidence for mitochondrial oxidative stress.

    abstract:AIM OF STUDY:Diabetes mellitus is frequently combined with vascular diseases, which are associated with the expression of vascular endothelial growth factor (VEGF). An approach that can reverse the induction of VEGF by hyperglycemia may potentially benefit the outcome of diabetic patients. Therefore, in the present stu...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2011.07.018

    authors: Qian S,Huo D,Wang S,Qian Q

    更新日期:2011-09-02 00:00:00