The anti-inflammatory, analgesic and antipyretic activity of Nigella sativa.

Abstract:

:The aqueous extract of Nigella sativa (N. sativa) was investigated for anti-inflammatory, analgesic and antipyretic activities in animal models. The extract has an anti-inflammatory effect demonstrated by its inhibitory effects on Carrageenan induced paw edema. It also produced significant increase in the hot plate reaction time in mice indicating analgesic effect. However, N. sativa crude suspension had no effect on yeast induced pyrexia. This study therefore, supports its use in folk medicine both as analgesic and anti-inflammatory agent and calls for further investigations to elucidate its mechanism of action.

journal_name

J Ethnopharmacol

authors

Al-Ghamdi MS

doi

10.1016/s0378-8741(01)00216-1

keywords:

subject

Has Abstract

pub_date

2001-06-01 00:00:00

pages

45-8

issue

1

eissn

0378-8741

issn

1872-7573

pii

S0378-8741(01)00216-1

journal_volume

76

pub_type

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