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Antimalarial activity of extracts of Malaysian medicinal plants.

Abstract：

:In vitro and in vivo studies revealed that Malaysian medicinal plants, Piper sarmentosum, Andrographis paniculata and Tinospora crispa produced considerable antimalarial effects. Chloroform extract in vitro did show better effect than the methanol extract. The chloroform extract showed complete parasite growth inhibition as low as 0.05 mg/ml drug dose within 24 h incubation period (Andrographis paniculata) as compared to methanol extract of drug dose of 2.5 mg/ml but under incubation time of 48 h of the same plant spesies. In vivo activity of Andrographis paniculata also demonstrated higher antimalarial effect than other two plant species.

journal_name

J Ethnopharmacol

journal_title

Journal of ethnopharmacology

authors

Najib Nik A Rahman N,Furuta T,Kojima S,Takane K,Ali Mohd M

doi

10.1016/s0378-8741(98)00135-4

keywords:

subject

Has Abstract

pub_date

1999-03-01 00:00:00

pages

249-54

issue

3

eissn

0378-8741

issn

1872-7573

pii

S0378874198001354

journal_volume

64

pub_type

杂志文章

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