Abstract：
:The possibility that phenylalkylamines (cathinone and cathine) of khat, like amphetamines, are amine oxidase inhibitors with clinical significance is evaluated. Results show that khat chewing induces a significant increase in blood pressure, body temperature and urinary catecholamines in khat naive subjects. On the other hand, in habitual consumers a significant enhancement only of blood pressure is observed. Urinary concentrations of vanilmandelic acid show an inhibitory trend in both groups of subjects. This has been related to a decrease in catecholamine deamination. In fact, oxidative deamination of benzylamine catalyzed by beef plasma amine oxidase is non-competitively inhibited in vitro by cathinone (Ki = 0.05 mM) and cathine (Ki = 10 mM) as well as by amphetamine (Ki = 7.9 mM).
journal_name
J Ethnopharmacoljournal_title
Journal of ethnopharmacologyauthors
Nencini P,Amiconi G,Befani O,Abdullahi MA,Anania MCdoi
10.1016/0378-8741(84)90097-7subject
Has Abstractpub_date
1984-06-01 00:00:00pages
79-86issue
1eissn
0378-8741issn
1872-7573pii
0378-8741(84)90097-7journal_volume
11pub_type
杂志文章abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Nymphaea hybrida Peck is used as a traditional medicinal herb for treating pain and inflammatory diseases, and known for its ornamental value and as a hot drink. However, the effects of N. hybrida polar fractions on lipopolysaccharide (LPS)-induced in vitro inflammation model and acute in...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2020.113698
更新日期：2021-04-06 00:00:00
abstract：:Recent research suggests that, in addition to the well-documented occurrence of significant quantities of cocaine and related alkaloids in a limited number of species, the genus Erythroxylon will prove to be a rich source of tropane alkaloids. These bases are esters of a range of acids with tropine, 3 alpha, 6 beta-di...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/0378-8741(81)90057-x
更新日期：1981-03-01 00:00:00
abstract：AIM OF THE STUDY:Previous studies in our laboratory revealed the neuroprotective effect of modified Yeoldahanso-tang (MYH) in models of Parkinson׳s disease (PD). In this study, we investigated another traditional Korean herbal formula, modified Chungsimyeolda-tang (termed DG), as a potential treatment for PD. Chungsimy...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2014.11.007
更新日期：2015-01-15 00:00:00
abstract：:The plant, Typhonium flagelliforme (Araceae), commonly known as the "rodent tuber" in Malaysia, is often used as an essential ingredient of herbal remedies for alternative cancer therapies. The hexane extract of this plant was evaluated for cytotoxic activity against in vitro culture on P388 murine leukaemia cells and...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/s0378-8741(01)00274-4
更新日期：2001-09-01 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:The genus Psoralea (Fabaceae) harbours 105 accepted species that are extensively used by local peoples and medicinal practitioners of China, India, and other countries for treatment of tooth decay, psoriasis, leucoderma, leprosy, kidney problems, tuberculosis, indigestion, constipation an...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章,评审
doi：10.1016/j.jep.2018.11.036
更新日期：2019-03-25 00:00:00
abstract：:The present study was planned to investigate the ethnoveterinary methods practiced by the owners of pneumatic-cart pulling camels in Faisalabad Metropolis (Pakistan). During a 7-year-period (November 1992-November 1999), 200 owners of draught camels working in the city were interviewed. Information concerning the ethn...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2004.11.008
更新日期：2005-02-28 00:00:00
abstract：AIM OF THE STUDY:Around the world, Tilia species have been used in traditional medicine for their properties as tranquilizer. Furthermore, Mexican species of Tilia have been grouped as Tilia americana var. mexicana, but their specific content in flavonoids is poorly described. In this study, inflorescences of Mexican T...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2009.09.044
更新日期：2010-01-08 00:00:00
abstract：:One of the significant characteristics of traditional Chinese medicine is the use of insects, other terrestrial arthropods and their products as drugs. In the present work, the extract of housefly (Musca domestica) larvae was studied by an agar well diffusion assay and minimum bactericidal concentration (MBC) determin...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2006.11.015
更新日期：2007-05-04 00:00:00
abstract：:It is well established that nitric oxide (NO) and superoxide radicals play pivotal roles in the pathogenesis of inflammatory diseases and fever. This study is undertaken to address whether the methanol extract of Spiraea prunifolia var. simpliciflora root, a traditional medicine as an antipyretic, modulates the genera...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/s0378-8741(99)00101-4
更新日期：1999-12-15 00:00:00
abstract：:Murdannia bracteata has been used as a Taiwanese folk medicine for its anti-inflammatory properties. However, neither its active ingredients nor its anti-inflammatory actions are well defined. Nitric oxide (NO), overproduced by activated macrophages via inducible NO synthase (iNOS), is suggested to be a significant pa...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2007.02.025
更新日期：2007-06-13 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:The rhizome of Atractylodes lancea (AL, Compositae, Chinese name: Cangzhu; Japanese name: Sou-ju-tsu) has been used traditionally for the treatment of various diseases such as digestive disorders, rheumatic diseases, and influenza in China, Korea and Japan. The crude AL and AL bran-proces...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2014.10.066
更新日期：2015-02-03 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Akebiae Fructus, a Tujia minority folk medicine and a well-known traditional Chinese medicine for soothing the liver, regulating Qi, promoting blood circulation and relieving pain, is widely used in the treatment of primary dysmenorrhea. However, little is known about its underlying mecha...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2020.113763
更新日期：2020-12-28 00:00:00
abstract：BACKGROUND AND AIM:Chronic glomerulonephritis (CGN) is a primary glomerular disease that is related to immune-mediated inflammatory diseases. Qi Teng Xiao Zhuo granules have been proposed as a prescription of traditional Chinese medicine for treatment of CGN, but the comprehensive molecular mechanism underlying this th...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2016.08.011
更新日期：2016-12-04 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:A high proportion of species native to China from the genus Dendrobium (Orchidaceae) have been used as folk medicine for more than 2300 years. The fresh or dried stem of many Dendrobium species are regarded as "superior grade" tonic in Traditional Chinese Medicine (TCM), for their traditi...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章,评审
doi：10.1016/j.jep.2018.09.001
更新日期：2019-01-30 00:00:00
abstract：:In view of the extensive use of Eugenia uniflora in folk medicine, different extracts of dried and fresh leaves of the plant were assayed to test its possible pharmacological activities. The infusion of fresh leaves had a highly significant anti-inflammatory effect when administered p.o. to rats 1 h before subplantar ...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/0378-8741(94)01178-8
更新日期：1994-12-01 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Tetrastigma hemsleyanum Diels et Gilg, known as Sanyeqing in China, was an extensively used folk Chinese herbal medicine. This plant had been validated to be highly effective for treating high fever, pneumonia, hepatitis, gastritis, cervicitis, lymphatic tuberculosis, septicemia, and vira...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章,评审
doi：10.1016/j.jep.2021.113836
更新日期：2021-01-16 00:00:00
abstract：AIM OF THE STUDY:For identification of the active constituents we investigated the anticancer activity of cardenolides from Streptocaulon tomentosum Wight & Arn. (Asclepiadaceae) and from Nerium oleander L. (Apocynaceae) which are both used against cancer in the traditional medicine in their region of origin. MATERIAL...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2011.01.038
更新日期：2011-04-12 00:00:00
abstract：AIM OF THE STUDY:To analyse the pro-ejaculatory properties of the proverbial Mexican plant oquichpatli, Senecio cardiophyllus, in an animal model for the study of ejaculation in spinal and anaesthetised male rats. MATERIALS AND METHODS:The aqueous crude extract of Senecio cardiophyllus (at 0.4, 1.2 and 4 mg/kg) was i....
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2009.09.006
更新日期：2009-12-10 00:00:00
abstract：AIM OF THE STUDY:Experiments were conducted to understand the therapeutic properties such as anti-inflammatory and anti-pyretic activities of biologically active extract isolated from whole earthworm (Lampito mauritii, Kinberg). MATERIALS AND METHODS:Inflammation in the hind paw of Wistar albino rat, Rattus norvegicus...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2008.10.021
更新日期：2009-01-21 00:00:00
abstract：:We evaluate the mode of action of verbascoside obtained from Buddleja cordata against Staphylococcus aureus by killing kinetics and incorporation of precursors methods. Verbascoside induced lethal effect on S. aureus, by affecting protein synthesis and inhibiting leucine incorporation. ...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/s0378-8741(98)00203-7
更新日期：1999-07-01 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:From ancient time human beings have used different plants, animals and minerals to prevent and treat various diseases. In this respect, plants have been of particular importance. Ethnobotany is the science of reviewing how indigenous people and local tribes have used their regional plants...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2014.04.003
更新日期：2014-05-28 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:In Brazil, a phytotherapeutic preparation produced from a standardized tincture of Cinchona calisaya Weddel such that each mL of product contains 400µg of quinine, known in Portuguese as Água Inglesa(®) (English water), is indicated by the manufacturer as a tonic, appetite stimulant, and ...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2014.07.038
更新日期：2014-09-29 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Although the increased usage of herbal medicine leading to herb-drug interactions is well reported, the mechanism of such interactions between herbal medicines with conventionally prescribed drugs such as warfarin is not yet fully understood. Our previous rat in vivo study demonstrated th...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2014.04.047
更新日期：2014-07-03 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Zanthoxylum alatum is used in traditional medicinal systems for number of disorders like cholera, diabetes, cough, diarrhea, fever, headache, microbial infections, toothache, inflammation and cancer. The aim of the present study was to evaluate Zanthoxylum alatum stem bark for its cytotox...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2013.12.039
更新日期：2014-02-27 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Passiflora incarnata Linnaeus (Passiflora incarnata) was established as a medicinal plant in Europe in the middle of the 19th century. Since then, it has been used for the treatment of anxiety, sleep disorders and restlessness in Western European phytotherapy. This study provides insights...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2018.11.022
更新日期：2019-03-01 00:00:00
abstract：:Clerodendron colebrookianum Walp (family, Verbenaceae) has been used as a home remedy by the Mizo people of north eastern (NE) region of India in their folklore medicine as a cardioprotective (mainly against high blood pressure) agent. The scientific basis for their use has yet to be established. Therefore, in this in...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2003.09.022
更新日期：2004-01-01 00:00:00
abstract：:The ethanol extract of the plant Hippocratea excelsa was examined for its anti-inflammatory effects using several animal models. It produced significant inhibition of carrageenan-induced paw edema and reduced the weight of cotton pellet-induced granuloma at doses of 25-100 mg/kg. The extract was found to exert a prote...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/0378-8741(95)01257-e
更新日期：1995-07-07 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Indigofera argentea Burm. f.; commonly known as neel, jantari, hathio; is traditionally used for the treatment of headache, fever, inflammation and body pain. Local communities also used this plant for the treatment of malaria, jaundice, vertigo and gastric disorders. AIM OF THE STUDY:Th...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2020.112966
更新日期：2020-09-15 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Berberine is generally extracted from Rhizoma Coptidis (Coptis chinensis Franch), a traditional Chinese medicine, which can be used in the treatment of intestinal diseases, respiratory infections and cardiovascular diseases. Berberine is especially effective for the treatment of gastroint...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2020.113206
更新日期：2021-01-10 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:The development of selective inhibitors of monoamine oxidase B (MAO-B) has been essential in treating Parkinson's disease. However, the apparent hepatotoxicity and drug-drug interactions of current inhibitors accentuate the need for the development of novel pharmacotherapies. Crossyne gut...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2019.112305
更新日期：2020-02-10 00:00:00
