Abstract:
:One of the significant characteristics of traditional Chinese medicine is the use of insects, other terrestrial arthropods and their products as drugs. In the present work, the extract of housefly (Musca domestica) larvae was studied by an agar well diffusion assay and minimum bactericidal concentration (MBC) determination for detection of antimicrobial activity and by MTT assay method to test its in vitro anti-tumor activity. In our studies, the extract inhibited six tested bacterial pathogens and Escherichia coli Jm109, a gene-modified strain resistant to ampicillin with the MBCs ranging from 200 to 1600 microg/ml, while Gram-positive bacteria were more sensitive than Gram-negative bacteria. The extract showed high in vitro anti-tumor activity against human colon cancer cell line CT26 with the IRs ranging from 62 to 89%. The extract of housefly larvae inoculated with Shigella dysenteriae 51302 exhibited higher antibacterial activity and in vitro anti-tumor activity than that of native larvae, which may indicate the same principle involved in the use of Bombyx mori larvae infected with silk moth fungus Beauveria bassiana and Hepialis larvae infected with Cordiceps fungus in the traditional Chinese medicine. Both extracts did not show any coagulation activity and haemolysis activity against rabbit erythrocytes at 500 and 1000 microg/ml. The results support its use in the traditional Chinese medicine, and warrant the further identification of the active molecule in the housefly larvae.
journal_name
J Ethnopharmacoljournal_title
Journal of ethnopharmacologyauthors
Hou L,Shi Y,Zhai P,Le Gdoi
10.1016/j.jep.2006.11.015subject
Has Abstractpub_date
2007-05-04 00:00:00pages
227-31issue
2eissn
0378-8741issn
1872-7573pii
S0378-8741(06)00612-Xjournal_volume
111pub_type
杂志文章abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Danhong injection (DHI) is a traditional Chinese medicine injection that has been widely used in therapy for cardiovascular diseases. However, neither its mechanism nor its active constituents are clearly understood. AIM OF THE STUDY:Our research aimed at identifying the anti-inflammator...
journal_title:Journal of ethnopharmacology
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更新日期:2015-11-04 00:00:00
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journal_title:Journal of ethnopharmacology
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更新日期:2021-01-30 00:00:00
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journal_title:Journal of ethnopharmacology
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doi:10.1016/j.jep.2008.07.022
更新日期:2008-10-28 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Zanthoxylum bungeanum Maxim seed (ZBMS) has been used in Traditional Chinese Medicine (TCM) as an ingredient of polyherbal formulations for the treatment of inflammation and asthma. The aim of this study was to analyze the major composition and to evaluate the anti-asthma activity of ZBMS...
journal_title:Journal of ethnopharmacology
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doi:10.1016/j.jep.2014.01.013
更新日期:2014-03-28 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Radix paeoniae rubra, also known as chishao (CS), is a frequently used traditional Chinese medicine that can promote blood circulation to remove blood stasis. It has been widely used for the prevention and treatment of cardiovascular diseases in China. Although terpene glycoside (TG), the...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2017.05.028
更新日期:2017-07-12 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Epilobium species are generally known as "Yakı Otu" in Turkey, which mens "plaster herb" in English. Young shoots of Epilobium angustifolium L., Epilobium stevenii Boiss., and Epilobium hirsutum L. are consumed as salad or meal. These species have been used as a poultice for the treatment...
journal_title:Journal of ethnopharmacology
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更新日期:2020-11-15 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:The pharmacological effect derived from herb-herb interaction is important to constitute the prescription especially in traditional oriental medicine. The relationship of two medicinal herbs is called "couplet medicinals" which is used in pair for the purpose of enhancing the therapeutic ...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2018.03.036
更新日期:2018-06-28 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Tecoma stans is traditionally used by several ethnical groups in Mexico and Central America to treat diabetes. This species is mentioned in the majority of the ethnopharmacological studies compiled in Mexico focused in medicinal plants used as anti-diabetic treatment. AIM OF THE STUDY:Re...
journal_title:Journal of ethnopharmacology
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更新日期:2016-06-05 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Lizhong Decoction (LZD) is a classical prescription firstly recorded in "Shanghan Lun". It has been used to clinically treat ulcerative colitis (UC) for thousands of years. However, its mechanism is not clear up to now. AIM OF THE STUDY:The goal of this study was to assess the ameliorati...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
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更新日期:2020-09-15 00:00:00
abstract::Biochemical analysis of a selected sample of the Hausa (northern Nigeria) medicinal flora is presented in order to assess potential chemotherapeutic values. Laboratory investigation, supplemented by previously published phytochemical constituent analyses of pertinent taxa, suggests that a number of disorders can be ef...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/0378-8741(81)90021-0
更新日期:1981-07-01 00:00:00
abstract::Ethanolic extracts of 18 medicinal plants traditionally used in Jordan for the treatment of gastric ulcers were evaluated for their possible anti-ulcer activity. Among the tested plants, 12 extracts lowered the severity of ethanol-induced gastric damage in rats with curative ratios ranging from 62.9 to 99.5%. The most...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/s0378-8741(98)00126-3
更新日期:1999-11-30 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:The Renshen Shouwu capsule (RSSW) is a patented Traditional Chinese Medicine (TCM), that has been proven to improve memory and is widely used in China to apoplexy syndrome and memory deficits. To investigate the neuroprotective and therapeutic effect of the Renshen Shouwu standardized ext...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2015.02.027
更新日期:2015-05-13 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Gonorrhea is a sexually transmitted disease (STD), which originates from bacteria, Neisseria gonorrhoeae. It is still one of the major health problems worldwide in both men and women. Many medicinal plants have been recorded in Thai folk medicine for relieving STD but there is no scientif...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2009.01.036
更新日期:2009-04-21 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Spatholobus suberectus Dunn is a traditional Chinese medicine (TCM) that can activate blood, dispel stasis, inhibit platelet aggregation, and stimulate hematopoiesis, and thereby treat anemia and diseases related to blood stasis syndrome (BSS). However, its hematopoiesis-stimulating activ...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2019.111938
更新日期:2019-08-10 00:00:00
abstract::Chronic users of non-steroidal anti-inflammatory drugs frequently develop ulcerative lesions in their intestines. The purpose of the present study was to investigate whether eupatilin, an active ingredient derived from Artemisia plants, prevents this side effect in vitro. Extracts of the whole herb of Artemisia asiati...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2008.03.010
更新日期:2008-06-19 00:00:00
abstract::meenakshi Cissampelos pareira Linn. is one of the folk medicinal plants commonly used as antifertility agent in some places of India. The aim of the present study was to evaluate the validity of the antifertility effect of the leaf extract. Cissampelos pareira leaf extract, when administered orally, altered the estrou...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2007.01.023
更新日期:2007-05-22 00:00:00
abstract::The purpose of this research was to study the anti-hyperglycemic effect of 28 medicinal plants used in the treatment of diabetes mellitus. Each plant was processed in the traditional way and intragastrically administered to temporarily hyperglycemic rabbits. The results showed that eight out of the 28 studied plants s...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/s0378-8741(98)00020-8
更新日期:1998-06-01 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Pfaffia glomerata roots are widely used in Brazil to treat various pathological conditions, particularly psychological disorders. 20-hydroxyecdysone, a phytosteroid present in the plant, can promote greater body resistance against exogenous and endogenous stressors. The objective of this ...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2020.113599
更新日期:2021-03-01 00:00:00
abstract::The lipid lowering activity (LLA) of Phyllanthus niruri has been studied in triton and cholesterol fed hyperlipemic rats. Serum lipids were lowered by P. niruri extract orally fed (250 mg/kg b.w.) to the triton WR-1339 induced hyperlipemic rats. Chronic feeding of this drugs (100 mg/kg b.w.) in animals simultaneously ...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/s0378-8741(02)00136-8
更新日期:2002-09-01 00:00:00
abstract::From September 1990 to December 1994, the authors conducted an ethnobotanical survey within the population of Martinique. Two hundred and sixty-one plants used for medicinal purposes were gathered. It was possible to identify 251 species (96%). Traditional medicinal practices, although threatened by the modern pharmac...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/0378-8741(96)01425-0
更新日期:1996-09-01 00:00:00
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journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2020.113691
更新日期:2021-04-06 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Solanum torvum (Solanaceae) is a plant currently used in Cameroon ethnomedicine for the treatment of stomach ailments. AIM OF THE STUDY:The present study was undertaken to determine the anti-ulcer potential of the aqueous and methanol extracts from the leaves of Solanum torvum. MATERIAL...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2008.06.008
更新日期:2008-09-02 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:The roots of Mirabilis himalaica have been used in Tibetan folk medicine for treatment of uterine cancer, nephritis edematous, renal calculus and arthrodynia. In our previous work, the ethanol extract of roots had shown potent cytotoxicity against human cancer cells. However, no informati...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2014.05.034
更新日期:2014-08-08 00:00:00
abstract:AIM OF THE STUDY:The aim of this study was to evaluate the acute and chronic effects of OpunDia (Opuntia ficus-indica) in obese pre-diabetic men and women. MATERIALS AND METHODS:This double-blind placebo controlled study included participants (age range of 20-50 years) randomly assigned to one of the two groups and gi...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jep.2010.05.047
更新日期:2010-08-09 00:00:00
abstract::With cancer deaths increasing, the initiation, pathophysiology and curative management of cancer is receiving increasing attention. Traditional therapies such as surgery and chemoradiotherapy are often accompanied by suppression of host immunity, which increase the risk of metastasis. Astragalus membranceus (AM) is co...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章,评审
doi:10.1016/j.jep.2020.112797
更新日期:2020-08-10 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:To evaluate the hepatoprotective effect of the root and rhizome of Rhubarb (Rhei Radix et Rhizoma) against α-naphthylisothiocyanate (ANIT)-induced liver injury using metabolic profile of bile acids (BAs) along with biochemical parameters and histological alterations. MATERIALS AND METHOD...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2012.09.049
更新日期:2012-12-18 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:The root of Peucedanum japonicum Thunberg is traditionally used to treat coughs, colds, headache and inflammatory diseases in Korea and Japan. Its effects on allergic lung inflammation have not been investigated. AIM OF THE STUDY:To investigate the anti-asthmatic effects of Peucedanum ja...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2017.09.006
更新日期:2018-01-30 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Fructus Arctii is the dried ripe fruit of Arctium lappa L. (family Asteraceae). It is a well-known Chinese Materia Medica that was included in the Chinese pharmacopoeia because of its traditional therapeutic actions, such as heat removal, detoxification, and elimination of swelling. Since...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2020.112773
更新日期:2020-06-12 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:The Kuki-Chin is a composite ethnolinguistic group made up of many distinct groups and subgroups that are linked by a common history, culture, and population distribution in the Kuki-Chin region, shared geopolitically by Bangladesh, India, and Myanmar. This region is shown to be in a hots...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章,评审
doi:10.1016/j.jep.2019.112415
更新日期:2020-04-06 00:00:00
abstract::Four taxoids (taxusin, baccatin VI, baccatin III and 1beta-hydroxybaccatin I) and five lignans (lariciresinol, taxiresinol, 3'-demethylisolariciresinol-9'-hydroxyisopropylether, isolariciresinol and 3-demethylisolariciresinol) were isolated from the heartwood of Taxus baccata L. (Taxaceae) growing in Turkey through ch...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2003.09.005
更新日期:2003-12-01 00:00:00