Antihyperglycemic activity of Momordica cymbalaria in alloxan diabetic rats.

Abstract:

:Aqueous, ethanolic and hexane fractions of Momordica cymbalaria fruits were prepared and given individually at different doses to different batches of rats (both normal and alloxan diabetic rats) after an overnight fast. The blood glucose levels were measured at 0, 1, 3, 5 and 7 h after the treatment. The aqueous extract of Momordica cymbalaria at a dosage of 0.5 g/kg b.w. is showing maximal blood glucose lowering effect in diabetic rats. The same dosage did not produce any hypoglycemic activity in normal rats. The antihyperglycemic activity of Momordica cymbalaria fruit was compared with the treatment of Glibenclamide, an oral hypoglycemic agent.

journal_name

J Ethnopharmacol

authors

Rao BK,Kesavulu MM,Apparao C

doi

10.1016/s0378-8741(01)00324-5

keywords:

subject

Has Abstract

pub_date

2001-11-01 00:00:00

pages

67-71

issue

1

eissn

0378-8741

issn

1872-7573

pii

S0378874101003245

journal_volume

78

pub_type

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