当前位置： SCI文献检索 > JOURNAL OF ETHNOPHARMACOLOGY期刊下所有文献 > Prevention of hepatic injury by a traditional Chinese formulation, BJ-JN, in mice treated with Bacille-Calmette-Guérin and lipopolysaccharide.

Prevention of hepatic injury by a traditional Chinese formulation, BJ-JN, in mice treated with Bacille-Calmette-Guérin and lipopolysaccharide.

Abstract：

:The hepatoprotective effects of BJ-JN (a traditional Chinese formulation) were evaluated in Bacille-Calmette-Guérin and lipopolysaccharide (BCG/LPS)-induced immunological liver injury (ILI) in mice. BJ-JN (0.75, 1.5, 3 g/kg) was administered via gavage daily for 10 days. Liver index (liver weight/body weight), serum levels of alanine aminotransferase (ALT), hepatic nitric oxide (NO), malondialdehyde (MDA) content, superoxide dismutase (SOD) activity, splenocyte proliferation, production of tumor necrosis factor-alpha (TNF-alpha) and interleukin-1 (IL-1) by peritoneal macrophages, and histopathologic changes of the liver were evaluated following the 10 days treatment. BJ-JN (0.75, 1.5, 3 g/kg) effectively reduced the BCG/LPS-induced elevated liver index, serum ALT levels, hepatic NO and MDA content, and restored hepatic SOD activity in ILI mice. BJ-JN treatment also alleviated diminished splenocyte proliferation induced by concanavalin A (ConA) and repressed abnormally high levels of TNF-alpha and IL-1 from peritoneal macrophages. The histopathological analysis suggested that BJ-JN reduced the degree of liver injury of ILI mice. These results suggest that BJ-JN has a protective and therapeutic effect on ILI mice, which might be associated with its antioxidant properties, ability to reduce NO production and immunoregulatory function.

journal_name

J Ethnopharmacol

journal_title

Journal of ethnopharmacology

authors

Zou Y,Yang Y,Li J,Li W,Wu Q

doi

10.1016/j.jep.2006.04.006

subject

Has Abstract

pub_date

2006-10-11 00:00:00

pages

442-8

issue

3

eissn

0378-8741

issn

1872-7573

pii

S0378-8741(06)00180-2

journal_volume

107

pub_type

杂志文章

相关文献

JOURNAL OF ETHNOPHARMACOLOGY文献大全
  • Prevention of experimental diabetes by Uncaria tomentosa extract: Th2 polarization, regulatory T cell preservation or both?

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Uncaria tomentosa (Willd.) DC (Rubiaceae) is a species native to the Amazon rainforest and surrounding tropical areas that is endowed with immunomodulatory properties and widely used around the world. In this study we investigated the immunomodulatory potential of Uncaria tomentosa (UT) a...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2011.06.021

    authors： Domingues A,Sartori A,Golim MA,Valente LM,da Rosa LC,Ishikawa LL,Siani AC,Viero RM

    更新日期：2011-09-01 00:00:00

  • Intestinal smooth muscle spasmolytic actions of the aqueous extract of the roots of Taverniera abyssinica.

    abstract：:A room temperature aqueous extract of the roots of Taverniera abyssinica antagonized the contractile responses of the guinea-pig ileum to acetylcholine and histamine. The extract also relaxed the smooth muscle of the rabbit duodenum, abolished the pendular contractions and antagonized the effects of acetylcholine and ...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/0378-8741(90)90021-k

    authors： Noamesi BK,Bogale M,Dagne E

    更新日期：1990-08-01 00:00:00

  • Effects of cryptolepine alone and in combination with dipyridamole on a mouse model of arterial thrombosis.

    abstract：:The effects of cryptolepine alone and in combination with other antiplatelet agents have been investigated using a mouse model of arterial thrombosis. Intraperitoneal premedication with crytolepine produced 25% maximal protection at 1 mg/kg while dipyridamole producedd a 20% maximal effect at 2 mg/kg. Higher doses of ...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/0378-8741(89)90086-x

    authors： Oyekan AO,Okafor JP

    更新日期：1989-11-01 00:00:00

  • Treatment of osteoarthritis with a herbomineral formulation: a double-blind, placebo-controlled, cross-over study.

    abstract：:The clinical efficacy of a herbomineral formulation containing roots of Withania somnifera, the stem of Boswellia serrata, rhizomes of Curcuma longa and a zinc complex (Articulin-F), was evaluated in a randomized, double-blind, placebo controlled, cross-over study in patients with osteoarthritis. After a one-month sin...

    journal_title：Journal of ethnopharmacology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/0378-8741(91)90167-c

    authors： Kulkarni RR,Patki PS,Jog VP,Gandage SG,Patwardhan B

    更新日期：1991-05-01 00:00:00

  • Anticancer potential of Hericium erinaceus extracts against human gastrointestinal cancers.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Hericium is a genus of mushrooms (fungus) in the Hericiaceae family. Hericium erinaceus (HE) has been used for the treatment of digestive diseases for over 2000 years in China. HE possesses many beneficial functions such as anticancer, antiulcer, antiinflammation and antimicrobial effects...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2014.03.003

    authors： Li G,Yu K,Li F,Xu K,Li J,He S,Cao S,Tan G

    更新日期：2014-04-28 00:00:00

  • Immune modulation of a lipid-soluble extract of Pinellia pedatisecta Schott in the tumor microenvironment of an HPV+ tumor-burdened mouse model.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Pinellia pedatisecta Schott extract (PE), a traditional Chinese medicine, has been used to reduce swelling, dry dampness and suppress cervical tumors. AIMS:To evaluate the roles of PE in the regulation of anti-tumor effects and the cellular immune response in the tumor microenvironment. ...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2018.04.037

    authors： Huang H,Zhang M,Yao S,Zhang M,Peng J,with the Pinellia pedatisecta (PE) advisory group.

    更新日期：2018-10-28 00:00:00

  • Anxiolytic effect of a herbal medicine, yokukansan, in aged rats: involvement of serotonergic and dopaminergic transmissions in the prefrontal cortex.

    abstract：AIM OF THE STUDY:Aging is thought to affect emotions including anxiety, and a herbal medicine, yokukansan (YKS), is used to treat emotional disturbances associated with age-related neurodegenerative disorders such as Alzheimer's disease, but its pharmacological properties have not been fully understood. The present stu...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2009.09.048

    authors： Mizoguchi K,Tanaka Y,Tabira T

    更新日期：2010-01-08 00:00:00

  • Traditional uses of some medicinal plants in Malatya (Turkey).

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:This study has identified not only the wild plants collected for medical purposes by local people of Malatya Province in the Eastern Anatolia Region, but also the uses and local names of these plants. It tried to provide a source for researchers studying in ethnobotany, pharmacology and c...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2012.12.054

    authors： Tetik F,Civelek S,Cakilcioglu U

    更新日期：2013-03-07 00:00:00

  • Effects of the total flavonoid extract of Xiaobuxin-Tang on depression-like behavior induced by lipopolysaccharide and proinflammatory cytokine levels in mice.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Xiaobuxin-Tang (XBXT), a traditional Chinese herbal decoction, has been used for the treatment of depressive disorders from ancient clinic. The aim of the study was to explore the involvement of inflammation or inflammatory markers in the antidepressant-like effects of XBXT-2. MATERIALS ...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2015.01.022

    authors： An L,Li J,Yu ST,Xue R,Yu NJ,Chen HX,Zhang LM,Zhao N,Li YF,Zhang YZ

    更新日期：2015-04-02 00:00:00

  • The protective effects of Phyllanthus emblica Linn. extract on ethanol induced rat hepatic injury.

    abstract：:This study was undertaken to investigate the protective effects of Phyllanthus emblica Linn. (PE) extract on ethanol induced rat hepatic injury. PE (0.5 and 1 mg/ml) increased cell viability of rat primary cultured hepatocytes being treated with ethanol (96 microl/m) by increasing % MTT and decreasing the release of t...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2006.03.035

    authors： Pramyothin P,Samosorn P,Poungshompoo S,Chaichantipyuth C

    更新日期：2006-10-11 00:00:00

  • Effect of a herbal protein, CI-1, isolated from Cajanus indicus on immune response of control and stressed mice.

    abstract：:The effect of a herbal protein, CI-1, purified from the leaves of Cajanus indicus was evaluated as a probable immunomodulator on immune response in control and stressed mice. In mice, sensitized with sheep red blood cells (SRBC), CI-1 enhanced IgG level by 28% over control (P < 0.05). Primary and secondary antibody re...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/s0378-8741(99)00046-x

    authors： Datta S,Sinha S,Bhattacharyya P

    更新日期：1999-11-30 00:00:00

  • Pharmacological basis for use of Lychnophora trichocarpha in gouty arthritis: anti-hyperuricemic and anti-inflammatory effects of its extract, fraction and constituents.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:The ethanolic extract of Lychnophora trichocarpha Spreng. is used in Brazilian folk medicine to treat bruise, pain and inflammatory diseases. AIM OF THE STUDY:The present study aimed at investigating whether ethanolic extract of L. trichocarpha, its ethyl acetate fraction and its main bi...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2012.06.012

    authors： de Souza MR,de Paula CA,Pereira de Resende ML,Grabe-Guimarães A,de Souza Filho JD,Saúde-Guimarães DA

    更新日期：2012-08-01 00:00:00

  • Traditional medicine in Bulamogi county, Uganda: its practitioners, users and viability.

    abstract：:Traditional medicine (TM) in Bulamogi (Uganda) is holistic, providing treatments for physical illnesses as well as psycho-spiritual ones. People use it to prevent and eliminate the effects of witchcraft, to appease spirits and to cure chronic illnesses. The traditional medicine practitioners (TMPs) are numerous and ha...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/s0378-8741(02)00378-1

    authors： Tabuti JR,Dhillion SS,Lye KA

    更新日期：2003-03-01 00:00:00

  • Recent trends in research into African medicinal plants.

    abstract：:Recent trends in research into African medicinal plants show that while ethnobotanical surveys continue, there is an appreciable increase in research activity in the area of bioactivity of natural products. The biological areas most researched include antimicrobial, molluscicidal, toxicity tests and antitumour in decr...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章,评审

    doi：10.1016/0378-8741(93)90017-y

    authors： Sofowora A

    更新日期：1993-03-01 00:00:00

  • In vitro antiplasmodial activity and cytotoxicity of 33 West African plants used for treatment of malaria.

    abstract：:Thirty-three plants commonly used in West tropical Africa by traditional healers for the treatment of malaria were collected and ethanolic extracts were obtained by decoction. The antiplasmodial activity of extracts was evaluated in vitro against the chloroquine-resistant FcB1 strain of Plasmodium falciparum. Cytotoxi...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2005.01.004

    authors： Zirihi GN,Mambu L,Guédé-Guina F,Bodo B,Grellier P

    更新日期：2005-04-26 00:00:00

  • Traditional plants used for medicinal purposes by local communities around the Northern sector of Kibale National Park, Uganda.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:The study was done to establish medicinal plants used in the treatment of various diseases by the people in the Northern sector of Kibale National Park in western Uganda. It was also aimed at establishing the plant parts used and the mode of preparation of remedies. These plants create a ...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2011.04.044

    authors： Namukobe J,Kasenene JM,Kiremire BT,Byamukama R,Kamatenesi-Mugisha M,Krief S,Dumontet V,Kabasa JD

    更新日期：2011-06-14 00:00:00

  • Evaluation of potential herb-drug interactions between oseltamivir and commonly used anti-influenza Chinese medicinal herbs.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:According to Traditional Chinese Medicine theory, influenza is categorized as a warm disease or Wen Bing. The Wen Bing formulas, such as Yin-Qiao-San and Sang-Ju-Yin, are still first-line herbal therapies in combating variant influenza virus. To continue our study on the pharmacokinetic a...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2019.112097

    authors： Zhang Y,Lyu C,Fong SYK,Wang Q,Li C,Ho NJ,Chan KS,Yan X,Zuo Z

    更新日期：2019-10-28 00:00:00

  • Efficacy and safety of Pueraria candollei var. mirifica (Airy Shaw & Suvat.) Niyomdham for menopausal women: A systematic review of clinical trials and the way forward.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Pueraria candollei var. mirifica (Airy Shaw & Suvat.) Niyomdham (commonly termed P. mirifica, PM) growing in upland Thailand has a long history as a postmenopausal rejuvenant therapy for indigenants. Its amelioration of menopause symptoms in clinical trials was assessed. MATERIALS AND ME...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jep.2018.01.028

    authors： Kongkaew C,Scholfield NC,Dhippayom T,Dilokthornsakul P,Saokaew S,Chaiyakunapruk N

    更新日期：2018-04-24 00:00:00

  • Change in medical plant use in Estonian ethnomedicine: a historical comparison between 1888 and 1994.

    abstract：AIM OF THE STUDY:The aim of this paper is to compare the changes in the utilization of species from various hemeroby categories (indicating the degree of sensitivity of the plant to human impact) using historical data concerning the years 1888-1994. MATERIALS AND METHODS:The authors digitised 8808 handwritten reports,...

    journal_title：Journal of ethnopharmacology

    pub_type： 历史文章,杂志文章

    doi：10.1016/j.jep.2011.02.030

    authors： Sõukand R,Kalle R

    更新日期：2011-05-17 00:00:00

  • Amburana cearensis seed extract protects brain mitochondria from oxidative stress and cerebellar cells from excitotoxicity induced by glutamate.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Amburana cearensis (Allemao) A.C.Sm. is a medicinal plant of the Brazilian Caatinga reported to present antioxidant and anti-inflammatory activity. This study aimed to evaluate the neuroprotective effect of the extracts obtained from the seeds of A. cearensis in primary cultures of cerebe...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2017.07.017

    authors： Lima Pereira ÉP,Santos Souza C,Amparo J,Short Ferreira R,Nuñez-Figueredo Y,Gonzaga Fernandez L,Ribeiro PR,Braga-de-Souza S,Amaral da Silva VD,Lima Costa S

    更新日期：2017-09-14 00:00:00

  • Screening of New Caledonian and Vanuatu medicinal plants for antiprotozoal activity.

    abstract：:Sixty-seven extracts of 30 medicinal plants traditionally used in New Caledonia or Vanuatu by healers to treat inflammation, fever and in cicatrizing remedies were evaluated in vitro for their antiprotozoal activity against Leishmania donovani, Leishmania amazonensis and Trypanosoma cruzi. Among the selected plants, P...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2004.10.006

    authors： Billo M,Fournet A,Cabalion P,Waikedre J,Bories C,Loiseau P,Prina E,de Arias AR,Yaluff G,Fourneau C,Hocquemiller R

    更新日期：2005-01-15 00:00:00

  • Medicinal plants for gastrointestinal diseases among the Kuki-Chin ethnolinguistic groups across Bangladesh, India, and Myanmar: A comparative and network analysis study.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:The Kuki-Chin is a composite ethnolinguistic group made up of many distinct groups and subgroups that are linked by a common history, culture, and population distribution in the Kuki-Chin region, shared geopolitically by Bangladesh, India, and Myanmar. This region is shown to be in a hots...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jep.2019.112415

    authors： Ong HG,Kim YD

    更新日期：2020-04-06 00:00:00

  • Taoren-Honghua herb pair and its main components promoting blood circulation through influencing on hemorheology, plasma coagulation and platelet aggregation.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Persicae Semen (Taoren) and Carthami Flos (Honghua) used in pair which is named as Taoren-Honghua (TH) herb pair has been used in traditional Chinese medicine (TCM) for promoting blood circulation to dissipate blood stasis for many years in China. AIM OF THE STUDY:This paper investigated...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2011.11.016

    authors： Liu L,Duan JA,Tang Y,Guo J,Yang N,Ma H,Shi X

    更新日期：2012-01-31 00:00:00

  • Chemical profile- and pharmacokinetics-based investigation of the synergistic property of platycodonis radix in traditional Chinese medicine formula Shengxian decoction.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:To investigate the synergistic property of Platycodonis radix (PG) in a classic traditional Chinese medicine (TCM) prescription Shengxian decoction (SXT) by combining chemical profile with pharmacokinetic analysis strategy. The synergized prescription consisted of Astragali radix, Anemarr...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2014.01.033

    authors： Zhang F,Zhan Q,Gao S,Dong X,Jiang B,Sun L,Tao X,Chen WS

    更新日期：2014-03-28 00:00:00

  • A review on the elemental contents of Pakistani medicinal plants: Implications for folk medicines.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Substantially, plants produce chemicals such as primary and secondary metabolites, which have significant applications in modern therapy. Indigenous people mostly rely on traditional medicines derived from medicinal plants. These plants have the capacity to absorb a variety of toxic eleme...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jep.2016.05.011

    authors： Aziz MA,Adnan M,Begum S,Azizullah A,Nazir R,Iram S

    更新日期：2016-07-21 00:00:00

  • Xuefu Zhuyu decoction ameliorates obesity, hepatic steatosis, neuroinflammation, amyloid deposition and cognition impairment in metabolically stressed APPswe/PS1dE9 mice.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Metabolic syndrome and vascular dysfunction was suggested to be the risk factors for Alzheimer's disease (AD). Xuefu Zhuyu decoction (XZD) is a traditional Chinese medicine used to treat metabolic syndrome and cardiac-cerebral vascular disease. The effects of XZD on ameliorating metabolic...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2017.07.036

    authors： Yeh CW,Liu HK,Lin LC,Liou KT,Huang YC,Lin CH,Tzeng TT,Shie FS,Tsay HJ,Shiao YJ

    更新日期：2017-09-14 00:00:00

  • Various uses of the castor oil plant (Ricinus communis L.). A review.

    abstract：:The ancient and modern medicinal uses of the castor bean plant, Ricinus communis L. (Euphorbiaceae), in about fifty countries worldwide, has been surveyed. The different medicinal uses are grouped separately in relation to their pharmacological action, whether real or presumed, within the various medical specialties. ...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章,评审

    doi：10.1016/0378-8741(82)90038-1

    authors： Scarpa A,Guerci A

    更新日期：1982-03-01 00:00:00

  • 1H NMR-based metabolomics of antimalarial plant species traditionally used by Vha-Venda people in Limpopo Province, South Africa and isolation of antiplasmodial compounds.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:The Vha-Venda people living in rural areas of Limpopo Province of South Africa regularly use traditional plant-based medicines to treat malaria. In our earlier publication, twenty indigenous plant species used to treat malaria or its symptoms by Vha-Venda people were evaluated for antipla...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2018.07.022

    authors： Bapela MJ,Heyman H,Senejoux F,Meyer JJM

    更新日期：2019-01-10 00:00:00

  • Phytoestrogenic effect of Inula racemosa Hook f - A cardioprotective root drug in traditional medicine.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Roots of Inula racemosa are used as a cardio protective in Ayurveda in India, being prescribed as a medicine for precordial chest pain, cough and dyspnoea, both singly and as a poly herbal. AIM:Evaluation of Phytoestrogenic activity of the root extracts of Inula racemosa and compounds is...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2017.09.001

    authors： Kalachaveedu M,Raghavan D,Telapolu S,Kuruvilla S,Kedike B

    更新日期：2018-01-10 00:00:00

  • Oleanolic acid and ursolic acid: research perspectives.

    abstract：:Oleanolic acid and ursolic acid are ubiquitous triterpenoids in plant kingdom, medicinal herbs, and are integral part of the human diet. During the last decade over 700 research articles have been published on their research, reflecting tremendous interest and progress in our understanding of these triterpenoids. This...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jep.2005.05.024

    authors： Liu J

    更新日期：2005-08-22 00:00:00