Recent trends in research into African medicinal plants.

Abstract:

:Recent trends in research into African medicinal plants show that while ethnobotanical surveys continue, there is an appreciable increase in research activity in the area of bioactivity of natural products. The biological areas most researched include antimicrobial, molluscicidal, toxicity tests and antitumour in decreasing order. The isolation and characterisation of natural products from African plants without biological testing has yielded several compounds of novel structure and constitutes the majority of all the recent publications on African medicinal plants.

journal_name

J Ethnopharmacol

authors

Sofowora A

doi

10.1016/0378-8741(93)90017-y

subject

Has Abstract

pub_date

1993-03-01 00:00:00

pages

209-14

issue

2-3

eissn

0378-8741

issn

1872-7573

pii

0378-8741(93)90018-Z

journal_volume

38

pub_type

杂志文章,评审
  • In vitro cytotoxicity and immunomodulating property of Rhaphidophora korthalsii.

    abstract::An in vitro cytotoxic screening of extracts of Rhaphidophora korthalsii indicated cytotoxicity in the ether fraction. ED50 values of the extract against P388, Molt 4, KB and SW 620 were 12, 14, 8 and 13 micrograms/ml, respectively. The extract was relatively more toxic on P388 and Molt 4 cell lines at concentrations o...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/0378-8741(96)01391-8

    authors: Wong KT,Tan BK

    更新日期:1996-05-01 00:00:00

  • Effects of hydroethanolic extracts of Balanites aegyptiaca (L.) Delile (Balanitaceae) on some resistant pathogens bacteria isolated from wounds.

    abstract:BACKGROUND:The bark of Balanites aegyptiaca (L.) Delile (Balanitaceae) is widely used in the Togolese folk medicine for the treatment of wounds, malaria and skin diseases. This study aimed to evaluate the antioxidant properties and the activity of the bark extract of this plant against some resistant bacteria isolated ...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2015.01.051

    authors: Anani K,Adjrah Y,Ameyapoh Y,Karou SD,Agbonon A,de Souza C,Gbeassor M

    更新日期:2015-04-22 00:00:00

  • Analgesic and anti-inflammatory activities of ethanol root extract of Mahonia oiwakensis in mice.

    abstract:AIMS OF THE STUDY:This study investigated the anti-inflammatory and analgesic activities, and protoberberine alkaloid contents of ethanol extract of MO roots (MOR(EtOH)). MATERIALS AND METHODS:The analgesic activity of MOR(EtOH) was determined using acetic acid-induced writhing response and formalin test. The anti-inf...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2009.06.024

    authors: Chao J,Lu TC,Liao JW,Huang TH,Lee MS,Cheng HY,Ho LK,Kuo CL,Peng WH

    更新日期:2009-09-07 00:00:00

  • Inhibitory activity of Chrysanthemi sibirici herba extract on RBL-2H3 mast cells and compound 48/80-induced anaphylaxis.

    abstract::The effects of extracts from various oriental medicinal herbs on mast cell-mediated allergic reaction were investigated. Among them, Chrysanthemi sibirici herba ethanol extract exerted the potent inhibitory activity on antigen-induced degranulation in RBL-2H3 mast cells. Chrysanthemi sibirici herba dose-dependently in...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2004.08.023

    authors: Lee JH,Seo JY,Ko NY,Chang SH,Her E,Park T,Lee HY,Han JW,Kim YM,Choi WS

    更新日期:2004-12-01 00:00:00

  • The effect of Compound Danshen Dripping Pills, a Chinese herb medicine, on the pharmacokinetics and pharmacodynamics of warfarin in rats.

    abstract:AIM OF THE STUDY:Significant pharmacokinetic/pharmacodynamic (PK/PD) interactions between various herbal products and warfarin have recently been reported. The present study was conducted to determine whether Compound Danshen Dripping Pills (CDDP), a Chinese herb medicine used for the treatment of cardiovascular diseas...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2011.08.035

    authors: Chu Y,Zhang L,Wang XY,Guo JH,Guo ZX,Ma XH

    更新日期:2011-10-11 00:00:00

  • Modulation effect of Smilax glabra flavonoids on ryanodine receptor mediated intracellular Ca2+ release in cardiomyoblast cells.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Smilax glabra rhizome, a plant material from Liliaceae family, is a widely used traditional Chinese medicine for anti-cardiac hypertrophy treatment. We have previously found that Smilax glabra flavonoids (SGF) exerted such anti-cardiac hypertrophy activity. However, the mechanism of this ...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2013.08.009

    authors: Shou Q,Pan S,Tu J,Jiang J,Ling Y,Cai Y,Chen M,Wang D

    更新日期:2013-10-28 00:00:00

  • Hepatoprotective effect of total flavonoids of Mallotus apelta (Lour.) Muell.Arg. leaf against carbon tetrachloride-induced liver fibrosis in rats via modulation of TGF-β1/Smad and NF-κB signaling pathways.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:The Mallotus apelta (Lour.) Muell.Arg. is a well-known traditional Chinese medicine (TCM) used for anti-inflammatory, hemostasis and chronic hepatitis. AIM:The purpose of this study was to explore the antifibrotic effect of total flavonoids of Mallotus apelta leaf (TFM) and its potential...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2020.112714

    authors: Zhang B,Lai L,Tan Y,Liang Q,Bai F,Mai W,Huang Q,Ye Y

    更新日期:2020-05-23 00:00:00

  • Effect of a herbal protein, CI-1, isolated from Cajanus indicus on immune response of control and stressed mice.

    abstract::The effect of a herbal protein, CI-1, purified from the leaves of Cajanus indicus was evaluated as a probable immunomodulator on immune response in control and stressed mice. In mice, sensitized with sheep red blood cells (SRBC), CI-1 enhanced IgG level by 28% over control (P < 0.05). Primary and secondary antibody re...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/s0378-8741(99)00046-x

    authors: Datta S,Sinha S,Bhattacharyya P

    更新日期:1999-11-30 00:00:00

  • Effect of abana (a herbal preparation) on the radiation-induced mortality in mice.

    abstract::The effect of various doses (0, 5, 10, 20, 40 and 80 mg/kg body weight) of 50% ethanolic extract of abana, a traditional herbal preparation, widely used in India for the treatment of heart ailments, was studied on the radiation-induced mortality in mice exposed to 10 Gy of gamma-radiation. Treatment of mice with diffe...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/s0378-8741(03)00037-0

    authors: Jagetia GC,Baliga MS,Aruna R,Rajanikant GK,Jain V

    更新日期:2003-06-01 00:00:00

  • Protective Effects of Pistacia lentiscus L. fruit extract against calcium oxalate monohydrate induced proximal tubular injury.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:The world prevalence of kidney stones is increasing and plants are frequently used to treat urolithiasis. Pistacia lentiscus L, a plant which freely grows around the Mediterranean basin areas, is widely used for various pathologies. P. lentiscus has an important impact as it has economica...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2017.07.018

    authors: Cheraft-Bahloul N,Husson C,Ourtioualous M,Sinaeve S,Atmani D,Stévigny C,Nortier JL,Antoine MH

    更新日期:2017-09-14 00:00:00

  • Chemical profile- and pharmacokinetics-based investigation of the synergistic property of platycodonis radix in traditional Chinese medicine formula Shengxian decoction.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:To investigate the synergistic property of Platycodonis radix (PG) in a classic traditional Chinese medicine (TCM) prescription Shengxian decoction (SXT) by combining chemical profile with pharmacokinetic analysis strategy. The synergized prescription consisted of Astragali radix, Anemarr...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2014.01.033

    authors: Zhang F,Zhan Q,Gao S,Dong X,Jiang B,Sun L,Tao X,Chen WS

    更新日期:2014-03-28 00:00:00

  • Toxicological safety evaluation in acute and 28-day studies of aqueous extract from Serjania marginata Casar. (Sapindaceae) leaves in rats.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Serjania marginata Casar. (Sapindaceae) is a species traditionally known to be used for the treatment of gastric pain and inflammatory symptoms. AIM OF THIS STUDY:Due to the therapeutic importance of this species, this study investigated the toxicological effects of S. marginata leaves (...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2018.11.024

    authors: da Silva Moreira S,Tamashiro LK,Jorge BC,da Silva Balin P,Heredia-Vieira SC,de Almeida GL,Cardoso CAL,Kassuya CAL,Arena AC

    更新日期:2019-03-01 00:00:00

  • Cardiovascular responses in the normotensive rat produced by intravenous injection of gambirine isolated from Uncaria callophylla B1. ex Korth.

    abstract::Among several alkaloids, including dimeric indoles, isolated from Uncaria callophylla, gambirine which is an alkaloid unique to this plant, has been found to be another hypotensive principle from the plant. Intravenous injections of gambirine in the dose range of 0.2 to 10.0 mg/kg caused a dose-related fall in both sy...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/0378-8741(92)90047-u

    authors: Mok JS,Chang P,Lee KH,Kam TS,Goh SH

    更新日期:1992-06-01 00:00:00

  • QingYan formula extracts protect against postmenopausal osteoporosis in ovariectomized rat model via active ER-dependent MEK/ERK and PI3K/Akt signal pathways.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:QingYan Formula has been traditionally used to tonify kidney and benefit essence, and QingYan Formula 70% ethanol extracts (QYFE) showed estrogen-like effect on reproductive system in our previous studies. However, there were no reports of QYFE on bone. AIM OF THE STUDY:This study offere...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2020.113644

    authors: Zhao Y,Xu Y,Zheng H,Lin N

    更新日期:2021-03-25 00:00:00

  • Bioassay-guided isolation and evaluation of anti-osteoporotic polysaccharides from Morinda officinalis.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Morinda officinalis is a well-known Chinese tonic herb that has shown clinical efficacy in the treatment of bone disease. However, its anti-osteoporotic potential and the M. officinalis polysaccharides (MOPs) responsible for activity require further investigation. AIM OF THE STUDY:This s...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2020.113113

    authors: Zhang D,Zhang S,Jiang K,Li T,Yan C

    更新日期:2020-10-28 00:00:00

  • Bu-Shen-Fang-Chuan formula attenuates cigarette smoke-induced inflammation by modulating the PI3K/Akt-Nrf2 and NF-κB signalling pathways.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Chronic obstructive pulmonary disease (COPD) is a respiratory inflammatory disease. Unlike asthma, COPD is insensitive to glucocorticoid treatment; thus, it is of great importance to find alternative medications, including Chinese medicine, to suppress inflammation. Bu-Shen-Fang-Chuan for...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2020.113095

    authors: Li Q,Wang G,Xiong SH,Cao Y,Liu B,Sun J,Li L,Mohammadtursun N,Yu H,Dong J,Wu J

    更新日期:2020-10-28 00:00:00

  • The optimal dose of arsenic trioxide induced opposite efficacy in autophagy between K562 cells and their initiating cells to eradicate human myelogenous leukemia.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Arsenic trioxide (As2O3), a main component of arsenolite which is a common traditional Chinese medicine (TCM) wildly used as a therapeutic agent for more than 2400 years in china, has been accepted as a standard treatment for the patients with acute promyelocytic leukemia (APL) based on t...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2016.12.010

    authors: Guo Z,Meng M,Geng S,Du Z,Zheng Y,Yao J,Li Z,Han G,Lin H,Du G

    更新日期:2017-01-20 00:00:00

  • Fasciolicidal efficacy of Albizia anthelmintica and Balanites aegyptiaca compared with albendazole.

    abstract::An attempt was made to evaluate the oral doses of 9 g/kg-body weight of Albizzia anthelmintica Brong. Mimoaseae stem bark water extract and 9 g/kg body weight of B. aegyptiaca (L) Del. (Balanitaceae) fruit mesocarp water extract (traditionally used as an anthelmintic in the Sudan) compared with 20 mg/kg body weight (r...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/s0378-8741(00)00172-0

    authors: Koko WS,Galal M,Khalid HS

    更新日期:2000-07-01 00:00:00

  • Aphrodisiac properties of Allium tuberosum seeds extract.

    abstract:AIM OF THE STUDY:In the present study, we examined the effect of Allium tuberosum seeds extract upon the expression of male rat sexual behavior, in order to know whether Allium tuberosum seeds extract possess aphrodisiac property. MATERIALS AND METHODS:The aphrodisiac activity of Allium tuberosum seeds n-BuOH extract ...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2009.01.018

    authors: Guohua H,Yanhua L,Rengang M,Dongzhi W,Zhengzhi M,Hua Z

    更新日期:2009-04-21 00:00:00

  • The polyherbal drug GGEx18 from Laminaria japonica, Rheum palmatum, and Ephedra sinica inhibits hepatic steatosis and fibroinflammtion in high-fat diet-induced obese mice.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:The herbal composition Gyeongshingangjeehwan 18 (GGEx18), composed of Rheum palmatum L. (Polygonaceae), Laminaria japonica Aresch (Laminariaceae), and Ephedra sinica Stapf (Ephedraceae), is used as an antiobesity drug in Korean clinics. The constituents of GGEx18 have traditionally been r...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2018.06.034

    authors: Lim J,Lee H,Ahn J,Kim J,Jang J,Park Y,Jeong B,Yang H,Shin SS,Yoon M

    更新日期:2018-10-28 00:00:00

  • Evaluation of the toxicity of Solanum lycocarpum in the reproductive system of male mice and rats.

    abstract::Powdered Solanum lycocarpum fruit is commonly used to treat diabetes, but apparently no studies have been conducted to evaluate potential adverse side effects. In the present paper the toxic effect of S. lycocarpum was evaluated in adult male Wistar rats and Swiss mice. The administration of an aqueous extract prepare...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/s0378-8741(00)00250-6

    authors: de Cássia da SeSá R,Vireque AA,Reis JE,Guerra MO

    更新日期:2000-11-01 00:00:00

  • Pallidifloside D, a saponin glycoside constituent from Smilax riparia, resist to hyperuricemia based on URAT1 and GLUT9 in hyperuricemic mice.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:The roots and rhizomes of Smilax riparia (SR), called "Niu-Wei-Cai" in traditional Chinese medicine (TCM), are believed to be effective in treating hyperuricemia and gout symptoms. This study was designed to isolate a saponin glycoside named pallidifloside D from the total saponins of Smi...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2014.09.034

    authors: Wu XH,Ruan JL,Zhang J,Wang SQ,Zhang YW

    更新日期:2014-11-18 00:00:00

  • The antimicrobial activity of 3,5,7-trihydroxyflavone isolated from the shoots of Helichrysum aureonitens.

    abstract::Extracts from Helichrysum aureonitens are used topically by the indigenous people of South Africa against infections. The antimicrobial activity-guided fractionation by bioautography of the acetone extract from the aerial parts of H. aureonitens led to the isolation of 3,5,7-trihydroxyflavone (galangin). Evaluation of...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/s0378-8741(97)00065-2

    authors: Afolayan AJ,Meyer JJ

    更新日期:1997-08-01 00:00:00

  • Antidepressant-like effect of ethanol extract from Zuojin Pill, containing two herbal drugs of Rhizoma Coptidis and Fructus Evodiae, is explained by modulating the monoaminergic neurotransmitter system in mice.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Zuojin Pill (ZJP), a traditional Chinese medicinal decoction, contains two herbal drugs: Coptis chinensis Franch. and Evodia rutaecarpa (Juss.) Benth. in the ratio of 6:1 (w/w). Previous pharmacological studies have shown that two herbs in ZJP have the antagonistic effects on catecholamin...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2013.05.011

    authors: Wang QS,Ding SL,Mao HP,Cui YL,Qi XJ

    更新日期:2013-07-09 00:00:00

  • Preventive effect of traditional herbal formulae against experimental hypercholesterolemia in rats with special reference to blood lipoprotein cholesterol levels.

    abstract::To investigate the effect of traditional herbal formulae (Zhong Yao) against experimental hypercholesterolemia, we assayed serum lipoprotein levels and hepatic function in rats administered herbal formulae under cholesterol rich diet. Two kinds of herbal formulae; prescription 1 (Bupleurum chinense and other 9 kinds o...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2004.05.009

    authors: Cheng BJ,Moritomo A,Yamasaki Y,Wu LX,Inagaki M,Nishimura M,Tanishima K,Poracova J

    更新日期:2004-10-01 00:00:00

  • Immunostimulant activity of dry fruits and plant materials used in indian traditional medical system for mothers after child birth and invalids.

    abstract::Products of certain plants given to mothers after child birth or to invalids were studied for immunostimulant activity using the macrophage migration index (MMI) as a parameter of macrophage activation and cell-mediated immunity and haemagglutinating antibody (HA) titres and plaque-forming cell (PFC) counts as paramet...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/s0378-8741(99)00181-6

    authors: Puri A,Sahai R,Singh KL,Saxena RP,Tandon JS,Saxena KC

    更新日期:2000-07-01 00:00:00

  • Antimalarial activity of cedronin.

    abstract::Cedronin was isolated from Simaba cedron Planchon (Simaroubaceae), a species popularly believed in South America to have antimalarial properties. It was examined for in vitro and in vivo antimalarial activities and for cytotoxicity against KB cells. Experimental results showed that cedronin was active against chloroqu...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/0378-8741(94)90117-1

    authors: Moretti C,Deharo E,Sauvain M,Jardel C,David PT,Gasquet M

    更新日期:1994-06-01 00:00:00

  • Boldine action against the stannous chloride effect.

    abstract::Peumus boldus extract has been used in popular medicine in the treatment of biliar litiase, hepatic insufficiency and liver congestion. Its effects are associated to the substance boldine that is present in its extract. In the present work, we evaluated the influence of boldine both in: (i) the structural conformation...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/s0378-8741(99)00120-8

    authors: Reiniger IW,Ribeiro da Silva C,Felzenszwalb I,de Mattos JC,de Oliveira JF,da Silva Dantas FJ,Bezerra RJ,Caldeira-de-Araújo A,Bernardo-Filho M

    更新日期:1999-12-15 00:00:00

  • Treatment of osteoarthritis with a herbomineral formulation: a double-blind, placebo-controlled, cross-over study.

    abstract::The clinical efficacy of a herbomineral formulation containing roots of Withania somnifera, the stem of Boswellia serrata, rhizomes of Curcuma longa and a zinc complex (Articulin-F), was evaluated in a randomized, double-blind, placebo controlled, cross-over study in patients with osteoarthritis. After a one-month sin...

    journal_title:Journal of ethnopharmacology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/0378-8741(91)90167-c

    authors: Kulkarni RR,Patki PS,Jog VP,Gandage SG,Patwardhan B

    更新日期:1991-05-01 00:00:00

  • Chemical composition, antioxidant and anti-inflammatory activities of the essential oils from male and female specimens of Baccharis punctulata (Asteraceae).

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Baccharis punctulata (Asteraceae), popularly known as "Chíllka saru saru" in Bolivia, has been used by rural communities in Bustillo Province of the Potosi Department for treatment of asthma, luxations and contusions. AIM OF THE STUDY:To analyze the chemical composition of the essential ...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2019.01.005

    authors: Ascari J,de Oliveira MS,Nunes DS,Granato D,Scharf DR,Simionatto E,Otuki M,Soley B,Heiden G

    更新日期:2019-04-24 00:00:00