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Screening of New Caledonian and Vanuatu medicinal plants for antiprotozoal activity.

Abstract：

:Sixty-seven extracts of 30 medicinal plants traditionally used in New Caledonia or Vanuatu by healers to treat inflammation, fever and in cicatrizing remedies were evaluated in vitro for their antiprotozoal activity against Leishmania donovani, Leishmania amazonensis and Trypanosoma cruzi. Among the selected plants, Pagiantha cerifera was the most active against both Leishmania species; four extracts were active against promastigotes of Leishmania donovani at EC(50) values inferior to 5 microg/ml. Garcinia pedicillata extract had an EC(50) value of 12.5 microg/ml against intracellular amastigotes of Leishmania amazonensis. Alone Amborella trichopoda reduced by more of 80% the trypomastigotes of Trypanosoma cruzi in the blood.

journal_name

J Ethnopharmacol

journal_title

Journal of ethnopharmacology

authors

Billo M,Fournet A,Cabalion P,Waikedre J,Bories C,Loiseau P,Prina E,de Arias AR,Yaluff G,Fourneau C,Hocquemiller R

doi

10.1016/j.jep.2004.10.006

keywords:

subject

Has Abstract

pub_date

2005-01-15 00:00:00

pages

569-75

issue

3

eissn

0378-8741

issn

1872-7573

pii

S0378-8741(04)00507-0

journal_volume

96

pub_type

杂志文章

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