Studies on antimycotic properties of Datura metel.


:The hexane, chloroform, acetone and methanolic fractions of Datura metel L. were investigated for antifungal properties using pathogenic species of Aspergillus. The chloroform fraction was found to be endowed with antifungal activity. The minimum inhibitory concentration (MIC) of chloroform fraction of D. metel L. was 625.0 microg ml(-1) against all the three species of Aspergillus, i.e. A. fumigatus, A. flavus and A. niger, by microbroth dilution and percent spore germination inhibition assays. The MIC by disc diffusion assay was observed to be 12.5 microg disc(-1). The chloroform fraction of D. metel, when investigated for potency, turned to be 9.2 times less active than amphotericin B. However, it was important to note that the cytotoxicity of chloroform fraction in vitro was 117.8 times less than amphotericin B.


J Ethnopharmacol


Rajesh,Sharma GL





Has Abstract


2002-05-01 00:00:00














  • Medicinal plants of Seberida (Riau Province, Sumatra, Indonesia).

    abstract::Field enquiries on the plants used to treat diseases in villages of Seberida Municipality indicated that a large number of plant species (at least 100) are being used in therapy. Many of the uses, however, are magical in nature. Those in which a cause-effect relationship may be established (56) are presented in this p...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章,评审


    authors: Mahyar UW,Burley JS,Gyllenhaal C,Soejarto DD

    更新日期:1991-02-01 00:00:00

  • Beneficial effects of Chinese prescription Kangen-karyu on diabetes associated with hyperlipidemia, advanced glycation endproducts, and oxidative stress in streptozotocin-induced diabetic rats.

    abstract:AIM OF THE STUDY:In the present study, we investigated the effects of Kangen-karyu, a traditional Chinese prescription comprising six herbs, on diabetes. MATERIALS AND METHODS:Kangen-karyu extract (50, 100, or 200mg/kg body weight) was administered to streptozotocin (STZ)-induced diabetic rats and serum and hepatic bi...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Kim HY,Okamoto T,Yokozawa T

    更新日期:2009-07-15 00:00:00

  • Isolation and characterization of antimicrobial compounds from Terminalia phanerophlebia Engl. & Diels leaf extracts.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:The emergence of drug resistant-tuberculosis and other pathogenic diseases over the past decades, constitutes a serious threat to human health worldwide. According to a 2012 report by the World Health Organization (WHO), South Africa, China, India and Russia are the countries with the hig...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Madikizela B,Aderogba MA,Finnie JF,Van Staden J

    更新日期:2014-10-28 00:00:00

  • Anti-anxiety effects of Apocynum venetum L. in the elevated plus maze test.

    abstract::The purpose of this study was to characterize the putative anxiolytic-like activity of an ethanolic extract prepared from the leaves of Apocynum venetum (AV) using the elevated plus maze (EPM) in mice. Male C75BL/6 mice were either treated orally with the AV extract or the positive controls diazepam and buspirone, res...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Grundmann O,Nakajima J,Seo S,Butterweck V

    更新日期:2007-04-04 00:00:00

  • Hallucinogenic plant use and related indigenous belief systems in the Ecuadorian Amazon.

    abstract::This review article focuses on the on-going use of plant hallucinogens, especially various Banisteriopsis species, among contemporary aboriginal populations of Ecuador. It surveys the evidence of prehistoric ayahuasca use by interpretations of Ecuadorian archaeological remains, and surveys in detail the use and belief...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Naranjo P

    更新日期:1979-04-01 00:00:00

  • Traditional uses of some medicinal plants in Malatya (Turkey).

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:This study has identified not only the wild plants collected for medical purposes by local people of Malatya Province in the Eastern Anatolia Region, but also the uses and local names of these plants. It tried to provide a source for researchers studying in ethnobotany, pharmacology and c...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Tetik F,Civelek S,Cakilcioglu U

    更新日期:2013-03-07 00:00:00

  • Chemical composition and evaluation of antioxidant activities, antimicrobial, and anti-melanogenesis effect of the essential oils extracted from Dalbergia pinnata (Lour.) Prain.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Dalbergia pinnata (Lour.) Prain (D. pinnata) is a plant widely distributed in tropical and subtropical regions of Asia, Africa, and the Americas. In humans, it is used in the prevention and treatment of diseases such as respiratory system, digestive system, cardiovascular and cerebrovascu...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Zhou W,He Y,Lei X,Liao L,Fu T,Yuan Y,Huang X,Zou L,Liu Y,Ruan R,Li J

    更新日期:2020-05-23 00:00:00

  • Protective role of Anacardium occidentale extract against streptozotocin-induced diabetes in rats.

    abstract::The protective effect of Anacardium occidentale aqueous extract against streptozotocin-induced diabetes was evaluated in rats. The rats were treated with 175 mg/kg of the extract per os, twice daily; beginning 2 days before streptozotocin (STZ) injection. A total of 3 days after STZ administration, there was a 48% inc...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Kamtchouing P,Sokeng SD,Moundipa PF,Watcho P,Jatsa HB,Lontsi D

    更新日期:1998-09-01 00:00:00

  • Therapeutic effect of Dongbai-Tonglin-Fang, a Chinese herbal formula, on urinary tract infection in rat model.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Traditional Chinese Medicine (TCM) has many obvious advantages in the treatment of chronic conditions such as urinary tract infection (UTI). Dongbai-Tonglin-Fang (DBTL), a Chinese herbal formula, has been used for the treatment of UTI for more than 40 years with proven efficacy. However, ...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Li XQ,Zhu JY,Pan RR,Shen YL,Rahman K,Zhang CY,Zhang LJ,Luan X,Zhang H

    更新日期:2019-09-15 00:00:00

  • Management of diabetic complications: a chemical constituents based approach.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Long term hyperglycemia leads to development of complications associated with diabetes. Diabetic complications are now a global health problem without effective therapeutic approach. Hyperglycemia and oxidative stress are important components for the development of diabetic complications....

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章,评审


    authors: Singh R,Kaur N,Kishore L,Gupta GK

    更新日期:2013-10-28 00:00:00

  • Inhibitory effects of Saussurea involucrata (Kar. et Kir.) Sch. -Bip. on adjuvant arthritis in rats.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Saussurea involucrate (Kar. et Kir.) Sch. -Bip is an endangered species of the Compositae family, and this species has long been used for the treatment of rheumatoid arthritis, dysmenorrhea, stomachache, and altitude sickness in Uighur folk and Chinese medicine. AIM OF THE STUDY:This stu...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Han X,Su D,Xian X,Zhou M,Li X,Huang J,Wang J,Gao H

    更新日期:2016-12-24 00:00:00

  • Pharmacologic effects of an aqueous extract of Rhigiocarya racemifera.

    abstract::Several pharmacologic studies were carried out with an aqueous extract of Rhigiocarya racemifera after phytochemical tests revealed the main constituents to be glycosides, saponins and tannins. Studies on intact mice showed that the extract has an intraperitoneal LD50 of 142 mg/kg and that 50 mg/kg of the extract redu...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Aguwa CN

    更新日期:1986-02-01 00:00:00

  • Mechanisms of anti-inflammatory effect of an active ingredients group from Jinxuan Zhike Xunxi San.

    abstract:AIM OF THE STUDY:JZXS has been used for inflamed hemorrhoids as a chinese prescription for several decades. The present study was designed to investigate the anti-inflammatory activities, as well as the mechanisms, of an active ingredients group (AIG) obtained from Jinxuan Zhike Xunxi San (JZXS). MATERIALS AND METHODS...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Wen L,Zhou L,Liu W,Huang H,Li Y,Wang H,Zhang W,Liu Y

    更新日期:2011-05-17 00:00:00

  • Ethanol extraction preparation of American ginseng (Panax quinquefolius L) and Korean red ginseng (Panax ginseng C.A. Meyer): differential effects on postprandial insulinemia in healthy individuals.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Ginsenosides are the proposed bioactive constituent of ginseng, especially for the attenuation of postprandial glycemia (PPG). The efficacious proportion of total and specific ginsenosides, remains unknown. Alcohol extraction of whole ginseng root can be used to selectively manipulate the...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章,随机对照试验


    authors: De Souza LR,Jenkins AL,Jovanovski E,Rahelić D,Vuksan V

    更新日期:2015-01-15 00:00:00

  • Effect of saponins from Helicteres isora on lipid and glucose metabolism regulating genes expression.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:We characterized saponins as active constituents from traditionally used antidiabetic plant Helicteres isora. AIM OF THE STUDY:To evaluate the changes in the gene expression of the glucose and lipid metabolism regulating genes in C57BL/KsJ-db/db mice. MATERIALS AND METHODS:C57BL/KsJ-db/...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Bhavsar SK,Singh S,Giri S,Jain MR,Santani DD

    更新日期:2009-07-30 00:00:00

  • Antibacterial and antibiotic modifying activity evaluation of ruminants' body fat used as zootherapeutics in ethnoveterinary practices in Northeast Brazil.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Northeast Brazilian ethnoveterinary studies associated with the medicinal use of zootherapies have shown that ruminants' body fat such as sheep (Ovis aries), goats (Capra hircus) and cows (Bos taurus) are used in diseases affecting domestic animals. AIM OF THE STUDY:The objective of this...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: de Queiroz Dias D,Sales DL,Andrade JC,da Silva ARP,Tintino SR,Oliveira-Tintino CDM,de Araújo Delmondes G,de Oliveira Barbosa M,Coutinho HDM,Ferreira FS,Rocha MFG,Navarro DMDAF,da Rocha SKL,da Costa JGM,Alves RRDN,Almeida WO

    更新日期:2019-04-06 00:00:00

  • Antiquity of medicinal plant usage in two Macro-Mayan ethnic groups (México).

    abstract::In the biological sciences the use of medicinal plants in indigenous cultures is commonly seen as being based on a long tradition ('traditional medicine'). However, under normal circumstances, ethnobotanical studies cannot provide evidence on the antiquity of specific uses for medicinal plants since oral traditions ha...

    journal_title:Journal of ethnopharmacology

    pub_type: 历史文章,杂志文章


    authors: Leonti M,Sticher O,Heinrich M

    更新日期:2003-10-01 00:00:00

  • Osteoprotective effect of extract from Achyranthes bidentata in ovariectomized rats.

    abstract:AIM OF THE STUDY:A Chinese herbal drug, root of Achyranthes bidentata showed a potent inhibitory activity on bone resorption induced by parathyroid hormone (PTH) in a bone organ culture using neonatal mouse parietal bones. The present study is to clarify the fractions responsible for the activity and further explore th...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: He CC,Hui RR,Tezuka Y,Kadota S,Li JX

    更新日期:2010-02-03 00:00:00

  • Can the aggregation be a new approach for understanding the mechanism of Traditional Chinese Medicine?

    abstract::"Frequent hitter" phenomenon emerged in the high-throughput screening; one of the most common mechanisms behind artifactual inhibition is that some organic molecules formed large colloid-like aggregates which are able to sequester and thereby inhibit enzymes. To investigate the situation in Traditional Chinese Medicin...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Zhuang Y,Yan J,Zhu W,Chen L,Liang D,Xu X

    更新日期:2008-05-08 00:00:00

  • A complex prescription for vitiligo activates mitochondrial ATP synthase-6 expression in B-16 murine melanoma cells.

    abstract::A complex prescription (CP) used traditionally for the treatment of vitiligo was prepared from water extract of eight plant materials. To study the mechanism of this preparation its effect on gene expression of B-16 murine melanoma cells was estimated using differential display method (DDRT-PCR). The results showed th...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Li W,Yu W,Dong Q,Wang P,Chen Q

    更新日期:2004-06-01 00:00:00

  • Regulation effects on abnormal glucose and lipid metabolism of TZQ-F, a new kind of Traditional Chinese Medicine.

    abstract:AIM OF THE STUDY:Based on the recipe of the traditional anti-diabetic formula TZQ, we developed TZQ-F, a new formula including 8 fractions isolated from Red Paeony root, Mulberry leaf, Lotus leaf, Danshen root and Hawthorn leaf with a good quality assurance. The study was aimed at fraction preparation and effects of th...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Tao W,Deqin Z,Yuhong L,Hong L,Zhanbiao L,Chunfeng Z,Limin H,Xiumei G

    更新日期:2010-04-21 00:00:00

  • Anti-bone resorption activity of deer antler aqua-acupunture, the pilose antler of Cervus korean TEMMINCK var. mantchuricus Swinhoe (Nokyong) in adjuvant-induced arthritic rats.

    abstract::Effect of deer antler aqua-acupunture (DAA), prepared from the pilose antler of Cervus korean TEMMINCK var. mantchuricus Swinhoe, a traditional immunosuppressive acupuncture, was evaluated to assess the reductions in bone mass, strength, and turnover in adjuvant-induced arthritic rats. For measuring the above paramete...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Kim KH,Kim KS,Choi BJ,Chung KH,Chang YC,Lee SD,Park KK,Kim HM,Kim CH

    更新日期:2005-01-15 00:00:00

  • In vitro cytotoxicity and immunomodulating property of Rhaphidophora korthalsii.

    abstract::An in vitro cytotoxic screening of extracts of Rhaphidophora korthalsii indicated cytotoxicity in the ether fraction. ED50 values of the extract against P388, Molt 4, KB and SW 620 were 12, 14, 8 and 13 micrograms/ml, respectively. The extract was relatively more toxic on P388 and Molt 4 cell lines at concentrations o...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Wong KT,Tan BK

    更新日期:1996-05-01 00:00:00

  • The suppressive effects of Saposhnikovia divaricata (Fangfeng) chromone extract on rheumatoid arthritis via inhibition of nuclear factor-κB and mitogen activated proteinkinases activation on collagen-induced arthritis model.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Saposhnikovia divaricata (SD), called "Fangfeng" in China, is commonly used in clinical compound prescription for treatment of rheumatoid arthritis (RA), but its actions on RA have not been clarified. The present study aims to determine the anti-inflammatory activity of SD chromone extrac...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Kong X,Liu C,Zhang C,Zhao J,Wang J,Wan H,Zhu H,Zhang P,Chen W,Xiao Y,Lin N

    更新日期:2013-07-30 00:00:00

  • The adjuvant effects of Antrodia Camphorata extracts combined with anti-tumor agents on multidrug resistant human hepatoma cells.

    abstract:AIM OF THE STUDY:The objectives of this study were to investigate the adjuvant anti-tumor effects of Antrodia camphorate in human hepatoma cells (C3A and PLC/PRF/5) which are resistance to most anti-tumor agents, elucidate the possible regulation pathways, and measure the tumor growth and survival rate in xenograft-nud...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Chang CY,Huang ZN,Yu HH,Chang LH,Li SL,Chen YP,Lee KY,Chuu JJ

    更新日期:2008-08-13 00:00:00

  • The methanolic extract of Boesenbergia rotunda (L.) Mansf. and its major compound pinostrobin induces anti-ulcerogenic property in vivo: possible involvement of indirect antioxidant action.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Boesenbergia rotunda (L) Mansf. has been used for the treatment of gastrointestinal disorders including peptic ulcer. In the current study we aimed to investiagte the anti-ulcer activities of methanolic extract of B. rotunda (MEBR) and its main active compound, pinostrobin on ethanol-indu...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Abdelwahab SI,Mohan S,Abdulla MA,Sukari MA,Abdul AB,Taha MM,Syam S,Ahmad S,Lee KH

    更新日期:2011-09-02 00:00:00

  • Medicinal plants of the Popoluca, México: organoleptic properties as indigenous selection criteria.

    abstract::The taste and smell of the environment are important to humans in everyday life and are of particular relevance for the selection of medicinal versus non-medicinal plant species. In a 16-months study with the Popoluca of southern Veracruz (Mexico), we focused on the indigenous selection criteria for medicinal plants. ...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Leonti M,Sticher O,Heinrich M

    更新日期:2002-08-01 00:00:00

  • Treatment with Azadirachta indica in diabetic pregnant rats: negative effects on maternal outcome.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:The role of Azadirachta indica (neem) against Chagas disease and its antibiotic and antidiabetic action have been demonstrated in non-pregnant animals. However, the effects of neem on lipid metabolism and oxidative stress during pregnancy remain to be investigated. The objective of this s...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Dallaqua B,Saito FH,Rodrigues T,Calderon IM,Rudge MV,Herrera E,Damasceno DC

    更新日期:2012-10-11 00:00:00

  • Toxicology, genotoxicity, and cytotoxicity of three extracts of Solanum chrysotrichum.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Infusions of Solanum chrysotrichum (Schldl.) or "sosa" are employed in Traditional Mexican Medicine for the local and systemic treatment of skin and mucosal infections. Different studies have verified its antifungal effectiveness and therapeutic safety in superficial mycosis caused by der...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Aguilar-Santamaría L,Herrera-Arellano A,Zamilpa A,Alonso-Cortés D,Jiménez-Ferrer E,Tortoriello J,Zúñiga-González G

    更新日期:2013-10-28 00:00:00

  • In vitro and in vivo anti-inflammatory effects of an ethanol extract from the aerial parts of Eryngium carlinae F. Delaroche (Apiaceae).

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Eryngium carlinae F. Delaroche (Apiaceae) is an herb used in folk medicine as a diuretic, analgesic, and anti-inflammatory agent. AIM OF THE STUDY:This work assessed the diuretic, antinociceptive, and anti-inflammatory actions of an ethanol extract from the leaves and stems of Eryngium c...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Arana-Argáez V,Alonso-Castro AJ,Yáñez-Barrientos E,Euan-Canto A,Torres-Romero JC,Isiordia-Espinoza MA,Brennan-Bourdon LM,Juárez-Vázquez MDC,González-Ibarra AA

    更新日期:2021-02-10 00:00:00