当前位置： SCI文献检索 > JOURNAL OF ETHNOPHARMACOLOGY期刊下所有文献 > Bromelain, the enzyme complex of pineapple (Ananas comosus) and its clinical application. An update.

Bromelain, the enzyme complex of pineapple (Ananas comosus) and its clinical application. An update.

Abstract：

:After a short description of the uses of pineapple as folk medicine by the natives of the tropics, the more important new pharmaceutical applications of bromelain, reported between 1975 and 1978, are presented. Although the exact chemical structure of all active components of bromelain is not fully determined, this substance has shown distinct pharmacological promise. Its properties include: (1) interference with growth of malignant cells; (2) inhibition of platelet aggregation; (3) fibrinolytic activity; (4) anti-inflammatory action; (5) skin debridement properties. These biological functions of bromelain, a non-toxic compound, have therapeutic values in modulating: (a) tumor growth; (b) blood coagulation; (c) inflammatory changes; (d) debridement of third degree burns; (e) enhancement of absorption of drugs. The mechanism of action of bromelain affecting these varied biological effects relates in part to its modulation of the arachidonate cascade.

journal_name

J Ethnopharmacol

journal_title

Journal of ethnopharmacology

authors

Taussig SJ,Batkin S

doi

10.1016/0378-8741(88)90127-4

subject

Has Abstract

pub_date

1988-02-01 00:00:00

pages

191-203

issue

2

eissn

0378-8741

issn

1872-7573

pii

0378-8741(88)90127-4

journal_volume

22

pub_type

杂志文章,评审

相关文献

JOURNAL OF ETHNOPHARMACOLOGY文献大全
  • In vitro evidence of phyto-synergy for plant part combinations of Croton gratissimus (Euphorbiaceae) used in African traditional healing.

    abstract：AIM OF THE STUDY:Despite the extensive traditional use of Croton gratissimus Burch. var. gratissimus for medicinal purposes, scientific studies validating the therapeutic properties of this indigenous plant are lacking. As the bark, roots and leaves of C. gratissimus are used separately as well as in combination, this ...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2008.06.031

    authors： van Vuuren SF,Viljoen AM

    更新日期：2008-10-28 00:00:00

  • Activity of medicinal plants from Ghana against the parasitic gut protist Blastocystis.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:The plants tested in this study were examples of plants historically used to treat or alleviate several types of stomach disorders manifested by e.g. stomachache, diarrhoea or dysentery. These plants have been consumed typically as a decoction, sometimes mixed with other flavourings. The ...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2015.03.006

    authors： Bremer Christensen C,Soelberg J,Stensvold CR,Jäger AK

    更新日期：2015-11-04 00:00:00

  • Pharmacological basis for use of Lychnophora trichocarpha in gouty arthritis: anti-hyperuricemic and anti-inflammatory effects of its extract, fraction and constituents.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:The ethanolic extract of Lychnophora trichocarpha Spreng. is used in Brazilian folk medicine to treat bruise, pain and inflammatory diseases. AIM OF THE STUDY:The present study aimed at investigating whether ethanolic extract of L. trichocarpha, its ethyl acetate fraction and its main bi...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2012.06.012

    authors： de Souza MR,de Paula CA,Pereira de Resende ML,Grabe-Guimarães A,de Souza Filho JD,Saúde-Guimarães DA

    更新日期：2012-08-01 00:00:00

  • Evaluation of extracts of Anthocleista djalonensis, Nauclea latifolia and Uvaria afzalii for activity against bacterial isolates from cases of non-gonococcal urethritis.

    abstract：:Whole root preparations of three Nigerian medicinal plants, Anthocleista djalonensis, Nauclea latifolia and Uvaria afzalii, used traditionally in combination treatment of sexually transmitted diseases (STD), were extracted by maceration in ethanol, cold and hot water, respectively. The extracts were tested, by agar di...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2003.12.015

    authors： Okoli AS,Iroegbu CU

    更新日期：2004-05-01 00:00:00

  • Antimicrobial, antioxidant and cytotoxic properties of essential oil from Dictamnus angustifolius.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Dictamnus angustifolius (Rutaceae) has been used as an alternative for folk medicine, Dictamnus dasycarpus in the treatment of rheumatism, bleeding, itching, jaundice, chronic hepatitis, and skin diseases in Xinjiang Province of China. The aim of this study was to evaluate the antimicrobi...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2014.06.055

    authors： Sun J,Wang X,Wang P,Li L,Qu W,Liang J

    更新日期：2015-01-15 00:00:00

  • Possible involvement of amine oxidase inhibition in the sympathetic activation induced by khat (Catha edulis) chewing in humans.

    abstract：:The possibility that phenylalkylamines (cathinone and cathine) of khat, like amphetamines, are amine oxidase inhibitors with clinical significance is evaluated. Results show that khat chewing induces a significant increase in blood pressure, body temperature and urinary catecholamines in khat naive subjects. On the ot...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/0378-8741(84)90097-7

    authors： Nencini P,Amiconi G,Befani O,Abdullahi MA,Anania MC

    更新日期：1984-06-01 00:00:00

  • Nitrite oxide and inducible nitric oxide synthase were regulated by polysaccharides isolated from Glycyrrhiza uralensis Fisch.

    abstract：:Water-soluble polysaccharide(Glycyrrhiza polysaccharide, GP) was isolated from Glycyrrhiza uralensis Fisch, with glycosidic units were composed of alpha (1-4) linked D-glucana. We demonstrated that GP significantly induces nitric oxides (NO) production and inducible NO synthase (iNOS) transcription in peritoneal macro...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2008.03.002

    authors： Cheng A,Wan F,Jin Z,Wang J,Xu X

    更新日期：2008-06-19 00:00:00

  • Antidiabetic activity and toxicity of Zizyphus spina-christi leaves.

    abstract：:The effect of the butanol extract of Zizyphus spina-christi (L.), Willd (Rhamnaceae) leaves and its major saponin glycoside, christinin-A, on the serum glucose and insulin levels was studied in non-diabetic control, type-I (insulin-dependent) and type-II (non-insulin-dependent) diabetic rats. Pretreatment either with ...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2005.04.007

    authors： Abdel-Zaher AO,Salim SY,Assaf MH,Abdel-Hady RH

    更新日期：2005-10-03 00:00:00

  • Inhibitory effects of the root cortex of Paeonia suffruticosa on interleukin-8 and macrophage chemoattractant protein-1 secretions in U937 cells.

    abstract：:In an effort to elucidate the mechanism of the anti-inflammatory effect of mudanpi, the root cortex of Paeonia suffruticosa Andrews (Ranunculaceae), we determined the effects of the methanolic extract of mudanpi (MEM) on the secretions of interleukin (IL)-8, a major mediator of acute neutrophil-mediated inflammation, ...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/s0378-8741(02)00285-4

    authors： Oh GS,Pae HO,Choi BM,Jeong S,Oh H,Oh CS,Rho YD,Kim DH,Shin MK,Chung HT

    更新日期：2003-01-01 00:00:00

  • A semi-quantitative approach to the selection of appropriate candidate plant molluscicides--a South African application.

    abstract：:The high cost of synthetic molluscicides, used in the control of the intermediate snail hosts of schistosomiasis (bilharzia), has resulted in renewed interest in plant molluscicides. The history of the use of plant molluscicides is reviewed. Although screening programmes have been conducted in other African countries,...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/s0378-8741(96)01495-x

    authors： Clark TE,Appleton CC,Drewes SE

    更新日期：1997-03-01 00:00:00

  • Protective role of Anacardium occidentale extract against streptozotocin-induced diabetes in rats.

    abstract：:The protective effect of Anacardium occidentale aqueous extract against streptozotocin-induced diabetes was evaluated in rats. The rats were treated with 175 mg/kg of the extract per os, twice daily; beginning 2 days before streptozotocin (STZ) injection. A total of 3 days after STZ administration, there was a 48% inc...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/s0378-8741(97)00159-1

    authors： Kamtchouing P,Sokeng SD,Moundipa PF,Watcho P,Jatsa HB,Lontsi D

    更新日期：1998-09-01 00:00:00

  • Protective effects of Poria cocos and its components against cisplatin-induced intestinal injury.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Poria cocos (Schw.) Wolf (Poria) is a well-known traditional medicinal fungus. It has been considered to possess spleen-invigorating (Jianpi) effects in traditional Chinese medicine, and is used clinically to treat spleen deficiency (Pixu) with symptoms of intestinal disorders such as dia...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2020.113722

    authors： Zou YT,Zhou J,Wu CY,Zhang W,Shen H,Xu JD,Zhang YQ,Long F,Li SL

    更新日期：2021-04-06 00:00:00

  • Anti-inflammatory and analgesic properties of water-ethanolic extract from Pothomorphe umbellata (Piperaceae) aerial parts.

    abstract：:Anti-inflammatory and analgesic activities as well as the median lethal dose (LD50) of water-ethanolic extract (PHE) of the aerial parts of Pothomorphe umbellata were evaluated in animal models. The ED(50) (oral) for the inhibition of carrageenan-induced rat paw edema assay was determined to be 550 mg/kg, while the LD...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2005.02.023

    authors： Perazzo FF,Souza GH,Lopes W,Cardoso LG,Carvalho JC,Nanayakkara NP,Bastos JK

    更新日期：2005-06-03 00:00:00

  • Medical ethnobotany survey in Martinique.

    abstract：:From September 1990 to December 1994, the authors conducted an ethnobotanical survey within the population of Martinique. Two hundred and sixty-one plants used for medicinal purposes were gathered. It was possible to identify 251 species (96%). Traditional medicinal practices, although threatened by the modern pharmac...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/0378-8741(96)01425-0

    authors： Longuefosse JL,Nossin E

    更新日期：1996-09-01 00:00:00

  • Botany, phytochemistry, pharmacology, and potential application of Polygonum cuspidatum Sieb.et Zucc.: a review.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Polygonum cuspidatum Sieb. et Zucc. (Polygonum cuspidatum), also known as Reynoutria japonica Houtt and Huzhang in China, is a traditional and popular Chinese medicinal herb. Polygonum cuspidatum with a wide spectrum of pharmacological effects has been used for treatment of inflammation, ...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jep.2013.05.007

    authors： Peng W,Qin R,Li X,Zhou H

    更新日期：2013-07-30 00:00:00

  • Antibacterial activity and in vitro anti-tumor activity of the extract of the larvae of the housefly (Musca domestica).

    abstract：:One of the significant characteristics of traditional Chinese medicine is the use of insects, other terrestrial arthropods and their products as drugs. In the present work, the extract of housefly (Musca domestica) larvae was studied by an agar well diffusion assay and minimum bactericidal concentration (MBC) determin...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2006.11.015

    authors： Hou L,Shi Y,Zhai P,Le G

    更新日期：2007-05-04 00:00:00

  • Bioassay-guided isolation of active principles from Nigerian medicinal plants identifies new trypanocides with low toxicity and no cross-resistance to diamidines and arsenicals.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Leaves from the plant species studied herein are traditionally used in northern Nigeria against various protozoan infections. However, none of these herbal preparations have been standardized, nor have their toxicity to mammalian cells been investigated. In search of improved and non-toxi...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2017.03.028

    authors： Ebiloma GU,Igoli JO,Katsoulis E,Donachie AM,Eze A,Gray AI,de Koning HP

    更新日期：2017-04-18 00:00:00

  • Antioxidant and anti-inflammatory properties of Cardiospermum halicacabum and its reference compounds ex vivo and in vivo.

    abstract：AIMS OF THE STUDY:Cardiospermum halicacabum (CH) has been used in Chinese medicine for a long time. However, its fingerprint chromatogram, antioxidant, anti-inflammatory effects and mechanism are still needed to be explored. Therefore, the aims of this study investigated the antioxidant and anti-inflammatory effects of...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2010.11.005

    authors： Huang MH,Huang SS,Wang BS,Wu CH,Sheu MJ,Hou WC,Lin SS,Huang GJ

    更新日期：2011-01-27 00:00:00

  • Evaluation of the anti-inflammatory and analgesic activities of Liu-Shen-Wan and its individual fractions.

    abstract：:Liu-Shen-Wan (LSW), a famous traditional Chinese medicine for treatment of upper respiratory tract inflammation, was evaluated for its anti-inflammatory and analgesic activities. Acetic acid-elevated vascular permeability, carboxymethylcellulose sodium (CMC-Na)-induced leukocyte migration and ear edema induced by picr...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2007.02.008

    authors： Ma HY,Kou JP,Wang JR,Yu BY

    更新日期：2007-05-30 00:00:00

  • The genus Pterocaulon (Asteraceae) - A review on traditional medicinal uses, chemical constituents and biological properties.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Species of the genus Pterocaulon (Asteraceae) are used in different parts of the world for treating skin and liver diseases, as well as disorders of the respiratory system, among others. AIM OF THE STUDY:This review aims to discuss the present state of the art concerning the ethnobotanic...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jep.2018.06.012

    authors： Medeiros-Neves B,Teixeira HF,von Poser GL

    更新日期：2018-10-05 00:00:00

  • Production of Th1- and Th2-dependent cytokines induced by the Chinese medicine herb, Rhodiola algida, on human peripheral blood monocytes.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Rhodiola algida, an herb ingredient used in Chinese medicine, has been clinically proven to be effective in enhancing human immune responses. AIM OF STUDY:This study attempted to identify the potential immunomodulatory effect of Rhodiola algida extract in human immune system in vitro, an...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2009.03.009

    authors： Li HX,Sze SC,Tong Y,Ng TB

    更新日期：2009-06-22 00:00:00

  • In vitro antiprotozoal activity and cytotoxicity of extracts and isolated constituents from Greenwayodendron suaveolens.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:The Nkundo people (Nkundo area of Bolongo, Mai-Ndombe district, Bandundu Province, DR Congo) use various plant parts of the tree Greenwayodendron suaveolens (Engl. & Diels) Verdc. (syn. Polyalthia suaveolens Engl. & Diels) (Annonaceae) against malaria, but its antiprotozoal constituents a...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2016.09.051

    authors： Muganza DM,Fruth B,Nzunzu JL,Tuenter E,Foubert K,Cos P,Maes L,Kanyanga RC,Exarchou V,Apers S,Pieters L

    更新日期：2016-12-04 00:00:00

  • In vitro purgative effect of Ruellia praetermissa. Sceinf.ex.Lindau (Acanthaceae).

    abstract：:Methanol, ethylacetate and aqueous extracts of Ruellia praetermissa initiated spontaneous contractions in the quiescent and increased contraction on the electrically stimulated ileal strip at a concentration of 30 microg/ml. The extracts produced concentration-related contractions both in amplitude and tone up till 75...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/s0378-8741(00)00204-x

    authors： Salah AM,Dongmo AB,Kamanyi A,Bopelet M,Vierling W,Wagner H

    更新日期：2000-09-01 00:00:00

  • Cytotoxicity of South-African medicinal plants towards sensitive and multidrug-resistant cancer cells.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Traditional medicine plays a major role for primary health care worldwide. Cancer belongs to the leading disease burden in industrialized and developing countries. Successful cancer therapy is hampered by the development of resistance towards established anticancer drugs. AIM:In the pres...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2016.04.005

    authors： Saeed MEM,Meyer M,Hussein A,Efferth T

    更新日期：2016-06-20 00:00:00

  • Protective Effects of Pistacia lentiscus L. fruit extract against calcium oxalate monohydrate induced proximal tubular injury.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:The world prevalence of kidney stones is increasing and plants are frequently used to treat urolithiasis. Pistacia lentiscus L, a plant which freely grows around the Mediterranean basin areas, is widely used for various pathologies. P. lentiscus has an important impact as it has economica...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2017.07.018

    authors： Cheraft-Bahloul N,Husson C,Ourtioualous M,Sinaeve S,Atmani D,Stévigny C,Nortier JL,Antoine MH

    更新日期：2017-09-14 00:00:00

  • A traditional herbal formula, Hyangsa-Pyeongwi san (HPS), improves quality of life (QoL) of the patient with functional dyspepsia (FD): randomized double-blinded controlled trial.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Hyangaa-Pyeongwi san is the most well known description in Traditional Chinese Medicine for treating functional gastrointestinal disorders. Functional dyspepsia (FD) is a main concern of intimidating quality of life (QoL) in recent days. Although many medicines have been developed to impr...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.jep.2013.10.033

    authors： Kim JB,Shin JW,Kang JY,Son CG,Kang W,Lee HW,Lee DS,Park YC,Cho JH

    更新日期：2014-01-01 00:00:00

  • Pharmacovigilance practice and risk control of Traditional Chinese Medicine drugs in China: current status and future perspective.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Traditional Chinese Medicine (TCM), including Traditional Chinese Medicine drugs (TCM drugs), has been playing a very important role in health protection and disease control for thousands of years in China. Relying on natural products, mainly of herbal origin, used either as raw materials...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jep.2012.01.058

    authors： Zhang L,Yan J,Liu X,Ye Z,Yang X,Meyboom R,Chan K,Shaw D,Duez P

    更新日期：2012-04-10 00:00:00

  • Metabolomics analysis to evaluate the antibacterial activity of the essential oil from the leaves of Cinnamomum camphora (Linn.) Presl.

    abstract：ETHNOPHARMACOLOGY RELEVANCE:Cinnamomum camphora (Linn.) Presl (C. camphora) is one of the oldest herbal medicines used as a traditional medicine, owning a wide range of biological functions including anti-bacterial, anti-oxidative, anti-fungal, anti-inflammatory, insecticidal and repellent activities. OBJECTIVE:The ai...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2020.112652

    authors： Chen J,Tang C,Zhang R,Ye S,Zhao Z,Huang Y,Xu X,Lan W,Yang D

    更新日期：2020-05-10 00:00:00

  • Ficus spp. (fig): ethnobotany and potential as anticancer and anti-inflammatory agents.

    abstract：:This review explores medieval, ancient and modern sources for ethnopharmacological uses of Ficus (fig) species, specifically for employment against malignant disease and inflammation. The close connection between inflammatory/infectious and cancerous diseases is apparent both from the medieval/ancient merging of these...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jep.2008.06.025

    authors： Lansky EP,Paavilainen HM,Pawlus AD,Newman RA

    更新日期：2008-09-26 00:00:00

  • Rokumi-jio-gan-containing prescriptions regulate oxidative stress through improving dyslipidemia in a subtotal nephrectomized rat model.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Rokumi-jio-gan-containing prescriptions, traditional medicine, are widely used to treat renal dysfunction in Japan. AIM OF THE STUDY:The present study was conducted to examine whether two Rokumi-jio-gan-containing prescriptions (Hachimi-jio-gan and Bakumi-jio-gan) have an ameliorative ef...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2013.04.036

    authors： Park CH,Lee SL,Noh JS,Yokozawa T

    更新日期：2013-07-09 00:00:00