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Protective role of Anacardium occidentale extract against streptozotocin-induced diabetes in rats.

Abstract：

:The protective effect of Anacardium occidentale aqueous extract against streptozotocin-induced diabetes was evaluated in rats. The rats were treated with 175 mg/kg of the extract per os, twice daily; beginning 2 days before streptozotocin (STZ) injection. A total of 3 days after STZ administration, there was a 48% increase in blood glucose level in pretreated rats, compared with a 208% increase in diabetic control rats treated with STZ alone. Furthermore, these pretreated animals presented no glycosuria, a normal weight gain and a non significant increase in food and fluid intake at the end of the treatment compared with the normal control. Diabetic control animals showed a positive glycosuria, body weight loss, a real polyphagia and polydypsia. These results indicate the protective role of Anacardium occidentale extract against the diabetogenic action of STZ.

journal_name

J Ethnopharmacol

journal_title

Journal of ethnopharmacology

authors

Kamtchouing P,Sokeng SD,Moundipa PF,Watcho P,Jatsa HB,Lontsi D

doi

10.1016/s0378-8741(97)00159-1

subject

Has Abstract

pub_date

1998-09-01 00:00:00

pages

95-9

issue

2

eissn

0378-8741

issn

1872-7573

pii

S0378-8741(97)00159-1

journal_volume

62

pub_type

杂志文章

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