Abstract:
ETHNOPHARMACOLOGICAL RELEVANCE:Dictamnus angustifolius (Rutaceae) has been used as an alternative for folk medicine, Dictamnus dasycarpus in the treatment of rheumatism, bleeding, itching, jaundice, chronic hepatitis, and skin diseases in Xinjiang Province of China. The aim of this study was to evaluate the antimicrobial and antioxidant activities of essential oil (EO) from Dictamnus angustifolius, correlated with their chemical composition and evaluate their cytotoxicity. MATERIALS AND METHODS:The EO were extracted by water-distillation using a Clevenger-type apparatus. The chemical composition of EO was identified by GC-MS analysis. The antimicrobial activity was evaluated against five microorganisms by the agar disc diffusion method and minimal inhibitory concentration (MIC) assay. The antioxidant activity was measured by employing DPPH and FRAP assays. The cytotoxic activity was evaluated in the mammalian cells lines A549, MCF7, B16 and LoVo using the MTT method to assess cell viability. RESULTS:52 compounds representing the 97.2% of the total oil were identified by GC/MS. The major constituents of the oil were tetramethylenecyclobutane (42.07%) and fraxinellone (19.06%). The antimicrobial activity showed that the EO possess significant inhibition in Monilia albican ATCC 10231 and Staphylococcus aureus ATCC 6538. The antioxidant activity suggested that the EO possess significant reducing power. The cytotoxic activity of the EO in MCF7 and LoVo cells was significant stronger than in the other cell lines. CONCLUSION:This study is the first characterization of the chemical composition and biological activities of EO from Dictamnus angustifolius. All experimental data indicate that the EO have not only remarkable antioxidant properties but also potential antimicrobial activity and cytotoxic activities.
journal_name
J Ethnopharmacoljournal_title
Journal of ethnopharmacologyauthors
Sun J,Wang X,Wang P,Li L,Qu W,Liang Jdoi
10.1016/j.jep.2014.06.055subject
Has Abstractpub_date
2015-01-15 00:00:00pages
296-300eissn
0378-8741issn
1872-7573pii
S0378-8741(14)00503-0journal_volume
159pub_type
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journal_title:Journal of ethnopharmacology
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journal_title:Journal of ethnopharmacology
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journal_title:Journal of ethnopharmacology
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journal_title:Journal of ethnopharmacology
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journal_title:Journal of ethnopharmacology
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journal_title:Journal of ethnopharmacology
pub_type: 历史文章,杂志文章
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journal_title:Journal of ethnopharmacology
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journal_title:Journal of ethnopharmacology
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journal_title:Journal of ethnopharmacology
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更新日期:2017-09-14 00:00:00
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journal_title:Journal of ethnopharmacology
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更新日期:2019-07-15 00:00:00
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journal_title:Journal of ethnopharmacology
pub_type: 历史文章,杂志文章
doi:10.1016/j.jep.2011.02.030
更新日期:2011-05-17 00:00:00
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journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2013.02.010
更新日期:2013-04-19 00:00:00
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journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/s0378-8741(98)00201-3
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abstract:AIM:To investigate the therapeutic effects and mechanisms of total flavonoids of Turpinia Arguta Seen (TFS) on adjuvant arthritis in rats. METHODS:The model of adjuvant arthritis was induced by injection of Freund's Complete Adjuvant (FCA). Secondary paw swelling of AA rats was measured with volume meter and polyarthr...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2007.11.027
更新日期:2008-02-28 00:00:00
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journal_title:Journal of ethnopharmacology
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journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2016.06.005
更新日期:2016-08-22 00:00:00
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journal_title:Journal of ethnopharmacology
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doi:10.1016/j.jep.2007.03.035
更新日期:2007-07-25 00:00:00
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journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
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更新日期:1994-05-01 00:00:00
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journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2016.12.017
更新日期:2017-02-23 00:00:00
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journal_title:Journal of ethnopharmacology
pub_type: 杂志文章,评审
doi:10.1016/j.jep.2013.08.051
更新日期:2013-10-28 00:00:00
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journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2011.07.018
更新日期:2011-09-02 00:00:00
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journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2009.02.013
更新日期:2009-05-04 00:00:00
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journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/s0378-8741(98)00126-3
更新日期:1999-11-30 00:00:00
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journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2017.09.002
更新日期:2018-01-10 00:00:00
abstract::Keishi-bukuryo-gan (TJ-25) is a traditional Chinese herbal remedy containing five components: bark of Cinnamomum cassia, root of Paeonia lactiflora, seed of Prunus persica or P. persiba var. davidiana, carpophores of Poria cocos and root bark of Paeonia suffruticosa. This preparation has been used in the treatment of ...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/0378-8741(88)90002-5
更新日期:1988-07-01 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Prostate cancer is a major problem worldwide and affects most men above the age of forty-five. Vernonia guineensis Benth. (Asteraceae) root decoction is used in folk medicine in Cameroon to treat a number of ailments including prostate cancer. The aim of this study was to provide a prelim...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
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更新日期:2012-06-14 00:00:00
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journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/s0378-8741(98)00135-4
更新日期:1999-03-01 00:00:00