Therapeutic effects and mechanisms of total flavonoids of Turpinia Arguta Seen on adjuvant arthritis in rats.


AIM:To investigate the therapeutic effects and mechanisms of total flavonoids of Turpinia Arguta Seen (TFS) on adjuvant arthritis in rats. METHODS:The model of adjuvant arthritis was induced by injection of Freund's Complete Adjuvant (FCA). Secondary paw swelling of AA rats was measured with volume meter and polyarthritis index were scored. The splenocyte proliferation, (interleukin-1) IL-1 and interleukin-2 (IL-2) production were assayed by cell proliferation assay. Prostaglandin E(2) (PGE(2)) production was determined by radioimmunoassay. RESULTS:TFS (80, 160, 320 mg/kg, i.g.) could significantly inhibit secondary inflammatory reaction (secondary swelling, multiple arthritis, pathologic change of ankle arthritis) in AA rats. The results in vivo showed that the low response of splenocytes to concanavalin A (Con A) and lipopolysaccharide (LPS) and the decreased IL-2 synthesis were restored in AA rats treated with TFS (160, 320 mg/kg, i.g.), while the elevated IL-1 and PGE(2) released from peritoneal macrophages (PMphi) were also reduced. CONCLUSION:TFS has significant therapeutic effect on AA rats, which might be relate to its immunoregulatory actions.


J Ethnopharmacol


Zhang L,Li J,Yu SC,Jin Y,Lv XW,Zou YH,Li Y




Has Abstract


2008-02-28 00:00:00














  • An assessment of the Bhutanese traditional medicine for its ethnopharmacology, ethnobotany and ethnoquality: Textual understanding and the current practices.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:: This study involves the assessment of the Bhutanese traditional medicine (BTM) which was integrated with the mainstream biomedicine in 1967 to provide primary health care services in the country. It caters to 20-30% of the daily out-patients within 49 traditional medicine units attached...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Wangchuk P,Pyne SG,Keller PA

    更新日期:2013-06-21 00:00:00

  • Effects of the Turkish subspecies of Viscum album on macrophage-derived cytokines.

    abstract::Viscum album L. herbs are used for the treatment of various diseases. Apart from their immunostimulatory, antitumor, and hypotension inducing activities, anti-inflammatory effects has also been recorded in the literature. Since the immunostimulatory activity of mistletoe is mainly attributed to a stimulation of the mo...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Yesilada E,Deliorman D,Ergun F,Takaishi Y,Ono Y

    更新日期:1998-07-01 00:00:00

  • Antiurolithiatic activity of Boldoa purpurascens aqueous extract: An in vitro and in vivo study.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Boldoa purpurascens Cav. (Nyctaginaceae) is a plant species used in traditional medicine in Cuba as antiurolithiatic. AIM OF THE STUDY:The aim of the present investigation was to evaluate the in vitro and in vivo antiurolothiatic activity of an aqueous extract from the leaves of Boldoa p...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Mosquera DMG,Ortega YH,Quero PC,Martínez RS,Pieters L

    更新日期:2020-05-10 00:00:00

  • Protective effects of Zhibai Dihuang Wan on renal tubular cells affected with gentamicin-induced apoptosis.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Zhibai Dihuang Wan (ZDW) is an ancient traditional Chinese medicine composed of eight herbal ingredients and has been used to treat chronic kidney inflammation and diabetes for thousands of years. Nonetheless, the influence of ZDW on acute kidney injury is still unknown. We intended to id...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Hsu YH,Chen TH,Wu MY,Lin YF,Chen WL,Cheng TH,Chen CH

    更新日期:2014-01-01 00:00:00

  • The methanol extract of Spiraea prunifolia var. simpliciflora root inhibits the generation of nitric oxide and superoxide in RAW 264.7 cells.

    abstract::It is well established that nitric oxide (NO) and superoxide radicals play pivotal roles in the pathogenesis of inflammatory diseases and fever. This study is undertaken to address whether the methanol extract of Spiraea prunifolia var. simpliciflora root, a traditional medicine as an antipyretic, modulates the genera...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: So HS,Park R,Oh HM,Pae HO,Lee JH,Chai KY,Chung SY,Chung HT

    更新日期:1999-12-15 00:00:00

  • Screening of seven selected Rwandan medicinal plants for antimicrobial and antiviral activities.

    abstract::Aqueous EtOH (80%) extracts of seven plants used by Rwandan traditional healers to treat infections, were screened for antibacterial, antifungal, and antiviral activities. Only two of the selected plants showed a true antiviral activity against herpes simplex virus type 1, while all of them exhibited virucidal propert...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Sindambiwe JB,Calomme M,Cos P,Totté J,Pieters L,Vlietinck A,Vanden Berghe D

    更新日期:1999-04-01 00:00:00

  • The suppressive effects of Saposhnikovia divaricata (Fangfeng) chromone extract on rheumatoid arthritis via inhibition of nuclear factor-κB and mitogen activated proteinkinases activation on collagen-induced arthritis model.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Saposhnikovia divaricata (SD), called "Fangfeng" in China, is commonly used in clinical compound prescription for treatment of rheumatoid arthritis (RA), but its actions on RA have not been clarified. The present study aims to determine the anti-inflammatory activity of SD chromone extrac...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Kong X,Liu C,Zhang C,Zhao J,Wang J,Wan H,Zhu H,Zhang P,Chen W,Xiao Y,Lin N

    更新日期:2013-07-30 00:00:00

  • Antiosteoporotic effect of Hemidesmus indicus Linn. on ovariectomised rats.

    abstract:PHARMACOLOGICAL RELEVANCE:Root of Hemidesmus indicus (L). R. Br., an herbal drug of India is traditionally used to prevent or treat female hormonal disturbance related disorders and assuaging symptoms of menopausal conditions. AIM OF THE STUDY:Lack of scientific data for potential use in bone loss, the present study w...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Desai S,Babaria P,Nakarani M,Shah K,Paranjape A

    更新日期:2017-03-06 00:00:00

  • Inhibitory effects of 1-O-methyl-fructofuranose from Schisandra chinensis fruit on melanogenesis in B16F0 melanoma cells.

    abstract:AIM OF THE STUDY:1-O-methyl-fructofuranose (1-O-MFF) from the fruit of Schisandra chinensis is a traditional Korean medicinal herb that has a variety of beneficial properties. The effect of purified 1-O-MFF on melanogenesis including the activation of related signaling pathways was investigated. MATERIALS AND METHODS:...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Oh EY,Jang JY,Choi YH,Choi YW,Choi BT

    更新日期:2010-10-28 00:00:00

  • Ethanol extraction preparation of American ginseng (Panax quinquefolius L) and Korean red ginseng (Panax ginseng C.A. Meyer): differential effects on postprandial insulinemia in healthy individuals.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Ginsenosides are the proposed bioactive constituent of ginseng, especially for the attenuation of postprandial glycemia (PPG). The efficacious proportion of total and specific ginsenosides, remains unknown. Alcohol extraction of whole ginseng root can be used to selectively manipulate the...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章,随机对照试验


    authors: De Souza LR,Jenkins AL,Jovanovski E,Rahelić D,Vuksan V

    更新日期:2015-01-15 00:00:00

  • β-carboline alkaloids attenuate bleomycin induced pulmonary fibrosis in mice through inhibiting NF-kb/p65 phosphorylation and epithelial-mesenchymal transition.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:The plant Arenaria kansuensis is used in traditional medicine to treat lung inflammation for a long time. However, the anti-pulmonary fibrosis effect and its corresponding bioactive constituents of this plant have not been studied extensively. AIM OF THE STUDY:The purpose of this study w...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Cui Y,Jiang L,Yu R,Shao Y,Mei L,Tao Y

    更新日期:2019-10-28 00:00:00

  • Antidiabetic, anti-oxidant and antimicrobial activities of Fadogia ancylantha extracts from Malawi.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Communities in Chilumba, Malawi use herbal tea prepared from Fadogia ancylantha Schweinf (Rubiaceae) leaves for the management of diabetes, hypertension and alleviation of symptoms of gastrointestinal disorders and pneumonia. The objective of the study was to evaluate the in vitro antidia...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Nyirenda KK,Saka JD,Naidoo D,Maharaj VJ,Muller CJ

    更新日期:2012-08-30 00:00:00

  • The hypoglucemic effect of Opuntia streptacantha studied in different animal experimental models.

    abstract::Studies performed with Opuntia streptacantha sap in three different animal species using several experimental conditions are described. The Opuntia sap induced hypoglucemic effects when orally administered to intact animals under induced states of moderate increase of blood sugar. In normoglucemic and pancreatectomize...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Ibañez-Camacho R,Meckes-Lozoya M,Mellado-Campos V

    更新日期:1983-03-01 00:00:00

  • Aconitum in traditional Chinese medicine: a valuable drug or an unpredictable risk?

    abstract::Aconitum species have been used in China as an essential drug in Traditional Chinese Medicine (TCM) for 2000 years. Reviewing the clinical application of Aconitum, their pharmacological effects, toxicity and detoxifying measures, herb-herb interactions, clinical taboos, famous herbal formulas, traditional and current ...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章,评审


    authors: Singhuber J,Zhu M,Prinz S,Kopp B

    更新日期:2009-10-29 00:00:00

  • Effects of dichloromethane and butanol fractions of Gochnatia polymorpha floccosa in maternal reproductive outcome, embryo-fetal development and DNA integrity in mice.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Gochnatia polymorpha ssp. floccosa (Asteraceae) also known as ''Cambará'' is used as medicinal plant in Brazil to treat infections and inflammation. Previous studies showed that its ethanolic extract could be bioprospecting of a new anti-inflammatory phytotherapy for use during pregnancy....

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Pessatto LR,Auharek SA,Gonçalves CA,de David N,Monreal AC,Kassuya CA,Antoniolli-Silva AC,Stefanello MÉ,Oliveira RJ

    更新日期:2017-03-22 00:00:00

  • Quantitative market survey of non-woody plants sold at Kariakoo Market in Dar es Salaam, Tanzania.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:In Tanzania, traditional medicine plays a significant role in health care and local economies based on the harvesting, trade and sale of medicinal plant products. The majority of this plant material is said to originate from wild sources, and both traditional healers and vendors are conce...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Posthouwer C,Veldman S,Abihudi S,Otieno JN,van Andel TR,de Boer HJ

    更新日期:2018-08-10 00:00:00

  • Ethnobotanical and ethnomedicinal studies in Baluchi tribes: A case study in Mt. Taftan, southeastern Iran.

    abstract:ETHNOBOTANICAL RELEVANCE:From ancient times, the applied use of herbs has been common among indigenous people throughout the world. The present survey is a regional ethnobotanical study of Baluchi tribes living in the Mt. Taftan area, Sistan and Baluchistan Province, southeastern Iran. The aim of this study was to docu...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Maleki T,Akhani H

    更新日期:2018-05-10 00:00:00

  • The comparative clinical study of efficacy of Gamisoyo-San (Jiaweixiaoyaosan) on generalized anxiety disorder according to differently manufactured preparations: multicenter, randomized, double blind, placebo controlled trial.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Gamisoyo-San (GSS) is a well-known Traditional Korean Medicine shown to be effective on mood disorders. AIM OF THE STUDY:The purpose of this research is to examine the effect of Gamisoyo-San on generalized anxiety disorder by its differently manufactured preparations. MATERIALS AND METH...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章,多中心研究,随机对照试验


    authors: Park DM,Kim SH,Park YC,Kang WC,Lee SR,Jung IC

    更新日期:2014-12-02 00:00:00

  • Cytotoxic and genotoxic effects of defence secretion of Ulomoides dermestoides on A549 cells.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Ulomoides dermestoides (Fairmaire, 1893) is a cosmopolitan tenebrionid beetle reared by Argentine people who consume them alive as an alternative medicine in the treatment of different illnesses such as asthma, Parkinson's, diabetes, arthritis, HIV and specially cancer. AIM OF THE STUDY:...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Crespo R,Villaverde ML,Girotti JR,Güerci A,Juárez MP,de Bravo MG

    更新日期:2011-06-14 00:00:00

  • Inhibitory activity of Chrysanthemi sibirici herba extract on RBL-2H3 mast cells and compound 48/80-induced anaphylaxis.

    abstract::The effects of extracts from various oriental medicinal herbs on mast cell-mediated allergic reaction were investigated. Among them, Chrysanthemi sibirici herba ethanol extract exerted the potent inhibitory activity on antigen-induced degranulation in RBL-2H3 mast cells. Chrysanthemi sibirici herba dose-dependently in...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Lee JH,Seo JY,Ko NY,Chang SH,Her E,Park T,Lee HY,Han JW,Kim YM,Choi WS

    更新日期:2004-12-01 00:00:00

  • Aqueous root extracts from Mimosa albida Humb. & Bonpl. ex Willd display antinociceptive activity in mice.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:In this work, we study whether aqueous extracts from the roots of Mimosa albida Humb. & Bonpl. ex Willd, a plant known in the Highlands of Chiapas, Mexico as "Lotóm chíx" are endowed with both antinociceptive and anxiolytic effects. MATERIALS AND METHODS:ICR mice were systemically treate...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Rejón-Orantes JC,Suaréz DP,Rejón-Rodríguez A,Hernández SH,Liévano OE,Rodríguez DL,de la Mora MP

    更新日期:2013-09-16 00:00:00

  • Metabolomic strategy to study therapeutic and synergistic effects of tanshinone IIA, salvianolic acid B and ginsenoside Rb1 in myocardial ischemia rats.

    abstract:AIM OF THE STUDY:Tanshinone IIA (T), salvianolic acid B (S) and ginsenoside Rb1 (G) are the three major active ingredients of Compound Danshen Formula (CDF) for its protective effects on myocardial ischemia (MI). In this study, we aimed to investigate therapeutic and synergistic effects of TSG (combination of T, S and ...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Lu Y,Liu X,Liang X,Xiang L,Zhang W

    更新日期:2011-03-08 00:00:00

  • Chemical composition, antioxidant and anti-inflammatory activities of the essential oils from male and female specimens of Baccharis punctulata (Asteraceae).

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Baccharis punctulata (Asteraceae), popularly known as "Chíllka saru saru" in Bolivia, has been used by rural communities in Bustillo Province of the Potosi Department for treatment of asthma, luxations and contusions. AIM OF THE STUDY:To analyze the chemical composition of the essential ...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Ascari J,de Oliveira MS,Nunes DS,Granato D,Scharf DR,Simionatto E,Otuki M,Soley B,Heiden G

    更新日期:2019-04-24 00:00:00

  • Effects of mitragynine from Mitragyna speciosa Korth leaves on working memory.

    abstract:AIM OF THE STUDY:Mitragyna speciosa Korth from Rubiaceae family is a tropical plant indigenous to Southeast Asia particularly in Thailand, Peninsular of Malaysia and Indonesia. The leaves have been used by natives for their opium-like effect and cocaine-like stimulant ability to combat fatigue and enhance tolerance to ...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Apryani E,Hidayat MT,Moklas MA,Fakurazi S,Idayu NF

    更新日期:2010-06-16 00:00:00

  • Ethnoveterinary knowledge and practices at Colares Island, Pará state, eastern Amazon, Brazil.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:The lack of ethnoveterinary surveys in Brazil, especially in the Amazon region, results in losses in the veterinary phytopharmacology field and in scientific documentation of the cultural traditions of plant use in the treatment of animal diseases. AIM OF THE STUDY:To catalog, analyze an...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Ritter RA,Monteiro MV,Monteiro FO,Rodrigues ST,Soares ML,Silva JC,Palha Md,Biondi GF,Rahal SC,Tourinho MM

    更新日期:2012-11-21 00:00:00

  • Patients' experiences attributed to the use of Passiflora incarnata: A qualitative, phenomenological study.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Passiflora incarnata Linnaeus (Passiflora incarnata) was established as a medicinal plant in Europe in the middle of the 19th century. Since then, it has been used for the treatment of anxiety, sleep disorders and restlessness in Western European phytotherapy. This study provides insights...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Canella C,Bachmann C,Wolfensberger B,Witt CM

    更新日期:2019-03-01 00:00:00

  • Increase of ejaculatory capacity by systemic administration of the oquichpatli (Senecio cardiophyllus) aqueous crude extract in male rats.

    abstract:AIM OF THE STUDY:To analyse the pro-ejaculatory properties of the proverbial Mexican plant oquichpatli, Senecio cardiophyllus, in an animal model for the study of ejaculation in spinal and anaesthetised male rats. MATERIALS AND METHODS:The aqueous crude extract of Senecio cardiophyllus (at 0.4, 1.2 and 4 mg/kg) was i....

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Carro-Juárez M,Alcazar C,Ballesteros-Polvo E,Villalobos-Peñalosa P

    更新日期:2009-12-10 00:00:00

  • Dalspinin isolated from Spermacoce hispida (Linn.) protects H9c2 cardiomyocytes from hypoxic injury by modulating oxidative stress and apoptosis.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Spermacoce hispida (S.hispida), a potential medicinal plant has been traditionally used as an antibacterial, antieczemic, antihypertensive, antidiabetic and antihyperlipidemic agent. Although, this plant has been claimed to protect against oxidative injury and inflammatory conditions in r...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Lakshmi Sundaram R,Vasanthi HR

    更新日期:2019-09-15 00:00:00

  • Viscum articulatum Burm. f. aqueous extract exerts antiproliferative effect and induces cell cycle arrest and apoptosis in leukemia cells.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Viscum articulatum Burm. f. (leafless mistletoe) has been used in traditional system of medicines in India, China, Taiwan, Cambodia, Laos, and Vietnam, to treat blood-related diseases and various inflammatory and degenerative diseases including cancer. Anticancer activities of some phytom...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Mishra R,Sharma S,Sharma RS,Singh S,Sardesai MM,Sharma S,Mishra V

    更新日期:2018-06-12 00:00:00

  • Prevention of UV radiation-induced cutaneous photoaging in mice by topical administration of patchouli oil.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Pogostemon cablin has been widely used in traditional Chinese medicine for the treatment of many diseases, including skin disorders. In the skin beauty and care prescriptions, Pogostemon cablin is one of the top ten frequently used traditional Chinese medicines. AIM OF THE STUDY:The pres...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Lin RF,Feng XX,Li CW,Zhang XJ,Yu XT,Zhou JY,Zhang X,Xie YL,Su ZR,Zhan JY

    更新日期:2014-06-11 00:00:00