Xanthine oxidase inhibitory activity of some Panamanian plants from Celastraceae and Lamiaceae.

Abstract:

:Thirty four crude extracts of Panamanian plants, from nine species of Celastraceae and Lamiaceae, were assayed for xanthine oxidase (XO) inhibitory activity. The enzymatic activity was estimated by measuring the increase in absorbance at 290 nm due to uric acid formation. Eighty five percent of the crude extracts were found to possess XO inhibitory activity at 50 micrograms/ml and all the extracts of the species from Lamiaceae were active even at 1 micrograms/ml. The ethanol extracts of Hyptis obtusiflora Presl ex Benth. (Lamiaceae) and H. lantanaefolia Poit. (Lamiaceae) exhibited the highest activity with an inhibition of approximately 40% at 1 micrograms/ml.

journal_name

J Ethnopharmacol

authors

González AG,Bazzocchi IL,Moujir L,Ravelo AG,Correa MD,Gupta MP

doi

10.1016/0378-8741(95)01225-3

subject

Has Abstract

pub_date

1995-04-01 00:00:00

pages

25-9

issue

1

eissn

0378-8741

issn

1872-7573

pii

0378874195012253

journal_volume

46

pub_type

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