Abstract:
:(-)-Edunol a prenylated pterocarpan was isolated from the roots of two Mexican 'snakeweeds', Brongniartia podalyrioides and B. intermedia (Leguminosae). Edunol (3.1 mg/kg, i.p.) reduced the expected mortality of mice previously treated by the same route with the LD50 of the venom of the serpent Bothrops atrox. The molecular structure and properties of edunol are similar to those previously reported for cabenegrins A-I and A-II.
journal_name
J Ethnopharmacoljournal_title
Journal of ethnopharmacologyauthors
Reyes-Chilpa R,Gómez-Garibay F,Quijano L,Magos-Guerrero GA,Ríos Tdoi
10.1016/0378-8741(94)90086-8subject
Has Abstractpub_date
1994-05-01 00:00:00pages
199-203issue
3eissn
0378-8741issn
1872-7573pii
0378-8741(94)90086-8journal_volume
42pub_type
杂志文章abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Indigofera argentea Burm. f.; commonly known as neel, jantari, hathio; is traditionally used for the treatment of headache, fever, inflammation and body pain. Local communities also used this plant for the treatment of malaria, jaundice, vertigo and gastric disorders. AIM OF THE STUDY:Th...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2020.112966
更新日期:2020-09-15 00:00:00
abstract::The combined effects of 5-fluorouracil (5-FU) and carp (Cyprinus carpio L.) extract on antitumor activity, myelotoxicity and gastrointestinal toxicity were examined in sarcoma 180-bearing mice. Carp extract was found to prevent the occurrence of myelotoxicity as determined by the reduction of leukocyte number, and of ...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/s0378-8741(99)00126-9
更新日期:1999-12-15 00:00:00
abstract::Hemidesmus indicus has been shown to possess significant activity against immunotoxicity and other pharmacological and physiological disorders. In this communication, we have shown the modulating effect of H. indicus on cumene hydroperoxide-mediated cutaneous oxidative stress and tumor promotion response in murine ski...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/s0378-8741(02)00360-4
更新日期:2003-03-01 00:00:00
abstract::The leaves of Moringa oleifera Lam (Moringaceae) are used by the Indians in their herbal medicine as a hypocholesterolemic agent in obese patients. The scientific basis for their use in hypercholesterolemia was therefore examined. It was found that administration of the crude leaf extract of Moringa oleifera along wit...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/s0378-8741(99)00106-3
更新日期:2000-01-01 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Renal fibrosis (RF) is a common outcome of various progressive chronic kidney diseases (CKDs) and, thus, seriously endangers human health. As the active ingredient of Amygdalus mongolica, amygdalin inhibits RF. Furthermore, our previous studies demonstrated that n-butanol extract (BUT) an...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2020.112858
更新日期:2020-07-15 00:00:00
abstract::Opuntia ficus indica cladodes are used in traditional medicine of many countries for their cicatrisant activity. The major components of cladodes are carbohydrate-containing polymers, which consist of a mixture of mucilage and pectin. In this paper we studied the cytoprotective effects of cladodes on experimental etha...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/s0378-8741(02)00243-x
更新日期:2002-12-01 00:00:00
abstract::An analysis of information obtained from interviews with 660 older native inhabitants of the southern Appalachian region in the United States indicates that plant foods, especially cultivars and materials processed from them, and some wildcrafted plant foods as well, constituted the bulk of the folk materia medica in ...
journal_title:Journal of ethnopharmacology
pub_type: 历史文章,杂志文章
doi:10.1016/j.jep.2006.04.008
更新日期:2006-11-03 00:00:00
abstract:AIM OF THE STUDY:Typhonium flagelliforme (Lodd.) Blume (Araceae) is a Malaysian plant used locally to combat cancer. In order to evaluate its antiproliferative activity in vitro and to possibly identify the active chemical constituents, a bioactivity guided study was conducted on the extracts of this plant. MATERIALS ...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2008.02.034
更新日期:2008-06-19 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:In Southern Europe Olea europaea leafs are known as a folk remedy for hypertension. Cardiovascular diseases are still the leading causes of morbidity and mortality in industrialized countries with hypertension being one of the main risk factors. AIM OF THE STUDY:We investigated effects o...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2008.08.018
更新日期:2008-11-20 00:00:00
abstract:AIM OF STUDY:Solanum lyratum herba (SLH) has been traditionally used for the treatment of febrifuge, diarrhea, eye disease and cancer with little scientific evidences. Thus, in the present study, to elucidate the antitumor mechanism of SLH: in vitro and in vivo experiments were performed with hexane fraction of Solanum...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2009.02.013
更新日期:2009-05-04 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Propolis has been employed extensively in many cultures since ancient times as antiseptic, wound healing, anti-pyretic and others due to its biological and pharmacological properties, such as immunomodulatory, antitumor, anti-inflammatory, antioxidant, antibacterial, antiviral, antifungal...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2019.112174
更新日期:2019-12-05 00:00:00
abstract::The hypoglycemic effects of water, ethanolic and butanolic extracts prepared from the root of Malmea depressa (Baill) R.E. Fries. (Annonaceae) were studied in diabetic rats (streptozotocin induced). Oral application of water extracts at doses of 40 and 80 mg/kg, ethanolic (112 mg/kg) and butanolic (80 mg/kg) extracts ...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2005.03.021
更新日期:2005-09-14 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Gastrodia elata Blume (Fam. Orchidaceae) is a traditional Chinese herbal medicine for treating headaches, dizziness, tetanus, epilepsy, and numbness of the limbs, which suggests that it has neuroprotective effect. AIM OF THE STUDY:To validate the neuroprotection of Gastrodia elata in pre...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2011.08.075
更新日期:2011-10-31 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Celosia argentea L. (Amaranthaceae), popularly known as "crista de galo", is used in folk medicine due to its diuretic and hypotensive effects. However, there are no reports in the literature regarding its pharmacological effects on the cardiovascular system as well as no data proving the...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2018.09.027
更新日期:2019-01-30 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Meta-analysis (MA) on Chinese herbal medicine (CHM) trials is increasingly published and indexed in major international databases but their trustworthiness and clinical applicability is uncertain. We aimed to assess the characteristics and methodological quality of MA on CHM. MATERIALS A...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章,评审
doi:10.1016/j.jep.2014.12.028
更新日期:2015-03-13 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:In this work, we study whether aqueous extracts from the roots of Mimosa albida Humb. & Bonpl. ex Willd, a plant known in the Highlands of Chiapas, Mexico as "Lotóm chíx" are endowed with both antinociceptive and anxiolytic effects. MATERIALS AND METHODS:ICR mice were systemically treate...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2013.07.010
更新日期:2013-09-16 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Huangqi Jianzhong Tang (HQJZ), a celebrated traditional Chinese medicine (TCM), is commonly used for treatment of chronic atrophic gastritis (CAG) in China. AIM OF THE STUDY:We aimed to screen out the material basis of HQJZ against CAG. MATERIALS AND METHODS:CAG rat model was constructe...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2018.05.015
更新日期:2018-09-15 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:In agreement with ethnomedicinal reports, the dichloromethane extract of Ageratum conyzoides L. (Asteraceae) was recently shown to be of considerable activity against Trypanosoma brucei rhodesiense, the etiologic agent of East African Human Trypanosomiasis (East African Sleeping Sickness)...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2011.06.015
更新日期:2011-09-01 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Over a 120 South African medicinal plants are used for the treatment of oral diseases. Despite the vast collection of antimicrobial studies being done on South African plants, there is still limited research on pathogens associated with oral infections. In consultation with the available ...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2017.09.002
更新日期:2018-01-10 00:00:00
abstract::The in vitro antiplasmodial activity of seven EtOH extracts and twenty fractions from the partition of the initial ethanolic extracts from seven African medicinal plants used in the Democratic Republic of Congo (DR Congo) for the treatment of malaria was evaluated. The most active EtOH extracts (IC50 < 3 microg/ml) we...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2004.02.022
更新日期:2004-07-01 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Dalbergia pinnata (Lour.) Prain (D. pinnata) is a plant widely distributed in tropical and subtropical regions of Asia, Africa, and the Americas. In humans, it is used in the prevention and treatment of diseases such as respiratory system, digestive system, cardiovascular and cerebrovascu...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2020.112731
更新日期:2020-05-23 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Soup prepared from the foot of fresh water edible snail, Bellamya bengalensis, is traditionally consumed by the tribes of Jharkhand against rheumatism like bone and joint inflammation. As rheumatism has underlying involvement of cell mediated hypersensitivity, in vivo delayed-type hyperse...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2014.09.009
更新日期:2014-11-18 00:00:00
abstract::The present study indicates the efficacy of extracts and fractions of Quercus lusitania var. infectoria galls (Oliv.) as larvicidal agents and their possible use in biological control of Culex pipiens, the urban nuisance mosquito. Extracts and fractions were tested against second and fourth instar larvae. The LC(50) v...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/s0378-8741(01)00390-7
更新日期:2002-02-01 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Ethnopharmacological investigations of traditional medicines have made significant contributions to plant-derived drugs, as well as the advancement of pharmacology. Drug discovery from medicinal flora is more complex than generally acknowledged because plants are applied for different the...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2016.12.044
更新日期:2017-02-23 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Wound healing is an important area of research in contemporary medicine. Unani is a traditional medicine system based on hundreds of years of observations and experiences. Wounds are described under the headings qarha (arabic) and jarāhat (persian) in classical Unani texts. Several drugs ...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章,评审
doi:10.1016/j.jep.2020.112878
更新日期:2020-07-15 00:00:00
abstract:AIM OF STUDY:Sjogren's syndrome (SS) is an autoimmune disorder characterized by lymphocytic infiltration of salivary and lacrimal glands leading to xerostomia and keratoconjunctivitis sicca. Evidence has accumulated suggesting that a Th1/Th2 cytokine imbalance has a role in the pathogenesis of SS. Currently, only palli...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2007.08.014
更新日期:2007-11-01 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Saposhnikovia divaricata (SD), called "Fangfeng" in China, is commonly used in clinical compound prescription for treatment of rheumatoid arthritis (RA), but its actions on RA have not been clarified. The present study aims to determine the anti-inflammatory activity of SD chromone extrac...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2013.05.023
更新日期:2013-07-30 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Traditional Chinese Medicine (TCM) has many obvious advantages in the treatment of chronic conditions such as urinary tract infection (UTI). Dongbai-Tonglin-Fang (DBTL), a Chinese herbal formula, has been used for the treatment of UTI for more than 40 years with proven efficacy. However, ...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2019.112028
更新日期:2019-09-15 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:[corrected] The seeds of Syzygium cumini, Skeels (Jamun) are extensively used in India for treatment of diabetes and other ailments. AIM OF THE STUDY:The aim of this work was to assess the role of Jamun seed extract (JSE) as a chemoprotective agent against in vivo oxidative stress and ge...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2010.12.014
更新日期:2011-03-24 00:00:00
abstract::Recent research suggests that, in addition to the well-documented occurrence of significant quantities of cocaine and related alkaloids in a limited number of species, the genus Erythroxylon will prove to be a rich source of tropane alkaloids. These bases are esters of a range of acids with tropine, 3 alpha, 6 beta-di...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/0378-8741(81)90057-x
更新日期:1981-03-01 00:00:00