Preliminary results on the protective effect of (-)-edunol, a pterocarpan from Brongniartia podalyrioides (Leguminosae), against Bothrops atrox venom in mice.

Abstract:

:(-)-Edunol a prenylated pterocarpan was isolated from the roots of two Mexican 'snakeweeds', Brongniartia podalyrioides and B. intermedia (Leguminosae). Edunol (3.1 mg/kg, i.p.) reduced the expected mortality of mice previously treated by the same route with the LD50 of the venom of the serpent Bothrops atrox. The molecular structure and properties of edunol are similar to those previously reported for cabenegrins A-I and A-II.

journal_name

J Ethnopharmacol

authors

Reyes-Chilpa R,Gómez-Garibay F,Quijano L,Magos-Guerrero GA,Ríos T

doi

10.1016/0378-8741(94)90086-8

subject

Has Abstract

pub_date

1994-05-01 00:00:00

pages

199-203

issue

3

eissn

0378-8741

issn

1872-7573

pii

0378-8741(94)90086-8

journal_volume

42

pub_type

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