Abstract:
:The hypoglycemic effects of water, ethanolic and butanolic extracts prepared from the root of Malmea depressa (Baill) R.E. Fries. (Annonaceae) were studied in diabetic rats (streptozotocin induced). Oral application of water extracts at doses of 40 and 80 mg/kg, ethanolic (112 mg/kg) and butanolic (80 mg/kg) extracts significantly lowered the plasma glucose levels in diabetic rats within three hours. Glibenclamide and metformin were used as references and showed similar hypoglycemic effects like the extracts. The three extracts have a similar chemical composition (HPLC analysis).
journal_name
J Ethnopharmacoljournal_title
Journal of ethnopharmacologyauthors
Andrade-Cetto A,Martínez-Zurita E,Wiedenfeld Hdoi
10.1016/j.jep.2005.03.021keywords:
subject
Has Abstractpub_date
2005-09-14 00:00:00pages
319-22issue
3eissn
0378-8741issn
1872-7573pii
S0378-8741(05)00226-6journal_volume
100pub_type
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journal_title:Journal of ethnopharmacology
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journal_title:Journal of ethnopharmacology
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