Hypoglycemic effect of Malmea depressa root on streptozotocin diabetic rats.

Abstract:

:The hypoglycemic effects of water, ethanolic and butanolic extracts prepared from the root of Malmea depressa (Baill) R.E. Fries. (Annonaceae) were studied in diabetic rats (streptozotocin induced). Oral application of water extracts at doses of 40 and 80 mg/kg, ethanolic (112 mg/kg) and butanolic (80 mg/kg) extracts significantly lowered the plasma glucose levels in diabetic rats within three hours. Glibenclamide and metformin were used as references and showed similar hypoglycemic effects like the extracts. The three extracts have a similar chemical composition (HPLC analysis).

journal_name

J Ethnopharmacol

authors

Andrade-Cetto A,Martínez-Zurita E,Wiedenfeld H

doi

10.1016/j.jep.2005.03.021

keywords:

subject

Has Abstract

pub_date

2005-09-14 00:00:00

pages

319-22

issue

3

eissn

0378-8741

issn

1872-7573

pii

S0378-8741(05)00226-6

journal_volume

100

pub_type

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