当前位置： SCI文献检索 > JOURNAL OF ETHNOPHARMACOLOGY期刊下所有文献 > Is there an industrial future for phytopharmaceutical drugs? An outline of UNIDO programmes in the sector.

Is there an industrial future for phytopharmaceutical drugs? An outline of UNIDO programmes in the sector.

Abstract：

:Although a substantial proportion of the health-care expenditure of developing countries is spent on the acquisition of drugs, this is only sufficient to serve about a quarter of their population. Therefore it is inconceivable that WHO's goal of HEALTH FOR ALL by the year 2000 could even be approached without consideration being given to the role in health care systems of herbal medicines. In this endeavour, traditional herbal medicines must perforce be granted the benefits of modern science and technology to serve future global needs. Here we are addressing both a contigency situation as well as a long term one. In developing nations there is a dire need for an improved supply of therapeutic agents for a variety of diseases that are characteristic of deprivation and poverty. In addition herbal medicines promise to provide both concepts of therapy, as well as therapeutic agents in areas where modern medicine has few answers. UNIDO's programmes for technical assistance to developing nations aim at the fullest utilisation of traditional herbal-based pharmacopoeias in addressing both these situations. They have employed a multi-disciplinary approach to the industrial production of herbal medicines. The projects endeavour to utilise the natural flora, judiciously, for selection, domestication and crop-wise cultivation of medicinal plant species for industrial processing. National R & D efforts have been strengthened to include the development of expertise in several areas such as instrumental analyses, biological assessment of raw materials as well as products. Process technology development has received special attention. A versatile poly-functional pilot plant has been developed to enable the production of herbal preparations as well as extracts and phytochemicals.(ABSTRACT TRUNCATED AT 250 WORDS)

journal_name

J Ethnopharmacol

journal_title

Journal of ethnopharmacology

authors

Wijesekera RO

doi

10.1016/0378-8741(91)90121-s

subject

Has Abstract

pub_date

1991-04-01 00:00:00

pages

217-24

issue

1-3

eissn

0378-8741

issn

1872-7573

pii

0378-8741(91)90121-S

journal_volume

32

pub_type

杂志文章

相关文献

JOURNAL OF ETHNOPHARMACOLOGY文献大全
  • LC-MS characterized methanolic extract of zanthoxylum armatum possess anti-breast cancer activity through Nrf2-Keap1 pathway: An in-silico, in-vitro and in-vivo evaluation.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Zanthoxylum armatum DC (Rutaceae) containing flavonoids, alkaloids, coumarins, lignans, amides and terpenoid is well-known for its curative properties against various ailments including cancer. In the current research, phytochemicals present in the methanolic extract of Zanthoxylum armatu...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2020.113758

    authors： Sahu R,Kar RK,Sunita P,Bose P,Kumari P,Bharti S,Srivastava S,Pattanayak SP

    更新日期：2021-04-06 00:00:00

  • Evaluation of the diuretic activity in two Mexican medicinal species: Selaginella nothohybrida and Selaginella lepidophylla and its effects with ciclooxigenases inhibitors.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Doradilla is a plant that has a long history in the Mexican traditional system of medicine for gall and renal stones, diuresis, stomach and liver inflammation among other diseases. Major components isolated from these plants include biflavonoids as amentoflavone (1), robustaflavone (2) an...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2015.01.031

    authors： Aguilar MI,Benítez WV,Colín A,Bye R,Ríos-Gómez R,Calzada F

    更新日期：2015-04-02 00:00:00

  • Systems pharmacology strategies for drug discovery and combination with applications to cardiovascular diseases.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Multi-target therapeutics is a promising paradigm for drug discovery which is expected to produce greater levels of efficacy with fewer adverse effects and toxicity than monotherapies. Medical herbs featuring multi-components and multi-targets may serve as valuable resources for network-b...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2013.07.001

    authors： Li P,Chen J,Wang J,Zhou W,Wang X,Li B,Tao W,Wang W,Wang Y,Yang L

    更新日期：2014-01-01 00:00:00

  • Safety evaluation of neem (Azadirachta indica) derived pesticides.

    abstract：:The neem tree, Azadirachta indica, provides many useful compounds that are used as pesticides and could be applied to protect stored seeds against insects. However in addition to possible beneficial health effects, such as blood sugar lowering properties, anti-parasitic, anti-inflammatory, anti-ulcer and hepatoprotect...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jep.2004.05.011

    authors： Boeke SJ,Boersma MG,Alink GM,van Loon JJ,van Huis A,Dicke M,Rietjens IM

    更新日期：2004-09-01 00:00:00

  • Antidepressant-like effect of the extracted of Kai Xin San, a traditional Chinese herbal prescription, is explained by modulation of the central monoaminergic neurotransmitter system in mouse.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Kai Xin San (KXS) is a traditional Chinese herbal prescription for the treatment of depression-like disorders, anxiety, and impairment in learning and memory, however, there is very little scientific data concerning the efficacy of this. AIM OF THE STUDY:The present study aimed to invest...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2011.11.027

    authors： Zhou XJ,Liu M,Yan JJ,Cao Y,Liu P

    更新日期：2012-01-31 00:00:00

  • Antiplasmodial activity of plant extracts used in west African traditional medicine.

    abstract：:Five plants originating from Ivory Coast were selected after an ethnobotanical survey, Alchornea cordifolia, Mitragyna inermis, Nauclea diderrichii, Pterocarpus santalinoides, and Terminalia glaucescens. Traditional healers for the treatment of malaria commonly used these plants. Extracts of these plants were tested o...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/s0378-8741(00)00296-8

    authors： Mustofa,Valentin A,Benoit-Vical F,Pélissier Y,Koné-Bamba D,Mallié M

    更新日期：2000-11-01 00:00:00

  • Evaluation of the toxicity of Solanum lycocarpum in the reproductive system of male mice and rats.

    abstract：:Powdered Solanum lycocarpum fruit is commonly used to treat diabetes, but apparently no studies have been conducted to evaluate potential adverse side effects. In the present paper the toxic effect of S. lycocarpum was evaluated in adult male Wistar rats and Swiss mice. The administration of an aqueous extract prepare...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/s0378-8741(00)00250-6

    authors： de Cássia da SeSá R,Vireque AA,Reis JE,Guerra MO

    更新日期：2000-11-01 00:00:00

  • Dangnyohwan improves glucose utilization and reduces insulin resistance by increasing the adipocyte-specific GLUT4 expression in Otsuka Long-Evans Tokushima Fatty rats.

    abstract：AIM OF THE STUDY:Dangnyohwan (DNH) has been used for treatment of diabetes mellitus. However, the exact cellular and molecular mechanisms underlying the beneficial effects of DNH are not well understood. Therefore, we investigated how DNH improves hyperglycemia and insulin resistance in obese-type diabetes model. METH...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2007.10.040

    authors： Park SY,Choi YH,Lee W

    更新日期：2008-02-12 00:00:00

  • Effect of Tribulus terrestris on nicotinamide adenine dinucleotide phosphate-diaphorase activity and androgen receptors in rat brain.

    abstract：:Tribulus terrestris L. (Zygophyllaceae) have been used as an aphrodisiac both in the Indian and Chinese traditional systems of medicine. Administration of Tribulus terrestris extract (TT) increased sexual behaviour and intracavernous pressure both in normal and castrated rats and these effects were probably due to the...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2004.08.030

    authors： Gauthaman K,Adaikan PG

    更新日期：2005-01-04 00:00:00

  • Effects of Hemerocallis flava on motor activity and the concentration of central monoamines and its metabolites in rats.

    abstract：:In this study, we used behavioral and biochemical methods to investigate the effects of Hemerocallis flava (Liliaceae) (abbreviated as HF) on motor activity and the concentration of monoamines in rats. The water fraction of the resuspended HF extract was most active in reducing the motility in rats. The water fraction...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/0378-8741(96)01388-8

    authors： Hsieh MT,Ho YF,Peng WH,Wu CR,Chen CF

    更新日期：1996-06-01 00:00:00

  • Antioxidative and hepatoprotective effect of CGX, an herbal medicine, against toxic acute injury in mice.

    abstract：AIM:CGX, a modified traditional Chinese herbal drug whose name means "liver cleaning," is used to treat various liver disorders. This study investigated the protective effects of CGX and its mechanisms. MATERIAL AND METHODS:After pretreating ICR mice twice daily with CGX (po, 50 or 100mg/kg) or distilled water for thr...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2008.07.042

    authors： Hu XP,Shin JW,Wang JH,Cho JH,Son JY,Cho CK,Son CG

    更新日期：2008-10-30 00:00:00

  • Ethnopharmacological survey of medicinal herbs in Jordan, the Ajloun Heights region.

    abstract：:The study of local knowledge about natural resources is becoming increasingly important in defining strategies and actions for conservation of medicinal plants. This study therefore sought to collect information from local population concerning the use of Ajloun Heights region medicinal plants; identify the most impor...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2006.09.031

    authors： Aburjai T,Hudaib M,Tayyem R,Yousef M,Qishawi M

    更新日期：2007-03-21 00:00:00

  • Maimendong and Qianjinweijing Tang (Jin formula) suppresses lung cancer by regulation of miR-149-3p.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Maimendong and Qianjinweijing Tang (Jin formula), a classic Chinese formula, can enhance therapeutic efficacy and reduce adverse effects in patients with lung cancer. AIM OF THE STUDY:To evaluate the anti-lung cancer effect of Jin formula in vivo and in vitro, and to explore the role of ...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2020.112836

    authors： Jiang Z,Ma Y,Tian T,Sun Y,Chen H,Lu Y,Wu Y,Jiang H,Li W,Li L,Zhou H,Wu M

    更新日期：2020-08-10 00:00:00

  • Cytotoxic and genotoxic effects of aqueous extracts of five medicinal plants on Allium cepa Linn.

    abstract：:The cytotoxic and genotoxic effects of aqueous extracts of five medicinal plants: Azadirachta indica (A. Juss), Morinda lucida (Benth.), Cymbopogon citratus (DC Stapf.), Mangifera indica (Linn.) and Carica papaya (Linn.) was evaluated using the Allium cepa assay. The extracts were prepared with tap water as practised ...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2007.04.014

    authors： Akinboro A,Bakare AA

    更新日期：2007-07-25 00:00:00

  • Plumeria rubra L.- A review on its ethnopharmacological, morphological, phytochemical, pharmacological and toxicological studies.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Plumeria rubra L. (Apocynaceae) is a deciduous, commonly ornamental, tropical plant grown in home premises, parks, gardens, graveyards, because of its beautiful and attractive flowers of various colours and size. The different parts of the plant are used traditionally to treat various dis...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jep.2020.113291

    authors： Bihani T

    更新日期：2021-01-10 00:00:00

  • Involvement of mTOR/Survivin signaling pathway in TUA(2β, 3β, 23-trihydroxy-urs-12-ene-28-olic acid)-induced apoptosis in human gastric cancer cell line BGC823 cells.

    abstract：ETHNO-PHARMACOLOGICAL RELEVANCE:A natural ursolic compound, 2β,3β,23-trihydroxy-urs-12-ene-28-olic acid (TUA) was isolated from the root of Actinidiafulvicoma Hance. (A.fulvicoma Radix), which is used as a traditional hebal medicine to cure innominate inflammation of unknown origin of the digestive tract in the She nat...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2020.113437

    authors： Cheng Q,Li Y,Guo X,Li H

    更新日期：2021-03-01 00:00:00

  • Pharmacokinetics comparative study of a novel Chinese traditional herbal formula and its compatibility.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Da Chuan Xiong Decoction Compound preparation (DCXDCP), the formulation of a classical Chinese prescription recorded in "Xuanminglunfang", was clinically employed to treat migraine's disease. AIM OF THE STUDY:In order to investigate the influence of compatibility on the pharmacokinetics ...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2011.05.007

    authors： Zheng Q,Yue PF,Wu B,Hu PY,Wu ZF,Yang M

    更新日期：2011-09-01 00:00:00

  • Antimicrobial properties of Honduran medicinal plants.

    abstract：:Ninety-two plants used in the traditional pharmacopoeia of the Pech and neighboring Mestizo peoples of central Honduras are reported. The results of in vitro antimicrobial screens showed that 19 of the extracts from medicinal plants revealed signs of antifungal activity while 22 demonstrated a measurable inhibitory ef...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/s0378-8741(98)00100-7

    authors： Lentz DL,Clark AM,Hufford CD,Meurer-Grimes B,Passreiter CM,Cordero J,Ibrahimi O,Okunade AL

    更新日期：1998-12-01 00:00:00

  • Suppressive effects of methoxyflavonoids isolated from Kaempferia parviflora on inducible nitric oxide synthase (iNOS) expression in RAW 264.7 cells.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:The rhizomes of Kaempferia parviflora Wall. ex Baker have been traditionally used in Thailand to treat abscesses, gout, and peptic ulcers. AIM:Previously, we reported that the chloroform fraction of a Kaempferia parviflora extract had an inhibitory effect on rat paw-edema. In the present...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2011.01.013

    authors： Sae-Wong C,Matsuda H,Tewtrakul S,Tansakul P,Nakamura S,Nomura Y,Yoshikawa M

    更新日期：2011-07-14 00:00:00

  • Protective effect of the aqueous leaf and seed extract of Phyllanthus amarus on gentamicin and acetaminophen-induced nephrotoxic rats.

    abstract：AIM OF THE STUDY:In African traditional medicine, different parts of Phyllanthus amarus Schum. and Thonn. (family: Euphorbiaceae) are highly valued for the treatment of array of human diseases including hepatic and urolithic and/or other renal diseases. In the present study, single oral 100-400mg/kg/day of the leaf and...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2008.04.025

    authors： Adeneye AA,Benebo AS

    更新日期：2008-07-23 00:00:00

  • Ethnopharmacological survey on medicinal plants used in herbal drinks among the traditional communities of Pakistan.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:There is very limited information regarding medicinal plants used by traditional healers in Pakistan, for treating wide-ranging diseases. Current study provides significant ethnopharmacological information, both qualitative and quantitative on medical plants in Pakistan and the pharmacolo...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2016.02.039

    authors： Ahmad M,Khan MP,Mukhtar A,Zafar M,Sultana S,Jahan S

    更新日期：2016-05-26 00:00:00

  • Asian elephant self-medication as a source of ethnoveterinary knowledge among Karen mahouts in northern Thailand.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Ethnoveterinary medicine is often assumed to be a subset of human medicinal knowledge. Here we investigate the possibility that some ethnoveterinary medicine rather originates from observations of animal self-medication. We document and analyze the ethnoveterinary medicine used by Karen m...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2020.112823

    authors： Greene AM,Panyadee P,Inta A,Huffman MA

    更新日期：2020-09-15 00:00:00

  • The influence of Bauhinia forficata Link subsp. pruinosa tea on lipid peroxidation and non-protein SH groups in human erythrocytes exposed to high glucose concentrations.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Bauhinia forficata (BF) has been traditionally used as tea in folk medicine of Brazil for treatment of Diabetes mellitus (DM). AIM OF THE STUDY:To evaluate the effects of BF leaf tea on markers of oxidative damage and antioxidant levels in an experimental model of hyperglycemia in human ...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2013.03.070

    authors： Salgueiro AC,Leal CQ,Bianchini MC,Prado IO,Mendez AS,Puntel RL,Folmer V,Soares FA,Avila DS,Puntel GO

    更新日期：2013-06-21 00:00:00

  • Crude terpene glycoside component from Radix paeoniae rubra protects against isoproterenol-induced myocardial ischemic injury via activation of the PI3K/AKT/mTOR signaling pathway.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Radix paeoniae rubra, also known as chishao (CS), is a frequently used traditional Chinese medicine that can promote blood circulation to remove blood stasis. It has been widely used for the prevention and treatment of cardiovascular diseases in China. Although terpene glycoside (TG), the...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2017.05.028

    authors： Ke Z,Wang G,Yang L,Qiu H,Wu H,Du M,Chen J,Song J,Jia X,Feng L

    更新日期：2017-07-12 00:00:00

  • Behavioral effects of Euphorbia hirta L.: sedative and anxiolytic properties.

    abstract：:Lyophilised aqueous extract of Euphorbia hirta L. (Euphorbiaceae) has been evaluated for behavioral effects in mice. The extract did not induce any toxic effect when it was administered i.p. and orally. Sedative properties could be confirmed with high doses (100 mg of dried plant/kg, and more), by a decrease of behavi...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/0378-8741(90)90055-x

    authors： Lanhers MC,Fleurentin J,Cabalion P,Rolland A,Dorfman P,Misslin R,Pelt JM

    更新日期：1990-05-01 00:00:00

  • A comprehensive quality evaluation of Fuzi and its processed product through integration of UPLC-QTOF/MS combined MS/MS-based mass spectral molecular networking with multivariate statistical analysis and HPLC-MS/MS.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Aconiti Lateralis Radix Praeparata (the Chinese name is Fuzi, FZ), the lateral or daughter root of Aconitum carmichaelii Debx. (Ranunculaceae), is a controversial traditional Chinese medicine (TCM) that is universally distributed and applied in many countries, such as China, Japan, Korea,...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2020.113455

    authors： Lei H,Zhang Y,Ye J,Cheng T,Liang Y,Zu X,Zhang W

    更新日期：2021-02-10 00:00:00

  • Anti-hyperglycemic effect of Eugenia jambolana and Tinospora cordifolia in experimental diabetes and their effects on key metabolic enzymes involved in carbohydrate metabolism.

    abstract：:In India, the decoction of kernels of Eugenia jambolana (EJ) and extracts of Tinospora cordifolia (TC) are used as a household remedy for diabetes. These also form constituents of many herbal formulations for diabetes that are marketed in this country. The anti-hyperglycemic effect of aqueous and alcoholic extracts as...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/s0378-8741(00)00319-6

    authors： Grover JK,Vats V,Rathi SS

    更新日期：2000-12-01 00:00:00

  • In vitro antiplasmodial activity of extracts and fractions from seven medicinal plants used in the Democratic Republic of Congo.

    abstract：:The in vitro antiplasmodial activity of seven EtOH extracts and twenty fractions from the partition of the initial ethanolic extracts from seven African medicinal plants used in the Democratic Republic of Congo (DR Congo) for the treatment of malaria was evaluated. The most active EtOH extracts (IC50 < 3 microg/ml) we...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2004.02.022

    authors： Tona L,Cimanga RK,Mesia K,Musuamba CT,De Bruyne T,Apers S,Hernans N,Van Miert S,Pieters L,Totté J,Vlietinck AJ

    更新日期：2004-07-01 00:00:00

  • Pharmacological potential and conservation prospect of the genus Eucomis (Hyacinthaceae) endemic to southern Africa.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:The genus Eucomis (Hyacinthaceae) consists of 10 species that are extensively used in African traditional medicine. This review is an appraisal of current information on the distribution and morphology, traditional uses, pharmacology, toxicology and approaches devised to enhance the conse...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jep.2013.11.002

    authors： Masondo NA,Finnie JF,Van Staden J

    更新日期：2014-01-01 00:00:00

  • The ambrosanolide cumanin inhibits macrophage nitric oxide synthesis: some structural considerations.

    abstract：:Since its role in inflammatory diseases was recognized, nitric oxide (NO) has become an important mediator to evaluate anti-inflammatory agents. Sesquiterpene lactones, which occur in several medicinal plants, inhibit the NO production in macrophage-like cells. This action is probably due to a 1,4 addition reaction be...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2004.07.020

    authors： Lastra AL,Ramírez TO,Salazar L,Martínez M,Trujillo-Ferrara J

    更新日期：2004-12-01 00:00:00