Abstract：
:The loss or failure of an organ or tissue is one of the most frequent, devastating, and costly problems in healthcare. Current treatment modalities include transplantation of organs, surgical reconstruction, use of mechanical devices, or supplementation of metabolic products. A new field, tissue engineering, applies the principles and methods of engineering, material science, and cell and molecular biology toward the development of viable substitutes which restore, maintain, or improve the function of human tissues. In this review, we outline the opportunities and challenges of this emerging interdisciplinary field and its attempts to provide solutions to tissue creation and repair. Within this context, we present our experience using the basic tools of tissue engineering to guide regeneration of diverse tissues that include the liver, small intestine, cardiovascular structures, nerve, and cartilage. And in addition, we discuss the necessity of finding new strategies to achieve vascularization of complex tissues for transplant and present our approaches utilizing MicroElectroMechanical Systems (MEMS) technology and three-dimensional printing.
journal_name
World J Surgjournal_title
World journal of surgeryauthors
Lalan S,Pomerantseva I,Vacanti JPdoi
10.1007/s00268-001-0131-3keywords:
subject
Has Abstractpub_date
2001-11-01 00:00:00pages
1458-66issue
11eissn
0364-2313issn
1432-2323journal_volume
25pub_type
杂志文章,评审abstract：BACKGROUND:Seroma formation is a frequent postoperative complication following open ventral hernia repair (OVHR), especially in cases requiring wide subcutaneous dissection (WSD). The aim of this study was to evaluate the effectiveness of a new low-thrombin fibrin sealant for seroma prevention. METHODS:A total of 60 c...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-014-2691-z
更新日期：2014-11-01 00:00:00
abstract：:The expression of Fas ligand on tumor cells may counterattack the host's immunity and worsen the prognosis. Knowledge of the prognostic impact of Fas ligand on patients with hepatocellular carcinoma (HCC) after hepatectomy is still limited. Fas ligand expression in HCCs was examined in 59 patients who underwent hepate...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-004-7254-2
更新日期：2004-08-01 00:00:00
abstract：:The evaluation of screening programs for cancer is considered. Initial evaluation has to be in terms of mortality, but increasing importance should be attached to measures which evaluate the interaction of early detection with the disease process. These include the degree to which diagnosis is advanced, both in time a...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/BF01671147
更新日期：1989-01-01 00:00:00
abstract：:In a prospective multicenter study, 186 patients with squamous cell esophageal carcinoma, who after evaluation were considered suitable for surgery, were randomized to 4 treatment groups: Group 1, surgery alone; Group 2, pre-operative chemotherapy (cisplatin and bleomycin) and surgery; Group 3, pre-operative irradiati...
journal_title：World journal of surgery
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1007/BF02067069
更新日期：1992-11-01 00:00:00
abstract：:Duodenal leiomyomas are rare neoplasms and when present are usually asymptomatic. There are, however, isolated case reports of such leiomyomas giving rise to complications including gastrointestinal hemorrhage and obstruction. The purpose of this study was to review the surgical experience with duodenal leiomyomas at ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002680020083
更新日期：2001-05-01 00:00:00
abstract：INTRODUCTION:The role for diverting ostomy as a method to help reduce morbidity and mortality has been well established in the combat trauma population. However, factors that influence the type of ostomy used and which ostomies become permanent are poorly studied. We examine patterns of ostomy usage and reversal in a l...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-018-4759-7
更新日期：2019-01-01 00:00:00
abstract：:Burn patients develop a number of physiologic alterations among which is a markedly increased metabolic rate. Other metabolic changes include an increased rate of glucose production and utilization, a decreased rate of lipid metabolism, and an increased rate of both protein catabolism and anabolism. These alterations ...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/BF02067118
更新日期：1992-01-01 00:00:00
abstract：BACKGROUND:Congenital diaphragmatic hernia (CDH) continues to be associated with significant mortality and morbidity rates despite advances in neonatal care. Fetal intervention for CDH has been studied for 25 years. After initial difficulties encountered with open fetal repair, attention has turned to tracheal occlusio...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-007-9074-7
更新日期：2007-08-01 00:00:00
abstract：BACKGROUND:The survival impact of distal pancreatectomy (DP) with celiac axis resection for locally advanced pancreatic body/tail cancer remains unclear. METHODS:A total of 16 patients underwent DP with celiac axis resection, while 76 underwent standard DP for pancreatic body/tail cancer. The indications for DP with c...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-016-3670-3
更新日期：2017-01-01 00:00:00
abstract：BACKGROUND:The only potential cure for neuroendocrine tumors (NETs) is operative resection, which may also offer a survival benefit for advanced disease. We aimed to assess the role of 68Ga-DOTATATE PET/CT in preoperative planning and compared its performance to CT with IV contrast and MRI with Eovist®, for abdominal N...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-019-05216-3
更新日期：2020-02-01 00:00:00
abstract：:Different types of vagotomy have been widely used in the treatment of peptic ulcer disease. A close relationship between the vagus nerve and the release or action of gastrointestinal hormones is necessary for the optimal activation of the gastrointestinal tract. The serum concentrations of the antral hormone gastrin a...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/BF01654771
更新日期：1979-09-20 00:00:00
abstract：BACKGROUND:Concurrent vitamin D(3) deficiency is common in primary hyperparathyroidism (pHPT). We aimed to examine the clinicopathologic features and short-term outcomes of vitamin D(3)-deficient patients after minimally invasive parathyroidectomy (MIP). METHODS:Over 2-year period, 80 consecutive MIP patients had preo...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-009-0377-8
更新日期：2010-06-01 00:00:00
abstract：:Blood loss during liver transection and ischemia-reperfusion injury associated with hepatic inflow occlusion are significant drawbacks during liver surgery. Sixteen patients underwent liver resection using the Monopolar Floating Ball (FB) plus LigaSure (LS) diathermy without occlusion of the hepatoduodenal ligament (g...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-003-7167-5
更新日期：2004-02-01 00:00:00
abstract：INTRODUCTION:Large-bowel obstruction and perforation are still frequently occurring entities for the acute care surgeon. In these cases, Hartmann's procedure is the most commonly used surgical technique. However, recent papers demonstrate that colon resection and primary anastomosis (RPA) in the emergency setting is a ...
journal_title：World journal of surgery
pub_type： 临床试验,杂志文章
doi：10.1007/s00268-012-1513-4
更新日期：2012-05-01 00:00:00
abstract：BACKGROUND:In the last decade, robotic video-assisted thoracic surgery (R-VATS) has grown significantly and consolidated as an alternative to video-assisted thoracic surgery. The objective of this study is to present the implementation as well as the experience with R-VATS accumulated by 2 Brazilian groups. We also com...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-019-05086-9
更新日期：2019-11-01 00:00:00
abstract：BACKGROUND:Management of critically ill patients is challenging in a low-resource setting. In Rwanda, peritonitis is a common surgical condition where patients often present late, with advanced disease. We aim to describe critical care management of patients with peritonitis in Rwanda. METHODS:Data were collected at a...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-018-4598-6
更新日期：2018-10-01 00:00:00
abstract：INTRODUCTION:The coexistence of an enterocutaneous fistula (ECF) with large abdominal wall defects represent one of the most demanding situations seen by a surgeon. Simultaneous treatment of ECF closure with abdominal wall defect closure has been widely debated. Our objective was to determine if the type of abdominal w...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-020-05635-7
更新日期：2020-10-01 00:00:00
abstract：OBJECTIVE:The present study was designed to evaluate functional outcome of perineal repair with and without levatorplasty versus transanal repair of rectocele in obstructed defecation. METHODS AND PATIENTS:A total of 48 multiparous women with obstructed defecation caused by a rectocele were randomly allocated to three...
journal_title：World journal of surgery
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00268-010-0390-y
更新日期：2010-04-01 00:00:00
abstract：:We sought to determine whether early eschar excision en masse (EEE) at one operation would be effective in the prevention and treatment of postburn organ dysfunction (OD) and multiple organ dysfunction syndrome (MODS). A total of 60 patients, with total body surface burned area over 35% and a third degree burn area ov...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002689900661
更新日期：1999-12-01 00:00:00
abstract：:Enteral nutrition (EN) and total parenteral nutrition (TPN) may provide life-sustaining therapy for surgical patients. The duration of nutritional therapy (enteral or parenteral) implies distinct access routes. We review the main aspects related to access routes for nutrient delivery. The enteral route, whenever feasi...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s002680010264
更新日期：2000-12-01 00:00:00
abstract：BACKGROUND:The aim of this work was to study the impact of anemia on surgical outcomes and the impact of instituting appropriate workup and treatment of anemia on surgical outcomes. METHODS:We conducted a case-control retrospective chart review of all hernia repair, hydrocele repair, and hysterectomy cases at the SEAR...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-012-1615-z
更新日期：2012-09-01 00:00:00
abstract：:Surgical treatment of adenomas may become necessary when the base of the polyp is too wide for snaring, increasing the risk of incomplete removal or perforation of the bowel wall. Suspicion of malignancy may also indicate surgery. Multiple adenomas not controlled by snare polypectomy can be treated by colectomy. The d...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF01658955
更新日期：1991-01-01 00:00:00
abstract：:There has been a long, unresolved debate regarding the operation of choice for well differentiated carcinoma of the thyroid. We therefore analyzed the feasibility, scope, sample size, and length of follow-up required to determine the optimal operation for papillary thyroid carcinoma. A statistical approach was used to...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s002689900016
更新日期：1996-01-01 00:00:00
abstract：BACKGROUND:Neuroendocrine neoplasias (NEN) of the gastroenteropancreatic (GEP) system frequently present with metastatic deposits. The proliferation marker Ki-67 is used for diagnosis and to assess the prognosis of disease. The aim of our study was to evaluate the usefulness of Ki-67 % in the assessment of NEN patients...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-014-2451-0
更新日期：2014-06-01 00:00:00
abstract：:The past decade has seen a maturation of the art and science of perioperative nutritional support. We now have sufficient data to make informed and reasonable judgments regarding when we should and should not provide perioperative TPN. These judgments can be considered medically sound and fiscally responsible. The fol...
journal_title：World journal of surgery
pub_type： 临床试验,杂志文章,随机对照试验,评审
doi：10.1007/BF01658923
更新日期：1993-03-01 00:00:00
abstract：:In some patients, bile ducts of segments 2 and 3 (B2 and B3) run caudally to the umbilical portion of the left portal vein (UP)--an infraportal course. We aimed to evaluate the frequency and clinical implications of this variation. Between January 1992 and October 2000, 108 patients underwent resection for hilar chola...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-002-6544-9
更新日期：2002-12-01 00:00:00
abstract：:The success of parathyroid surgery is determined by the identification and removal of all parathyroid tumors. Parathyroid tumors accumulate and retain 2-methoxyisobutylisonitrile (MIBI) labeled with technetium-99m. Intravenous injection of this radiopharmacon prior to parathyroid surgery allows identification of parat...
journal_title：World journal of surgery
pub_type： 临床试验,杂志文章
doi：10.1007/s002689900427
更新日期：1998-06-01 00:00:00
abstract：BACKGROUND:The Lancet Commission on Global Surgery showed that countries with surgeon, anesthetist, and obstetrician (SAO) densities of 20-40 SAO/100,000 population were associated with improved health outcomes and recommended a global surgical workforce scale-up by 2030. Whether countries would be able to achieve such...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-019-05329-9
更新日期：2020-04-01 00:00:00
abstract：BACKGROUND:Surgery for Graves' disease (GD) is usually performed after adequate control with medical treatment. Occasionally, rapid pre-operative optimization is required. The primary objective was to compare the outcomes of patients undergoing elective surgery for well-controlled GD with those undergoing rapid pre-ope...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-019-05125-5
更新日期：2019-12-01 00:00:00
abstract：:We have previously demonstrated that there are two subgroups of patients with different types of biliary bile acid output after relief of obstructive jaundice by percutaneous transhepatic biliary drainage (PTBD). The reason for two groups is not clear but is possibly the difference in hepatic reserve function. The aim...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-001-0249-3
更新日期：2002-04-01 00:00:00
